메뉴 건너뛰기




Volumn 288, Issue 48, 2013, Pages 34757-34766

Oral administration of transforming growth Factor-β1 (TGF-β1) protects the immature gut from injury via smad proteindependent suppression of epithelial nuclear factor κb (NF-κB) signaling and proinflammatory cytokine production

Author keywords

[No Author keywords available]

Indexed keywords

ANTI-INFLAMMATORY EFFECTS; CHROMATIN IMMUNOPRECIPITATION ASSAY; GASTROINTESTINAL DISEASE; INFLAMMATORY IMMUNE RESPONSE; INTESTINAL EPITHELIAL CELLS; INTESTINAL EPITHELIUM; PROINFLAMMATORY CYTOKINES; TRANSFORMING GROWTH FACTORS;

EID: 84889009371     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.503946     Document Type: Article
Times cited : (40)

References (36)
  • 2
    • 0035007355 scopus 로고    scopus 로고
    • Hypothesis: Inappropriate colonization of the premature intestine can cause neonatal necrotizing enterocolitis
    • Claud, E. C., and Walker, W. A. (2001) Hypothesis: inappropriate colonization of the premature intestine can cause neonatal necrotizing enterocolitis. FASEB J. 15, 1398-1403
    • (2001) FASEB J. , vol.15 , pp. 1398-1403
    • Claud, E.C.1    Walker, W.A.2
  • 3
    • 2442616098 scopus 로고    scopus 로고
    • Developmentally regulated IκB expression in intestinal epithelium and susceptibility to flagellin-induced inflammation
    • Claud, E. C., Lu, L., Anton, P. M., Savidge, T., Walker, W. A., and Cherayil, B. J. (2004) Developmentally regulated IκB expression in intestinal epithelium and susceptibility to flagellin-induced inflammation. Proc. Natl. Acad. Sci. U.S.A. 101, 7404-7408
    • (2004) Proc. Natl. Acad. Sci. U.S.A. , vol.101 , pp. 7404-7408
    • Claud, E.C.1    Lu, L.2    Anton, P.M.3    Savidge, T.4    Walker, W.A.5    Cherayil, B.J.6
  • 4
    • 40749097167 scopus 로고    scopus 로고
    • The importance of proinflammatory signaling in neonatal necrotizing enterocolitis
    • Frost, B. L., Jilling, T., and Caplan, M. S. (2008) The importance of proinflammatory signaling in neonatal necrotizing enterocolitis. Semin. Perinatol. 32, 100-106
    • (2008) Semin. Perinatol , vol.32 , pp. 100-106
    • Frost, B.L.1    Jilling, T.2    Caplan, M.S.3
  • 5
    • 61849127839 scopus 로고    scopus 로고
    • The IκB kinase complex: Master regulator of NF-κB signaling
    • Solt, L. A., and May, M. J. (2008) The IκB kinase complex: master regulator of NF-κB signaling. Immunol. Res. 42, 3-18
    • (2008) Immunol. Res , vol.42 , pp. 3-18
    • Solt, L.A.1    May, M.J.2
  • 6
    • 47549090432 scopus 로고    scopus 로고
    • TGFβ in cancer
    • Massagué, J. (2008) TGFβ in cancer. Cell 134, 215-230
    • (2008) Cell , vol.134 , pp. 215-230
    • Massagué, J.1
  • 9
    • 84859979309 scopus 로고    scopus 로고
    • TGF-β2 induces maturation of immature human intestinal epithelial cells and inhibits inflammatory cytokine responses induced via the NF-κB pathway
    • Rautava, S., Lu, L., Nanthakumar, N. N., Dubert-Ferrandon, A., and Walker, W. A. (2012) TGF-β2 induces maturation of immature human intestinal epithelial cells and inhibits inflammatory cytokine responses induced via the NF-κB pathway. J. Pediatr. Gastroenterol. Nutr. 54, 630-638
    • (2012) J. Pediatr. Gastroenterol. Nutr , vol.54 , pp. 630-638
    • Rautava, S.1    Lu, L.2    Nanthakumar, N.N.3    Dubert-Ferrandon, A.4    Walker, W.A.5
  • 10
    • 0344586810 scopus 로고    scopus 로고
    • Inhibition of CK2 activity by TGF-β1 promotes IκB-α protein stabilization and apoptosis of immortalized hepatocytes
    • Cavin, L. G., Romieu-Mourez, R., Panta, G. R., Sun, J., Factor, V. M., Thorgeirsson, S. S., Sonenshein, G. E., and Arsura, M. (2003) Inhibition of CK2 activity by TGF-β1 promotes IκB-α protein stabilization and apoptosis of immortalized hepatocytes. Hepatology 38, 1540-1551
    • (2003) Hepatology , vol.38 , pp. 1540-1551
    • Cavin, L.G.1    Romieu-Mourez, R.2    Panta, G.R.3    Sun, J.4    Factor, V.M.5    Thorgeirsson, S.S.6    Sonenshein, G.E.7    Arsura, M.8
  • 11
    • 0033542506 scopus 로고    scopus 로고
    • TGF-β1 inhibits NF-κB activity through induction of IκB-α expression in human salivary gland cells: A possible mechanism of growth suppression by TGF-β1
    • Azuma, M., Motegi, K., Aota, K., Yamashita, T., Yoshida, H., and Sato, M. (1999) TGF-β1 inhibits NF-κB activity through induction of IκB-α expression in human salivary gland cells: a possible mechanism of growth suppression by TGF-β1. Exp. Cell Res. 250, 213-222
    • (1999) Exp. Cell Res , vol.250 , pp. 213-222
    • Azuma, M.1    Motegi, K.2    Aota, K.3    Yamashita, T.4    Yoshida, H.5    Sato, M.6
  • 12
    • 0029020511 scopus 로고
    • Establishment of a human fetal small intestinal epithelial cell line
    • Sanderson, I. R., and Walker, W. A. (1995) Establishment of a human fetal small intestinal epithelial cell line. Int. Arch. Allergy Immunol. 107, 396-397
    • (1995) Int. Arch. Allergy Immunol , vol.107 , pp. 396-397
    • Sanderson, I.R.1    Walker, W.A.2
  • 13
    • 0028020174 scopus 로고
    • Role of asphyxia and feeding in a neonatal rat model of necrotizing enterocolitis
    • Caplan, M. S., Hedlund, E., Adler, L., and Hsueh, W. (1994) Role of asphyxia and feeding in a neonatal rat model of necrotizing enterocolitis. Pediatr. Pathol. 14, 1017-1028
    • (1994) Pediatr. Pathol , vol.14 , pp. 1017-1028
    • Caplan, M.S.1    Hedlund, E.2    Adler, L.3    Hsueh, W.4
  • 15
    • 33845931845 scopus 로고    scopus 로고
    • Smad4-dependent regulation of urokinase plasminogen activator secretion and RNA stability associated with invasiveness by autocrine and paracrine Transforming growth factor-β
    • Shiou, S. R., Datta, P. K., Dhawan, P., Law, B. K., Yingling, J. M., Dixon, D. A., and Beauchamp, R. D. (2006) Smad4-dependent regulation of urokinase plasminogen activator secretion and RNA stability associated with invasiveness by autocrine and paracrine Transforming growth factor-β. J. Biol. Chem. 281, 33971-33981
    • (2006) J. Biol. Chem , vol.281 , pp. 33971-33981
    • Shiou, S.R.1    Datta, P.K.2    Dhawan, P.3    Law, B.K.4    Yingling, J.M.5    Dixon, D.A.6    Beauchamp, R.D.7
  • 16
    • 0034062353 scopus 로고    scopus 로고
    • The luminal short-chain fatty acid butyrate modulates NF-κB activity in a human colonic epithelial cell line
    • Inan, M. S., Rasoulpour, R. J., Yin, L., Hubbard, A. K., Rosenberg, D. W., and Giardina, C. (2000) The luminal short-chain fatty acid butyrate modulates NF-κB activity in a human colonic epithelial cell line. Gastroenterology 118, 724-734
    • (2000) Gastroenterology , vol.118 , pp. 724-734
    • Inan, M.S.1    Rasoulpour, R.J.2    Yin, L.3    Hubbard, A.K.4    Rosenberg, D.W.5    Giardina, C.6
  • 17
    • 33644873467 scopus 로고    scopus 로고
    • Two-step cross-linking method for identification of NF-κB gene network by chromatin immunoprecipitation
    • Nowak, D. E., Tian, B., and Brasier, A. R. (2005) Two-step cross-linking method for identification of NF-κB gene network by chromatin immunoprecipitation. BioTechniques 39, 715-725
    • (2005) BioTechniques , vol.39 , pp. 715-725
    • Nowak, D.E.1    Tian, B.2    Brasier, A.R.3
  • 18
    • 7644225521 scopus 로고    scopus 로고
    • Woodchuck interleukin-6 gene: Structure, characterization, and biologic activity
    • Li, D. H., Kumanogoh, A., Cao, T. M., Parnes, J. R., and Cullen, J. M. (2004) Woodchuck interleukin-6 gene: structure, characterization, and biologic activity. Gene 342, 157-164
    • (2004) Gene , vol.342 , pp. 157-164
    • Li, D.H.1    Kumanogoh, A.2    Cao, T.M.3    Parnes, J.R.4    Cullen, J.M.5
  • 19
    • 33750802140 scopus 로고    scopus 로고
    • A novel role of hypoxia-inducible factor in cobalt chloride- and hypoxia-mediated expression of IL-8 chemokine in human endothelial cells
    • Kim, K. S., Rajagopal, V., Gonsalves, C., Johnson, C., and Kalra, V. K. (2006) A novel role of hypoxia-inducible factor in cobalt chloride- and hypoxia-mediated expression of IL-8 chemokine in human endothelial cells. J. Immunol. 177, 7211-7224
    • (2006) J. Immunol , vol.177 , pp. 7211-7224
    • Kim, K.S.1    Rajagopal, V.2    Gonsalves, C.3    Johnson, C.4    Kalra, V.K.5
  • 22
    • 0037370827 scopus 로고    scopus 로고
    • Modulation of human intestinal epithelial cell IL-8 secretion by human milk factors
    • Claud, E. C., Savidge, T., and Walker, W. A. (2003) Modulation of human intestinal epithelial cell IL-8 secretion by human milk factors. Pediatr. Res. 53, 419-425
    • (2003) Pediatr. Res , vol.53 , pp. 419-425
    • Claud, E.C.1    Savidge, T.2    Walker, W.A.3
  • 23
    • 0027168447 scopus 로고
    • NF-κB controls expression of inhibitor IκBα: Evidence for an inducible autoregulatory pathway
    • Sun, S. C., Ganchi, P. A., Ballard, D. W., and Greene, W. C. (1993) NF-κB controls expression of inhibitor IκBα: evidence for an inducible autoregulatory pathway. Science 259, 1912-1915
    • (1993) Science , vol.259 , pp. 1912-1915
    • Sun, S.C.1    Ganchi, P.A.2    Ballard, D.W.3    Greene, W.C.4
  • 25
    • 34249084907 scopus 로고    scopus 로고
    • Inhibition of nuclear factor-κB ameliorates bowel injury and prolongs survival in a neonatal rat model of necrotizing enterocolitis
    • De Plaen, I. G., Liu, S. X., Tian, R., Neequaye, I., May, M. J., Han, X. B., Hsueh, W., Jilling, T., Lu, J., and Caplan, M. S. (2007) Inhibition of nuclear factor-κB ameliorates bowel injury and prolongs survival in a neonatal rat model of necrotizing enterocolitis. Pediatr. Res. 61, 716-721
    • (2007) Pediatr. Res , vol.61 , pp. 716-721
    • De Plaen, I.G.1    Liu, S.X.2    Tian, R.3    Neequaye, I.4    May, M.J.5    Han, X.B.6    Hsueh, W.7    Jilling, T.8    Lu, J.9    Caplan, M.S.10
  • 26
    • 33744792284 scopus 로고    scopus 로고
    • Transforming growth factor β1(TGF-β1) down-regulates TNFβ-induced RANTES production in rheumatoid synovial fibroblasts through NF-κB-mediated transcriptional repression
    • Cho, M. L., Min, S. Y., Chang, S. H., Kim, K. W., Heo, S. B., Lee, S. H., Park, S. H., Cho, C. S., and Kim, H. Y. (2006) Transforming growth factor β1(TGF-β1) down-regulates TNFβ-induced RANTES production in rheumatoid synovial fibroblasts through NF-κB-mediated transcriptional repression. Immunol. Lett. 105, 159-166
    • (2006) Immunol. Lett , vol.105 , pp. 159-166
    • Cho, M.L.1    Min, S.Y.2    Chang, S.H.3    Kim, K.W.4    Heo, S.B.5    Lee, S.H.6    Park, S.H.7    Cho, C.S.8    Kim, H.Y.9
  • 27
    • 79953297943 scopus 로고    scopus 로고
    • Erythropoietin protects intestinal epithelial barrier function and lowers the incidence of experimental neonatal necrotizing enterocolitis
    • Shiou, S. R., Yu, Y., Chen, S., Ciancio, M. J., Petrof, E. O., Sun, J., and Claud, E. C. (2011) Erythropoietin protects intestinal epithelial barrier function and lowers the incidence of experimental neonatal necrotizing enterocolitis. J. Biol. Chem. 286, 12123-12132
    • (2011) J Biol Chem , vol.286 , pp. 12123-12132
    • Shiou, S.R.1    Yu, Y.2    Chen, S.3    Ciancio, M.J.4    Petrof, E.O.5    Sun, J.6    Claud, E.C.7
  • 28
    • 0034604110 scopus 로고    scopus 로고
    • Role of transforming growth factor β in human disease
    • Blobe, G. C., Schiemann, W. P., and Lodish, H. F. (2000) Role of transforming growth factor β in human disease. N. Engl. J. Med. 342, 1350-1358
    • (2000) N. Engl. J. Med , vol.342 , pp. 1350-1358
    • Blobe, G.C.1    Schiemann, W.P.2    Lodish, H.F.3
  • 29
    • 0025222517 scopus 로고
    • The Transforming growth factor-β family
    • Massagué, J. (1990) The Transforming growth factor-β family. Annu. Rev. Cell Biol. 6, 597-641
    • (1990) Annu. Rev. Cell Biol , vol.6 , pp. 597-641
    • Massagué, J.1
  • 32
    • 0036073299 scopus 로고    scopus 로고
    • Differential expression of TGF-β isoforms by normal and inflammatory bowel disease intestinal myofibroblasts
    • McKaig, B. C., Hughes, K., Tighe, P. J., and Mahida, Y. R. (2002) Differential expression of TGF-β isoforms by normal and inflammatory bowel disease intestinal myofibroblasts. Am. J. Physiol. Cell Physiol. 282, C172-C182
    • (2002) Am. J. Physiol. Cell Physiol , vol.282
    • McKaig, B.C.1    Hughes, K.2    Tighe, P.J.3    Mahida, Y.R.4
  • 33
    • 0037592269 scopus 로고    scopus 로고
    • Transforming growth factor-β1 inhibits non-pathogenic Gram negative bacteria-induced NF-κB recruitment to the interleukin-6 gene promoter in intestinal epithelial cells through modulation of histone acetylation
    • Haller, D., Holt, L., Kim, S. C., Schwabe, R. F., Sartor, R. B., and Jobin, C. (2003) Transforming growth factor-β1 inhibits non-pathogenic Gram negative bacteria-induced NF-κB recruitment to the interleukin-6 gene promoter in intestinal epithelial cells through modulation of histone acetylation. J. Biol. Chem. 278, 23851-23860
    • (2003) J. Biol. Chem , vol.278 , pp. 23851-23860
    • Haller, D.1    Holt, L.2    Kim, S.C.3    Schwabe, R.F.4    Sartor, R.B.5    Jobin, C.6
  • 34
    • 3142729969 scopus 로고    scopus 로고
    • TGF-β1 disrupts endotoxin signaling in microglial cells through Smad3 and MAPK pathways
    • Le, Y., Iribarren, P., Gong, W., Cui, Y., Zhang, X., and Wang, J. M. (2004) TGF-β1 disrupts endotoxin signaling in microglial cells through Smad3 and MAPK pathways. J. Immunol. 173, 962-968
    • (2004) J. Immunol , vol.173 , pp. 962-968
    • Le, Y.1    Iribarren, P.2    Gong, W.3    Cui, Y.4    Zhang, X.5    Wang, J.M.6
  • 36
    • 0036152670 scopus 로고    scopus 로고
    • Expression of transforming growth factor β1, transforming growth factor type i and II receptors, and TNF-α in the mucosa of the small intestine in infants with food protein-induced enterocolitis syndrome
    • Chung, H. L., Hwang, J. B., Park, J. J., and Kim, S. G. (2002) Expression of transforming growth factor β1, transforming growth factor type I and II receptors, and TNF-α in the mucosa of the small intestine in infants with food protein-induced enterocolitis syndrome. J. Allergy Clin. Immunol. 109, 150-154
    • (2002) J. Allergy Clin. Immunol , vol.109 , pp. 150-154
    • Chung, H.L.1    Hwang, J.B.2    Park, J.J.3    Kim, S.G.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.