Ovulation-inducing drugs and ovarian cancer risk: Results from an extended follow-up of a large United States infertility cohort

Fertility and Sterility

Volumn 100, Issue 6, 2013, Pages 1660-1666

  Trabert, Britton ^a   Lamb, Emmet J ^b   Scoccia, Bert ^c   Moghissi, Kamran S ^d   Westhoff, Carolyn L ^e   Niwa, Shelley ^f   Brinton, Louise A ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b STANFORD UNIVERSITY   (United States)

^c UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^d WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e Columbia University ^*  (United States)

^f WESTAT   (United States)

Author keywords

clomiphene citrate; gonadotropins; infertility; Ovarian cancer; risk

Indexed keywords

CLOMIFENE CITRATE; GONADOTROPIN; CLOMIFENE; FERTILITY PROMOTING AGENT;

ADULT; AGE; ANOVULATION; ARTICLE; BODY MASS; CANCER RISK; COHORT ANALYSIS; DRUG EXPOSURE; DRUG USE; ENDOMETRIOSIS; FEMALE; FEMALE INFERTILITY; FOLLOW UP; HUMAN; MAJOR CLINICAL STUDY; MENARCHE; NULLIGRAVIDA; OBESITY; OVARY CANCER; OVULATION INDUCTION; PRIORITY JOURNAL; RETROSPECTIVE STUDY; UNITED STATES; CLINICAL TRIAL; COMORBIDITY; DRUG-RELATED SIDE EFFECTS AND ADVERSE REACTIONS; EPIDEMIOLOGY; INCIDENCE; INFERTILITY, FEMALE; MIDDLE AGED; MULTICENTER STUDY; OVARIAN NEOPLASMS; RISK FACTOR; STATISTICS AND NUMERICAL DATA; TREATMENT OUTCOME;

ADULT; CAUSALITY; CLOMIPHENE; COHORT STUDIES; COMORBIDITY; DRUG-RELATED SIDE EFFECTS AND ADVERSE REACTIONS; FEMALE; FERTILITY AGENTS, FEMALE; FOLLOW-UP STUDIES; GONADOTROPINS; HUMANS; INCIDENCE; INFERTILITY, FEMALE; MIDDLE AGED; OVARIAN NEOPLASMS; OVULATION INDUCTION; RETROSPECTIVE STUDIES; RISK FACTORS; TREATMENT OUTCOME; UNITED STATES;

EID: 84888440025     PISSN: 00150282     EISSN: 15565653     Source Type: Journal    
DOI: 10.1016/j.fertnstert.2013.08.008     Document Type: Article

References (21)

1. L.A. Brinton, V.V. Sahasrabuddhe, and B. Scoccia Fertility drugs and the risk of breast and gynecologic cancers Semin Reprod Med 30 2012 131 145
2. A.S. Whittemore, R. Harris, and J. Itnyre Characteristics relating to ovarian cancer risk: collaborative analysis of 12 US case-control studies. II. Invasive epithelial ovarian cancers in white women. Collaborative Ovarian Cancer Group Am J Epidemiol 136 1992 1184 1203
3. M.A. Rossing, J.R. Daling, N.S. Weiss, D.E. Moore, and S.G. Self Ovarian tumors in a cohort of infertile women N Engl J Med 331 1994 771 776
4. B. Modan, E. Ron, L. Lerner-Geva, T. Blumstein, J. Menczer, and J. Rabinovici Cancer incidence in a cohort of infertile women Am J Epidemiol 147 1998 1038 1042
5. P. Doyle, N. Maconochie, V. Beral, A.J. Swerdlow, and S.L. Tan Cancer incidence following treatment for infertility at a clinic in the UK Hum Reprod 17 2002 2209 2213
6. L.A. Brinton, E.J. Lamb, K.S. Moghissi, B. Scoccia, M.D. Althuis, and J.E. Mabie Ovarian cancer risk after the use of ovulation-stimulating drugs Obstet Gynecol 103 2004 1194 1203
7. I. dos Santos Silva, P.A. Wark, V.A. McCormack, D. Mayer, C. Overton, and V. Little Ovulation-stimulation drugs and cancer risks: a long-term follow-up of a British cohort Br J Cancer 100 2009 1824 1831
8. A. Jensen, H. Sharif, K. Frederiksen, and S.K. Kjaer Use of fertility drugs and risk of ovarian cancer: Danish Population Based Cohort Study BMJ 338 2009 b249
9. K. Sanner, P. Conner, K. Bergfeldt, P. Dickman, K. Sundfeldt, and T. Bergh Ovarian epithelial neoplasia after hormonal infertility treatment: long-term follow-up of a historical cohort in Sweden Fertil Steril 91 2009 1152 1158
10. L. Lerner-Geva, J. Rabinovici, L. Olmer, T. Blumstein, S. Mashiach, and B. Lunenfeld Are infertility treatments a potential risk factor for cancer development? Perspective of 30 years of follow-up Gynecol Endocrinol 28 2012 809 814
11. B.J. Mosgaard, O. Lidegaard, S.K. Kjaer, G. Schou, and A.N. Andersen Infertility, fertility drugs, and invasive ovarian cancer: a case-control study Fertil Steril 67 1997 1005 1012
12. R.B. Ness, D.W. Cramer, M.T. Goodman, S.K. Kjaer, K. Mallin, and B.J. Mosgaard Infertility, fertility drugs, and ovarian cancer: a pooled analysis of case-control studies Am J Epidemiol 155 2002 217 224
13. M.L. Kurta, K.B. Moysich, J.L. Weissfeld, A.O. Youk, C.H. Bunker, and R.P. Edwards Use of fertility drugs and risk of ovarian cancer: results from a U.S.-based case-control study Cancer Epidemiol Biomarkers Prev 21 2012 1282 1292
14. A. Shushan, O. Paltiel, J. Iscovich, U. Elchalal, T. Peretz, and J.G. Schenker Human menopausal gonadotropin and the risk of epithelial ovarian cancer Fertil Steril 65 1996 13 18
15. B.J. Mosgaard, O. Lidegaard, S.K. Kjaer, G. Schou, and A.N. Andersen Ovarian stimulation and borderline ovarian tumors: a case-control study Fertil Steril 70 1998 1049 1055
16. L.A. Brinton, C.L. Westhoff, B. Scoccia, E.J. Lamb, B. Trabert, and S. Niwa Fertility drugs and endometrial cancer risk: results from an extended follow-up of a large infertility cohort Hum Reprod 2013 Aug 13 [Epub]
17. L.A. Brinton, E.J. Lamb, K.S. Moghissi, B. Scoccia, M.D. Althuis, and J.E. Mabie Ovarian cancer risk associated with varying causes of infertility Fertil Steril 82 2004 405 414
18. J. Cohen, R. Forman, S. Harlap, E. Johannisson, B. Lunenfeld, and M.J. de IFFS expert group report on the Whittemore study related to the risk of ovarian cancer associated with the use of infertility agents Hum Reprod 8 1993 996 999
19. G. Potashnik, L. Lerner-Geva, L. Genkin, A. Chetrit, E. Lunenfeld, and A. Porath Fertility drugs and the risk of breast and ovarian cancers: results of a long-term follow-up study Fertil Steril 71 1999 853 859
20. R. Calderon-Margalit, Y. Friedlander, R. Yanetz, K. Kleinhaus, M.C. Perrin, and O. Manor Cancer risk after exposure to treatments for ovulation induction Am J Epidemiol 169 2009 365 375
21. H.P. Yang, B. Trabert, M.A. Murphy, M.E. Sherman, J.N. Sampson, and L.A. Brinton Ovarian cancer risk factors by histologic subtypes in the NIH-AARP Diet and Health Study Int J Cancer 131 2012 938 948