Histopathological and biomechanical parameters of repaired rat Achilles tendons treated with and without mannose-6-phosphate

Biomedical Sciences Instrumentation

Volumn 48, Issue , 2012, Pages

  Black, David A ^a   Tucci, Michelle ^a   Puckett, Aaron ^a   Benghuzzi, Hamed ^a  

^a UNIVERSITY OF MISSISSIPPI MEDICAL CENTER   (United States)

Author keywords

Adhesion; Healing; Mannose 6 phosphate; Tendon

Indexed keywords

ADHESION; BIOMECHANICS; CELL CULTURE; ELASTIN; GLYCOPROTEINS; RATS; REPAIR;

ACHILLES TENDONS; BIOMECHANICAL ANALYSIS; BIOMECHANICAL PARAMETERS; CROSS SECTIONAL AREA; ELASTIN PRODUCTION; HEALING; MANNOSE 6 PHOSPHATES; SPRAGUE-DAWLEY RATS;

TENDONS;

ELASTIN; MANNOSE 6 PHOSPHATE;

ACHILLES TENDON; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOMECHANICS; CALLUS; CONTROLLED STUDY; DOWN REGULATION; HISTOPATHOLOGY; MECHANICAL STRESS; MECHANICAL TORSION; NONHUMAN; PROTEIN SYNTHESIS; RAT; SCAR FORMATION; TENDON RECONSTRUCTION; WOUND HEALING; YOUNG MODULUS;

EID: 84888624930     PISSN: 00678856     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (10)

1. Ghahary, A., et al., Cellular response to latent TGF-beta1 is facilitated by insulin-like growth factor-II/mannose-6-phosphate receptors on MS-9 cells. Exp Cell Res, 1999. 251(1): p. 111-20.
2. Clavel, C., et al., Synthesis and biological activity of M6-P and M6-P analogs on fibroblast and keratinocyte proliferation. Farmaco, 2005. 60(9): p. 721-5.
3. Black, D.A., et al., Effects of mannose-6-phosphate on human fibroblast cells-biomed 2010. Biomed Sci Instrum, 2010. 46: p. 196-201.
4. Haung, D., et al., Defining the role of hif-1? And ctgf in fibrosis-biomed 2009. Biomed Sci Instrum, 2009. 45: p. 340-5.
5. Black, D.A., et al., A new model for repair of the achilles tendon in the rat. J Invest Surg, 2011. 24(5): p. 217-21.
6. Black, D.A., et al., Strength of a new method of achilles tendon repair in the rat-biomed 2011. Biomed Sci Instrum, 2011. 47: p. 112-7.
7. Sonnylal, S., et al., Selective expression of connective tissue growth factor in fibroblasts in vivo promotes systemic tissue fibrosis. Arthritis Rheum, 2010. 62(5): p. 1523-32.
8. Ihn, H., Pathogenesis of fibrosis: role of TGF-beta and CTGF. Curr Opin Rheumatol, 2002. 14(6): p. 681-5.
9. Ghahary, A., E.E. Tredget, and Q. Shen, Insulin-like growth factor-II/mannose 6 phosphate receptors facilitate the matrix effects of latent transforming growth factor-beta1 released from genetically modified keratinocytes in a fibroblast/keratinocyte co-culture system. J Cell Physiol, 1999. 180(1): p. 61-70.
10. Bates, S.J., et al., Mannose-6-phosphate, an inhibitor of transforming growth factor-beta, improves range of motion after flexor tendon repair. J Bone Joint Surg Am, 2006. 88(11): p. 2465-72.