Overexpression of aromatase associated with loss of heterozygosity of the STK11 gene accounts for prepubertal gynecomastia in boys with peutz-Jeghers syndrome

Journal of Clinical Endocrinology and Metabolism

Volumn 98, Issue 12, 2013, Pages

  Ham, Seungmin ^a,b   Meachem, Sarah J ^a,c   Choong, Catherine S ^f,g   Charles, Adrian K ^g   Baynam, Gareth S ^a,g,h,i,j   Jones, Timothy W ^f,g   Samarajeewa, Nirukshi U ^a,d   Simpson, Evan R ^a,e   Brown, Kristy A ^a,d  

^a HUDSON INSTITUTE OF MEDICAL RESEARCH   (Australia)

^b Departments of Obstetrics and Gynecology   (Australia)

^c Anatomy and Developmental Biology   (Australia)

^d Physiology   (Australia)

^e MONASH UNIVERSITY   (Australia)

^f Departments of Paediatric Endocrinology   (Australia)

^g Paediatric Pathology ^*  (Australia)

^h UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

ⁱ MURDOCH UNIVERSITY   (Australia)

^j KING EDWARD MEMORIAL HOSPITAL   (Australia)

more..

Author keywords

[No Author keywords available]

Indexed keywords

AROMATASE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; LETROZOLE; PROTEIN KINASE LKB1; PROTEIN P21;

ADOLESCENT; ARTICLE; BONE AGE; BREAST EPITHELIUM; CASE REPORT; CHILD; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE LOCATION; GENE MUTATION; GENE OVEREXPRESSION; GENE SILENCING; GENE TARGETING; GENETIC ANALYSIS; GENETIC ASSOCIATION; GYNECOMASTIA; HETEROZYGOSITY LOSS; HUMAN; HUMAN TISSUE; MALE; MASTECTOMY; PEUTZ JEGHERS SYNDROME; PREPUBERTY; PRESCHOOL CHILD; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; REGULATOR GENE; SERTOLI CELL; SIGNAL TRANSDUCTION; STK11 GENE;

ADOLESCENT; AROMATASE; CELL NUCLEUS; CHILD, PRESCHOOL; GYNECOMASTIA; HUMANS; LOSS OF HETEROZYGOSITY; MALE; MAMMARY GLANDS, HUMAN; PEUTZ-JEGHERS SYNDROME; PROTEIN TRANSPORT; PROTEIN-SERINE-THREONINE KINASES; SERTOLI CELLS; TESTIS; TRANSCRIPTION FACTORS;

EID: 84889778022     PISSN: 0021972X     EISSN: 19457197     Source Type: Journal    
DOI: 10.1210/jc.2013-2291     Document Type: Article

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