Targeted precise quantification of 12 human recombinant uridine-diphosphate glucuronosyl transferase 1A and 2B isoforms using nano-ultra-high-performance liquid chromatography/tandem mass spectrometry with selected reaction monitoring

Drug Metabolism and Disposition

Volumn 41, Issue 12, 2013, Pages 2076-2080

  Fallon, John K ^a   Neubert, Hendrik ^b   Goosen, Theunis C ^c   Smith, Philip C ^a  

^a University of North Carolina   (United States)

^b PFIZER INC   (United States)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

GLUCURONOSYLTRANSFERASE; GLUCURONOSYLTRANSFERASE 1A1; GLUCURONOSYLTRANSFERASE 1A10; GLUCURONOSYLTRANSFERASE 1A3; GLUCURONOSYLTRANSFERASE 1A4; GLUCURONOSYLTRANSFERASE 1A6; GLUCURONOSYLTRANSFERASE 1A7; GLUCURONOSYLTRANSFERASE 1A8; GLUCURONOSYLTRANSFERASE 1A9; GLUCURONOSYLTRANSFERASE 2B15; GLUCURONOSYLTRANSFERASE 2B17; GLUCURONOSYLTRANSFERASE 2B4; GLUCURONOSYLTRANSFERASE 2B7; UNCLASSIFIED DRUG; URIDINE DIPHOSPHATE GLUCORONOSYLTRANSFERASE 1A; URIDINE DIPHOSPHATE GLUCORONOSYLTRANSFERASE 2B;

ARTICLE; CATALYSIS; CONTROLLED STUDY; DRUG ABSORPTION; DRUG DISTRIBUTION; DRUG EXCRETION; DRUG METABOLISM; HUMAN; HUMAN CELL; KIDNEY MICROSOME; LIMIT OF DETECTION; LIMIT OF QUANTITATION; LIVER MICROSOME; PRIORITY JOURNAL; REACTION ANALYSIS; TANDEM MASS SPECTROMETRY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY;

CATALYSIS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; GLUCURONOSYLTRANSFERASE; HUMANS; PROTEIN ISOFORMS; RECOMBINANT PROTEINS; TANDEM MASS SPECTROMETRY;

EID: 84888601124     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.113.053801     Document Type: Article

References (13)

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