Targeted disruption of Shp2 in chondrocytes leads to metachondromatosis with multiple cartilaginous protrusions

Journal of Bone and Mineral Research

Volumn 29, Issue 3, 2014, Pages 761-769

  Kim, Harry K W ^a,b   Feng, Gen Sheng ^c   Chen, Di ^d   King, Philip D ^e   Kamiya, Nobuhiro ^a,b  

^a TEXAS SCOTTISH RITE HOSPITAL FOR CHILDREN   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d RUSH UNIVERSITY MEDICAL CENTER   (United States)

^e UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

cartilage specific knock out mouse; enchondroma; exostosis; metachondromatosis; SHP2

Indexed keywords

CARTILAGE-SPECIFIC KNOCK-OUT MOUSE; ENCHONDROMA; EXOSTOSIS; METACHONDROMATOSIS; SHP2;

ANIMALS; BONE NEOPLASMS; CARTILAGE; CHONDROCYTES; CHONDROMATOSIS; EXOSTOSES, MULTIPLE HEREDITARY; MAP KINASE SIGNALING SYSTEM; MICE; MICE, KNOCKOUT; REAL-TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SRC HOMOLOGY DOMAINS;

EID: 84888875580     PISSN: 08840431     EISSN: 15234681     Source Type: Journal    
DOI: 10.1002/jbmr.2062     Document Type: Article

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