Inhibition of the sur1-trpm4 channel reduces neuroinflammation and cognitive impairment in subarachnoid hemorrhage

Stroke

Volumn 44, Issue 12, 2013, Pages 3522-3528

  Tosun, Cigdem ^a   Kurland, David B ^a   Mehta, Rupal ^a   Castellani, Rudy J ^a   Dejong, Joyce L ^c   Kwon, Min Seong ^a   Woo, Seung Kyoon ^a   Gerzanich, Volodymyr ^a   Simard, J Marc ^a,b  

^a Department of Neurosurgery ^*  (United States)

^b UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^c WESTERN MICHIGAN UNIVERSITY HOMER STRYKER MD SCHOOL OF MEDICINE   (United States)

Author keywords

Cognition; Memory; Subarachnoid hemorrhage; Sulfonylurea receptor; Transient receptor potential melastatin 4

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; GLIBENCLAMIDE; IMMUNOGLOBULIN G; SULFONYLUREA RECEPTOR 1; TRANSIENT RECEPTOR POTENTIAL CHANNEL M4; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOPSY; BLOOD BRAIN BARRIER; CHROMATIN IMMUNOPRECIPITATION; COGNITIVE DEFECT; CONTROLLED STUDY; ENTORHINAL CORTEX; FLUORESCENCE RESONANCE ENERGY TRANSFER; HUMAN; HUMAN EXPERIMENT; HUMAN TISSUE; INTERNAL CAROTID ARTERY; MALE; MEMORY; NERVOUS SYSTEM INFLAMMATION; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SPATIAL LEARNING; SUBARACHNOID HEMORRHAGE; SUBARACHNOID SPACE; UPREGULATION;

COGNITION; MEMORY; SUBARACHNOID HEMORRHAGE; SULFONYLUREA RECEPTOR; TRANSIENT RECEPTOR POTENTIAL MELASTATIN 4;

ANIMALS; BRAIN; COGNITION DISORDERS; ENCEPHALITIS; GLYBURIDE; HUMANS; MAZE LEARNING; RATS; SUBARACHNOID HEMORRHAGE; SULFONYLUREA RECEPTORS; TRPM CATION CHANNELS; UP-REGULATION;

EID: 84889248163     PISSN: 00392499     EISSN: 15244628     Source Type: Journal    
DOI: 10.1161/STROKEAHA.113.002904     Document Type: Article

References (26)

1. Hanel RA, Xavier AR, Mohammad Y, Kirmani JF, Yahia AM, Qureshi AI. Outcome following intracerebral hemorrhage and subarachnoid hemorrhage. Neurol Res. 2002;24 suppl 1:S58-S62.
2. Quigley MR, Salary M. Defining survivorship after high-grade aneurysmal subarachnoid hemorrhage. Surg Neurol. 2008;69:261-265.
3. Niikawa S, Kitajima H, Ohe N, Miwa Y, Ohkuma A. Significance of acute cerebral swelling in patients with sylvian hematoma due to ruptured middle cerebral artery aneurysm, and its management. Neurol Med Chir (Tokyo). 1998;38:844-849.
4. Ma J, Huang S, Ma L, Liu Y, Li H, You C. Endothelin-receptor antagonists for aneurysmal subarachnoid hemorrhage: an updated meta-analysis of randomized controlled trials. Crit Care. 2012;16:R198.
5. Al-Khindi T, Macdonald RL, Schweizer TA. Cognitive and functional outcome after aneurysmal subarachnoid hemorrhage. Stroke. 2010;41:e519-e536.
6. Shi NQ, Ye B, Makielski JC. Function and distribution of the SUR isoforms and splice variants. J Mol Cell Cardiol. 2005;39:51-60.
7. Aittoniemi J, Fotinou C, Craig TJ, de Wet H, Proks P, Ashcroft FM. Review. SUR1: a unique ATP-binding cassette protein that functions as an ion channel regulator. Philos Trans R Soc Lond B Biol Sci. 2009;364:257-267.
8. Hollenstein K, Dawson RJ, Locher KP. Structure and mechanism of ABC transporter proteins. Curr Opin Struct Biol. 2007;17:412-418.
9. Woo SK, Kwon MS, Ivanov A, Gerzanich V, Simard JM. The sulfonylurea receptor 1 (Sur1)-transient receptor potential melastatin 4 (Trpm4) channel. J Biol Chem. 2013;288:3655-3667.
10. Simard JM, Woo SK, Schwartzbauer GT, Gerzanich V. Sulfonylurea receptor 1 in central nervous system injury: a focused review. J Cereb Blood Flow Metab. 2012;32:1699-1717.
11. Simard JM, Woo SK, Gerzanich V. Transient receptor potential melastatin 4 and cell death. Pflugers Arch. 2012;464:573-582.
12. Simard JM, Chen M, Tarasov KV, Bhatta S, Ivanova S, Melnitchenko L, et al. Newly expressed SUR1-regulated NC(Ca-ATP) channel mediates cerebral edema after ischemic stroke. Nat Med. 2006;12:433-440.
13. Simard JM, Geng Z, Woo SK, Ivanova S, Tosun C, Melnichenko L, et al. Glibenclamide reduces inflammation, vasogenic edema, and caspase-3 activation after subarachnoid hemorrhage. J Cereb Blood Flow Metab. 2009;29:317-330.
14. Simard JM, Tosun C, Ivanova S, Kurland DB, Hong C, Radecki L, et al. Heparin Reduces Neuroinflammation and Transsynaptic Neuronal Apoptosis in a Model of Subarachnoid Hemorrhage. Transl Stroke. Res. 2012;3(suppl 1):155-165.
15. Simard JM, Woo SK, Tsymbalyuk N, Voloshyn O, Yurovsky V, Ivanova S, et al. Glibenclamide-10-h Treatment Window in a Clinically Relevant Model of Stroke. Transl Stroke. Res. 2012;3:286-295.
16. Simard JM, Woo SK, Norenberg MD, Tosun C, Chen Z, Ivanova S, et al. Brief suppression of Abcc8 prevents autodestruction of spinal cord after trauma. Sci Transl Med. 2010;2:28ra29.
17. Mehta RI, Ivanova S, Tosun C, Castellani RJ, Gerzanich V, Simard JM. Sulfonylurea receptor 1 expression in human cerebral infarcts. J Neuropathol Exp Neurol. 2013;72:871-883.
18. Patel AD, Gerzanich V, Geng Z, Simard JM. Glibenclamide reduces hippocampal injury and preserves rapid spatial learning in a model of traumatic brain injury. J Neuropathol Exp Neurol. 2010;69:1177-1190.
19. Brody DL, Holtzman DM. Morris water maze search strategy analysis in PDAPP mice before and after experimental traumatic brain injury. Exp Neurol. 2006;197:330-340.
20. Guiot Y, Stevens M, Marhfour I, Stiernet P, Mikhailov M, Ashcroft SJ, et al. Morphological localisation of sulfonylurea receptor 1 in endocrine cells of human, mouse and rat pancreas. Diabetologia. 2007;50:1889-1899.
21. Teruyama R, Sakuraba M, Kurotaki H, Armstrong WE. Transient receptor potential channel m4 and m5 in magnocellular cells in rat supraoptic and paraventricular nuclei. J Neuroendocrinol. 2011;23:1204-1213.
22. Wagner KR, Dean C, Beiler S, Bryan DW, Packard BA, Smulian AG, et al. Plasma infusions into porcine cerebral white matter induce early edema, oxidative stress, pro-inflammatory cytokine gene expression and DNA fragmentation: implications for white matter injury with increased blood-brain-barrier permeability. Curr Neurovasc Res. 2005;2:149-155.
23. Xavier GF, Costa VC. Dentate gyrus and spatial behaviour. Prog Neuropsychopharmacol Biol Psychiatry. 2009;33:762-773.
24. Silasi G, Colbourne F. Long-term assessment of motor and cognitive behaviours in the intraluminal perforation model of subarachnoid hemorrhage in rats. Behav Brain Res. 2009;198:380-387.
25. Chen G, Li Q, Feng D, Hu T, Fang Q, Wang Z. Expression of NR2B in different brain regions and effect of NR2B antagonism on learning deficits after experimental subarachnoid hemorrhage. Neuroscience. 2013;231:136-144.
26. Jeon H, Ai J, Sabri M, Tariq A, Macdonald RL. Learning deficits after experimental subarachnoid hemorrhage in rats. Neuroscience. 2010;169:1805-1814.