A renal metanephric adenoma showing both a 2p16-24 deletion and BRAF V600E mutation: A synergistic role for a tumor suppressor gene on chromosome 2p and BRAF activation?

Cancer Genetics

Volumn 206, Issue 9-10, 2013, Pages 347-352

  Dadone, Bérengère ^a   Ambrosetti, Damien ^a,b   Carpentier, Xavier ^b   Duranton Tanneur, Valérie ^b   Burel Vandenbos, Fanny ^b   Amiel, Jean ^b   Pedeutour, Florence ^a,b  

^a UNIVERSITY OF NICE SOPHIA ANTIPOLIS   (France)

^b UNIVERSITY HOSPITAL OF NICE   (France)

Author keywords

BRAF V600E mutation; Chromosomal imbalance; Metanephric adenoma; Short arm of chromosome 2; Tumor suppressor gene

Indexed keywords

ANAPLASTIC LYMPHOMA KINASE; B RAF KINASE; PROTEIN MSH2; PROTEIN MSH6; VIMENTIN; WT1 PROTEIN;

ABDOMINAL PAIN; ADULT; ALK GENE; ARTICLE; BRAF GENE; CASE REPORT; CHROMOSOME 2P; COMPARATIVE GENOMIC HYBRIDIZATION; COMPUTER ASSISTED TOMOGRAPHY; EXON; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; GENE DELETION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INTERSTITIAL CHROMOSOME DELETION; KIDNEY ADENOMA; METANEPHRIC ADENOMA; MICROSATELLITE INSTABILITY; MSH2 GENE; MSH6 GENE; POINT MUTATION; PRIORITY JOURNAL; TUMOR SUPPRESSOR GENE;

ADENOMA; AMINO ACID SUBSTITUTION; CARRIER PROTEINS; CHROMOSOME DELETION; CHROMOSOMES, HUMAN, PAIR 2; COMPARATIVE GENOMIC HYBRIDIZATION; DNA MUTATIONAL ANALYSIS; ENZYME ACTIVATION; FEMALE; GENES, TUMOR SUPPRESSOR; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; KIDNEY NEOPLASMS; MICROSATELLITE INSTABILITY; MIDDLE AGED; MUTATION; PROTO-ONCOGENE PROTEINS B-RAF;

EID: 84888439424     PISSN: 22107762     EISSN: 22107770     Source Type: Journal    
DOI: 10.1016/j.cancergen.2013.09.002     Document Type: Article

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