Structure revision and cytotoxic activity of marinamide and its methyl ester, novel alkaloids produced by co-cultures of two marine-derived mangrove endophytic fungi

Natural Product Research

Volumn 27, Issue 21, 2013, Pages 1960-1964

  Zhu, Feng ^a,b   Chen, GuangYing ^a   Wu, JingShu ^b   Pan, JiaHui ^c  

^a HAINAN NORMAL UNIVERSITY   (China)

^b FOSHAN UNIVERSITY   (China)

^c Foshan Supervision Testing Center of Quality and Metrology   (China)

Author keywords

cytotoxic activity; marinamide; quinolone; structure revision

Indexed keywords

4 QUINOLONE DERIVATIVE; ALKALOID; ANTINEOPLASTIC AGENT; MARINAMIDE; METHYL IODIDE; METHYL MARINAMIDE; N METHYL QUINOLACTACIDE; PESTICIDE; PYRIDINE DERIVATIVE; QUINOLACTACIDE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CELL STRAIN HEPG2; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG CYTOTOXICITY; ENDOPHYTE; FEMALE; FUNGUS; HELA CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; MANGROVE; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; X RAY CRYSTALLOGRAPHY;

FUNGI;

ALKALOIDS; CELL SURVIVAL; COCULTURE TECHNIQUES; CRYSTALLOGRAPHY, X-RAY; ESTERS; FUNGI; HELA CELLS; HEP G2 CELLS; HUMANS; LACTAMS; MOLECULAR STRUCTURE; QUINOLONES;

EID: 84888439983     PISSN: 14786419     EISSN: 14786427     Source Type: Journal    
DOI: 10.1080/14786419.2013.800980     Document Type: Article

References (11)

1. Abe M, Imai T, Ishii N, Usui M, Okuda T, Oki T. 2005. Quinolactacide, a new quinolone insecticide from Penicillium citrinum Thom F 1539. Biosci Biotechnol Biochem. 69:1202-1205.
2. Abe M, Imai T, Ishii N, Usui M 2006. Synthesis of quinolactacide via an acyl migration reaction and dehydrogenation with manganese dioxide, and its insecticidal activities. Biosci Biotechnol Biochem. 70:303-306.
3. Blunt JW, Copp BR, Keyzers RA, Munro MHG, Prinsep MR. 2012. Marine natural products. Nat Prod Rep. 29:144-222.
4. Li C-Y, Ding W-J, Shao C-L, She Z-G, Lin Y-C 2010. A new diimide derivative from the co-culture broth of two mangrove fungi (strain no. E33 and K38). J Asian Nat Prod Res. 12:809-813.
5. Mosmann T. 1983. Colorimetric assay cellular growth and survival: Application to proliferation and cytotoxicity assays. J Immunol Methods. 65:55-63.
6. Oh DC, Jensen PR, Kauffman CA, Fenical W. 2005. Libertellenones A-D: Induction of cytotoxic diterpenoid biosynthesis by marine microbial competition. Bioorg Med Chem. 13:5267-5273.
7. Oh DC, Kauffman CA, Jensen PR, Fenical W. 2007. Induced production of emericellamides A and B from the marine-derived fungus Emericella sp. in competing co-culture. J Nat Prod. 70:515-520.
8. Pettit RK. 2009. Mixed fermentation for natural product drug discovery. Appl Microbiol Biotechnol. 83:19-25.
9. Zang LY, Wei W, Guo Y, Wang T, Jiao RH, Ng SW, Tan RX, Ge HM. 2012. Sesquiterpenoids from the mangrove-derived endophytic fungus Diaporthe sp. J Nat Prod. 75:1744-1749.
10. Zhu F, Chen GY, Chen X, Huang MZ, Wan XQ. 2011. Aspergicin, a new antibacterial alkaloid produced by mixed fermentation of two marine-derived mangrove epiphytic fungi. Chem Nat Compd. 47:767-769.
11. Zhu F, Lin YC. 2006. Marinamide, a novel alkaloid and its methyl ester produced by the application of mixed fermentation technique to two mangrove endophytic fungi from the South China Sea. Chin Sci Bull. 51:1426-1430.