메뉴 건너뛰기




Volumn 4, Issue 6, 2013, Pages 811-820

Contrast-induced nephropathy: Pharmacology, pathophysiology and prevention

Author keywords

Clinical pharmacology; Contrast media; Guidelines as topic; Kidney diseases; Pharmacokinetics

Indexed keywords


EID: 84889579081     PISSN: None     EISSN: 18694101     Source Type: Journal    
DOI: 10.1007/s13244-013-0291-3     Document Type: Review
Times cited : (91)

References (51)
  • 1
    • 84870329909 scopus 로고    scopus 로고
    • A European renal best practice (ERBP) position statement on the kidney disease improving global outcomes (KDIGO) clinical practice guidelines on acute kidney injury: Part 1: definitions, conservative managment and contrast-induced nephropathy
    • Fliser D, Laville M, Covic A, Fouque D, Vanholder R, Juillard L et al (2012) A European renal best practice (ERBP) position statement on the kidney disease improving global outcomes (KDIGO) clinical practice guidelines on acute kidney injury: Part 1: definitions, conservative managment and contrast-induced nephropathy. Nephrol Dial Transplant 27: 4263-4272.
    • (2012) Nephrol Dial Transplant , vol.27 , pp. 4263-4272
    • Fliser, D.1    Laville, M.2    Covic, A.3    Fouque, D.4    Vanholder, R.5    Juillard, L.6
  • 4
    • 46249083280 scopus 로고    scopus 로고
    • Contrast-induced nephropathy: The wheel has turned 360 degrees
    • Thomsen HS, Morcos SK, Barrett BJ (2008) Contrast-induced nephropathy: The wheel has turned 360 degrees. Acta Radiol 49: 646-657.
    • (2008) Acta Radiol , vol.49 , pp. 646-657
    • Thomsen, H.S.1    Morcos, S.K.2    Barrett, B.J.3
  • 5
    • 0036242067 scopus 로고    scopus 로고
    • Hospital-acquired renal insufficiency
    • Nash K, Hafeez A, Hou S (2002) Hospital-acquired renal insufficiency. Am J Kidney Dis 39: 930-936.
    • (2002) Am J Kidney Dis , vol.39 , pp. 930-936
    • Nash, K.1    Hafeez, A.2    Hou, S.3
  • 6
    • 78549267514 scopus 로고    scopus 로고
    • Contrast-induced acute kidney injury (CI-AKI) following intra-arterial administration of iodinated contrast media
    • Karlsberg RP, Dohad SY, Sheng R (2010) Contrast-induced acute kidney injury (CI-AKI) following intra-arterial administration of iodinated contrast media. J Nephrol 23: 658-666.
    • (2010) J Nephrol , vol.23 , pp. 658-666
    • Karlsberg, R.P.1    Dohad, S.Y.2    Sheng, R.3
  • 9
    • 84876791346 scopus 로고    scopus 로고
    • Contrast-induced acute kidney injury and clinical outcomes after intra-arterial and intravenous contrast administration: risk comparison adjusted for patient characteristics by design
    • Kooiman J, Le Haen PA, Gezgin G, De Vries JPP, Boersma D, Brulez HF et al (2013) Contrast-induced acute kidney injury and clinical outcomes after intra-arterial and intravenous contrast administration: risk comparison adjusted for patient characteristics by design. Am Heart J 165: 793-799.
    • (2013) Am Heart J , vol.165 , pp. 793-799
    • Kooiman, J.1    Le Haen, P.A.2    Gezgin, G.3    De Vries, J.P.P.4    Boersma, D.5    Brulez, H.F.6
  • 10
    • 33646131852 scopus 로고    scopus 로고
    • Risk of nephropathy after intravenous administration of contrast material: A critical literature analysis
    • Rao QA, Newhouse JH (2006) Risk of nephropathy after intravenous administration of contrast material: A critical literature analysis. Radiology 239: 392-397.
    • (2006) Radiology , vol.239 , pp. 392-397
    • Rao, Q.A.1    Newhouse, J.H.2
  • 11
    • 49149099592 scopus 로고    scopus 로고
    • Frequency of serum creatinine changes in the absence of iodinated contrast material: Implications for studies of contrast nephrotoxicity
    • Newhouse JH, Kho D, Rao QA, Starren J (2008) Frequency of serum creatinine changes in the absence of iodinated contrast material: Implications for studies of contrast nephrotoxicity. AJR Am J Roentgenol 191: 376-382.
    • (2008) AJR Am J Roentgenol , vol.191 , pp. 376-382
    • Newhouse, J.H.1    Kho, D.2    Rao, Q.A.3    Starren, J.4
  • 12
    • 84875410288 scopus 로고    scopus 로고
    • Frequency of acute kidney injury following intravenous contrast medium administration: A systematic review and meta-analysis
    • McDonald JS, McDonald RJ, Comin J, Wiliamson E, Katzberg RW, Hassan Murad M et al (2013) Frequency of acute kidney injury following intravenous contrast medium administration: A systematic review and meta-analysis. Radiology 276: 119-128.
    • (2013) Radiology , vol.276 , pp. 119-128
    • McDonald, J.S.1    McDonald, R.J.2    Comin, J.3    Wiliamson, E.4    Katzberg, R.W.5    Hassan Murad, M.6
  • 14
    • 84883201228 scopus 로고    scopus 로고
    • Contrast material-induced nephrotoxicity and intravenous low-osmolality contrast material: Risk stratification by using estimated glomerular filtration rate
    • Davenport MS, Khalatbari Sm Cohan RH, Dillman JR, Myles JD, Ellis JH (2013) Contrast material-induced nephrotoxicity and intravenous low-osmolality contrast material: Risk stratification by using estimated glomerular filtration rate. Radiology 268: 719-728.
    • (2013) Radiology , vol.268 , pp. 719-728
    • Davenport, M.S.1    Khalatbari, S.2    Cohan, R.H.3    Dillman, J.R.4    Myles, J.D.5    Ellis, J.H.6
  • 15
    • 0000919775 scopus 로고
    • The development of organic iodine compounds a x-ray contrast media
    • Wallingford VH (1953) The development of organic iodine compounds a x-ray contrast media. J Am Pharm Assoc (Baltim) 42: 721-728.
    • (1953) J Am Pharm Assoc (Baltim) , vol.42 , pp. 721-728
    • Wallingford, V.H.1
  • 17
    • 0002828018 scopus 로고    scopus 로고
    • History of iodinated contrast media
    • H. S. Thomson, R. N. Muller, and R. F. Mattrey (Eds.), Berlin Heidelberg New York: Springer
    • Pollack HM (1998) History of iodinated contrast media. In: Thomson HS, Muller RN, Mattrey RF (eds) Trends in contrast media. Springer, Berlin Heidelberg New York, pp 3-19.
    • (1998) Trends in Contrast Media , pp. 3-19
    • Pollack, H.M.1
  • 19
    • 0014558945 scopus 로고
    • Contrast agent design. Some aspects on the synthesis of water soluble contrast agents of low osmolality
    • Almen T (1969) Contrast agent design. Some aspects on the synthesis of water soluble contrast agents of low osmolality. Theor Biol 24: 216-226.
    • (1969) Theor Biol , vol.24 , pp. 216-226
    • Almen, T.1
  • 20
    • 0018166589 scopus 로고
    • Animal experiments and clinical experiences in cerebral angiography with a new contrast agent (ioxaglic acid) with a low hyperosmolality
    • Gonsette RE (1978) Animal experiments and clinical experiences in cerebral angiography with a new contrast agent (ioxaglic acid) with a low hyperosmolality. Ann Radiol (Paris) 21: 271-273.
    • (1978) Ann Radiol (Paris) , vol.21 , pp. 271-273
    • Gonsette, R.E.1
  • 21
    • 0020070075 scopus 로고
    • Nonionic dimer: development and initial testing of an intrathecal contrast agent
    • Sovak M, Ranganathan R, Speck U (1982) Nonionic dimer: development and initial testing of an intrathecal contrast agent. Radiology 142: 115-118.
    • (1982) Radiology , vol.142 , pp. 115-118
    • Sovak, M.1    Ranganathan, R.2    Speck, U.3
  • 23
    • 0025719705 scopus 로고
    • Safety and tolerability of iodixanol. A dimeric, nonionic contrast medium: an emphasis on European clinical phases I and II
    • Bolstad B, Borch KW, Grynne BH, Lundby B, Nossen JO, Kloster YF et al (1991) Safety and tolerability of iodixanol. A dimeric, nonionic contrast medium: an emphasis on European clinical phases I and II. Invest Radiol 26(Suppl 1): S201-204.
    • (1991) Invest Radiol , vol.26 , Issue.SUPPL. 1
    • Bolstad, B.1    Borch, K.W.2    Grynne, B.H.3    Lundby, B.4    Nossen, J.O.5    Kloster, Y.F.6
  • 24
    • 84874935184 scopus 로고    scopus 로고
    • The effect of iodinated contrast agent properties on renal kinetics and oxygenation
    • Lenhard DC, Frisk AL, Lengsfeld P, Pietsch H, Jost G (2013) The effect of iodinated contrast agent properties on renal kinetics and oxygenation. Invest Radiol 48: 175-182.
    • (2013) Invest Radiol , vol.48 , pp. 175-182
    • Lenhard, D.C.1    Frisk, A.L.2    Lengsfeld, P.3    Pietsch, H.4    Jost, G.5
  • 25
    • 84889600647 scopus 로고    scopus 로고
    • SmPC texts of the ICMs via the College ter Beoordeling van Geneesmiddelen (Medicines Evaluation Board) in The Netherlands Last accessed 24/08/2013: Amidotrizoic acid (Urografin); Iobitridol (Xenetix); Iodixanol (Visipaque); Iohexol (Omnipaque); Iomeprol (Iomeron); Iopromide (Ultravist); Ioversol (Optiray); Ioxaglate (Hexabrix); Ioxitalaminic acid (Telebrix)
    • SmPC texts of the ICMs via the College ter Beoordeling van Geneesmiddelen (Medicines Evaluation Board) in The Netherlands http://www. cbg-meb. nl/cbg/nl Last accessed 24/08/2013: Amidotrizoic acid (Urografin); Iobitridol (Xenetix); Iodixanol (Visipaque); Iohexol (Omnipaque); Iomeprol (Iomeron); Iopromide (Ultravist); Ioversol (Optiray); Ioxaglate (Hexabrix); Ioxitalaminic acid (Telebrix).
  • 26
    • 84889594237 scopus 로고    scopus 로고
    • European Society of Urogenital Radiology contrast media Safety Committee guidelines. Accesible at Last accessed 24/08/2013
    • European Society of Urogenital Radiology contrast media Safety Committee guidelines. Accesible at: http://www. esur. org/guidelines/ Last accessed 24/08/2013.
  • 27
    • 0029640011 scopus 로고
    • Hypoxia of the renal medulla-its implications for disease
    • Brezis M, Rosen S (1995) Hypoxia of the renal medulla-its implications for disease. N Engl J Med 332: 647-655.
    • (1995) N Engl J Med , vol.332 , pp. 647-655
    • Brezis, M.1    Rosen, S.2
  • 29
    • 38749112993 scopus 로고    scopus 로고
    • Renal parenchymal hypoxia, hypoxia adaptation and the pathogenesis of radiocontrast nephropathy
    • Heyman SN, Rosen S, Rosenberger C (2008) Renal parenchymal hypoxia, hypoxia adaptation and the pathogenesis of radiocontrast nephropathy. Clin J Am Soc Nephrol 3: 288-296.
    • (2008) Clin J Am Soc Nephrol , vol.3 , pp. 288-296
    • Heyman, S.N.1    Rosen, S.2    Rosenberger, C.3
  • 30
    • 18844375627 scopus 로고    scopus 로고
    • Contrast medium-induced nephrotoxicity; Which pathway?
    • Katzberg RW (2005) Contrast medium-induced nephrotoxicity; Which pathway? Radiology 235: 752-755.
    • (2005) Radiology , vol.235 , pp. 752-755
    • Katzberg, R.W.1
  • 31
    • 0032700452 scopus 로고    scopus 로고
    • Pathophysioloy of radiocontrast nephropathy
    • Heyman SN, Reichman J, Brezis M (1999) Pathophysioloy of radiocontrast nephropathy. Invest Radiol 34: 685-691.
    • (1999) Invest Radiol , vol.34 , pp. 685-691
    • Heyman, S.N.1    Reichman, J.2    Brezis, M.3
  • 32
    • 24944514021 scopus 로고    scopus 로고
    • Pathophysiology of contrast medium-induced nephropathy
    • Persson PB, Hansell P, Liss P (2005) Pathophysiology of contrast medium-induced nephropathy. Kidney International 68: 14-22.
    • (2005) Kidney International , vol.68 , pp. 14-22
    • Persson, P.B.1    Hansell, P.2    Liss, P.3
  • 33
    • 14944360223 scopus 로고    scopus 로고
    • Regional alterations in renal hemodynamcs and oxygenation: a role in contrast medium-induced nephropathy
    • Heyman SN, Rosenberger C, Rosen S (2005) Regional alterations in renal hemodynamcs and oxygenation: a role in contrast medium-induced nephropathy. Nephrol Dial Transplant 20(Suppl 1): i6-i11.
    • (2005) Nephrol Dial Transplant , vol.20 , Issue.SUPPL. 1
    • Heyman, S.N.1    Rosenberger, C.2    Rosen, S.3
  • 34
    • 67049171046 scopus 로고    scopus 로고
    • Iodixanol, constriction of medullary descending vasa recta, and risk for contrast medium-induced nephropathy
    • Sendeski M, Patzak A, Pallone T, Cao C, Persson AE, Persson PB (2009) Iodixanol, constriction of medullary descending vasa recta, and risk for contrast medium-induced nephropathy. Radiology 251: 697-704.
    • (2009) Radiology , vol.251 , pp. 697-704
    • Sendeski, M.1    Patzak, A.2    Pallone, T.3    Cao, C.4    Persson, A.E.5    Persson, P.B.6
  • 35
    • 84870004752 scopus 로고    scopus 로고
    • Iodinated contrast media differentially affect afferent and efferent arteriolar tone and reactivity in mice: A possible explanation for reduced glomerular filtration rate
    • Liu ZZ, Viegas VU, Perlewitx A, Lai EY, Persson PB, Patzak A et al (2012) Iodinated contrast media differentially affect afferent and efferent arteriolar tone and reactivity in mice: A possible explanation for reduced glomerular filtration rate. Radiology 265: 762-771.
    • (2012) Radiology , vol.265 , pp. 762-771
    • Liu, Z.Z.1    Viegas, V.U.2    Perlewitx, A.3    Lai, E.Y.4    Persson, P.B.5    Patzak, A.6
  • 36
    • 77949867992 scopus 로고    scopus 로고
    • Reactive oxygen species and the pathogenesis of radiocontrast-induced nephropathy
    • Heyman SN, Rosen S, Khamaisi M, Idee JM, Rosenberger C (2010) Reactive oxygen species and the pathogenesis of radiocontrast-induced nephropathy. Invest Radiol 45: 188-195.
    • (2010) Invest Radiol , vol.45 , pp. 188-195
    • Heyman, S.N.1    Rosen, S.2    Khamaisi, M.3    Idee, J.M.4    Rosenberger, C.5
  • 37
    • 1342281090 scopus 로고    scopus 로고
    • The cytotoxicity of iodinated radiocontrast agents on renal cells in vitro
    • Haller C, Hizoh I (2004) The cytotoxicity of iodinated radiocontrast agents on renal cells in vitro. Invest Radiol 39: 149-154.
    • (2004) Invest Radiol , vol.39 , pp. 149-154
    • Haller, C.1    Hizoh, I.2
  • 38
    • 84889582875 scopus 로고    scopus 로고
    • ACR manual on contrast media. Version 9 Accessible at Last accessed 24/08/2013
    • ACR manual on contrast media. Version 9 Accessible at: http://www. acr. org/~/media/ACR/Documents/PDF/QualitySafety/Resources/Contrast%20Manual/2013_Contrast_Media. pdf Last accessed 24/08/2013.
  • 39
    • 38749139299 scopus 로고    scopus 로고
    • N-Acetylcysteine in the prevention of contrast-induced nephropathy
    • Fishbane S (2008) N-Acetylcysteine in the prevention of contrast-induced nephropathy. Clin J Am Soc Nephrol 3: 281-287.
    • (2008) Clin J Am Soc Nephrol , vol.3 , pp. 281-287
    • Fishbane, S.1
  • 40
    • 69649092592 scopus 로고    scopus 로고
    • Prevention of contrast-induced nephropathy: An overview
    • Ellis JH, Cohan RH (2009) Prevention of contrast-induced nephropathy: An overview. Radiol Clin N Am 47: 801-811.
    • (2009) Radiol Clin N Am , vol.47 , pp. 801-811
    • Ellis, J.H.1    Cohan, R.H.2
  • 41
    • 2442590642 scopus 로고    scopus 로고
    • Prevention of contrast-induced nephropathy with sodium bicarbonate. A randomized controlled trial
    • Merten GJ, Burgess PW, Gray LV, Holleman JH, Roush TS, Kowalchuk GJ et al (2004) Prevention of contrast-induced nephropathy with sodium bicarbonate. A randomized controlled trial. JAMA 291: 2328-2334.
    • (2004) Jama , vol.291 , pp. 2328-2334
    • Merten, G.J.1    Burgess, P.W.2    Gray, L.V.3    Holleman, J.H.4    Roush, T.S.5    Kowalchuk, G.J.6
  • 42
    • 33947512067 scopus 로고    scopus 로고
    • The reno-protective effect of hydration with sodium bicarbonate plus N-acetylcysteine in patients undergoing emergency percutaneous coronary intervention: The RENO study
    • Recio-Mayoral A, Chaparro M, Prado B, Cozar R, Mendez I, Banerjee D et al (2007) The reno-protective effect of hydration with sodium bicarbonate plus N-acetylcysteine in patients undergoing emergency percutaneous coronary intervention: The RENO study. J Am Coll Cardiol 49: 1283-1288.
    • (2007) J Am Coll Cardiol , vol.49 , pp. 1283-1288
    • Recio-Mayoral, A.1    Chaparro, M.2    Prado, B.3    Cozar, R.4    Mendez, I.5    Banerjee, D.6
  • 43
    • 67649989950 scopus 로고    scopus 로고
    • A comparison of sodium bicarbonate infusion versus normal saline infusion and its combination with oral acetezolamide for prevention of contrast-induced nephropathy: A randomized, double-blind trial
    • Pakfetrat M, Nikoo MH, Malekmakan L, Tabnadeh M, Roozbeh J, Nasab MH et al (2009) A comparison of sodium bicarbonate infusion versus normal saline infusion and its combination with oral acetezolamide for prevention of contrast-induced nephropathy: A randomized, double-blind trial. Int Urol Nephrol 41: 629-634.
    • (2009) Int Urol Nephrol , vol.41 , pp. 629-634
    • Pakfetrat, M.1    Nikoo, M.H.2    Malekmakan, L.3    Tabnadeh, M.4    Roozbeh, J.5    Nasab, M.H.6
  • 44
    • 70349580111 scopus 로고    scopus 로고
    • Sodium bicarbonate plus isotonic saline versus saline for prevention of contrast-induced nephropathy in patients undergoing coronary angiography: A randomized controlled trial
    • Vasheghani-Farahani A, Sadigh G, Kassaian SE, Khatami SM, Fotouhi A, Razavi SA et al (2009) Sodium bicarbonate plus isotonic saline versus saline for prevention of contrast-induced nephropathy in patients undergoing coronary angiography: A randomized controlled trial. Am J Kidney Dis 54: 610-618.
    • (2009) Am J Kidney Dis , vol.54 , pp. 610-618
    • Vasheghani-Farahani, A.1    Sadigh, G.2    Kassaian, S.E.3    Khatami, S.M.4    Fotouhi, A.5    Razavi, S.A.6
  • 45
    • 33947716173 scopus 로고    scopus 로고
    • Renal insufficiency following contrast media administration trial (REMEDIAL). A randomized comparison of 3 preventive strategies
    • Briguori C, Airdoldi F, D'Andrea D, Bonizzoni E, Morici N, Focaciio A et al (2007) Renal insufficiency following contrast media administration trial (REMEDIAL). A randomized comparison of 3 preventive strategies. Circulation 115: 1211-1217.
    • (2007) Circulation , vol.115 , pp. 1211-1217
    • Briguori, C.1    Airdoldi, F.2    D'Andrea, D.3    Bonizzoni, E.4    Morici, N.5    Focaciio, A.6
  • 46
    • 34547947413 scopus 로고    scopus 로고
    • Comparison of usefulness of sodium bicarbonate versus sodium chloride to prevent contrast-induced nephropathy in patients undergoing an emergent coronary procedure
    • Masuda M, Yamada T, Mine T, Morita T, Tamaki S, Tsukamoto Y et al (2007) Comparison of usefulness of sodium bicarbonate versus sodium chloride to prevent contrast-induced nephropathy in patients undergoing an emergent coronary procedure. Am J Cardiol 100: 781-786.
    • (2007) Am J Cardiol , vol.100 , pp. 781-786
    • Masuda, M.1    Yamada, T.2    Mine, T.3    Morita, T.4    Tamaki, S.5    Tsukamoto, Y.6
  • 47
    • 48849097250 scopus 로고    scopus 로고
    • Sodium bicarbonate versus saline for the prevention of contrast-induced nephropathy in patients with renal dysfunction undergoing coronary angiography or intervention
    • Maioli M, Toso A, Leoncini M, Gallopin M, Tedeschi D, Micheletti C et al (2008) Sodium bicarbonate versus saline for the prevention of contrast-induced nephropathy in patients with renal dysfunction undergoing coronary angiography or intervention. J Am Coll Cardiol 52: 599-604.
    • (2008) J Am Coll Cardiol , vol.52 , pp. 599-604
    • Maioli, M.1    Toso, A.2    Leoncini, M.3    Gallopin, M.4    Tedeschi, D.5    Micheletti, C.6
  • 48
    • 56649093581 scopus 로고    scopus 로고
    • Renal insufficiency following radiocontrast exposure trial (REINFORCE): A randomized comparison of sodium bicarbonate versus sodium chloride hydration for the prevention of contrast-induced nephropathy
    • Adolph E, Holdt-Lehmann B, Chatterjee T, Paschka S, Prott A, Schneider H et al (2008) Renal insufficiency following radiocontrast exposure trial (REINFORCE): A randomized comparison of sodium bicarbonate versus sodium chloride hydration for the prevention of contrast-induced nephropathy. Coron Artery Dis 19: 413-419.
    • (2008) Coron Artery Dis , vol.19 , pp. 413-419
    • Adolph, E.1    Holdt-Lehmann, B.2    Chatterjee, T.3    Paschka, S.4    Prott, A.5    Schneider, H.6
  • 49
    • 34547944556 scopus 로고    scopus 로고
    • Sodium bicarbonate, N-acetylcysteine, and saline for prevention of radiocontrast-induced nephropathy. A comparison of 3 regimes for protecting contrast-induced nephropathy in patients undergoing coronary procedures. A single-center prospective controlled trial
    • Ozcan EE, Guneri S, Akdeniz B, Akyildiz IZ, Senaslan O, Baris N et al (2007) Sodium bicarbonate, N-acetylcysteine, and saline for prevention of radiocontrast-induced nephropathy. A comparison of 3 regimes for protecting contrast-induced nephropathy in patients undergoing coronary procedures. A single-center prospective controlled trial. Am Heart J 154: 539-544.
    • (2007) Am Heart J , vol.154 , pp. 539-544
    • Ozcan, E.E.1    Guneri, S.2    Akdeniz, B.3    Akyildiz, I.Z.4    Senaslan, O.5    Baris, N.6
  • 50
    • 50949083026 scopus 로고    scopus 로고
    • Sodium bicarbonate vs sodium chloride for the prevention of contrast medium-induced nephropathy in patients undergoing coronary angiography. A randomized trial
    • Brar SJ, Shen AYJ, Jorgensen MB, Kotlewski A, Aharonian VJ, Desai N et al (2008) Sodium bicarbonate vs sodium chloride for the prevention of contrast medium-induced nephropathy in patients undergoing coronary angiography. A randomized trial. JAMA 300: 1038-1046.
    • (2008) Jama , vol.300 , pp. 1038-1046
    • Brar, S.J.1    Shen, A.Y.J.2    Jorgensen, M.B.3    Kotlewski, A.4    Aharonian, V.J.5    Desai, N.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.