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Bioorganic and Medicinal Chemistry Letters

Volumn 23, Issue 24, 2013, Pages 6789-6793

Discovery of a potent respiratory syncytial virus RNA polymerase inhibitor

(13) Xiong, Hui a Foulk, Melinda a Aschenbrenner, Lisa a Fan, Jun a Tiong Yip, Choi Lai a Johnson, Kenneth D a Moustakas, Demetri a Fleming, Paul R a Brown, Dean G a Zhang, Minli a Ferguson, Douglas a Wu, Dedong a Yu, Qin a

a ASTRAZENECA (United Kingdom)

Author keywords

Antiviral; Polymerase inhibitor; Respiratory syncytial virus

Indexed keywords

ANTIVIRUS AGENT; AZEPINE DERIVATIVE; BENZOTHIENOAZEPINE; PYRIDINE; RNA POLYMERASE; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIVIRAL ACTIVITY; ARTICLE; CYTOTOXICITY; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; HEP 2 CELL; NONHUMAN; RAT; RESPIRATORY SYNCYTIAL PNEUMOVIRUS;

RESPIRATORY SYNCYTIAL VIRUS; RICE STRIPE VIRUS;

ANTIVIRAL; POLYMERASE INHIBITOR; RESPIRATORY SYNCYTIAL VIRUS;

ANTIVIRAL AGENTS; AZEPINES; CELL LINE; DNA-DIRECTED RNA POLYMERASES; DRUG EVALUATION, PRECLINICAL; ENZYME ACTIVATION; ENZYME INHIBITORS; HUMANS; RESPIRATORY SYNCYTIAL VIRUSES; STRUCTURE-ACTIVITY RELATIONSHIP; VIRAL PROTEINS; VIRUS REPLICATION;

EID: 84888871269 PISSN: 0960894X EISSN: 14643405 Source Type: Journal
DOI: 10.1016/j.bmcl.2013.10.018 Document Type: Article

Times cited : (38)

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