The expression and regulation of microRNA-125b in cancers

Acta Biochimica et Biophysica Sinica

Volumn 45, Issue 10, 2013, Pages 803-805

  Huang, Ke ^a   Dong, Shiwu ^a   Li, Wei ^a   Xie, Zhao ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Cancer; Gene expression; MiR 125b; Target gene

Indexed keywords

MICRORNA; MIRN125 MICRORNA, HUMAN;

ANIMAL; APOPTOSIS; CELL PROLIFERATION; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENE TARGETING; GENETICS; HUMAN; MIR-125B; NEOPLASM; PHYSIOLOGY; REVIEW; TARGET GENE; TUMOR CELL LINE;

CANCER; GENE EXPRESSION; MIR-125B; TARGET GENE;

ANIMALS; APOPTOSIS; CELL LINE, TUMOR; CELL PROLIFERATION; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE TARGETING; HUMANS; MICRORNAS; NEOPLASMS;

EID: 84888618295     PISSN: 16729145     EISSN: 17457270     Source Type: Journal    
DOI: 10.1093/abbs/gmt073     Document Type: Review

References (30)

1. Le MT, Xie H, Zhou B, Chia PH, Rizk P, Um M and Udolph G, et al. MicroRNA-125b promotes neuronal differentiation in human cells by repressing multiple targets. Mol Cell Biol 2009, 29: 5290-5305.
2. Le MT, Teh C, Shyh-Chang N, Xie H, Zhou B, Korzh V and Lodish HF, et al. MicroRNA-125b is a novel negative regulator of p53. Genes Dev 2009, 23: 862-876.
3. Lee YS, Kim HK, Chung SM, Kim KS and Dutta A. Depletion of human micro-RNA miR-125b reveals that it is critical for the proliferation of differentiated cells but not for the downregulation of putative targets during differentiation. J Biol Chem 2005, 280: 16635-16641.
4. Lin KY, Zhang XJ, Feng DD, Zhang H, Zeng CW, Han BW and Zhou AD, et al. MiR-125b, a target of CDX2, regulates cell differentiation through repression of the core bnding factor in hematopoietic malignancies. J Biol Chem 2011, 286: 38253-38263.
5. Liu LH, Li H, Li JP, Zhong H, Zhang HC, Chen J and Xiao T. MiR-125b suppresses the proliferation and migration of osteosarcoma cells through down-regulation of STAT3. Biochem Biophys Res Commun 2011, 416: 31-38.
6. Cui EH, Li HJ, Hua F, Wang B, Mao W, Feng XR and Li JY, et al. Serum microRNA-125b as a diagnostic or prognostic biomarker for advanced NSCLC patients receiving cisplatin-based chemotherapy. Acta Pharmacol Sin 2013, 34: 309-313.
7. Negrini M, Rasio D, Hampton GM, Sabbioni S, Rattan S, Carter SL and Rosenberg AL, et al. Definition and refinement of chromosome 11 regions of loss of heterozygosity in breast cancer: identification of a new region at 11q23.3. Cancer Res 1995, 55: 3003-3007.
8. Rasio D, Negrini M, Manenti G, Dragani TA and Croce CM. Loss of heterozygosity at chromosome 11q in lung adenocarcinoma: identification of three independent regions. Cancer Res 1995, 55: 3988-3991.
9. Iorio MV, Ferracin M, Liu CG, Veronese A, Spizzo R, Sabbioni S and Magri E, et al. MicroRNA gene expression deregulation in human breast cancer. Cancer Res 2005, 65: 7065-7070.
10. Vriens MR, Weng J, Suh I, Huynh N, Guerrero MA, Shen WT and Duh QY, et al. MicroRNA expression profiling is a potential diagnostic tool for thyroid cancer. Cancer 2012, 118: 3426-3432.
11. Pallante P, Visone R, Ferracin M, Ferraro A, Berlingieri MT, Troncone G and Chiappetta G, et al. MicroRNA deregulation in human thyroid papillary carcinomas. Endocr Relat Cancer 2006, 13: 497-508.
12. Jia HY, Wang YX, Yan WT, Li HY, Tian YZ, Wang SM and Zhao HL. MicroRNA-125b functions as a tumor suppressor in hepatocellular carcinoma cells. Int J Mol Sci 2012, 13: 8762-8774.
13. Henson BJ, Bhattacharjee S, O'Dee DM, Feingold E and Gollin SM. Decreased expression of miR-125b and miR-100 in oral cancer cells contributes to malignancy. Genes Chromosomes Cancer 2009, 48: 569-582.
14. Hutvagner G, McLachlan J, Pasquinelli AE, Balint E, Tuschl T and Zamore PD. A cellular function for the RNA-interference enzyme dicer in the maturation of the let-7 small temporal RNA. Science 2001, 293: 834-838.
15. Shaham L, Binder V, Gefen N, Borkhardt A and Izraeli S. MiR-125b in normal and malignant hematopoiesis. Leukemia 2012, 26: 2011-2018.
16. Pogue AI, Cui JG, Li YY, Zhao Y, Culicchia F and Lukiw WJ. Micro RNA-125b (miRNA-125b) function in astrogliosis and glial cell proliferation. Neurosci Lett 2010, 476: 18-22.
17. Tili E, Michaille JJ and Croce CM. MicroRNAs play a central role in molecular dysfunctions linking inflammation with cancer. Immunol Rev 2013, 253: 167-184.
18. Lukiw WJ. NF-kB-regulated, proinflammatory miRNAs in Alzheimer's disease. Alzheimers Res Ther 2012, 4: 47-53.
19. Rieske P, Azizi SA, Augelli B, Gaughan J and Krynska B. A population of human brain parenchymal cells express markers of glial, neuronal and early neural cells and differentiate into cells of neuronal and glial lineages. Eur J Neurosci 2007, 25: 31-37.
20. Brahmachari S, Fung YK and Pahan K. Induction of glial fibrillary acidic protein expression in astrocytes by nitric oxide. J Neurosci 2006, 26: 4930-4939.
21. Eng LF and Ghirnikar RS. GFAP and astrogliosis. Brain Pathology 1994, 4: 229-237.
22. Lukiw WJ and Pogue AI. Induction of specific micro RNA (miRNA) species by ROS-generating metal sulfates in primary human brain cells. J Inorg Biochem 2007, 101: 1265-1269.
23. Sethi P and Lukiw WJ. Micro-RNA abundance and stability in human brain: Specific alterations in Alzheimer's disease temporal lobe neocortex. Neurosci Lett 2009, 459: 100-104.
24. Lukiw WJ. Micro-RNA speciation in fetal, adult and Alzheimer's disease hippocampus. Neuroreport 2007, 18: 297-300.
25. Foulkes WD. p53-master and commander. N Engl J Med 2007, 357: 2539-2541.
26. Cui Y, Xiao ZF, Han J, Sun J, Ding WY, Zhao YN and Chen B, et al. MiR- 125b orchestrates cell proliferation, differentiation and migration in neural stem/progenitor cells by targeting Nestin. BMC Neuroscience 2012, 13: 116.
27. Nishida N, Yokobori T, Mimori K, Sudo T, Tanaka F, Shibata K and Ishii H, et al. MicroRNA miR-125b is a prognostic marker in human colorectal cancer. Int J Oncol 2011, 38: 1437-1443.
28. Guan Y, Yao HL, Zheng ZH, Qiu GR and Sun KL. MiR-125b targets BCL3 and suppresses ovarian cancer proliferation. Int J Cancer 2011, 128: 2274-2283.
29. Huang L, Luo JH, Cai QQ, Pan QH, Zeng H, Guo ZH and Dong W, et al. MicroRNA-125b suppresses the development of bladder cancer by targeting E2F3. Int J Cancer 2011, 128: 1758-1769.
30. Shi XB, Xue L, Yang J, Ma AH, Zhao J, Xu M and Tepper CG, et al. An androgen-regulated miRNA suppresses Bak1 expression and induces androgen-independent growth of prostate cancer cells. Proc Natl Acad Sci USA 2007, 104: 19983-19988.