Clinical significance of S100A8 and S100A9 expression in gastric cancer

National Medical Journal of China

Volumn 93, Issue 42, 2013, Pages 3369-3374

  Hu, Ying ^a   Fan, Biao ^a   Zhang, Lian Hai ^a   Cheng, Xiao Jing ^a   Niu, Zhao Jian ^b   Ji, Jia Fu ^a  

^a PEKING UNIVERSITY CANCER HOSPITAL AND INSTITUTE   (China)

^b NONE

Author keywords

Inflammation; Leukocyte L1 antigen complex; S100A8 S100A9; Stomach neoplasms

Indexed keywords

CALGRANULIN A; CALGRANULIN B; HETERODIMER;

ADULT; AGED; ARTICLE; CANCER TISSUE; CELL COUNT; CHRONIC GASTRITIS; CONFOCAL LASER MICROSCOPY; DIMERIZATION; FEMALE; HUMAN; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; INFLAMMATORY CELL; MAJOR CLINICAL STUDY; MALE; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; STOMACH CANCER;

ADULT; AGED; AGED, 80 AND OVER; CALGRANULIN A; CALGRANULIN B; FEMALE; HUMANS; LEUKOCYTE L1 ANTIGEN COMPLEX; MALE; MIDDLE AGED; NEOPLASM STAGING; STOMACH NEOPLASMS;

EID: 84889002555     PISSN: 03762491     EISSN: None     Source Type: Journal    
DOI: 10.3760/cma.j.issn.0376-2491.2013.42.011     Document Type: Article

References (14)

1. Jemal A, Bray F, Center M M, et al. Global cancer statistics. CA Cancer J Clin, 2011, 61: 69-90.
2. Smith D D, Schwarz R R, Schwarz R E. Impact of total lymph node count on staging and survival after gastrectomy for gastric cancer: data from a large US-population database. J Clin Oncol, 2005, 23: 7114-7124.
3. 2005, 85: 2113-2116.
4. Fatourou E, Ziogas D, Baltogiannis G. Moving from lymph node metastasis in gastric cancer to biological markers. World J Surg, 2010, 34: 1140-1141.
5. Kawai H, Minamiya Y, Takahashi N. Prognostic impact of S100A9 overexpression in non-small cell lung cancer. Tumour Biol, 2011, 32: 641-646.
6. Su Y J, Xu F, Yu J P, et al. Up-regulation of the expression of S100A8 and S100A9 in lung adenocarcinoma and its correlation with inflammation and other clinical features. Chin Med J, 2010, 123: 2215-2220.
7. Hermani A, Hess J, De Servi B, et al. Calcium-binding proteins S100A8 and S100A9 as novel diagnostic markers in human prostate cancer. Clin Cancer Res, 2005, 11: 5146-5152.
8. Arai K, Takano S, Teratani T, et al. S100A8 and S100A9 overexpression is associated with poor pathological parameters in invasive ductal carcinoma of the breast. Curr Cancer Drug Targets, 2008, 8: 243-252.
9. Yoo B C, Shin Y K, Lim S B, et al. Evaluation of calgranulin B in stools from the patients with colorectal cancer. Dis Colon Rectum, 2008, 51: 1703-1709.
10. El-Rifai W, Moskaluk C A, Abdrabbo M K, et al. Gastric cancers overexpress S100A calcium-binding proteins. Cancer Res, 2002, 62: 6823-6826.
11. Zhang Y Z, Zhang L H, Gao Y, et al. Discovery and validation of prognostic markers in gastric cancer by genome-wide expression profiling. World J Gastroenterol, 2011, 17: 1710-1717.
12. Ang C W, Nedjadi T, Sheikh A A, et al. Smad4 loss is associated with fewer S100A8-positive monocytes in colorectal tumors and attenuated response to S100A8 in colorectal and pancreatic cancer cells. Carcinogenesis, 2010, 31: 1541-1551.
13. Ito Y, Arai K, Nozawa R, et al. S100A8 and S100A9 expression is a crucial factor for dedifferentiation in thyroid carcinoma. Anticancer Res, 2009, 29: 4157-4161.
14. Sheikh A A, Vimalachandran D, Thompson C C, et al. The expression of S100A8 in pancreatic cancer-associated monocytes is associated with the Smad4 status of pancreatic cancer cells. Proteomics, 2007, 7: 1929-1940.