메뉴 건너뛰기




Volumn 369, Issue 1633, 2014, Pages

Hippocampal NMDA receptors are important for behavioural inhibition but not for encoding associative spatial memories

Author keywords

Hippocampus; Long term potentiation; NMDAR; Spatial learning; Synaptic plasticity; Watermaze

Indexed keywords

BEHAVIORAL RESPONSE; BRAIN; INHIBITION; LEARNING; MEMORY; NEUROLOGY; RODENT;

EID: 84888798017     PISSN: 09628436     EISSN: 14712970     Source Type: Journal    
DOI: 10.1098/rstb.2013.0149     Document Type: Article
Times cited : (38)

References (43)
  • 2
    • 0015799240 scopus 로고
    • Long-lasting potentiation of synaptic transmission in the dentate area of the anaesthetized rabbit following stimulation of the perforant path
    • Bliss TV, Lomo T. 1973 Long-lasting potentiation of synaptic transmission in the dentate area of the anaesthetized rabbit following stimulation of the perforant path. J. Physiol. 232, 331-356.
    • (1973) J. Physiol. , vol.232 , pp. 331-356
    • Bliss, T.V.1    Lomo, T.2
  • 3
    • 0027476024 scopus 로고
    • A synaptic model of memory: Long-term potentiation in the hippocampus
    • (doi:10.1038/ 361031a0)
    • Bliss TV, Collingridge GL. 1993 A synaptic model of memory: long-term potentiation in the hippocampus. Nature 361, 31-39. (doi:10.1038/ 361031a0)
    • (1993) Nature , vol.361 , pp. 31-39
    • Bliss, T.V.1    Collingridge, G.L.2
  • 4
    • 0034042406 scopus 로고    scopus 로고
    • Synaptic plasticity and memory: An evaluation of the hypothesis
    • (doi:10.1146/annurev.neuro.23.1.649)
    • Martin SJ, Grimwood PD, Morris RG. 2000 Synaptic plasticity and memory: an evaluation of the hypothesis. Annu. Rev. Neurosci. 23, 649-711. (doi:10.1146/annurev.neuro.23.1.649)
    • (2000) Annu. Rev. Neurosci. , vol.23 , pp. 649-711
    • Martin, S.J.1    Grimwood, P.D.2    Morris, R.G.3
  • 6
    • 0030446363 scopus 로고    scopus 로고
    • The essential role of hippocampal CA1 NMDA receptor-dependent synaptic plasticity in spatial memory
    • (doi:10.1016/S0092-8674(00)81827-9)
    • Tsien JZ, Huerta PT, Tonegawa S. 1996 The essential role of hippocampal CA1 NMDA receptor-dependent synaptic plasticity in spatial memory. Cell 87, 1327-1338. (doi:10.1016/S0092-8674(00)81827-9)
    • (1996) Cell , vol.87 , pp. 1327-1338
    • Tsien, J.Z.1    Huerta, P.T.2    Tonegawa, S.3
  • 7
    • 77958569164 scopus 로고    scopus 로고
    • A role for calcium-permeable AMPA receptors in synaptic plasticity and learning
    • (doi:10.1371/journal.pone.0012818)
    • Wiltgen BJ et al. 2010 A role for calcium-permeable AMPA receptors in synaptic plasticity and learning. PLoS ONE 5, e12818. (doi:10.1371/journal.pone.0012818)
    • (2010) PLoS ONE , vol.5
    • Wiltgen, B.J.1
  • 8
    • 57049114322 scopus 로고    scopus 로고
    • Removal of FKBP12 enhances mTOR-Raptor interactions, LTP, memory, and perseverative/repetitive behavior
    • (doi:10.1016/j.neuron.2008.09.037)
    • Hoeffer CA et al. 2008 Removal of FKBP12 enhances mTOR-Raptor interactions, LTP, memory, and perseverative/repetitive behavior. Neuron 60, 832-845. (doi:10.1016/j.neuron.2008.09.037)
    • (2008) Neuron , vol.60 , pp. 832-845
    • Hoeffer, C.A.1
  • 9
    • 0344519489 scopus 로고    scopus 로고
    • Retention of NMDA receptor NR2 subunits in the lumen of endoplasmic reticulum in targeted NR1 knockout mice
    • (doi:10.1073/pnas.0830996100)
    • Fukaya M, Kato A, Lovett C, Tonegawa S, Watanabe M. 2003 Retention of NMDA receptor NR2 subunits in the lumen of endoplasmic reticulum in targeted NR1 knockout mice. Proc. Natl Acad. Sci. USA 100, 4855-4860. (doi:10.1073/pnas.0830996100)
    • (2003) Proc. Natl Acad. Sci. USA , vol.100 , pp. 4855-4860
    • Fukaya, M.1    Kato, A.2    Lovett, C.3    Tonegawa, S.4    Watanabe, M.5
  • 10
    • 77950665251 scopus 로고    scopus 로고
    • Loss of GluN2B-containing NMDA receptors in CA1 hippocampus and cortex impairs long-term depression, reduces dendritic spine density, and disrupts learning
    • (doi:10.1523/JNEUROSCI.0640-10.2010)
    • Brigman JL et al. 2010 Loss of GluN2B-containing NMDA receptors in CA1 hippocampus and cortex impairs long-term depression, reduces dendritic spine density, and disrupts learning. J. Neurosci. 30, 4590-4600. (doi:10.1523/JNEUROSCI.0640-10.2010)
    • (2010) J. Neurosci. , vol.30 , pp. 4590-4600
    • Brigman, J.L.1
  • 11
    • 33646082742 scopus 로고    scopus 로고
    • Impaired sequential egocentric and allocentric memories in forebrainrstb. specific-NMDA receptor knock-out mice during a new task dissociating strategies of navigation
    • (doi:10.1523/ JNEUROSCI.3408-05.2006)
    • Rondi-Reig L et al. 2006 Impaired sequential egocentric and allocentric memories in forebrainrstb. specific-NMDA receptor knock-out mice during a new task dissociating strategies of navigation. J. Neurosci. 26, 4071-4081. (doi:10.1523/ JNEUROSCI.3408-05.2006)
    • (2006) J. Neurosci. , vol.26 , pp. 4071-4081
    • Rondi-Reig, L.1
  • 12
    • 84864493623 scopus 로고    scopus 로고
    • Dissecting spatial knowledge from spatial choice by hippocampal NMDA receptor deletion
    • (doi:10.1038/nn.3166)
    • Bannerman DM et al. 2012 Dissecting spatial knowledge from spatial choice by hippocampal NMDA receptor deletion. Nat. Neurosci. 15, 1153-1159. (doi:10.1038/nn.3166)
    • (2012) Nat. Neurosci. , vol.15 , pp. 1153-1159
    • Bannerman, D.M.1
  • 13
    • 0024455878 scopus 로고
    • Synaptic plasticity and learning: Selective impairment of learning rats and blockade of long-term potentiation in vivo by the N-methyl-D-aspartate receptor antagonist AP5
    • Morris RG. 1989 Synaptic plasticity and learning: selective impairment of learning rats and blockade of long-term potentiation in vivo by the N-methyl-D-aspartate receptor antagonist AP5. J. Neurosci. 9, 3040-3057.
    • (1989) J. Neurosci. , vol.9 , pp. 3040-3057
    • Morris, R.G.1
  • 14
    • 0022650213 scopus 로고
    • Selective impairment of learning and blockade of long-term potentiation by an N-methyl-D-aspartate receptor antagonist, AP5
    • (doi:10.1038/319774a0)
    • Morris RG, Anderson E, Lynch GS, Baudry M. 1986 Selective impairment of learning and blockade of long-term potentiation by an N-methyl-D-aspartate receptor antagonist, AP5. Nature 319, 774-776. (doi:10.1038/319774a0)
    • (1986) Nature , vol.319 , pp. 774-776
    • Morris, R.G.1    Anderson, E.2    Lynch, G.S.3    Baudry, M.4
  • 15
    • 0028828225 scopus 로고
    • Distinct components of spatial learning revealed by prior training and NMDA receptor blockade
    • (doi:10. 1038/378182a0)
    • Bannerman DM, Good MA, Butcher SP, Ramsay M, Morris RGM. 1995 Distinct components of spatial learning revealed by prior training and NMDA receptor blockade. Nature 378, 182-186. (doi:10. 1038/378182a0)
    • (1995) Nature , vol.378 , pp. 182-186
    • Bannerman, D.M.1    Good, M.A.2    Butcher, S.P.3    Ramsay, M.4    Morris, R.G.M.5
  • 16
    • 0028868560 scopus 로고
    • Spatial learning without NMDA receptor-dependent long-term potentiation
    • (doi:10.1038/378186a0)
    • Saucier D, Cain DP. 1995 Spatial learning without NMDA receptor-dependent long-term potentiation. Nature 378, 186-189. (doi:10.1038/378186a0)
    • (1995) Nature , vol.378 , pp. 186-189
    • Saucier, D.1    Cain, D.P.2
  • 17
    • 84874543548 scopus 로고    scopus 로고
    • Upstairs/ downstairs revisited: Spatial pretraining-induced rescue of normal spatial learning during selective blockade of hippocampal N-methyl-D-aspartate receptors
    • (doi:10. 1111/ejn.12087)
    • Inglis J, Martin SJ, Morris RG. 2013 Upstairs/ downstairs revisited: spatial pretraining-induced rescue of normal spatial learning during selective blockade of hippocampal N-methyl-D-aspartate receptors. Eur. J. Neurosci. 37, 718-727. (doi:10. 1111/ejn.12087)
    • (2013) Eur. J. Neurosci. , vol.37 , pp. 718-727
    • Inglis, J.1    Martin, S.J.2    Morris, R.G.3
  • 18
    • 84874511951 scopus 로고    scopus 로고
    • N-methyl-D-aspartate receptors, learning and memory: Chronic intraventricular infusion of the NMDA receptor antagonist d-AP5 interacts directly with the neural mechanisms of spatial learning
    • (doi:10.1111/ejn.12086)
    • Morris RG, Steele RJ, Bell JE, Martin SJ. 2013 N-methyl-D-aspartate receptors, learning and memory: chronic intraventricular infusion of the NMDA receptor antagonist d-AP5 interacts directly with the neural mechanisms of spatial learning. Eur. J. Neurosci. 37, 700-717. (doi:10.1111/ejn.12086)
    • (2013) Eur. J. Neurosci. , vol.37 , pp. 700-717
    • Morris, R.G.1    Steele, R.J.2    Bell, J.E.3    Martin, S.J.4
  • 19
    • 66349130530 scopus 로고    scopus 로고
    • Pretraining does not ameliorate spatial learning deficits induced by intrahippocampal infusion of AP5
    • (doi:10.1037/a0015672)
    • Uekita T, Okaichi H. 2009 Pretraining does not ameliorate spatial learning deficits induced by intrahippocampal infusion of AP5. Behav. Neurosci. 123, 520-526. (doi:10.1037/a0015672)
    • (2009) Behav. Neurosci. , vol.123 , pp. 520-526
    • Uekita, T.1    Okaichi, H.2
  • 20
    • 0025716058 scopus 로고
    • Hippocampal synaptic plasticity and NMDA receptors: A role in information storage?
    • (doi:10.1098/rstb.1990.0164)
    • Morris RG, Davis S, Butcher SP. 1990 Hippocampal synaptic plasticity and NMDA receptors: a role in information storage? Phil. Trans. R. Soc. Lond. B 329, 187-204. (doi:10.1098/rstb.1990.0164)
    • (1990) Phil. Trans. R. Soc. Lond. B , vol.329 , pp. 187-204
    • Morris, R.G.1    Davis, S.2    Butcher, S.P.3
  • 21
    • 0024988849 scopus 로고
    • Why NMDA receptordependent long-term potentiation may not be a mechanism of learning and memory: Re-appraisal of the NMDA receptor blockade strategy
    • Keith JR, Rudy JW. 1990 Why NMDA receptordependent long-term potentiation may not be a mechanism of learning and memory: re-appraisal of the NMDA receptor blockade strategy. Psychobiology 18, 251-257.
    • (1990) Psychobiology , vol.18 , pp. 251-257
    • Keith, J.R.1    Rudy, J.W.2
  • 22
    • 0030057656 scopus 로고    scopus 로고
    • Detailed behavioral analysis of water maze acquisition under APV or CNQX: Contribution of sensorimotor disturbances to drug-induced acquisition deficits
    • (doi:10.1037/0735-7044.110.1.86)
    • Cain DP, Saucier D, Hall J, Hargreaves EL, Boon F. 1996 Detailed behavioral analysis of water maze acquisition under APV or CNQX: contribution of sensorimotor disturbances to drug-induced acquisition deficits. Behav. Neurosci. 110, 86-102. (doi:10.1037/0735-7044.110.1.86)
    • (1996) Behav. Neurosci. , vol.110 , pp. 86-102
    • Cain, D.P.1    Saucier, D.2    Hall, J.3    Hargreaves, E.L.4    Boon, F.5
  • 23
    • 0002534681 scopus 로고
    • Functional organisation of the limbic system in the process of registration of information: Facts and hypotheses
    • In (ed. RIIKH Pribram), New York, NY: Plenum Press
    • Vinogradova OS. 1975 Functional organisation of the limbic system in the process of registration of information: facts and hypotheses. In The hippocampus (ed. RIIKH Pribram), pp. 3-69. New York, NY: Plenum Press.
    • (1975) The hippocampus , pp. 3-69
    • Vinogradova, O.S.1
  • 26
    • 0034255146 scopus 로고    scopus 로고
    • Learning about pain: The neural substrate of the prediction error for aversive events
    • (doi:10.1073/pnas.160266497)
    • Ploghaus A, Tracey I, Clare S, Gati JS, Rawlins JNP, Matthews PM. 2000 Learning about pain: the neural substrate of the prediction error for aversive events. Proc. Natl Acad. Sci. USA 97, 9281-9286. (doi:10.1073/pnas.160266497)
    • (2000) Proc. Natl Acad. Sci. USA , vol.97 , pp. 9281-9286
    • Ploghaus, A.1    Tracey, I.2    Clare, S.3    Gati, J.S.4    Rawlins, J.N.P.5    Matthews, P.M.6
  • 27
    • 34547903594 scopus 로고    scopus 로고
    • Match mismatch processes underlie human hippocampal responses to associative novelty
    • (doi:10.1523/JNEUROSCI.1677-07.2007)
    • Kumaran D, Maguire EA. 2007 Match mismatch processes underlie human hippocampal responses to associative novelty. J. Neurosci. 27, 8517-8524. (doi:10.1523/JNEUROSCI.1677-07.2007)
    • (2007) J. Neurosci. , vol.27 , pp. 8517-8524
    • Kumaran, D.1    Maguire, E.A.2
  • 28
    • 33845482744 scopus 로고    scopus 로고
    • An unexpected sequence of events: Mismatch detection in the human hippocampus
    • (doi:10. 1371/journal.pbio.0040424)
    • Kumaran D, Maguire EA. 2006 An unexpected sequence of events: mismatch detection in the human hippocampus. PLoS Biol. 4, e424. (doi:10. 1371/journal.pbio.0040424)
    • (2006) PLoS Biol. , vol.4
    • Kumaran, D.1    Maguire, E.A.2
  • 30
    • 0017126949 scopus 로고
    • Place units in the hippocampus of the freely moving rat
    • (doi:10.1016/0014-4886(76)90055-8)
    • O'Keefe J. 1976 Place units in the hippocampus of the freely moving rat. Exp. Neurol. 51, 78-109. (doi:10.1016/0014-4886(76)90055-8)
    • (1976) Exp. Neurol. , vol.51 , pp. 78-109
    • O'Keefe, J.1
  • 31
    • 0036685549 scopus 로고    scopus 로고
    • Hippocampal neurons responding to first-time dislocation of a target object
    • (doi:10.1016/S0896-6273(02)00784-5)
    • Fyhn M, Molden S, Hollup S, Moser M-B, Moser EI. 2002 Hippocampal neurons responding to first-time dislocation of a target object. Neuron 35, 555-566. (doi:10.1016/S0896-6273(02)00784-5)
    • (2002) Neuron , vol.35 , pp. 555-566
    • Fyhn, M.1    Molden, S.2    Hollup, S.3    Moser, M.-B.4    Moser, E.I.5
  • 32
    • 0032521351 scopus 로고    scopus 로고
    • Hippocampal lesions disrupt an associative mismatch process
    • Honey RC, Watt A, Good M. 1998 Hippocampal lesions disrupt an associative mismatch process. J. Neurosci. 18, 2226-2230.
    • (1998) J. Neurosci. , vol.18 , pp. 2226-2230
    • Honey, R.C.1    Watt, A.2    Good, M.3
  • 33
    • 33644688754 scopus 로고    scopus 로고
    • Dopamine neurons report an error in the temporal prediction of reward during learning
    • (doi:10.1038/1124)
    • Hollerman JR, Schultz W. 1998 Dopamine neurons report an error in the temporal prediction of reward during learning. Nat. Neurosci. 1, 304-309. (doi:10.1038/1124)
    • (1998) Nat. Neurosci. , vol.1 , pp. 304-309
    • Hollerman, J.R.1    Schultz, W.2
  • 34
    • 19544370227 scopus 로고    scopus 로고
    • The hippocampal-VTA loop: Controlling the entry of information into long-term memory
    • (doi:10. 1016/j.neuron.2005.05.002)
    • Lisman JE, Grace AA. 2005 The hippocampal-VTA loop: controlling the entry of information into long-term memory. Neuron 46, 703-713. (doi:10. 1016/j.neuron.2005.05.002)
    • (2005) Neuron , vol.46 , pp. 703-713
    • Lisman, J.E.1    Grace, A.A.2
  • 35
    • 33745072128 scopus 로고    scopus 로고
    • Elements of a neurobiological theory of hippocampal function: The role of synaptic plasticity, synaptic tagging and schemas
    • (doi:10.1111/j. 1460-9568.2006.04888.x)
    • Morris RG. 2006 Elements of a neurobiological theory of hippocampal function: the role of synaptic plasticity, synaptic tagging and schemas. Eur. J. Neurosci. 23, 2829-2846. (doi:10.1111/j. 1460-9568.2006.04888.x)
    • (2006) Eur. J. Neurosci. , vol.23 , pp. 2829-2846
    • Morris, R.G.1
  • 36
    • 0037987979 scopus 로고    scopus 로고
    • Hippocampal CA3 NMDA receptors are crucial for memory acquisition of one-time experience
    • (doi:10.1016/S0896-6273(03)00165-X)
    • Nakazawa K, Sun LD, Quirk MC, Rondi-Reig L, Wilson MA, Tonegawa S. 2003 Hippocampal CA3 NMDA receptors are crucial for memory acquisition of one-time experience. Neuron 38, 305-315. (doi:10.1016/S0896-6273(03)00165-X)
    • (2003) Neuron , vol.38 , pp. 305-315
    • Nakazawa, K.1    Sun, L.D.2    Quirk, M.C.3    Rondi-Reig, L.4    Wilson, M.A.5    Tonegawa, S.6
  • 37
    • 0032891813 scopus 로고    scopus 로고
    • Delay-dependent impairment of a matching-to-place task with chronic and intrahippocampal infusion of the NMDA-antagonist D-AP5
    • (doi:10.1002/(SICI)1098-1063(1999)9: 2,118::AID-HIPO4.3.0.CO;2-8)
    • Steele RJ, Morris RG. 1999 Delay-dependent impairment of a matching-to-place task with chronic and intrahippocampal infusion of the NMDA-antagonist D-AP5. Hippocampus 9, 118-136. (doi:10.1002/(SICI)1098-1063(1999)9: 2,118::AID-HIPO4.3.0.CO;2-8)
    • (1999) Hippocampus , vol.9 , pp. 118-136
    • Steele, R.J.1    Morris, R.G.2
  • 39
    • 33847228347 scopus 로고    scopus 로고
    • Hippocampal long-term depression: Master or minion in declarative memory processes?
    • (doi:10.1016/j.tins.2007.01.002)
    • Kemp A, Manahan-Vaughan D. 2007 Hippocampal long-term depression: master or minion in declarative memory processes? Trends Neurosci. 30, 111-118. (doi:10.1016/j.tins.2007.01.002)
    • (2007) Trends Neurosci. , vol.30 , pp. 111-118
    • Kemp, A.1    Manahan-Vaughan, D.2
  • 41
    • 70649109843 scopus 로고    scopus 로고
    • Hippocampal NMDA receptors and anxiety: At the interface between cognition and emotion
    • (doi:10.1016/j.ejphar.2009.10.014)
    • Barkus C, McHugh SB, Sprengel R, Seeburg PH, Rawlins JNP, Bannerman DM. 2010 Hippocampal NMDA receptors and anxiety: at the interface between cognition and emotion. Eur. J. Pharmacol. 626, 49-56. (doi:10.1016/j.ejphar.2009.10.014)
    • (2010) Eur. J. Pharmacol. , vol.626 , pp. 49-56
    • Barkus, C.1    McHugh, S.B.2    Sprengel, R.3    Seeburg, P.H.4    Rawlins, J.N.P.5    Bannerman, D.M.6
  • 42
    • 57049147406 scopus 로고    scopus 로고
    • Contribution of hippocampal and extra-hippocampal NR2Bcontaining NMDA receptors to performance on spatial learning tasks
    • (doi:10.1016/j.neuron.2008.09.039)
    • von Engelhardt J et al. 2008 Contribution of hippocampal and extra-hippocampal NR2Bcontaining NMDA receptors to performance on spatial learning tasks. Neuron 60, 846-860. (doi:10.1016/j.neuron.2008.09.039)
    • (2008) Neuron , vol.60 , pp. 846-860
    • von Engelhardt, J.1
  • 43
    • 84859428675 scopus 로고    scopus 로고
    • GluN1 hypomorph mice exhibit wide-ranging behavioral alterations
    • (doi:10.1111/j.1601-183X.2012.00767.x)
    • Barkus C, Dawson LA, Sharp T, Bannerman DM. 2012 GluN1 hypomorph mice exhibit wide-ranging behavioral alterations. Genes Brain Behav. 11, 342-351. (doi:10.1111/j.1601-183X.2012.00767.x)
    • (2012) Genes Brain Behav. , vol.11 , pp. 342-351
    • Barkus, C.1    Dawson, L.A.2    Sharp, T.3    Bannerman, D.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.