FGF-1 delivery from multilayer alginate microbeads stimulates a rapid and persistent increase in vascular density

Microvascular Research

Volumn 90, Issue , 2013, Pages 23-29

  Khanna, Omaditya ^a   Huang, Jung Ju ^b   Moya, Monica L ^c   Wu, Chih Wei ^b   Cheng, Ming Huei ^b   Opara, Emmanuel C ^d   Brey, Eric M ^a,e  

^a Illinois Institute of Technology   (United States)

^b CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

^c University of California at Irvine   (United States)

^d WAKE FOREST SCHOOL OF MEDICINE   (United States)

^e HINES VA HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALGINIC ACID; ALPHA SMOOTH MUSCLE ACTIN; CD31 ANTIGEN; FIBROBLAST GROWTH FACTOR 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL REACTIVITY; CAPILLARY DENSITY; CELL DENSITY; DRUG DELIVERY SYSTEM; DRUG RELEASE; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; MICROENCAPSULATION; NONHUMAN; OMENTUM; PERICYTE; PRIORITY JOURNAL; RAT; VASCULARIZATION;

RATTUS;

ACTINS; ALGINATES; ANGIOGENESIS INDUCING AGENTS; ANIMALS; ANTIGENS, CD31; BIOLOGICAL MARKERS; DELAYED-ACTION PREPARATIONS; DRUG CARRIERS; ENDOTHELIAL CELLS; FIBROBLAST GROWTH FACTOR 1; GLUCURONIC ACID; HEXURONIC ACIDS; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; NEOVASCULARIZATION, PHYSIOLOGIC; OMENTUM; RATS; RATS, SPRAGUE-DAWLEY; TIME FACTORS;

EID: 84888440152     PISSN: 00262862     EISSN: 10959319     Source Type: Journal    
DOI: 10.1016/j.mvr.2013.08.006     Document Type: Article

References (28)

1. Alejandro R., Lehmann R., Ricordi C., Kenyon N.S., Angelico M.C., Burke G., et al. Long-term function (6years) of islet allografts in type 1 diabetes. Diabetes 1997, 46:1983-1989.
2. Basta G., Sarchielli P., Luca G., Racanicchi L., Nastruzzi C., Guido L., et al. Optimized parameters for microencapsulation of pancreatic islet cells: an in vitro study clueing on islet graft immunoprotection in type 1 diabetes mellitus. Transpl. Immunol. 2004, 13:289-296.
3. Basta G., Montanucci P., Luca G., Boselli C., Noya G., Barbaro B., et al. Long-term metabolic and immunological follow-up of nonimmunosuppressed patients with type 1 diabetes treated with microencapsulated islet allografts: four cases. Diabetes Care 2011, 34:2406-2409.
4. Brey E.M., Uriel S., Greisler H.P., McIntire L.V. Therapeutic neovascularization: contributions from bioengineering. Tissue Eng. 2005, 11:567-584.
5. Darland D.C., D'Amore P.A. Blood vessel maturation: vascular development comes of age. J. Clin. Invest. 1999, 103:157-158.
6. Elliot R.B., Garkavenko O., Tan P., Skaletsky N.N., Guilev A., Draznin B., et al. Transplantation of microencapsulated neonatal porcine islets in patients with type 1 diabetes: safety and efficacy. Diabetes 2010, 59:A44.
7. Elliott R.B., Escobar L., Tan P.L., Muzina M., Zwain S., Buchanan C. Live encapsulated porcine islets from a type 1 diabetic patient 9.5yr after xenotransplantation. Xenotransplantation 2007, 14:157-161.
8. Garfinkel M.R., Harland R.C., Opara E.C. Optimization of the microencapsulated islet for transplantation. J. Surg. Res. 1998, 76:7-10.
9. Gu F., Amsden B., Neufield R. Sustained delivery of vascular endothelial growth factor with alginate beads. J. Control. Release 2004, 96:463-472.
10. Jay S.M., Saltzman W.M. Controlled delivery of VEGF via modulation of alginate microparticle ionic crosslinking. J. Control. Release 2009, 134:26-34.
11. Jen A.C., Wake M.C., Mikos A.G. Review: hydrogels for cell immobilization. Biotechnol. Bioeng. 1996, 50:357-364.
12. Khanna O., Moya M.L., Opara E.C., Brey E.M. Synthesis of multilayered alginate microcapsules for the sustained release of fibroblast growth factor-1. J. Biomed. Mater. Res. A 2010, 95:632-640.
13. Khanna O., Moya M.L., Greisler H.P., Opara E.C., Brey E.M. Multilayered microcapsules for the sustained-release of angiogenic proteins from encapsulated cells. Am. J. Surg. 2010, 200:655-658.
14. Kizilel S., Garfinkel M., Opara E. The bioartificial pancreas: progress and challenges. Diabetes Technol. Ther. 2005, 7:968-985.
15. Lim G.J., Zare S., Van Dyke M., Atala A. Cell microencapsulation. Adv. Exp. Med. Biol. 2010, 670:126-136.
16. McQuilling J.P., Arenas-Herrera J., Childers C., Pareta R.A., Khanna O., Jiang B., et al. New alginate microcapsule system for angiogenic protein delivery and immunoisolation of islets for transplantation in the rat omentum pouch. Transplant. Proc. 2011, 43:3262-3264.
17. Moya M.L., Lucas S., Francis-Sedlak M., Liu X., Garfinkel M.R., Huang J.J., et al. Sustained delivery of FGF-1 increases vascular density in comparison to bolus administration. Microvasc. Res. 2009, 78:142-147.
18. Moya M.L., Garfinkel M.R., Liu X., Lucas S., Opara E.C., Greisler H.P., et al. Fibroblast growth factor-1 (FGF-1) loaded microbeads enhances local capillary neovascularization. J. Surg. Res. 2010, 160:208-212.
19. Moya M.L., Cheng M.H., Huang J.J., Francis-Sedlak M.E., Kao S.W., Opara E.C., et al. The effect of FGF-1 loaded alginate microbeads on neovascularization and adipogenesis in a vascular pedicle model of adipose tissue engineering. Biomaterials 2010, 31:2816-2826.
20. Moya M.L., Morley M., Khanna O., Opara E.C., Brey E.M. Stability of alginate microbead properties in vitro. J. Mater. Sci. Mater. Med. 2012, 23:903-912.
21. Nomi M., Atala A., Coppi P.D., Soker S. Principals of neovascularization for tissue engineering. Mol. Aspects Med. 2002, 23:463-483.
22. Opara E.C., Mirmalek-Sani S.H., Khanna O., Moya M.L., Brey E.M. Design of a bioartificial pancreas. J. Investig. Med. 2010, 58:831-837.
23. Prochorov A.V., Tretjak S.I., Goranov V.A., Glinnik A.A., Goltsev M.V. Treatment of insulin dependent diabetes mellitus with intravascular transplantation of pancreatic islet cells without immunosuppressive therapy. Adv. Med. Sci. 2008, 53:240-244.
24. Smith M.K., Peters M.C., Richardson T.P., Garbern J.C., Mooney D.J. Locally enhanced angiogenesis promotes transplanted cell survival. Tissue Eng. 2004, 10:63-71.
25. Tuch B.E., Keogh G.W., Williams L.J., Wu W., Foster J.L., Vaithilingam V., et al. Safety and viability of microencapsulated human islets transplanted into diabetic humans. Diabetes Care 2009, 32:1887-1889.
26. Tuch B.E., Hughes T.C., Evans M.D. Encapsulated pancreatic progenitors derived from human embryonic stem cells as a therapy for insulin-dependent diabetes. Diabetes Metab. Res. Rev. 2011, 27:928-932.
27. Uriel S., Brey E.M., Greisler H.P. Sustained low levels of fibroblast growth factor-1 promote persistent microvascular network formation. Am. J. Surg. 2006, 192:604-609.
28. Vanacker J., Luyckx V., Dolmans M.M., Des Rieux A., Jaeger J., Van Langendonckt A., et al. Transplantation of an alginate-matrigel matrix containing isolated ovarian cells: first step in developing a biodegradable scaffold to transplant isolated preantral follicles and ovarian cells. Biomaterials 2012, 33:6079-6085.