Development of a high-throughput replicon assay for the identification of respiratory syncytial virus inhibitors

Antiviral Research

Volumn 101, Issue 1, 2014, Pages 75-81

  Tiong Yip, Choi Lai ^a   Plant, Helen ^a   Sharpe, Paul ^a   Fan, Jun ^a   Rich, Kirsty ^a   Gorseth, Elise ^a   Yu, Qin ^a  

^a ASTRAZENECA   (United Kingdom)

Author keywords

Antiviral; HTS; Luminescence; Multiplex; Replicon; RSV

Indexed keywords

ANTIVIRUS AGENT; BI CPD D; DIMETHYL SULFOXIDE; OSELTAMIVIR; RENILLA LUCIFERIN 2 MONOOXYGENASE; RESPIRATORY SYNCYTIAL VIRUS INHIBITOR; RIBAVIRIN; UNCLASSIFIED DRUG; YM 53403; YM53403; MULTIPLEX;

ANIMAL CELL; ARTICLE; CELL CULTURE; CELL DENSITY; CELL LINE; CELL PROLIFERATION; CRYOPRESERVATION; CYTOTOXICITY; DEVELOPMENT; DRUG IDENTIFICATION; DRUG SENSITIVITY; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; HIGH THROUGHPUT SCREENING; INCUBATION TIME; NONHUMAN; PRIORITY JOURNAL; REPLICON; REPLICON ASSAY; REPRODUCIBILITY; RESPIRATORY SYNCYTIAL PNEUMOVIRUS; VALIDATION PROCESS; VIRUS INFECTIVITY; VIRUS INHIBITION; VIRUS REPLICATION; VIRUS TITRATION; CONTROLLED STUDY; CYTOTOXICITY ASSAY; PROCESS OPTIMIZATION; VIRUS IDENTIFICATION; CELL SURVIVAL; DRUG EFFECT; DRUG SCREENING; GENETICS; HAZARDOUS WASTE; HTS; HUMAN; ISOLATION AND PURIFICATION; LUMINESCENCE; METHODOLOGY; PHYSIOLOGY; RSV; VALIDATION STUDY;

RESPIRATORY SYNCYTIAL VIRUS; RICE STRIPE VIRUS;

ANTIVIRAL; HTS; LUMINESCENCE; MULTIPLEX; REPLICON; RSV;

ANTIVIRAL AGENTS; CELL SURVIVAL; CONTAINMENT OF BIOHAZARDS; DRUG EVALUATION, PRECLINICAL; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; REPLICON; REPRODUCIBILITY OF RESULTS; RESPIRATORY SYNCYTIAL VIRUSES; VIRUS REPLICATION;

EID: 84888586820     PISSN: 01663542     EISSN: 18729096     Source Type: Journal    
DOI: 10.1016/j.antiviral.2013.11.003     Document Type: Article

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