Cognitive deficits in clinical and familial high risk groups for psychosis are common as in first episode schizophrenia

Schizophrenia Research

Volumn 151, Issue 1-3, 2013, Pages 265-269

  Üçok, Alp ^a   Direk, Neşe ^b   Koyuncu, Ahmet ^c   Keskin Ergen, Yasemin ^a   Yüksel, Çaǧri ^a,e   Güler, Jülide ^d   Karadayi, Gülşah ^a   Akturan, Elçin ^a   Devrim Üçok, Müge ^a  

^a ISTANBUL UNIVERSITY   (Turkey)

^b ERASMUS MEDICAL CENTER   (Netherlands)

^c Bati Bahat Hospital   (Turkey)

^d Erenkoy Menthal Hospital   (Turkey)

^e MCLEAN HOSPITAL   (United States)

Author keywords

Cognition; Familial risk; First episode schizophrenia; Ultra high risk for psychosis

Indexed keywords

ADULT; ARTICLE; ATTENTION; COGNITION; COGNITIVE DEFECT; CONTROLLED STUDY; EXECUTIVE FUNCTION; FAMILY HISTORY; FEMALE; FIRST EPISODE SCHIZOPHRENIA; GENETIC RISK; HIGH RISK POPULATION; HUMAN; LEARNING; MAJOR CLINICAL STUDY; MALE; MENTAL PERFORMANCE; NEUROPSYCHOLOGICAL TEST; PRIORITY JOURNAL; PROCESSING SPEED; PSYCHOSIS; SCHIZOPHRENIA; SCORING SYSTEM; SIBLING; WORKING MEMORY;

COGNITION; FAMILIAL RISK; FIRST EPISODE SCHIZOPHRENIA; ULTRA HIGH RISK FOR PSYCHOSIS;

ADOLESCENT; ADULT; ANALYSIS OF VARIANCE; COGNITION DISORDERS; FEMALE; HUMANS; MALE; NEUROPSYCHOLOGICAL TESTS; PSYCHIATRIC STATUS RATING SCALES; PSYCHOTIC DISORDERS; RISK; RISK FACTORS; SCHIZOPHRENIA; SCHIZOPHRENIC PSYCHOLOGY; YOUNG ADULT;

EID: 84889098139     PISSN: 09209964     EISSN: 15732509     Source Type: Journal    
DOI: 10.1016/j.schres.2013.10.030     Document Type: Article

References (35)

1. Agnew-Blais J., Seidman L.J. Neurocognition in youth and young adults under age 30 at familial risk for schizophrenia: a quantitative and qualitative review. Cogn. Neuropsychiatry 2013, 18:44-82.
2. Andreasen N.C. The Scale for the Assessment of Negative Symptoms (SANS) 1983, University of Iowa, Iowa City.
3. Andreasen N.C. The Scale for the Assessment of Positive Symptoms (SAPS) 1984, University of Iowa, Iowa City.
4. Becker H.E., Nieman D.H., Wiltink S., Dingemans P.M., van de Fliert J.R., Velthorst E., de Haan L., van Amelsvoort T.A., Linszen D.H. Neurocognitive functioning before and after the first psychotic episode: does psychosis result in cognitive deterioration?. Psychol. Med. 2010, 40:1599-1606.
5. Bertisch H.C., Fava J., Kattan A., DeLisi L.E. Preliminary neuropsychological findings in individuals at high genetic risk for schizophrenia. Early Interv. Psychiatry 2008, 2:45-49.
6. Besnier N., Richard F., Zendjidjian X., Kaladjian A., Mazzola-Pomietto P., Adida M., Azorin J.M. Stroop and emotional Stroop interference in unaffected relatives of patients with schizophrenic and bipolar disorders: distinct markers of vulnerability?. World J. Biol. Psychiatry 2009, 1:809-818.
7. Bora E., Murray R.M. Meta-analysis of cognitive deficits in ultra-high risk to psychosis and first-episode psychosis: do the cognitive deficits progress over, or after, the onset of psychosis? 2013, Schizophr Bull, (Epub ahead of print, Jun 14, in press).
8. Breton F., Plante A., Legauffre C., Morel N., Ades J., Gorwood P., Ramoz N., Dubertret C. The executive control of attention differentiates patients with schizophrenia, their first-degree relatives and healthy controls. Neuropsychologia 2011, 49:203-208.
9. de la Serna E., Baeza I., Andres S., Puig O., Sanchez-Guistau V., Romero S., Bernardo M., Moreno D., Noguera A., Castro-Fornieles J. Comparison between young siblings and offspring of subjects with schizophrenia: clinical and neuropsychological characteristics. Schizophr. Res. 2011, 131:35-42.
10. First M.B., Spitzer R.L., Goibbon M., Williams J.B.W. Structured Clinical Interview for DSM-IV Axis I disorders (SCID-I), clinical version, Washington, DC 1997.
11. Galderisi S., Davidson M., Kahn R.S., Mucci A., Boter H., Gheorghe M.D., Rybakowski J.K., Libiger J., Dollfus S., Lopez-Ibor J.J., Peuskens J., Hranov L.G., Fleischhacker W.W., group, E. Correlates of cognitive impairment in first episode schizophrenia: the EUFEST study. Schizophr. Res. 2009, 115:104-114.
12. Golden C. The Stroop Color and Word Test: A Manual for Clinical and Experimental Uses 1978, Stoelting Co., Chicago.
13. Giuliano A.J., Li H., Mesholam-Gately R.I., Sorenson S.M., Woodberry K.A., Seidman L.J. Neurocognition in the psychosis risk syndrome: a quantitative and qualitative review. Curr. Pharm. Des. 2012, 18:399-415.
14. Hawkins K.A., Keefe R.S., Christensen B.K., Addington J., Woods S.W., Callahan J., Zipursky R.B., Perkins D.O., Tohen M., Breier A., McGlashan T.H. Neuropsychological course in the prodrome and first episode of psychosis: findings from the PRIME North America Double Blind Treatment Study. Schizophr. Res. 2008, 105:1-9.
15. Heaton R.K., Chelune G.J., Talley J.L., Kay G.G., Curtiss G. Wisconsin Card Sorting Test manual: revised and expanded 1993, Psychological Assessment Resources, Odessa, FL.
16. Heydebrand G., Weiser M., Rabinowitz J., Hoff A.L., DeLisi L.E., Csernansky J.G. Correlates of cognitive deficits in first episode schizophrenia. Schizophr. Res. 2004, 68(1):1-9.
17. Kelleher I., Clarke M.C., Rawdon C., Murphy J., Cannon M. Neurocognition in the extended psychosis phenotype: performance of a community sample of adolescents with psychotic symptoms on the MATRICS Neurocognitive Battery. Schizophr. Bull. 2012, 39:1018-1026.
18. Kelleher I., Murtagh A., Clarke M.C., Murphy J., Rawdon C., Cannon M. Neurocognitive performance of a community-based sample of young people at putative ultra high risk for psychosis: support for the processing speed hypothesis. Cogn. Neuropsychiatry 2013, 18:9-25.
19. Kim H.S., Shin N.Y., Jang J.H., Kim E., Shim G., Park H.Y., Hong K.S., Kwon J.S. Social cognition and neurocognition as predictors of conversion to psychosis in individuals at ultra-high risk. Schizophr. Res. 2011, 130:170-175.
20. Lencz T., Smith C.W., McLaughlin D., Auther A., Nakayama E., Hovey L., Cornblatt B.A. Generalized and specific neurocognitive deficits in prodromal schizophrenia. Biol. Psychiatry 2006, 59:863-871.
21. Maziade M., Rouleau N., Merette C., Cellard C., Battaglia M., Marino C., Jomphe V., Gilbert E., Achim A., Bouchard R.H., Paccalet T., Paradis M.E., Roy M.A. Verbal and visual memory impairments among young offspring and healthy adult relatives of patients with schizophrenia and bipolar disorder: selective generational patterns indicate different developmental trajectories. Schizophr. Bull. 2011, 37:1218-1228.
22. McGorry P.D., Allott K., Jackson H.J. Diagnosis and the staging model of psychosis. The recognition and management of early psychosis 2009, 17-27. Cambridge University Press, Cambridge. H.J. Jackson, P.D. McGorry (Eds.).
23. Mukkala S., Ilonen T., Nordström T., Miettunen J., Loukkola J., Barnett J.H., Murray G.K., Jääskeläinen E., Mäki P., Taanila A., Moilanen I., Jones P.B., Heinimaa M., Veijola J. Different vulnerability indicators for psychosis and their neuropsychological characteristics in the Northern Finland 1986 Birth Cohort. J. Clin. Exp. Neuropsychol. 2011, 33:385-394.
24. Pukrop R., Schultze-Lutter F., Ruhrmann S., Brockhaus-Dumke A., Tendolkar I., Bechdolf A., Matuschek E., Klosterkotter J. Neurocognitive functioning in subjects at risk for a first episode of psychosis compared with first- and multiple-episode schizophrenia. J. Clin. Exp. Neuropsychol. 2006, 28:1388-1407.
25. Reitan R.M. The relation of the trail making test to organic brain damage. J. Consult. Psychol. 1955, 19:393-394.
26. Rey A. L'examen clinique en psychologie 1964, Presses Universitaires de France, Paris.
27. Seidman L.J., Giuliano A.J., Smith C.W., Stone W.S., Glatt S.J., Meyer E., Faraone S.V., Tsuang M.T., Cornblatt B. Neuropsychological functioning in adolescents and young adults at genetic risk for schizophrenia and affective psychoses: results from the Harvard and Hillside Adolescent High Risk Studies. Schizophr. Bull. 2006, 32:507-524.
28. Seidman L.J., Giuliano A.J., Meyer E.C., Addington J., Cadenhead K.S., Cannon T.D., McGlashan T.H., Perkins D.O., Tsuang M.T., Walker E.F., Woods S.W., Bearden C.E., Christensen B.K., Hawkins K., Heaton R., Keefe R.S., Heinssen R., Cornblatt B.A., North American Prodrome Longitudinal Study, G. Neuropsychology of the prodrome to psychosis in the NAPLS consortium: relationship to family history and conversion to psychosis. Arch. Gen. Psychiatry 2010, 67:578-588.
29. Torniainen M., Suvisaari J., Partonen T., Castaneda A.E., Kuha A., Perala J., Saarni S., Lonnqvist J., Tuulio-Henriksson A. Sex differences in cognition among persons with schizophrenia and healthy first-degree relatives. Psychiatry Res. 2011, 188:7-12.
30. Ucok A., Polat A., Genc A., Cakir S., Turan N. Duration of untreated psychosis may predict acute treatment response in first-episode schizophrenia. J. Psychiatr. Res. 2004, 38:163-168.
31. Ucok A., Polat A., Cakir S., Genc A. One year outcome in first episode schizophrenia. Predictors of relapse. Eur. Arch. Psychiatry Clin. Neurosci. 2006, 256:37-43.
32. Ventura J., Green M.F., Shaner A., Liberman R. Training and quality assurance with the Brief Psychiatric Rating Scale: "the drift busters". Int. J. Methods Psychiatr. Res. 1993, 3:221-244.
33. Wechler D. WMS-R:Weschler Memory Scale-Revised (The Psychological Corporation) 1987, Harcourt, Brace, Jovanovich, New York.
34. Woodberry K.A., Seidman L.J., Giuliano A.J., Verdi M.B., Cook W.L., McFarlane W.R. Neuropsychological profiles in individuals at clinical high risk for psychosis: relationship to psychosis and intelligence. Schizophr. Res. 2010, 123:188-198.
35. Yung A.R., Phillips L.J., McGorry P.D., McFarlane C.A., Francey S., Harrigan S., Patton G.C., Jackson H.J. Prediction of psychosis. A step towards indicated prevention of schizophrenia. Br. J. Psychiatry Suppl. 1998, 172:14-20.