Optically induced occlusion of single blood vessels in rodent neocortex

Cold Spring Harbor Protocols

Volumn 2013, Issue 12, 2013, Pages 1153-1160

  Shih, Andy Y ^a   Nishimura, Nozomi ^a   Nguyen, John ^a   Friedman, Beth ^a   Lyden, Patrick D ^a   Schaffer, Chris B ^a   Kleinfeld, David ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL OCCLUSION; BRAIN CORTEX; BRAIN ISCHEMIA; CLINICAL PROTOCOL; DIAGNOSTIC IMAGING; HISTOLOGY; NONHUMAN; OPTICS; PHOTOTHROMBOTIC OCCLUSION; PLASMA MEDIATED OCCLUSION; POST HOC ANALYSIS; RAT; ANIMAL MODEL; BLOOD CLOTTING; EXPERIMENTAL THROMBOSIS; MULTIPHOTON MICROSCOPY; NEOCORTEX; NEUROIMAGING;

ANIMALS; BLOOD VESSELS; HEMOSTATIC TECHNIQUES; LIGHT; NEOCORTEX; PHOTOSENSITIZING AGENTS; RODENTIA;

PHOTOSENSITIZING AGENT;

EID: 84888992794     PISSN: 19403402     EISSN: 15596095     Source Type: Journal    
DOI: 10.1101/pdb.prot079509     Document Type: Article

References (34)

1. Blinder P., Shih AY, Rafie C, Kleinfeld D. 2010. Topological basis for the robust distribution of blood to rodent neocortex. Proc Natl Acad Sci 107: 12670-12675.
2. Brown CE., Li P, Boyd JD, Delaney KR, Murphy TH. 2007. Extensive turnover of dendritic spines and vascular remodeling in cortical tissues recovering from stroke. J Neurosci 27: 4101-4109.
3. 2+signaling in vivo. Glia 57: 767-776.
4. Drew PJ., Shih AY, Driscoll JD, Knutsen PM, Blinder P, Davalos D, Akassoglou K, Tsai P, Kleinfeld D. 2010. Chronic optical access through a polished and reinforced thinned skull. Nature Methods 7: 981-984.
5. Feng G., Mellor RH, Bernstein M, Keller-Peck C, Nguyen QT, Wallace M, Nerbonne JM., Lichtman JW, Sanes JR. 2000. Imaging neuronal subsets in transgenic mice expressing multiple spectral variants of GFP. Neuron 28: 41-51.
6. Ginsberg MD., Busto R. 1989. Rodent models of cerebral ischemia. Stroke 20: 1627-1642.
7. Holtmaat A., Bonhoeffer T, Chow DK, Chuckowree J, De Paola V, Hofer SB, Hübener M., Keck T, Knott G, Lee WC, et al. 2009. Long-term, highresolution imaging in the mouse neocortex through a chronic cranial window. Nat Protoc 4: 1128-1144.
8. Kleinfeld D., Delaney KR. 1996. Distributed representation of vibrissa movement in the upper layers of somatosensory cortex revealed with voltage sensitive dyes. J Comp Neurol 375: 89-108.
9. Kleinfeld D., Denk W. 2000. Two-photon imaging of neocortical microcirculation. In Imaging neurons: A laboratory manual (ed. Yuste R, et al.), pp. 23.1-23.15. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
10. Kleinfeld D., Mitra PP, Helmchen F, Denk W. 1998. Fluctuations and stimulus-induced changes in blood flow observed in individual capillaries in layers 2 through 4 of rat neocortex. Proc Natl Acad Sci 95: 15741-15746.
11. Kleinfeld D., Friedman B, Lyden PD, Shih AY. 2008. Targeted occlusion to surface and deep vessels in neocortex via linear and nonlinear optical absorption. In Animal models of acute neurological injuries (ed. Chen J, et al.), pp. 169-185. Humana Press, Totowa, NJ.
12. Kovari E., Gold G, Herrmann FR, Canuto A, Hof PR, Michel JP, Bouras C, Giannakopoulos P. 2004. Cortical microinfarcts and demyelination significantly affect cognition in brain aging. Stroke 35: 410-414.
13. Majewska A., Yiu G, Yuste R. 2000. A custom-made two-photon microscope and deconvolution system. Pflügers Arch 441: 398-408.
14. Misgeld T., Kerschensteiner M. 2006. In vivo imaging of the diseased nervous system. Nat Rev Neurosci 7: 449-463.
15. Nguyen Q-T., Tsai PS, Kleinfeld D. 2006. MPScope: A versatile software suite for multiphoton microscopy. J Neurosci Methods 156: 351-359.
16. Nguyen J., Nishimura N, Iadecola C, Schaffer CB. 2007. Single venule occlusions induced by photodisruption using femtosecond laser pulses cause decreased blood flow in rat cortex. In Society for neuroscience. Society for Neuroscience, San Diego.
17. Nguyen Q-T., Dolnick EM, Driscoll J, Kleinfeld D. 2009. MPScope 2.0: A computer system for two-photon laser scanning microscopy with concurrent plasma-mediated ablation and electrophysiology. In Methods for in vivo optical imaging, 2nd ed. (ed. Frostig RD), pp. 117-142. CRC Press, Boca Raton, FL.
18. Nishimura N., Schaffer CB, Friedman B, Tsai PS, Lyden PD, Kleinfeld D. 2006. Targeted insult to individual subsurface cortical blood vessels using ultrashort laser pulses: Three models of stroke. Nat Methods 3: 99-108.
19. Nishimura N., Schaffer CB, Friedman B, Lyden PD, Kleinfeld D. 2007. Penetrating arterioles are a bottleneck in the perfusion of neocortex. Proc Natl Acad Sci 104: 365-370.
20. Nishimura N., Rosidi NL, Iadecola C, Schaffer CB. 2010. Limitations of collateral flow after occlusion of a single cortical penetrating arteriole. J Cereb Blood Flow Metab 30: 1914-1927.
21. Schaffer CB., Brodeur A, Mazur E. 2001. Laser-induced breakdown and damage in bulk transparent materials induced by tightly-focused femtosecond laser pulses. Meas Sci Technol 12: 1784-1794.
22. Schaffer CB., Friedman B, Nishimura N, Schroeder LF, Tsai PS, Ebner FF, Lyden PD., Kleinfeld D. 2006. Two-photon imaging of cortical surface microvessels reveals a robust redistribution in blood flow after vascular occlusion. PLoS Biol 4: e22. doi: 10.1371/journal.pbio.0040022.
23. Shih AY., Friedman B, Drew PJ, Tsai PS, Lyden PD, Kleinfeld D. 2009. Active dilation of penetrating arterioles restores red blood cell flux to penumbral neocortex after focal stroke. J Cereb Blood Flow Metab 29: 738-751.
24. Sigler A., Goroshkov A, Murphy TH. 2008. Hardware and methodology for targeting single brain arterioles for photothrombotic stroke on an upright microscope. J Neurosci Methods 170: 35-44.
25. Stosiek C., Garaschuk O, Holthoff K, Konnerth A. 2003. In vivo two-photon calcium imaging of neuronal networks. Proc Natl Acad Sci 100: 7319-7324.
26. Suter OC., Sunthorn T, Kraftsik R, Straubel J, Darekar P, Khalili K, Miklossy J. 2002. Cerebral hypoperfusion generates cortical watershed microinfarcts in Alzheimer disease. Stroke 33: 1986-1992.
27. Tsai PS., Kleinfeld D. 2009. In vivo two-photon laser scanning microscopy with concurrent plasma-mediated ablation: Principles and hardware realization. In Methods for in vivo optical imaging, 2nd ed. (ed. Frostig RD), pp. 59-115. CRC Press, Boca Raton, FL.
28. Tsai PS., Friedman B, Squier JA, Kleinfeld D. 2004. Ultrashort pulsed laser light: A cool tool for ultraprecise cutting of tissue and cells. Optics & Photonic News 14: 24-29.
29. Tsai PS., Friedman B, Schaffer CB, Squier JA, Kleinfeld D. 2005. All-optical, in situ histology of neuronal tissue with femtosecond laser pulses. In Imaging in neuroscience and development: A laboratory manual (ed. Yuste R., Konnerth A), pp. 815-826. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
30. Tsai PS, Blinder P, Migliori BJ, Neev J, Jin Y, Squier JA, Kleinfeld D. 2009. Plasma-mediated ablation: An optical tool for submicrometer surgery on neuronal and vascular systems. Curr Opin Biotechnol 20: 90-99.
31. Watson BD., Dietrich WD, Busto R, Wachtel MS, Ginsberg MD. 1985. Induction of reproducible brain infarction by photochemically initiated thrombosis. Ann Neurol 17: 497-504.
32. Watson BD., Prado R, Veloso A, Brunschwig JP, Dietrich WD. 2002. Cerebral blood flow restoration and reperfusion injury after ultraviolet laserfacilitated middle cerebral artery recanalization in rat thrombotic stroke. Stroke 33: 428-434.
33. Xu HT., Pan F, Yang G, Gan WB. 2007. Choice of cranial window type for in vivo imaging affects dendritic spine turnover in the cortex. Nat Neurosci 10: 549-551.
34. Zhang S., Boyd J, Delaney KR, Murphy TH. 2005. Rapid reversible changes in dendritic spine structure in vivo gated by the degree of ischemia. J Neurosci 25: 5333-5338.