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Volumn 46, Issue 18, 2013, Pages 1877-1883

Simultaneous determination of β-hydroxybutyrate and β-hydroxy-β-methylbutyrate in human whole blood using hydrophilic interaction liquid chromatography electrospray tandem mass spectrometry

Author keywords

Hydroxy methylbutyrate; Hydroxybutyrate; BHB; HMB; LC MS MS; Whole blood

Indexed keywords

3 HYDROXYBUTYRIC ACID; ACETONITRILE; BUTYRIC ACID DERIVATIVE; METHANOL;

EID: 84889647104     PISSN: 00099120     EISSN: 18732933     Source Type: Journal    
DOI: 10.1016/j.clinbiochem.2013.08.011     Document Type: Article
Times cited : (38)

References (35)
  • 1
    • 67349155546 scopus 로고    scopus 로고
    • Comparison of seizure reduction and serum fatty acid levels after receiving the ketogenic and modified Atkins diet
    • Porta N., Vallée L., Boutry E., Fontaine M., Dessein A.F., Joriot S., et al. Comparison of seizure reduction and serum fatty acid levels after receiving the ketogenic and modified Atkins diet. Seizure 2009, 18:359-364.
    • (2009) Seizure , vol.18 , pp. 359-364
    • Porta, N.1    Vallée, L.2    Boutry, E.3    Fontaine, M.4    Dessein, A.F.5    Joriot, S.6
  • 3
    • 84872166360 scopus 로고    scopus 로고
    • Suppression of oxidative stress by β-hydroxybutyrate, an endogenous histone deacetylase inhibitor
    • Shimazu T., Hirschey M.D., Newman J., He W., Shirakawa K., Le Moan N., et al. Suppression of oxidative stress by β-hydroxybutyrate, an endogenous histone deacetylase inhibitor. Science 2013, 339:211-214.
    • (2013) Science , vol.339 , pp. 211-214
    • Shimazu, T.1    Hirschey, M.D.2    Newman, J.3    He, W.4    Shirakawa, K.5    Le Moan, N.6
  • 4
    • 84858076944 scopus 로고    scopus 로고
    • The biochemistry of ketogenesis and its role in weight management, neurological disease and oxidative stress
    • McPherson P.A., McEneny J. The biochemistry of ketogenesis and its role in weight management, neurological disease and oxidative stress. J Physiol Biochem 2012, 68:141-151.
    • (2012) J Physiol Biochem , vol.68 , pp. 141-151
    • McPherson, P.A.1    McEneny, J.2
  • 5
    • 79959802475 scopus 로고    scopus 로고
    • 2-Deoxy-d-glucose treatment induces ketogenesis, sustains mitochondrial function, and reduces pathology in female mouse model of Alzheimer's disease
    • Yao J., Chen S., Mao Z., Cadenas E., Brinton R.D. 2-Deoxy-d-glucose treatment induces ketogenesis, sustains mitochondrial function, and reduces pathology in female mouse model of Alzheimer's disease. PLoS One 2011, 6:e21788.
    • (2011) PLoS One , vol.6
    • Yao, J.1    Chen, S.2    Mao, Z.3    Cadenas, E.4    Brinton, R.D.5
  • 6
    • 19444376784 scopus 로고    scopus 로고
    • Cerebral ketone body metabolism
    • Morris A.A. Cerebral ketone body metabolism. J Inherit Metab Dis 2005, 28:109-121.
    • (2005) J Inherit Metab Dis , vol.28 , pp. 109-121
    • Morris, A.A.1
  • 7
    • 33750110683 scopus 로고    scopus 로고
    • Fuel metabolism in starvation
    • Cahill G.F. Fuel metabolism in starvation. Annu Rev Nutr 2006, 26:1-22.
    • (2006) Annu Rev Nutr , vol.26 , pp. 1-22
    • Cahill, G.F.1
  • 9
    • 84883212259 scopus 로고    scopus 로고
    • Preliminary results on the post-mortem measurement of 3-beta-hydroxybutyrate in liver homogenates
    • Palmiere C., Mangin P., Werner D. Preliminary results on the post-mortem measurement of 3-beta-hydroxybutyrate in liver homogenates. Int J Legal Med 2013, 127:943-949.
    • (2013) Int J Legal Med , vol.127 , pp. 943-949
    • Palmiere, C.1    Mangin, P.2    Werner, D.3
  • 10
    • 0037387745 scopus 로고    scopus 로고
    • Diagnosis and treatment of diabetic ketoacidosis and the hyperglycemic hyperosmolar state
    • Chiasson J.L., Aris-Jilwan N., Bélanger R., Bertrand S., Beauregard H., Ekoé J.M., et al. Diagnosis and treatment of diabetic ketoacidosis and the hyperglycemic hyperosmolar state. CMAJ 2003, 168:859-866.
    • (2003) CMAJ , vol.168 , pp. 859-866
    • Chiasson, J.L.1    Aris-Jilwan, N.2    Bélanger, R.3    Bertrand, S.4    Beauregard, H.5    Ekoé, J.M.6
  • 12
    • 0001544644 scopus 로고
    • The effect of ketonemia on the course of epilepsy
    • Wilder R.M. The effect of ketonemia on the course of epilepsy. Mayo Clin Bull 1921, 2:307-308.
    • (1921) Mayo Clin Bull , vol.2 , pp. 307-308
    • Wilder, R.M.1
  • 13
    • 33846250398 scopus 로고    scopus 로고
    • Anticonvulsant mechanisms of the ketogenic diet
    • Bough K.J., Rho J.M. Anticonvulsant mechanisms of the ketogenic diet. Epilepsia 2007, 48:43-58.
    • (2007) Epilepsia , vol.48 , pp. 43-58
    • Bough, K.J.1    Rho, J.M.2
  • 14
    • 39449139944 scopus 로고    scopus 로고
    • Effects of beta-hydroxy-beta-methylbutyrate (HMB) on exercise performance and body composition across varying levels of age, sex, and training experience: a review
    • Wilson G.J., Wilson J.M., Manninen A.H. Effects of beta-hydroxy-beta-methylbutyrate (HMB) on exercise performance and body composition across varying levels of age, sex, and training experience: a review. Nutr Metab 2008, 5:1.
    • (2008) Nutr Metab , vol.5 , pp. 1
    • Wilson, G.J.1    Wilson, J.M.2    Manninen, A.H.3
  • 16
    • 0022366429 scopus 로고
    • Head-space gas-chromatographic determination of 3-hydroxybutyrate in plasma after enzymatic reactions, and the relationship among the three ketone bodies
    • Kimura M., Kobayashi K., Matsuoka A., Hayashi K. Head-space gas-chromatographic determination of 3-hydroxybutyrate in plasma after enzymatic reactions, and the relationship among the three ketone bodies. Clin Chem 1985, 31:596-598.
    • (1985) Clin Chem , vol.31 , pp. 596-598
    • Kimura, M.1    Kobayashi, K.2    Matsuoka, A.3    Hayashi, K.4
  • 17
    • 0025101673 scopus 로고
    • Improvement in the head-space gas-chromatographic method for determination of three ketone bodies in plasma
    • Kimura M., Ogasahara N., Kobayashi K., Hitoi A., Matsuoka A., Kimura Y. Improvement in the head-space gas-chromatographic method for determination of three ketone bodies in plasma. Clin Chem 1990, 36:160-161.
    • (1990) Clin Chem , vol.36 , pp. 160-161
    • Kimura, M.1    Ogasahara, N.2    Kobayashi, K.3    Hitoi, A.4    Matsuoka, A.5    Kimura, Y.6
  • 18
    • 0028333808 scopus 로고
    • Determination of ketone bodies in post-mortem blood by head-space gas chromatography
    • Felby S., Nielsen E. Determination of ketone bodies in post-mortem blood by head-space gas chromatography. Forensic Sci Int 1994, 64:83-88.
    • (1994) Forensic Sci Int , vol.64 , pp. 83-88
    • Felby, S.1    Nielsen, E.2
  • 19
    • 79954614849 scopus 로고    scopus 로고
    • Determination of ketone bodies in blood by headspace gas chromatography-mass spectrometry
    • Holm K.M.D., Linnet K., Rasmussen B.S., Pedersen A.J. Determination of ketone bodies in blood by headspace gas chromatography-mass spectrometry. J Anal Toxicol 2010, 34:549-554.
    • (2010) J Anal Toxicol , vol.34 , pp. 549-554
    • Holm, K.M.D.1    Linnet, K.2    Rasmussen, B.S.3    Pedersen, A.J.4
  • 20
    • 70350501855 scopus 로고    scopus 로고
    • Determination of β-hydroxybutyrate in blood and urine using gas chromatography-mass spectrometry
    • Hassan H.M.A., Cooper G.A.A. Determination of β-hydroxybutyrate in blood and urine using gas chromatography-mass spectrometry. J Anal Toxicol 2009, 33:502-507.
    • (2009) J Anal Toxicol , vol.33 , pp. 502-507
    • Hassan, H.M.A.1    Cooper, G.A.A.2
  • 21
    • 77952293636 scopus 로고    scopus 로고
    • The post-mortem relationship between beta-hydroxybutyrate (BHB), acetone and ethanol in ketoacidosis
    • Elliott S., Smith C., Cassidy D. The post-mortem relationship between beta-hydroxybutyrate (BHB), acetone and ethanol in ketoacidosis. Forensic Sci Int 2010, 198:53-57.
    • (2010) Forensic Sci Int , vol.198 , pp. 53-57
    • Elliott, S.1    Smith, C.2    Cassidy, D.3
  • 22
    • 0025374465 scopus 로고
    • Analysis of β-hydroxy-β-methyl butyrate in plasma by gas chromatography and mass spectrometry
    • Nissen S., Van Koevering M., Webb D. Analysis of β-hydroxy-β-methyl butyrate in plasma by gas chromatography and mass spectrometry. Anal Biochem 1990, 188:17-19.
    • (1990) Anal Biochem , vol.188 , pp. 17-19
    • Nissen, S.1    Van Koevering, M.2    Webb, D.3
  • 23
    • 56549131458 scopus 로고    scopus 로고
    • High-performance liquid chromatography determination of ketone bodies in human plasma by precolumn derivatization with p-nitrobenzene diazonium fluoroborate
    • Yamato S., Shinohara K., Nakagawa S., Kubota A., Inamura K., Watanabe G., et al. High-performance liquid chromatography determination of ketone bodies in human plasma by precolumn derivatization with p-nitrobenzene diazonium fluoroborate. Anal Biochem 2009, 384:145-150.
    • (2009) Anal Biochem , vol.384 , pp. 145-150
    • Yamato, S.1    Shinohara, K.2    Nakagawa, S.3    Kubota, A.4    Inamura, K.5    Watanabe, G.6
  • 24
    • 84856628887 scopus 로고    scopus 로고
    • Determination of gamma-hydroxybutyrate (GHB), beta-hydroxybutyrate (BHB), pregabalin, 1,4-butane-diol (1,4BD) and gamma-butyrolactone (GBL) in whole blood and urine samples by UPLC-MSMS
    • Dahl S.R., Olsen K.M., Strand D.H. Determination of gamma-hydroxybutyrate (GHB), beta-hydroxybutyrate (BHB), pregabalin, 1,4-butane-diol (1,4BD) and gamma-butyrolactone (GBL) in whole blood and urine samples by UPLC-MSMS. J Chromatogr B 2012, 885:37-42.
    • (2012) J Chromatogr B , vol.885 , pp. 37-42
    • Dahl, S.R.1    Olsen, K.M.2    Strand, D.H.3
  • 25
    • 0038706464 scopus 로고    scopus 로고
    • Gamma hydroxybutyric acid (GHB) concentrations in humans and factors affecting endogenous production
    • Elliott S.P. Gamma hydroxybutyric acid (GHB) concentrations in humans and factors affecting endogenous production. Forensic Sci Int 2003, 133:9-16.
    • (2003) Forensic Sci Int , vol.133 , pp. 9-16
    • Elliott, S.P.1
  • 26
    • 77953915671 scopus 로고    scopus 로고
    • Gamma-hydroxybutyrate in urine and serum: additional data supporting current cut-off recommendations
    • Andresen H., Sprys N., Schmoldt A., Mueller A., Iwersen-Bergmann S. Gamma-hydroxybutyrate in urine and serum: additional data supporting current cut-off recommendations. Forensic Sci Int 2010, 200:93-99.
    • (2010) Forensic Sci Int , vol.200 , pp. 93-99
    • Andresen, H.1    Sprys, N.2    Schmoldt, A.3    Mueller, A.4    Iwersen-Bergmann, S.5
  • 27
    • 0032983559 scopus 로고    scopus 로고
    • Prevalence of drugs used in cases of alleged sexual assault
    • ElSohly M.A., Salamone S.J. Prevalence of drugs used in cases of alleged sexual assault. J Anal Toxicol 1999, 23:141-146.
    • (1999) J Anal Toxicol , vol.23 , pp. 141-146
    • ElSohly, M.A.1    Salamone, S.J.2
  • 28
    • 35348862353 scopus 로고    scopus 로고
    • Prevalence of γ-hydroxybutyrate (GHB) in serum samples of amphetamine, metamphetamine and ecstasy impaired drivers
    • Dresen S., Kempf J., Weinmann W. Prevalence of γ-hydroxybutyrate (GHB) in serum samples of amphetamine, metamphetamine and ecstasy impaired drivers. Forensic Sci Int 2007, 173:112-116.
    • (2007) Forensic Sci Int , vol.173 , pp. 112-116
    • Dresen, S.1    Kempf, J.2    Weinmann, W.3
  • 29
    • 79954524398 scopus 로고    scopus 로고
    • Simultaneous determination of γ-hydroxybutyrate (GHB) and its analogues (GBL, 1.4-BD, GVL) in whole blood and urine by liquid chromatography coupled to tandem mass spectrometry
    • Johansen S.S., Windberg C.N. Simultaneous determination of γ-hydroxybutyrate (GHB) and its analogues (GBL, 1.4-BD, GVL) in whole blood and urine by liquid chromatography coupled to tandem mass spectrometry. J Anal Toxicol 2011, 35:8-14.
    • (2011) J Anal Toxicol , vol.35 , pp. 8-14
    • Johansen, S.S.1    Windberg, C.N.2
  • 30
    • 34247332999 scopus 로고    scopus 로고
    • Determination of GHB in urine and serum by LC/MS using a simple one-step derivative
    • Kaufmann E., Alt A. Determination of GHB in urine and serum by LC/MS using a simple one-step derivative. Forensic Sci Int 2007, 168:133-137.
    • (2007) Forensic Sci Int , vol.168 , pp. 133-137
    • Kaufmann, E.1    Alt, A.2
  • 31
    • 84865637029 scopus 로고    scopus 로고
    • A hydrophilic interaction liquid chromatography electrospray tandem mass spectrometry method for the simultaneous determination of γ-hydroxybutyrate and its precursors in forensic whole blood
    • Sørensen L.K., Hasselstrøm J.B. A hydrophilic interaction liquid chromatography electrospray tandem mass spectrometry method for the simultaneous determination of γ-hydroxybutyrate and its precursors in forensic whole blood. Forensic Sci Int 2012, 222:352-359.
    • (2012) Forensic Sci Int , vol.222 , pp. 352-359
    • Sørensen, L.K.1    Hasselstrøm, J.B.2
  • 32
    • 0345443559 scopus 로고
    • The specific introduction of an isopropylidene group in the synthesis of the monoterpene terpinolene and the sesquiterpene (±)-α-curcumene
    • Krapcho A.P., Jahngen E.G.E. The specific introduction of an isopropylidene group in the synthesis of the monoterpene terpinolene and the sesquiterpene (±)-α-curcumene. J Org Chem 1974, 39:1322-1324.
    • (1974) J Org Chem , vol.39 , pp. 1322-1324
    • Krapcho, A.P.1    Jahngen, E.G.E.2
  • 33
    • 0021259094 scopus 로고
    • Stable isotope dilution analysis of 3-hydroxyisovaleric acid in amniotic fluid: contribution to the prenatal diagnosis of inherited disorders of leucine catabolism
    • Jakobs C., Sweetman L., Nyhan W.L., Packman S. Stable isotope dilution analysis of 3-hydroxyisovaleric acid in amniotic fluid: contribution to the prenatal diagnosis of inherited disorders of leucine catabolism. J Inherit Metab Dis 1984, 7:15-20.
    • (1984) J Inherit Metab Dis , vol.7 , pp. 15-20
    • Jakobs, C.1    Sweetman, L.2    Nyhan, W.L.3    Packman, S.4
  • 34
    • 0003515157 scopus 로고
    • SO Standard 5725-2, accuracy (trueness and precision) of measurement methods and results-part 2
    • International Organization for Standardization, Geneva Switzerland
    • SO Standard 5725-2, accuracy (trueness and precision) of measurement methods and results-part 2. Basic method for the determination of repeatability and reproducibility of a standard measurement method 1994, International Organization for Standardization, Geneva Switzerland.
    • (1994) Basic method for the determination of repeatability and reproducibility of a standard measurement method
  • 35
    • 84884400014 scopus 로고
    • Evaluation of analytical methods used for regulation of foods and drugs
    • Horwitz W. Evaluation of analytical methods used for regulation of foods and drugs. Anal Chem 1982, 54:67A-76A.
    • (1982) Anal Chem , vol.54
    • Horwitz, W.1


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