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Volumn 18, Issue 11, 2013, Pages 13920-13939

A combination of alkaloids and triterpenes of alstonia scholaris (Linn.) R. Br. leaves enhances immunomodulatory activity in C57BL/6 mice and induces apoptosis in the a549 cell line

Author keywords

Alstonia scholaris (Linn.) R. Br.; Antitumor; Apoptosis; Immunomodulatory; Non small cell lung cancer

Indexed keywords

ALKALOID; IMMUNOLOGIC FACTOR; INTERLEUKIN 6; TRITERPENE; TUMOR NECROSIS FACTOR ALPHA;

EID: 84888595305     PISSN: None     EISSN: 14203049     Source Type: Journal    
DOI: 10.3390/molecules181113920     Document Type: Article
Times cited : (19)

References (34)
  • 2
    • 70349855202 scopus 로고    scopus 로고
    • Comparison of antitumor activities of different polysaccharide fractions from the stems of Dendrobium nobile Lindl
    • Wang, J.H.; Luo, J.P.; Zha, X.Q.; Feng, B.J. Comparison of antitumor activities of different polysaccharide fractions from the stems of Dendrobium nobile Lindl. Carbohydr. Polym. 2010, 79, 114-118.
    • (2010) Carbohydr. Polym. , vol.79 , pp. 114-118
    • Wang, J.H.1    Luo, J.P.2    Zha, X.Q.3    Feng, B.J.4
  • 3
    • 84874572641 scopus 로고    scopus 로고
    • The efficacy of Chinese herbal medicine as an adjunctive therapy for advanced non-small cell lung cancer: A systematic review and meta-analysis
    • Li, S.G.; Chen, H.Y.; Ou-Yang, C.S.; Wang, X.X.; Yang, Z.J.; Tong, Y.; Cho, W.C. The efficacy of Chinese herbal medicine as an adjunctive therapy for advanced non-small cell lung cancer: A systematic review and meta-analysis. PLoS One 2013, 8, e57604.
    • (2013) PLoS One , vol.8
    • Li, S.G.1    Chen, H.Y.2    Ou-Yang, C.S.3    Wang, X.X.4    Yang, Z.J.5    Tong, Y.6    Cho, W.C.7
  • 4
    • 34250381155 scopus 로고    scopus 로고
    • Differential control of growth, cell cycle progression, and gene expression in human estrogen receptor positive MCF-7 breast cancer cells by extracts derived from polysaccharopeptide I'm-Yunity and Danshen and their combination
    • Hsieh, T.C.; Wu, J.M. Differential control of growth, cell cycle progression, and gene expression in human estrogen receptor positive MCF-7 breast cancer cells by extracts derived from polysaccharopeptide I'm-Yunity and Danshen and their combination. Int. J. Oncol. 2006, 29, 1215-1222.
    • (2006) Int. J. Oncol. , vol.29 , pp. 1215-1222
    • Hsieh, T.C.1    Wu, J.M.2
  • 6
    • 13244249861 scopus 로고    scopus 로고
    • Interface strategies in modular product innovation
    • Chen, K.M.; Liu, R.J. Interface strategies in modular product innovation. Technovation 2005, 25, 771-782.
    • (2005) Technovation , vol.25 , pp. 771-782
    • Chen, K.M.1    Liu, R.J.2
  • 7
    • 79952563867 scopus 로고    scopus 로고
    • Integrative medicine-Traditional Chinese medicine, a model? Chin
    • Robinson, N. Integrative medicine-Traditional Chinese medicine, a model? Chin. J. Integr. Med. 2011, 17, 21-25.
    • (2011) J. Integr. Med. , vol.17 , pp. 21-25
    • Robinson, N.1
  • 9
    • 14644426511 scopus 로고    scopus 로고
    • Evaluation of Alstonia scholaris leaves for broncho-vasodilatory activity
    • Channa, S.; Dar, A.; Ahmed, S.; Atta-ur-Rahman. Evaluation of Alstonia scholaris leaves for broncho-vasodilatory activity. J. Ethnopharmacol. 2005, 97, 469-476.
    • (2005) J. Ethnopharmacol. , vol.97 , pp. 469-476
    • Channa, S.1    Dar, A.2    Ahmed, S.3    Atta-Ur-Rahman4
  • 10
    • 53649108143 scopus 로고    scopus 로고
    • Study of the anti-proliferative effects and synergy of phthalides from Angelica sinensis on colon cancer cells
    • Kan, W.L.; Cho, C.H.; Rudd, J.A.; Lin, G. Study of the anti-proliferative effects and synergy of phthalides from Angelica sinensis on colon cancer cells. J. Ethnopharmacol. 2008, 120, 36-43.
    • (2008) J. Ethnopharmacol. , vol.120 , pp. 36-43
    • Kan, W.L.1    Cho, C.H.2    Rudd, J.A.3    Lin, G.4
  • 13
    • 0030899063 scopus 로고    scopus 로고
    • Activity of extracts and alkaloids of Thai Alstonia species against human lung cancer cell lines
    • Keawpradub, N.; Houghton, P.J.; Eno-Amooquaye, E.; Burke, P.J. Activity of extracts and alkaloids of Thai Alstonia species against human lung cancer cell lines. Planta Med. 1997, 63, 97-101.
    • (1997) Planta Med. , vol.63 , pp. 97-101
    • Keawpradub, N.1    Houghton, P.J.2    Eno-Amooquaye, E.3    Burke, P.J.4
  • 14
    • 84924407873 scopus 로고    scopus 로고
    • Review of the phytochemical, pharmacological and toxicological properties of Alstonia Scholaris Linn
    • R. Br (Saptaparna) [Epub ahead of print]
    • Baliga, M.S. Review of the phytochemical, pharmacological and toxicological properties of Alstonia Scholaris Linn. R. Br (Saptaparna). Chin. J. Integr. Med. 2012, [Epub ahead of print].
    • (2012) Chin. J. Integr. Med.
    • Baliga . M, S.1
  • 15
    • 0033697116 scopus 로고    scopus 로고
    • Plants used against cancer-An extension of the work of Jonathan Hartwell
    • Graham, J.G.; Quinn, M.L.; Fabricant, D.S.; Farnsworth, N.R. Plants used against cancer-An extension of the work of Jonathan Hartwell. J. Ethnopharmacol. 2000, 73, 347-377.
    • (2000) J. Ethnopharmacol. , vol.73 , pp. 347-377
    • Graham, J.G.1    Quinn, M.L.2    Fabricant, D.S.3    Farnsworth, N.R.4
  • 16
    • 64949186513 scopus 로고    scopus 로고
    • Alstonic acids A and B, unusual 2,3-secofernane triterpenoids from Alstonia scholaris
    • Wang, F.; Ren, F.C.; Liu, J.K. Alstonic acids A and B, unusual 2,3-secofernane triterpenoids from Alstonia scholaris. Phytochemistry 2009, 70, 650-654.
    • (2009) Phytochemistry , vol.70 , pp. 650-654
    • Wang, F.1    Ren, F.C.2    Liu, J.K.3
  • 17
    • 70449394399 scopus 로고    scopus 로고
    • A traditional Chinese medicine formulation consisting of Rhizoma Corydalis and Rhizoma Curcumae exerts synergistic anti-tumor activity
    • Gao, J.L.; He, T.C.; Li, Y.B.; Wang, Y.T. A traditional Chinese medicine formulation consisting of Rhizoma Corydalis and Rhizoma Curcumae exerts synergistic anti-tumor activity. Oncol. Rep. 2009, 22, 1077-1083.
    • (2009) Oncol. Rep. , vol.22 , pp. 1077-1083
    • Gao, J.L.1    He, T.C.2    Li, Y.B.3    Wang, Y.T.4
  • 19
    • 9644304559 scopus 로고    scopus 로고
    • The effect of seasonal variation on the antineoplastic activity of Alstonia scholaris R
    • Jagetia, G.C.; Baliga, M.S. The effect of seasonal variation on the antineoplastic activity of Alstonia scholaris R. Br. in HeLa cells. J. Ethnopharmacol. 2005, 96, 37-42.
    • (2005) Br. in HeLa Cells. J. Ethnopharmacol. , vol.96 , pp. 37-42
    • Jagetia, G.C.1    Baliga, M.S.2
  • 20
    • 33144466297 scopus 로고    scopus 로고
    • Evaluation of anticancer activity of the alkaloid fraction of Alstonia scholaris (Sapthaparna) in vitro and in vivo
    • Jagetia, G.C.; Baliga, M.S. Evaluation of anticancer activity of the alkaloid fraction of Alstonia scholaris (Sapthaparna) in vitro and in vivo. Phytother. Res. 2006, 20, 103-109.
    • (2006) Phytother. Res. , vol.20 , pp. 103-109
    • Jagetia, G.C.1    Baliga, M.S.2
  • 21
    • 84875936184 scopus 로고    scopus 로고
    • Harnessing the immune system for the treatment of non-small-cell lung cancer
    • Brahmer, J.R. Harnessing the immune system for the treatment of non-small-cell lung cancer. J. Clin. Oncol. 2013, 31, 1021-1028.
    • (2013) J. Clin. Oncol. , vol.31 , pp. 1021-1028
    • Brahmer . J, R.1
  • 25
    • 84862828285 scopus 로고    scopus 로고
    • Antitumor effects and chemical compositions of Eupolyphaga sinensis Walker ethanol extract
    • Ge, G.F.; Yu, C.H.; Yu, B.; Shen, Z.H.; Zhang, D.L.; Wu, Q.F. Antitumor effects and chemical compositions of Eupolyphaga sinensis Walker ethanol extract. J. Ethnopharmacol. 2012, 141, 178-182.
    • (2012) J. Ethnopharmacol. , vol.141 , pp. 178-182
    • Ge, G.F.1    Yu, C.H.2    Yu, B.3    Shen, Z.H.4    Zhang, D.L.5    Wu, Q.F.6
  • 26
    • 84861332498 scopus 로고    scopus 로고
    • Anticancer potential of aqueous extract of alocasia macrorrhiza against hepatic cancer in vitro and in vivo
    • Fang, S.; Lin, C.; Zhang, Q.; Wang, L.; Lin, P.; Zhang, J.; Wang, X. Anticancer potential of aqueous extract of alocasia macrorrhiza against hepatic cancer in vitro and in vivo. J. Ethnopharmacol. 2012, 141, 947-956.
    • (2012) J. Ethnopharmacol. , vol.141 , pp. 947-956
    • Fang, S.1    Lin, C.2    Zhang, Q.3    Wang, L.4    Lin, P.5    Zhang, J.6    Wang, X.7
  • 27
    • 84864367909 scopus 로고    scopus 로고
    • Global cancer transitions according to the Human Development Index (2008-2030): A population-based study
    • Bray, F.; Jemal, A.; Grey, N.; Ferlay, J.; Forman, D. Global cancer transitions according to the Human Development Index (2008-2030): A population-based study. Lancet. Oncol. 2012, 13, 790-801.
    • (2012) Lancet. Oncol. , vol.13 , pp. 790-801
    • Bray, F.1    Jemal, A.2    Grey, N.3    Ferlay, J.4    Forman, D.5
  • 28
    • 67650675111 scopus 로고    scopus 로고
    • Impact of natural products on developing new anti-cancer agents
    • Cragg, G.M.; Grothaus, P.G.; Newman, D.J. Impact of natural products on developing new anti-cancer agents. Chem. Rev. 2009, 109, 3012-3043.
    • (2009) Chem. Rev. , vol.109 , pp. 3012-3043
    • Cragg, G.M.1    Grothaus, P.G.2    Newman, D.J.3
  • 31
    • 61849148824 scopus 로고    scopus 로고
    • Natural products and drug discovery. Can thousands of years of ancient medical knowledge lead us to new and powerful drug combinations in the fight against cancer and dementia?
    • Ji, H.F.; Li, X.J.; Zhang, H.Y. Natural products and drug discovery. Can thousands of years of ancient medical knowledge lead us to new and powerful drug combinations in the fight against cancer and dementia? EMBO Rep. 2009, 10, 194-200.
    • (2009) EMBO Rep. , vol.10 , pp. 194-200
    • Ji, H.F.1    Li, X.J.2    Zhang, H.Y.3
  • 32
    • 34247327829 scopus 로고    scopus 로고
    • Antitumor activity of the methanol extract of Hypericum hookerianum stem against Ehrlich ascites carcinoma in Swiss albino mice
    • Dongre, S.H.; Badami, S.; Natesan, S.; H, R.C. Antitumor activity of the methanol extract of Hypericum hookerianum stem against Ehrlich ascites carcinoma in Swiss albino mice. J. Pharmacol. Sci. 2007, 103, 354-359.
    • (2007) J. Pharmacol. Sci. , vol.103 , pp. 354-359
    • Dongre, S.H.1    Badami, S.2    Natesan, S.3
  • 33
    • 78650553809 scopus 로고    scopus 로고
    • Coleusin factor exerts cytotoxic activity by inducing G0/G1 cell cycle arrest and apoptosis in human gastric cancer BGC-823 cells
    • Sun, B.; Geng, S.; Huang, X.; Zhu, J.; Liu, S.; Zhang, Y.; Ye, J.; Wang, J. Coleusin factor exerts cytotoxic activity by inducing G0/G1 cell cycle arrest and apoptosis in human gastric cancer BGC-823 cells. Cancer Lett. 2011, 301, 95-105.
    • (2011) Cancer Lett. , vol.301 , pp. 95-105
    • Sun, B.1    Geng, S.2    Huang, X.3    Zhu, J.4    Liu, S.5    Zhang, Y.6    Ye, J.7    Wang, J.8
  • 34
    • 78650664040 scopus 로고    scopus 로고
    • Antioxidant activities of total phenols of Prunella vulgaris L. in vitro and in tumor-bearing mice
    • Feng, L.; Jia, X.; Zhu, M.M.; Chen, Y.; Shi, F. Antioxidant activities of total phenols of Prunella vulgaris L. in vitro and in tumor-bearing mice. Molecules 2010, 15, 9145-9156.
    • (2010) Molecules , vol.15 , pp. 9145-9156
    • Feng, L.1    Jia, X.2    Zhu, M.M.3    Chen, Y.4    Shi, F.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.