Multilayered microcapsules for the sustained-release of angiogenic proteins from encapsulated cells

American Journal of Surgery

Volumn 200, Issue 5, 2010, Pages 655-658

  Khanna, Omaditya ^a   Moya, Monica L ^a   Greisler, Howard P ^b,c   Opara, Emmanuel C ^a,d   Brey, Eric M ^a,b  

^a Illinois Institute of Technology   (United States)

^b HINES VA HOSPITAL   (United States)

^c LOYOLA UNIVERSITY MEDICAL CENTER   (United States)

^d WAKE FOREST SCHOOL OF MEDICINE   (United States)

Author keywords

Alginate; FGF 1; Heparin binding growth associated molecule; Neovascularization

Indexed keywords

ACIDIC FIBROBLAST GROWTH FACTOR; ALGINIC ACID; ANGIOGENIC PROTEIN; FIBROBLAST GROWTH FACTOR 1; MANNURONIC ACID;

ARTICLE; CELL ENCAPSULATION; CHIMERA; MICROCAPSULE; PRIORITY JOURNAL; SUSTAINED DRUG RELEASE;

ALGINATES; ANGIOGENIC PROTEINS; BIOCOMPATIBLE MATERIALS; CARRIER PROTEINS; CELL MEMBRANE; CYTOKINES; DELAYED-ACTION PREPARATIONS; DRUG CARRIERS; GLUCURONIC ACID; HEXURONIC ACIDS; HUMANS; MICROSPHERES;

EID: 78149298198     PISSN: 00029610     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.amjsurg.2010.08.001     Document Type: Article

References (14)

1. G. Miao, J. Mace, and M. Kirby Beneficial effects of nerve growth factor on islet transplantation Transplant Proc 37 2005 3490 3492
2. S. Kizilel, M. Garfinkel, and E. Opara The bioartificial pancreas: progress and challenges Diabetes Technol Ther 7 2005 968 985
3. A.D. Augst, H.J. Kong, and D.J. Mooney Alginate hydrogels as biomaterials Macromol Biosci 6 2006 623 633
4. M.L. Moya, M.R. Garfinkel, and X. Liu Fibroblast growth factor-1 (FGF-1) loaded microbeads enhance local capillary neovascularization J Surg Res 160 2010 208 212
5. M.R. Garfinkel, R.C. Harland, and E.C. Opara Optimization of the microencapsulated islet for transplantation J Surg Res 76 1998 7 10
6. K.E. Dionne, C.K. Colton, and M.L. Yarmush Effect of hypoxia on insulin secretion by isolated rat and canine islets of Langerhans Diabetes 42 1993 12 21
7. A.M. Davalli, L. Scaglia, D.H. Zangen, J. Hollister, S. Bonner-Weir, and G.C. Weir Vulnerability of islets in the immediate posttransplantation period Dynamic changes in structure and function Diabetes 45 1996 1161 1167
8. O. Khanna, M.L. Moya, E.C. Opara, and E.M. Brey Synthesis of multilayered alginate microcapsules for the sustained-release of fibroblast growth factor-1 J Biomed Mat Res 95 2010 632 640
9. L. Xue, A.K. Tassiopoulos, and S.K. Woloson Construction and biological characterization of an HB-GAM/FGF-1 chimera for vascular tissue engineering J Vasc Surg 33 2001 554 560
10. L. Brewster, E.M. Brey, and M. Addis Improving endothelial healing with novel chimeric mitogens Am J Surg 192 2006 589 593
11. C.R. Ozawa, A. Banfi, and N.L. Glazer Microenvironmental VEGF concentration, not total dose, determines a threshold between normal and aberrant angiogenesis J Clin Invest 113 2004 516 527
12. S. Uriel, E.M. Brey, and H.P. Greisler Sustained low levels of fibroblast growth factor-1 promote persistent microvascular network formation Am J Surg 192 2006 604 609
13. M.L. Moya, S. Lucas, and M. Francis-Sedlak Sustained delivery of FGF-1 increases vascular density in comparison to bolus administration Microvasc Res 78 2009 142 147
14. J.A. Rowley, G. Madlambayan, and D.J. Mooney Alginate hydrogels as synthetic extracellular matrix materials Biomaterials 20 1999 45 53