Bicyclic peptide inhibitor of urokinase-type plasminogen activator: Mode of action

ChemBioChem

Volumn 14, Issue 16, 2013, Pages 2179-2188

  Roodbeen, Renée ^a,b   Paaske, Berit ^a,c   Jiang, Longguang ^a,d   Jensen, Jan K ^a   Christensen, Anni ^a   Nielsen, Jakob T ^a,c   Huang, Mingdong ^a,d   Mulder, Frans A A ^c   Nielsen, Niels Chr ^a,c   Andreasen, Peter A ^a   Jensen, Knud J ^a,b  

^a AARHUS UNIVERSITY   (Denmark)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

^c AARHUS UNIVERSITY   (Denmark)

^d FUJIAN INSTITUTE OF RESEARCH ON THE STRUCTURE OF MATTER   (China)

Author keywords

Cancer; Isothermal titration calorimetry; NMR spectroscopy; Peptide protease interactions; X ray structures

Indexed keywords

PLASMINOGEN ACTIVATOR INHIBITOR; UROKINASE;

ARTICLE; CRYSTAL STRUCTURE; DRUG MECHANISM; ISOTHERMAL TITRATION CALORIMETRY; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; THERMODYNAMICS;

CANCER; ISOTHERMAL TITRATION CALORIMETRY; NMR SPECTROSCOPY; PEPTIDE-PROTEASE INTERACTIONS; X-RAY STRUCTURES;

AMINO ACID SEQUENCE; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; DRUG DESIGN; HUMANS; KINETICS; PEPTIDES, CYCLIC; PROTEASE INHIBITORS; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; UROKINASE-TYPE PLASMINOGEN ACTIVATOR;

EID: 84889571687     PISSN: 14394227     EISSN: 14397633     Source Type: Journal    
DOI: 10.1002/cbic.201300335     Document Type: Article

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