메뉴 건너뛰기




Volumn , Issue , 2007, Pages 315-326

Management of Hyponatremia in Cirrhosis

Author keywords

Cirrhosis; Diuretics; Epidemiology; Hyponatremia; Neurohormonal systems

Indexed keywords


EID: 84889423727     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9780470987476.ch26     Document Type: Chapter
Times cited : (5)

References (65)
  • 1
    • 0017129032 scopus 로고
    • Prognostic value of spontaneous hyponatremia in cirrhosis with ascites
    • Arroyo V, Rodés J, Gutiérrez-Lizarraga MA et al. Prognostic value of spontaneous hyponatremia in cirrhosis with ascites. Am J Dig Dis 1976; 21:249-56.
    • (1976) Am J Dig Dis , vol.21 , pp. 249-256
    • Arroyo, V.1    Rodés, J.2    Gutiérrez-Lizarraga, M.A.3
  • 2
    • 0037060045 scopus 로고    scopus 로고
    • Dilutional hyponatremia in patients with cirrhosis and ascites
    • Porcel A, Diaz F, Rendon P et al. Dilutional hyponatremia in patients with cirrhosis and ascites. Arch Intern Med 2002; 162:323-8.
    • (2002) Arch Intern Med , vol.162 , pp. 323-328
    • Porcel, A.1    Diaz, F.2    Rendon, P.3
  • 3
    • 0019350474 scopus 로고
    • Plasma renin activity and urinary sodium excretion as prognostic indicators in nonazotemic cirrhosis with ascites
    • Arroyo V, Bosch J, Gaya-Beltran J et al. Plasma renin activity and urinary sodium excretion as prognostic indicators in nonazotemic cirrhosis with ascites. Ann Intern Med 1981; 94:198-201.
    • (1981) Ann Intern Med , vol.94 , pp. 198-201
    • Arroyo, V.1    Bosch, J.2    Gaya-Beltran, J.3
  • 4
    • 0035137832 scopus 로고    scopus 로고
    • A prognostic model for predicting survival in cirrhosis with ascites
    • Fernández-Esparrach G, Sanchez-Fueyo A, Ginès P et al. A prognostic model for predicting survival in cirrhosis with ascites. J Hepatol 2001; 34:46-52.
    • (2001) J Hepatol , vol.34 , pp. 46-52
    • Fernández-Esparrach, G.1    Sanchez-Fueyo, A.2    Ginès, P.3
  • 5
    • 33845608967 scopus 로고    scopus 로고
    • Liver disease and the kidney
    • Schrier R, ed, 7th edn. Philadelphia: Lippincott Williams & Wilkins
    • Ginès P, Cárdenas A, Schrier R. Liver disease and the kidney. In: Schrier R, ed. Diseases of the Kidney and Urinary Tract, 7th edn. Philadelphia: Lippincott Williams & Wilkins, 2001; 2167-203.
    • (2001) Diseases of the Kidney and Urinary Tract , pp. 2167-2203
    • Ginès, P.1    Cárdenas, A.2    Schrier, R.3
  • 6
    • 0022651395 scopus 로고
    • Hyponatremia, convulsions, respiratory arrest, and permanent brain damage after elective surgery in healthy women
    • Arieff AI. Hyponatremia, convulsions, respiratory arrest, and permanent brain damage after elective surgery in healthy women. N Engl J Med 1986; 314:1529-35.
    • (1986) N Engl J Med , vol.314 , pp. 1529-1535
    • Arieff, A.I.1
  • 7
    • 0028855225 scopus 로고
    • Pulmonary complications of hyponatremic encephalopathy. Noncardiogenic pulmonary edema and hypercapnic respiratory failure
    • Ayus JC, Arieff AI. Pulmonary complications of hyponatremic encephalopathy. Noncardiogenic pulmonary edema and hypercapnic respiratory failure. Chest 1995; 107:517-21.
    • (1995) Chest , vol.107 , pp. 517-521
    • Ayus, J.C.1    Arieff, A.I.2
  • 8
    • 0031046793 scopus 로고    scopus 로고
    • Epidemiology, pathophysiology, and management of hyponatremic encephalopathy
    • Fraser C, Arieff AI. Epidemiology, pathophysiology, and management of hyponatremic encephalopathy. Am J Med 1997; 102:67-77.
    • (1997) Am J Med , vol.102 , pp. 67-77
    • Fraser, C.1    Arieff, A.I.2
  • 9
    • 0028558703 scopus 로고
    • Molecular characterization of an aquaporin cDNA from brain: candidate osmoreceptor and regulator of water balance
    • Jung JS, Bhat RV, Preston GM et al. Molecular characterization of an aquaporin cDNA from brain: candidate osmoreceptor and regulator of water balance. Proc Natl Acad Sci USA 1994; 91:13052-6.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 13052-13056
    • Jung, J.S.1    Bhat, R.V.2    Preston, G.M.3
  • 10
    • 11244347213 scopus 로고    scopus 로고
    • Pathophysiology of water metabolism
    • Brenner BM, ed, 7th edn. Amsterdam: Elsevier
    • Berl T, Verbalis J. Pathophysiology of water metabolism. In: Brenner BM, ed. Brenner & Rector's The Kidney, 7th edn. Amsterdam: Elsevier, 2004; 857-920.
    • (2004) Brenner & Rector's The Kidney , pp. 857-920
    • Berl, T.1    Verbalis, J.2
  • 11
    • 0027499670 scopus 로고
    • Control of brain volume during hyperosmolar and hypoosmolar conditions
    • Gullans SR, Verbalis JG. Control of brain volume during hyperosmolar and hypoosmolar conditions. Annu Rev Med 1993; 44:289-301.
    • (1993) Annu Rev Med , vol.44 , pp. 289-301
    • Gullans, S.R.1    Verbalis, J.G.2
  • 12
    • 0023248603 scopus 로고
    • Volume regulatory loss of Na+, Cl-, and K+ from rat brain during acute hyponatremia
    • Melton JE, Patlak CS, Pettigrew CD, Cserr HF. Volume regulatory loss of Na+, Cl-, and K+ from rat brain during acute hyponatremia. Am J Physiol 1987; 252 (4 Pt 2):F661-9.
    • (1987) Am J Physiol , vol.252 , Issue.4 PT 2
    • Melton, J.E.1    Patlak, C.S.2    Pettigrew, C.D.3    Cserr, H.F.4
  • 13
    • 0026342015 scopus 로고
    • Hyponatremia causes large sustained reductions in brain content of multiple organic osmolytes in rats
    • Verbalis JG, Gullans SR. Hyponatremia causes large sustained reductions in brain content of multiple organic osmolytes in rats. Brain Res 1991; 567:274-82.
    • (1991) Brain Res , vol.567 , pp. 274-282
    • Verbalis, J.G.1    Gullans, S.R.2
  • 14
    • 0027478923 scopus 로고
    • Rapid correction of hyponatremia produces differential effects on brain osmolyte and electrolyte reaccumulation in rats
    • Verbalis JG, Gullans SR. Rapid correction of hyponatremia produces differential effects on brain osmolyte and electrolyte reaccumulation in rats. Brain Res 1993; 606:19-27.
    • (1993) Brain Res , vol.606 , pp. 19-27
    • Verbalis, J.G.1    Gullans, S.R.2
  • 15
    • 0025772319 scopus 로고
    • Study of brain electrolytes and organic osmolytes during correction of chronic hyponatremia: implications for the pathogenesis of central pontine myelinolysis
    • Lien YH, Shapiro JI, Chan L. Study of brain electrolytes and organic osmolytes during correction of chronic hyponatremia: implications for the pathogenesis of central pontine myelinolysis. J Clin Invest 1991; 88:303-9.
    • (1991) J Clin Invest , vol.88 , pp. 303-309
    • Lien, Y.H.1    Shapiro, J.I.2    Chan, L.3
  • 16
    • 0022633817 scopus 로고
    • Osmotic demyelination syndrome following correction of hyponatremia
    • Sterns RH, Riggs JE, Schochet SS Jr. Osmotic demyelination syndrome following correction of hyponatremia. N Engl J Med 1986; 314:1535-42.
    • (1986) N Engl J Med , vol.314 , pp. 1535-1542
    • Sterns, R.H.1    Riggs, J.E.2    Schochet Jr, S.S.3
  • 17
    • 0041669381 scopus 로고    scopus 로고
    • Pathogenesis of hepatic encephalopathy: new insights from neuroimaging and molecular studies
    • Butterworth RF. Pathogenesis of hepatic encephalopathy: new insights from neuroimaging and molecular studies. J Hepatol 2003; 39:278-85.
    • (2003) J Hepatol , vol.39 , pp. 278-285
    • Butterworth, R.F.1
  • 18
    • 0030460455 scopus 로고    scopus 로고
    • The application of magnetic resonance spectroscopy to the study of hepatic encephalopathy
    • Seery JP, Taylor-Robinson SD. The application of magnetic resonance spectroscopy to the study of hepatic encephalopathy. J Hepatol 1996; 25:988-98.
    • (1996) J Hepatol , vol.25 , pp. 988-998
    • Seery, J.P.1    Taylor-Robinson, S.D.2
  • 19
    • 0036988606 scopus 로고    scopus 로고
    • Pathophysiology of hepatic encephalopathy: a new look at ammonia
    • Butterworth RF. Pathophysiology of hepatic encephalopathy: a new look at ammonia. Metab Brain Dis 2002; 17:221-7.
    • (2002) Metab Brain Dis , vol.17 , pp. 221-227
    • Butterworth, R.F.1
  • 20
    • 0028037077 scopus 로고
    • Proton magnetic resonance spectroscopy studies on human brain myoinositol in hypo-osmolarity and hepatic encephalopathy
    • Haussinger D, Laubenberger J, vom Dahl S et al. Proton magnetic resonance spectroscopy studies on human brain myoinositol in hypo-osmolarity and hepatic encephalopathy. Gastroenterology 1994; 107:1475-80.
    • (1994) Gastroenterology , vol.107 , pp. 1475-1480
    • Haussinger, D.1    Laubenberger, J.2    Vom Dahl, S.3
  • 21
    • 2542586278 scopus 로고    scopus 로고
    • Effect of dilutional hyponatremia on brain organic osmolytes and water content in patients with cirrhosis
    • Restuccia T, Gómez-Ansón B, Guevera M et al. Effect of dilutional hyponatremia on brain organic osmolytes and water content in patients with cirrhosis. Hepatology 2004; 39:1613-22.
    • (2004) Hepatology , vol.39 , pp. 1613-1622
    • Restuccia, T.1    Gómez-Ansón, B.2    Guevera, M.3
  • 22
    • 0032190949 scopus 로고    scopus 로고
    • Chronic hyponatremia exacerbates ammonia-induced brain edema in rats after portacaval anastomosis
    • Córdoba J, Gottstein J, Blei AT. Chronic hyponatremia exacerbates ammonia-induced brain edema in rats after portacaval anastomosis. J Hepatol 1998; 29:589-94.
    • (1998) J Hepatol , vol.29 , pp. 589-594
    • Córdoba, J.1    Gottstein, J.2    Blei, A.T.3
  • 23
    • 0031783252 scopus 로고    scopus 로고
    • Hyponatremia in cirrhosis: from pathogenesis to treatment
    • Ginès P, Berl T, Bernardi M et al. Hyponatremia in cirrhosis: from pathogenesis to treatment. Hepatology 1998; 28:851-64.
    • (1998) Hepatology , vol.28 , pp. 851-864
    • Ginès, P.1    Berl, T.2    Bernardi, M.3
  • 24
    • 0028092771 scopus 로고
    • Predictive factors of early postoperative graft function in human liver transplantation
    • González FX, Rimola A, Grande L et al. Predictive factors of early postoperative graft function in human liver transplantation. Hepatology 1994; 20:565-73.
    • (1994) Hepatology , vol.20 , pp. 565-573
    • González, F.X.1    Rimola, A.2    Grande, L.3
  • 26
    • 0024803898 scopus 로고
    • Pontine and extrapontine myelinosis following liver transplantation. Relationship to serum sodium
    • Wszolek ZK, McComb RD, Pfeiffer RF et al. Pontine and extrapontine myelinosis following liver transplantation. Relationship to serum sodium. Transplantation 1989; 48:1006-12.
    • (1989) Transplantation , vol.48 , pp. 1006-1012
    • Wszolek, Z.K.1    McComb, R.D.2    Pfeiffer, R.F.3
  • 27
    • 0031808961 scopus 로고    scopus 로고
    • Liver transplantation in hyponatremic patients with the emphasis on central pontine myelinolysis
    • Abbasoglu O, Goldstein RM, Vodapally MS et al. Liver transplantation in hyponatremic patients with the emphasis on central pontine myelinolysis. Clin Transplant 1998; 12:263-9.
    • (1998) Clin Transplant , vol.12 , pp. 263-269
    • Abbasoglu, O.1    Goldstein, R.M.2    Vodapally, M.S.3
  • 28
    • 0033975171 scopus 로고    scopus 로고
    • Central nervous system complications in liver transplant recipients-incidence, timing, and long-term follow-up
    • Bronster DJ, Emre S, Boccagni P, Sheiner PA, Schwartz ME, Miller CM. Central nervous system complications in liver transplant recipients-incidence, timing, and long-term follow-up. Clin Transplant 2000; 14:1-7.
    • (2000) Clin Transplant , vol.14 , pp. 1-7
    • Bronster, D.J.1    Emre, S.2    Boccagni, P.3    Sheiner, P.A.4    Schwartz, M.E.5    Miller, C.M.6
  • 29
    • 0035034634 scopus 로고    scopus 로고
    • Correction of hyponatremia
    • Gross P. Correction of hyponatremia. Semin Nephrol 2001; 21:269-72.
    • (2001) Semin Nephrol , vol.21 , pp. 269-272
    • Gross, P.1
  • 30
    • 0344806948 scopus 로고    scopus 로고
    • Therapy of hyponatremia in cirrhosis with a vasopressin receptor antagonist: a randomized double-blind multicenter trial
    • VPA Study Group
    • Gerbes AL, Gulberg V, Ginès P et al.; VPA Study Group. Therapy of hyponatremia in cirrhosis with a vasopressin receptor antagonist: a randomized double-blind multicenter trial. Gastroenterology 2003; 124:933-9.
    • (2003) Gastroenterology , vol.124 , pp. 933-939
    • Gerbes, A.L.1    Gulberg, V.2    Ginès, P.3
  • 31
    • 14644432570 scopus 로고    scopus 로고
    • Pathogenesis and treatment of dilutional hyponatremia in cirrhosis
    • Arroyo V, Forns X, Garcia-Pagan JC, Rodés J, eds, Barcelona: Ars Medica
    • Cárdenas A, Ginès P. Pathogenesis and treatment of dilutional hyponatremia in cirrhosis. In: Arroyo V, Forns X, Garcia-Pagan JC, Rodés J, eds. Progress in the Treatment of Liver Diseases. Barcelona: Ars Medica, 2003; 31-42.
    • (2003) Progress in the Treatment of Liver Diseases , pp. 31-42
    • Cárdenas, A.1    Ginès, P.2
  • 32
    • 0021132354 scopus 로고
    • Evidence that renal prostaglandins are involved in renal water metabolism in cirrhosis
    • Perez-Ayuso RM, Arroyo V, Camps J et al. Evidence that renal prostaglandins are involved in renal water metabolism in cirrhosis. Kidney Int 1984; 26:72-80.
    • (1984) Kidney Int , vol.26 , pp. 72-80
    • Perez-Ayuso, R.M.1    Arroyo, V.2    Camps, J.3
  • 33
    • 0023907437 scopus 로고
    • Randomized comparative study of therapeutic paracentesis with and without intravenous albumin in cirrhosis
    • Ginès P, Titó L, Arroyo V et al. Randomized comparative study of therapeutic paracentesis with and without intravenous albumin in cirrhosis. Gastroenterology 1988; 94:1493-502.
    • (1988) Gastroenterology , vol.94 , pp. 1493-1502
    • Ginès, P.1    Titó, L.2    Arroyo, V.3
  • 35
    • 0021322304 scopus 로고
    • Effect of demeclocycline on renal function and urinary prostaglandin E2 and kallikrein in hyponatremic cirrhotics
    • Pérez-Ayuso RM, Arroyo V, Camps J et al. Effect of demeclocycline on renal function and urinary prostaglandin E2 and kallikrein in hyponatremic cirrhotics. Nephron 1984; 36:30-3.
    • (1984) Nephron , vol.36 , pp. 30-33
    • Pérez-Ayuso, R.M.1    Arroyo, V.2    Camps, J.3
  • 37
    • 0023030639 scopus 로고
    • Treatment of hyponatremic cirrhosis with ascites resistant to urea
    • Decaux G, Mols P, Cauchie P, Flamion B, Delwiche F. Treatment of hyponatremic cirrhosis with ascites resistant to urea. Nephron 1986; 44:337-43.
    • (1986) Nephron , vol.44 , pp. 337-343
    • Decaux, G.1    Mols, P.2    Cauchie, P.3    Flamion, B.4    Delwiche, F.5
  • 38
    • 0021051888 scopus 로고
    • Further study of kappa opioids in increased urination
    • Leander JD. Further study of kappa opioids in increased urination. J Pharmacol Exp Ther 1983; 227:35-41.
    • (1983) J Pharmacol Exp Ther , vol.227 , pp. 35-41
    • Leander, J.D.1
  • 39
    • 0030433056 scopus 로고    scopus 로고
    • Systemic and regional hemodynamic and biological effects of a new kappa-opioid agonist, niravoline, in healthy volunteers
    • Bellissant E, Denolle T, Sinnassamy P et al. Systemic and regional hemodynamic and biological effects of a new kappa-opioid agonist, niravoline, in healthy volunteers. J Pharmacol Exp Ther 1996; 278:232-42.
    • (1996) J Pharmacol Exp Ther , vol.278 , pp. 232-242
    • Bellissant, E.1    Denolle, T.2    Sinnassamy, P.3
  • 40
    • 0024578653 scopus 로고
    • Mechanism of diuretic action of U-62,066E, a kappa opioid receptor agonist
    • Yamada K, Imai M, Yoshida S. Mechanism of diuretic action of U-62,066E, a kappa opioid receptor agonist. Eur J Pharmacol 1989; 160:229-37.
    • (1989) Eur J Pharmacol , vol.160 , pp. 229-237
    • Yamada, K.1    Imai, M.2    Yoshida, S.3
  • 42
    • 0029024371 scopus 로고
    • Aquaretic effect of the κ-opioid agonist RU 51599 in cirrhotic rats with ascites and water retention
    • Bosch-Marcé M, Jiménez W, Angeli P et al. Aquaretic effect of the κ-opioid agonist RU 51599 in cirrhotic rats with ascites and water retention. Gastroenterology 1995; 109:217-23.
    • (1995) Gastroenterology , vol.109 , pp. 217-223
    • Bosch-Marcé, M.1    Jiménez, W.2    Angeli, P.3
  • 43
    • 0029799582 scopus 로고    scopus 로고
    • Renal and haemodynamic responses to a novel kappa opioid receptor agonist, niravoline (RU 51,599), in rats with cirrhosis
    • Moreau R, Cailmail S, Hamon G, Lebrec D. Renal and haemodynamic responses to a novel kappa opioid receptor agonist, niravoline (RU 51,599), in rats with cirrhosis. J Gastroenterol Hepatol 1996; 11:857-63.
    • (1996) J Gastroenterol Hepatol , vol.11 , pp. 857-863
    • Moreau, R.1    Cailmail, S.2    Hamon, G.3    Lebrec, D.4
  • 44
    • 0032917959 scopus 로고    scopus 로고
    • Comparison of two aquaretic drugs (niravoline and OPC-31260) in cirrhotic rats with ascites and water retention
    • Bosch-Marcé M, Poo JL, Jiménez W et al. Comparison of two aquaretic drugs (niravoline and OPC-31260) in cirrhotic rats with ascites and water retention. J Pharmacol Exp Ther 1999; 289:194-201.
    • (1999) J Pharmacol Exp Ther , vol.289 , pp. 194-201
    • Bosch-Marcé, M.1    Poo, J.L.2    Jiménez, W.3
  • 45
    • 0033959834 scopus 로고    scopus 로고
    • Aquaretic effects of niravoline, a kappa-opioid agonist, in patients with cirrhosis
    • Gadano A, Moreau R, Pessione F et al. Aquaretic effects of niravoline, a kappa-opioid agonist, in patients with cirrhosis. J Hepatol 2000; 32:38-42.
    • (2000) J Hepatol , vol.32 , pp. 38-42
    • Gadano, A.1    Moreau, R.2    Pessione, F.3
  • 46
    • 0019433197 scopus 로고
    • Vasopressin analogs that antagonize antidiuretic responses by rats to the antidiuretic hormone
    • Sawyer WH, Pang PK, Seto J, McEnroe M, Lammec B, Manning M. Vasopressin analogs that antagonize antidiuretic responses by rats to the antidiuretic hormone. Science 1981; 212:49-51.
    • (1981) Science , vol.212 , pp. 49-51
    • Sawyer, W.H.1    Pang, P.K.2    Seto, J.3    McEnroe, M.4    Lammec, B.5    Manning, M.6
  • 47
    • 0026533435 scopus 로고
    • Characterization of a novel aquaretic agent, OPC-31260, as an orally effective, nonpeptide vasopressin V2 receptor antagonist
    • Yamamura Y, Ogawa H, Yamashita H et al. Characterization of a novel aquaretic agent, OPC-31260, as an orally effective, nonpeptide vasopressin V2 receptor antagonist. Br J Phamacol 1992; 105:787-91.
    • (1992) Br J Phamacol , vol.105 , pp. 787-791
    • Yamamura, Y.1    Ogawa, H.2    Yamashita, H.3
  • 48
    • 0035882211 scopus 로고    scopus 로고
    • Vasopressin V2 receptor antagonists
    • Wong LL, Verbalis J. Vasopressin V2 receptor antagonists. Cardiovasc Res 2001; 51:391-402.
    • (2001) Cardiovasc Res , vol.51 , pp. 391-402
    • Wong, L.L.1    Verbalis, J.2
  • 49
    • 0027174346 scopus 로고
    • Therapeutic efficacy of non-peptide ADH antagonist OPC-31260 in SIADH rats
    • Fujisawa G, Ishikawa S, Tsuboi Y, Okada K, Saito T. Therapeutic efficacy of non-peptide ADH antagonist OPC-31260 in SIADH rats. Kidney Int 1993; 44:19-23.
    • (1993) Kidney Int , vol.44 , pp. 19-23
    • Fujisawa, G.1    Ishikawa, S.2    Tsuboi, Y.3    Okada, K.4    Saito, T.5
  • 50
    • 0027143189 scopus 로고
    • Potent aquaretic agent. A novel nonpeptide selective vasopressin V2 antagonist (OPC-31260) in men
    • Ohnishi A, Orita Y, Okahara R et al. Potent aquaretic agent. A novel nonpeptide selective vasopressin V2 antagonist (OPC-31260) in men. J Clin Invest 1993; 92:2653-9.
    • (1993) J Clin Invest , vol.92 , pp. 2653-2659
    • Ohnishi, A.1    Orita, Y.2    Okahara, R.3
  • 51
    • 0028796361 scopus 로고
    • Aquaretic effect of a potent, orally active, nonpeptide V2 antagonist in men
    • Ohnishi A, Orita Y, Takagi N et al. Aquaretic effect of a potent, orally active, nonpeptide V2 antagonist in men. J Pharmacol Exp Ther 1995; 272:546-51.
    • (1995) J Pharmacol Exp Ther , vol.272 , pp. 546-551
    • Ohnishi, A.1    Orita, Y.2    Takagi, N.3
  • 52
    • 0031001022 scopus 로고    scopus 로고
    • Acute aquaresis by the nonpeptide arginine vasopressin (AVP) antagonist OPC-31260 improves hyponatremia in patients with syndrome of inappropriate secretion of antidiuretic hormone (SIADH)
    • Saito T, Ishikawa S, Abe K et al. Acute aquaresis by the nonpeptide arginine vasopressin (AVP) antagonist OPC-31260 improves hyponatremia in patients with syndrome of inappropriate secretion of antidiuretic hormone (SIADH). J Clin Endocrinol Metab 1997; 82:1054-7.
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 1054-1057
    • Saito, T.1    Ishikawa, S.2    Abe, K.3
  • 53
    • 0009689526 scopus 로고    scopus 로고
    • Characterization of SR121463A, a highly potent and selective, orally active vasopressin V2 receptor antagonist
    • Serradeil-Le Gal C, Lacour C, Valette G et al. Characterization of SR121463A, a highly potent and selective, orally active vasopressin V2 receptor antagonist. J Clin Invest 1996; 98:2729-38.
    • (1996) J Clin Invest , vol.98 , pp. 2729-2738
    • Serradeil-Le Gal, C.1    Lacour, C.2    Valette, G.3
  • 54
    • 0000849114 scopus 로고    scopus 로고
    • VPA-985: a novel non-peptide competitive vasopressin receptor antagonist for the treatment of dilutional hyponatremia
    • Abstract
    • Epstein M, Orczky G, Muralidharan G, Fruncillo R. VPA-985: a novel non-peptide competitive vasopressin receptor antagonist for the treatment of dilutional hyponatremia. J Am Soc Nephrol 1998; 9:0544 (Abstract).
    • (1998) J Am Soc Nephrol , vol.9 , pp. 0544
    • Epstein, M.1    Orczky, G.2    Muralidharan, G.3    Fruncillo, R.4
  • 55
    • 0037904417 scopus 로고    scopus 로고
    • Vasopressin V2-receptor blockade with tolvaptan in patients with chronic heart failure: results from a double-blind, randomized trial
    • Gheorghiade M, Niazi I, Ouyang J et al. Vasopressin V2-receptor blockade with tolvaptan in patients with chronic heart failure: results from a double-blind, randomized trial. Circulation 2003; 107:2690-6.
    • (2003) Circulation , vol.107 , pp. 2690-2696
    • Gheorghiade, M.1    Niazi, I.2    Ouyang, J.3
  • 56
    • 0032755612 scopus 로고    scopus 로고
    • Pharmacokinetic and pharmacodynamic effects of YM087, a combined V1/V2 vasopressin receptor antagonist in normal subjects
    • Burnier M, Fricker AF, Hayoz D, Nussberger J, Brunner HR. Pharmacokinetic and pharmacodynamic effects of YM087, a combined V1/V2 vasopressin receptor antagonist in normal subjects. Eur J Clin Pharmacol 1999; 55:633-7.
    • (1999) Eur J Clin Pharmacol , vol.55 , pp. 633-637
    • Burnier, M.1    Fricker, A.F.2    Hayoz, D.3    Nussberger, J.4    Brunner, H.R.5
  • 57
    • 0037162707 scopus 로고    scopus 로고
    • Effect of the vasopressin receptor antagonist conivaptan in rats with heart failure following myocardial infarction
    • Wada K, Tahara A, Arai Y et al. Effect of the vasopressin receptor antagonist conivaptan in rats with heart failure following myocardial infarction. Eur J Pharmacol 2002; 450:169-77.
    • (2002) Eur J Pharmacol , vol.450 , pp. 169-177
    • Wada, K.1    Tahara, A.2    Arai, Y.3
  • 58
    • 0037141763 scopus 로고    scopus 로고
    • Pharmacological characterization of YM471, a novel potent vasopressin V(1A) and V(2) receptor antagonist
    • Tsukada J, Tahara A, Tomura Y et al. Pharmacological characterization of YM471, a novel potent vasopressin V(1A) and V(2) receptor antagonist. Eur J Pharmacol 2002; 446:129-38.
    • (2002) Eur J Pharmacol , vol.446 , pp. 129-138
    • Tsukada, J.1    Tahara, A.2    Tomura, Y.3
  • 59
    • 0024434287 scopus 로고
    • Blockade of the hydroosmotic effect of vasopressin normalizes water excretion in cirrhotic rats
    • Clària J, Jiménez W, Arroyo V et al. Blockade of the hydroosmotic effect of vasopressin normalizes water excretion in cirrhotic rats. Gastroenterology 1989; 97:1294-9.
    • (1989) Gastroenterology , vol.97 , pp. 1294-1299
    • Clària, J.1    Jiménez, W.2    Arroyo, V.3
  • 60
    • 0028286789 scopus 로고
    • Therapeutic efficacy of the non-peptide AVP antagonist OPC-31260 in cirrhotic rats
    • Tsuboi Y, Ishikawa S, Fujisawa G, Okada K, Saito T. Therapeutic efficacy of the non-peptide AVP antagonist OPC-31260 in cirrhotic rats. Kidney Int 1994; 46:237-44.
    • (1994) Kidney Int , vol.46 , pp. 237-244
    • Tsuboi, Y.1    Ishikawa, S.2    Fujisawa, G.3    Okada, K.4    Saito, T.5
  • 61
    • 0033810608 scopus 로고    scopus 로고
    • Long-term aquaretic efficacy of a selective nonpeptide V(2)-vasopressin receptor antagonist, SR121463, in cirrhotic rats
    • Jiménez W, Serradeil-le-Gal C, Ros J et al. Long-term aquaretic efficacy of a selective nonpeptide V(2)-vasopressin receptor antagonist, SR121463, in cirrhotic rats. J Pharmacol Exp Ther 2000; 295:83-90.
    • (2000) J Pharmacol Exp Ther , vol.295 , pp. 83-90
    • Jiménez, W.1    Serradeil-le-Gal, C.2    Ros, J.3
  • 62
    • 0038578522 scopus 로고    scopus 로고
    • Effect of the V1a/V2-AVP receptor antagonist, conivaptan, on renal water metabolism and systemic hemodynamics in rats with cirrhosis and ascites
    • Fernández-Varo G, Ros J, Cejudo-Martin P et al. Effect of the V1a/V2-AVP receptor antagonist, conivaptan, on renal water metabolism and systemic hemodynamics in rats with cirrhosis and ascites. J Hepatol 2003; 38:755-61.
    • (2003) J Hepatol , vol.38 , pp. 755-761
    • Fernández-Varo, G.1    Ros, J.2    Cejudo-Martin, P.3
  • 63
    • 13144266671 scopus 로고    scopus 로고
    • Therapeutic and diagnostic potential of a vasopressin-2 antagonist for impaired water handling in cirrhosis
    • Inoue T, Ohnishi A, Matsuo A et al. Therapeutic and diagnostic potential of a vasopressin-2 antagonist for impaired water handling in cirrhosis. Clin Pharmacol Ther 1998; 63:561-70.
    • (1998) Clin Pharmacol Ther , vol.63 , pp. 561-570
    • Inoue, T.1    Ohnishi, A.2    Matsuo, A.3
  • 64
    • 0036828808 scopus 로고    scopus 로고
    • Pharmacodynamic effects of a nonpeptide antidiuretic hormone V2 antagonist in cirrhotic patients with ascites
    • Guyader D, Patat A, Ellis-Grosse EJ, Orczyk GP. Pharmacodynamic effects of a nonpeptide antidiuretic hormone V2 antagonist in cirrhotic patients with ascites. Hepatology 2002; 36:1197-205.
    • (2002) Hepatology , vol.36 , pp. 1197-1205
    • Guyader, D.1    Patat, A.2    Ellis-Grosse, E.J.3    Orczyk, G.P.4
  • 65
    • 0037223321 scopus 로고    scopus 로고
    • A vasopressin receptor antagonist (VPA-985) improves serum sodium concentration in patients with hyponatremia: a multicenter, randomized, placebo-controlled trial
    • Wong F, Blei AT, Blendis LM, Thuluvath PJ. A vasopressin receptor antagonist (VPA-985) improves serum sodium concentration in patients with hyponatremia: a multicenter, randomized, placebo-controlled trial. Hepatology 2003; 37:182-91.
    • (2003) Hepatology , vol.37 , pp. 182-191
    • Wong, F.1    Blei, A.T.2    Blendis, L.M.3    Thuluvath, P.J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.