Targeting the autonomic nervous system: Measuring autonomic function and novel devices for heart failure management

International Journal of Cardiology

Volumn 170, Issue 2, 2013, Pages 107-117

  Patel, Hitesh C ^a,b   Rosen, Stuart D ^b   Lindsay, Alistair ^a   Hayward, Carl ^a,b   Lyon, Alexander R ^a,b   Di Mario, Carlo ^a  

^a ROYAL BROMPTON HOSPITAL   (United Kingdom)

^b NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

Author keywords

Autonomic nervous system; Devices; Heart failure; Renal denervation; Sympathetic nervous system

Indexed keywords

ENALAPRIL; HYDRALAZINE PLUS ISOSORBIDE DINITRATE; MOXONIDINE; NORADRENALIN; PLACEBO; PYRIDOSTIGMINE; SCOPOLAMINE;

AUTONOMIC NERVOUS SYSTEM; BLOOD PRESSURE; CARDIOVASCULAR THERAPEUTIC DEVICE; CHOLINERGIC SYSTEM; DEVICE THERAPY; HEART FAILURE; HEART RATE VARIABILITY; HUMAN; KIDNEY DENERVATION; MICRONEUROGRAPHY; NEUROGRAPHY; NONHUMAN; PARASYMPATHETIC TONE; PERIPHERAL NERVE STIMULATOR; PRESSORECEPTOR REFLEX; PRIORITY JOURNAL; REVIEW; SPINAL CORD STIMULATION; SYMPATHETIC INNERVATION; SYMPATHETIC TONE; VAGUS NERVE STIMULATION;

AUTONOMIC NERVOUS SYSTEM; DEVICES; HEART FAILURE; RENAL DENERVATION; SYMPATHETIC NERVOUS SYSTEM;

ANIMALS; AUTONOMIC NERVOUS SYSTEM DISEASES; ELECTRIC STIMULATION THERAPY; HEART; HEART FAILURE; HUMANS; SYMPATHECTOMY; SYMPATHETIC NERVOUS SYSTEM;

EID: 84889097953     PISSN: 01675273     EISSN: 18741754     Source Type: Journal    
DOI: 10.1016/j.ijcard.2013.10.058     Document Type: Review

References (84)

1. A. Katz The 'modern' view of heart failure. How did we get here? Circ Heart Fail 1 2008 63 71
2. S. Laribi, A. Aourba, and M. Nikolaou Trends in death attributed to heart failure over the past two decades in Europe Eur J Heart Fail 14 2012 234 239
3. Meta-analysis Global Group in Chronic Heart Failure (MAGGIC) The survival of patients with heart failure with preserved or reduced left ventricular ejection fraction: an individual patient data meta-analysis Eur Heart J 33 2012 1750 1757
4. G.S. Francis, C. Benedict, and D.E. Johnstone Comparison of neuroendocrine activation in patients with left ventricular dysfunction with and without congestive heart failure. A substudy of the Studies of Left Ventricular Dysfunction (SOLVD) Circulation 82 1990 1724 1729
5. J. Floras Sympathetic nervous system activation in human heart failure: clinical implications of an updated model J Am Coll Cardiol 54 2009 375 385
6. S. Lamba, and W. Abraham Alterations in adrenergic receptor signalling in heart failure Heart Fail Rev 5 2000 7 16
7. P. Sobotka, H. Krum, M. Bohm, D. Francis, and M. Schlaich The role of renal denervation in the treatment of heart failure Curr Cardiol Rep 14 2012 285 292
8. C. Chidsey, E. Braunwald, A. Morrow, and D. Mason Myocardial norepinephrine concentration in man: effects of reserpine and of congestive heart failure N Engl J Med 269 1963 653 658
9. C. Chidsey, G. Kaiser, E. Sonnenblick, J. Spann, and E. Braunwald Cardiac norepinephrine stores in experimental heart failure in the dog J Clin Investig 43 1964 2386 2393
10. J. Thomas, and B. Marks Plasma norepinephrine in congestive heart failure Am J Cardiol 41 1978 233 243
11. J. Cohn, B. Levine, and M. Olivari Plasma norepinephrine as a guide to prognosis in patients with chronic congestive heart failure N Engl J Med 311 1984 819 823
12. G. Grassi, G. Bolla, F. Quarti-Trevano, F. Arenare, G. Brambilla, and G. Mancia Sympathetic activation in congestive heart failure: reproducibility of neuroadrenergic markers Eur J Heart Fail 10 2008 1186 1191
13. F. Triposkiades, G. Karayannis, G. Giamouzis, J. Skoularigis, G. Louridas, and J. Butler The sympathetic nervous system in heart failure. Physiology, pathophysiology, and clinical implications J Am Coll Cardiol 54 2009 1747 1762
14. M. Esler, G. Jennings, and P. Korner Assessment of human sympathetic nervous system activity from measurements of norepinephrine turnover Hypertension 11 1988 3 20
15. I.T. Meredith, G. Eisenhofer, G.W. Lambert, E.M. Dewar, G.L. Jennings, and M.D. Esler Cardiac sympathetic activity in congestive heart failure: evidence for increased neuronal norepinephrine release and preserved neuronal uptake Circulation 88 1993 136 145
16. T. Mano, S. Iwase, and S. Toma Microneurography as a tool in clinical neurophysiology to investigate peripheral neural traffic in humans Clin Neurophysiol 117 2006 2357 2384
17. W. Leimbach, B. Wallin, R. Victor, P. Aylward, G. Sundlof, and A. Mark Direct evidence from intraneural recordings for increased central sympathetic outflow in patients with heart failure Circulation 73 1986 913 919
18. A. Barretto, A. Santos, and R. Munhoz Increased muscle sympathetic nerve activity predicts mortality in heart failure patients Int J Cardiol 135 2009 302 307
19. L. De Matos, G. Gardenghi, and M. Urbana Impact of 6 months of therapy with carvedilol on muscle sympathetic nerve activity in heart failure patients J Card Fail 10 2004 496 502
20. B. Najem, P. Unger, and N. Preumont Sympathetic control after cardiac resynchronization therapy: responders versus nonresponders Am J Physiol Heart Circ Physiol 291 2006 H2647 H2652
21. M. Schlaich, P. Sobotka, H. Krum, E. Lambert, and M. Elser Renal sympathetic-nerve ablation for uncontrolled hypertension N Engl J Med 361 2009 932 933
22. B. Rundquist, M. Elam, Y. Bergmann-Sverrisdottir, G. Eisenhofer, and P. Friberg Increased cardiac adrenergic drive precedes generalized sympathetic activation in human heart failure Circulation 95 1997 169 175
23. P.G. Katona, M. McLean, D.H. Dighton, and A. Guz Sympathetic and parasympathetic cardiac control in athletes and nonathletes at rest J Appl Physiol 52 1982 1652 1657
24. M. Lahiri, P. Kannankeril, and J. Goldberger Assessment of autonomic function in cardiovascular disease: physiological basis and prognostic information J Am Coll Cardiol 51 2008 1725 1733
25. D. Nanchen, M. Leening, and I. Locatelli Resting heart rate and the risk of heart failure in healthy adults. The Rotterdam Study Circ Heart Fail 6 2013 403 410
26. M. Bohm, K. Swedberg, and M. Komajda Heart rate as a risk factor in chronic heart failure (SHIFT): the association between heart rate and outcomes in a randomised placebo-controlled trial Lancet 376 2010 886 894
27. D.J. Ewing, C.N. Martyn, R.J. Young, and B.F. Clarke The value of cardiovascular autonomic function tests: 10 years experience in diabetes Diabetes Care 8 1985 491 498
28. H. Patel, B. Ozdemir, M. Patel, H. Xiao, P. Poole-Wilson, and S. Rosen Impairment of autonomic reactivity is a feature of heart failure whether or not the left ventricular ejection fraction in normal Int J Cardiol 151 2011 34 39
29. Task Force of the European Society of Cardiology, and The North American Society of Pacing and Electrophysiology Heart rate variability. Standards of measurement, physiological interpretation, and clinical use Eur Heart J 17 1996 354 381
30. M. La Rovere, G. Pinna, and R. Maestri Short-term heart rate variability strongly predicts sudden cardiac death in chronic heart failure patients Circulation 107 2003 565 570
31. J. Nolan, P. Batin, and R. Andrews Prospective study of heart rate variability and mortality in chronic heart failure: results of the United Kingdom heart failure evaluation and assessment of risk trial (UK-Heart) Circulation 98 1998 1510 1516
32. F. Pousset, X. Copie, and P. Lechat Effects of bisoprolol on heart rate variability in heart failure Am J Cardiol 77 1996 612 617
33. M. La Rovere, G. Pinna, and G. Raczak Baroreflex sensitivity: measurement and clinical implications Ann Noninvasive Electrocardiol 13 2008 191 207
34. M. La Rovere, G. Pinna, and R. Maestri Prognostic implication of baroreflex sensitivity in heart failure patients in the beta-blocking era J Am Coll Cardiol 53 2009 193 199
35. A. Bauer, M. Malik, and G. Schmidt Heart rate turbulence: standards of measurement, physiological interpretation, and clinical use J Am Coll Cardiol 17 2008 1353 1365
36. I. Cygankiewicz, W. Zareba, and R. Vazquez Heart rate turbulence predicts all-cause mortality and sudden death in congestive heart failure patients Heart Rhythm 5 2008 1095 1102
37. F. Bengel Imaging targets of the sympathetic nervous system of the heart: translational considerations J Nucl Med 52 2011 1167 1170
38. I. Carrio, M. Cowie, J. Yamazaki, J. Udelson, and P. Camici Cardiac sympathetic imaging with mIBG in heart failure J Am Coll Cardiol Cardiovasc Imaging 3 2010 92 100
39. 123I-metaiodobenzylguanidine (MIBG) parameters in patients with heart failure: a systematic review Eur Heart J 29 2008 1147 1159
40. A. Jacobsen, R. Senior, and M. Cerqueira Myocardial iodine-123 meta-iodobenzylguanidine imaging and cardiac events in heart failure J Am Coll Cardiol 55 2010 2212 2221
41. P. Lechat, M. Packer, S. Chalon, M. Cucherat, T. Arab, and J.P. Boiseel Clinical effects of beta-adrenergic blockade in chronic heart failure: a meta-analysis of double-blind, placebo-controlled, randomized trials Circulation 98 1998 1184 1191
42. G. Grassi, B. Cattaneo, and G. Seravelle Effects of chronic ACE inhibition on sympathetic nerve traffic and baroreflex control of circulation in heart failure Circulation 96 1997 1173 1179
43. J. Cohn, G. Johnson, and S. Ziesche A comparison of enalapril with hydralazine-isosorbide dinitrate in the treatment of chronic congestive heart failure N Engl J Med 325 1991 303 310
44. A. Allen, I. Moeller, and T. Jenkins Angiotensin receptors in the nervous system Brain Res Bull 47 1998 17 28
45. M. Samuels The brain-heart connection Circulation 116 2007 77 84
46. K.I. Melville, B. Blum, H.E. Shister, and M.D. Silver Cardiac ischemic changes and arrhythmias induced by hypothalamic stimulation Am J Cardiol 12 1963 781 791
47. J.H. Greenhoot, and D.D. Reichenbach Cardiac injury and subarachnoid hemorrhage. A clinical, pathological, and physiological correlation J Neurosurg 30 1969 521 531
48. A. Aggarwal, M.D. Esler, M.J. Morris, G. Lambert, and D.M. Kaye Regional sympathetic effects of low-dose clonidine in heart failure Hypertension 41 3 2003 Mar 553 557
49. A.J. Moorman, J.R. Stratton, and W.C. Levy Clonidine therapy in patients with heart failure improves exercise efficiency, functional class and symptoms Int J Cardiol 150 3 2011 Aug 4 372 373
50. C. Lang, G. Rayos, D. Chomsky, A. Wood, and J. Wilson Effect of sympathoinhibition on exercise performance in patients with heart failure Circulation 96 1997 238 245
51. J. Cohn, M. Pfeffer, and J. Rouleau Adverse mortality effect of central sympathetic inhibition with sustained-release moxonidine in patients with heart failure (MOXCON) Eur J Heart Fail 5 2003 659 667
52. B. Olshansky, H. Sabbah, P. Hauptman, and W. Colucci Parasympathetic nervous system and heart failure. Pathophysiology and potential implications for therapy Circulation 118 2008 863 871
53. A. Behling, R. Moraes, and L. Rohde Cholinergic stimulation with pyridostigmine reduces ventricular arrhythmia and enhances heart rate variability in heart failure Am Heart J 146 2003 494 500
54. S. Serra, R. Costa, R. Castro, S. Xavier, and A. Da Nobrega Cholinergic stimulation improves autonomic and hemodynamic profile during dynamic exercise in patients with heart failure J Card Fail 15 2009 124 129
55. B. Casadei, J. Conway, C. Forfar, and P. Sleight Effect of low doses of scopolamine on RR interval variability, baroreflex sensitivity, and exercise performance in patients with chronic heart failure Heart 75 1996 274 280
56. A. Coats, S. Adamopoulos, and A. Radaelli Controlled trial of physical training in chronic heart failure. Exercise performance, hemodynamics, ventilation, and autonomic function Circulation 85 1992 2119 2131
57. M. Kivimaki, M. Virtanen, M. Elovainio, A. Kouvonen, A. Vaananen, and J. Vahtera Work stress in the etiology of coronary heart disease - a meta-analysis Scand J Work Environ Health 32 2006 431 442
58. J. Curiati, E. Bocchi, and J. Freire Meditation reduces sympathetic activation and improves the quality of life in elderly patients with optimally treated heart failure: a prospectively randomised study J Altern Complement Med 11 2005 465 472
59. M. Petersson, P. Friberg, G. Eisenhofer, G. Lambert, and B. Rundqvist Long-term outcome in relation to renal sympathetic activity in patients with chronic heart failure Eur Heart J 26 2005 906 913
60. T. Nozawa, A. Igawa, and N. Fuji Effects of long-term renal sympathetic denervation on heart failure after myocardial infarction in rats Heart Vessels 16 2002 51 56
61. Symplicity HTN-2 Investigators Renal sympathetic denervation in patients with treatment-resistant hypertension (The Symplicity HTN-2 Trial): a randomised controlled trial Lancet 376 2010 1903 1909
62. J. Davies, C. Manistry, and R. Petraco First-in-man safety evaluation of renal denervation for chronic systolic heart failure: primary outcome from REACH-Pilot study Int J Cardiol 162 2013 189 192
63. M. Taborsky, M.L. Lazarova, and J. Vaclavik The effect of renal denervation in patients with advanced heart failure Eur Heart J 33 2012 517 [Abstract Supplement]
64. H. Sabbah Baroreflex activation for the treatment of heart failure Curr Cardiol Rep 14 2012 326 333
65. D. Georgakopoulos, W. Little, W. Abraham, F. Weaver, and M. Zile Chronic baroreflex activation: a potential therapeutic approach to heart failure with preserved ejection fraction J Card Fail 17 2011 167 178
66. S. Malpas Sympathetic nervous system overactivity and its role in the development of cardiovascular disease Physiol Rev 90 2010 513 557
67. M. La Rovere, J. Bigger, F. Marcus, and P. Schwartz Baroreflex sensitivity and heart-rate variability in prediction of total cardiac mortality after myocardial infarction. ATRAMI (Autonomic Tone and Reflexes After Myocardial Infarction) investigators Lancet 351 1998 478 484
68. M. Gademan, R. van Bommel, and C. Ypenburg Biventricular pacing in chronic heart failure acutely facilitates the arterial baroreflex Am J Physiol Heart 295 2008 H755 H760
69. I. Zucker, J. Hackley, and K. Cornish Chronic baroreceptor activation enhances survival in dogs with pacing induced heart failure Hypertension 50 2007 904 910
70. I. Scheffers, A. Kroon, and J. Schmidli Novel baroreflex activation therapy in resistant hypertension: results of a European multicenter feasibility study J Am Coll Cardiol 56 2010 1254 1258
71. J. Bisognano, G. Bakris, and M. Nadim Baroreflex activation therapy lowers blood pressure in patients with resistant hypertension J Am Coll Cardiol 58 2011 765 773
72. E. Gronda, G. Grassi, and G. Costantino Acute baroreflex activation therapy improved hemodynamics in heart failure with reduced ejection fraction: early results from a chronic pilot investigation Circulation 126 2012 A15570
73. M. Halbach, N. Madershahian, and M. Brandt Baroreflex activation therapy significantly lowers NTproBNP in patients with symptomatic heart failure Circulation 126 2012 A15273
74. J. Bisognano, P. de Leeuw, D. Bach, and E. Lovett Improved cardiac structure and function in early-stage heart failure with chronic treatment with an implantable device: results from European and United States trials of the Rheos System J Card Fail 14 6 2008 S48
75. B. Olshansky, H. Sabbah, P. Hauptman, and W. Colucci Parasympathetic nervous system and heart failure: pathophysiology and potential implications for therapy Circulation 118 2008 863 871
76. P.J. Schwartz, M. Pagani, and F. Lombardi A cardiocardiac sympathovagal reflex in the cat Circ Res 32 1973 215 220
77. P. Schwartz Vagal stimulation for the treatment of heart failure: a translational success story Heart 98 2012 1687 1689
78. P. Schwartz, G. De Ferrari, and A. Sanzo Long-term vagal stimulation in patients with advanced heart failure: first experience in man Eur J Heart Fail 10 2008 884 891
79. Z. Issa, X. Zhou, and M. Ujhelyi Thoracic spinal cord stimulation reduces the risk of ischemic ventricular arrhythmias in a post infarction heart failure canine model Circulation 111 2005 3217 3220
80. J. Olgin, T. Takahashi, and E. Wilson Effects of thoracic spinal cord stimulation on cardiac autonomic regulation of the sinus and atrioventricular nodes J Cardiovasc Electrophysiol 13 2002 475 481
81. D. Schultz, Z. Xiaohong, A. Singal, and S. Musley Cardiovascular effects of spinal cord stimulation in hypertensive patients Pain Physician 14 2011 1 14
82. J. Lopshire, X. Zhou, and C. Dusa Spinal cord stimulation improves ventricular function and reduces ventricular arrhythmias in a canine postinfarction heart failure model Circulation 120 2009 286 294
83. H. Tse, Y. Liu, and M. Zuo Intermittent versus continuous thoracic spinal cord stimulation for treatment of ischemic heart failure Eur Heart J 33 2012 963 964 [Abstract supplement]
84. M. Mehra, P. Uber, and G. Francis Heart failure therapy at a crossroad: are there limits to the neurohormonal model? J Am Coll Cardiol 41 2003 1606 1610