Differences between rat strains in the development of PRL-secreting pituitary tumors with long-term estrogen treatment: In vitro insulin-like growth factor-1-induced lactotroph proliferation and gene expression are affected in Wistar-Kyoto rats with low estrogen-susceptibility

Endocrine Journal

Volumn 60, Issue 11, 2013, Pages 1251-1259

  Mitsui, Tetsuo ^a   Ishida, Maho ^a   Izawa, Michi ^a   Arita, Jun ^a  

^a UNIVERSITY OF YAMANASHI   (Japan)

Author keywords

Estrogen; Insulin like growth factor 1; Lactotroph; Proliferation; Strain difference

Indexed keywords

ESTRADIOL; SOMATOMEDIN C; WNT4 PROTEIN;

ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; FEMALE; GENE; GENE EXPRESSION; IN VITRO STUDY; IN VIVO STUDY; MYB11 GENE; NONHUMAN; ONCOGENE MYC; PATHOPHYSIOLOGY; PROLACTIN SECRETING CELL; PROLACTINOMA; RAT; STC1 GENE; STRAIN DIFFERENCE; WISTAR KYOTO RAT; WISTAR RAT; WNT4 GENE;

ANIMALS; CELL PROLIFERATION; CELLS, CULTURED; DOWN-REGULATION; DRUG ADMINISTRATION SCHEDULE; ESTRADIOL; FEMALE; GENE EXPRESSION; INSULIN-LIKE GROWTH FACTOR I; LACTOTROPHS; ORGAN SIZE; PITUITARY GLAND; PITUITARY NEOPLASMS; RATS; RATS, INBRED WKY; RNA, MESSENGER; SPECIES SPECIFICITY; UP-REGULATION;

EID: 84888423332     PISSN: 09188959     EISSN: 13484540     Source Type: Journal    
DOI: 10.1507/endocrj.EJ13-0245     Document Type: Article

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