Increased expression of YKL-40 in mild and moderate/severe persistent allergic rhinitis and its possible contribution to remodeling of nasal mucosa

American Journal of Rhinology and Allergy

Volumn 27, Issue 5, 2013, Pages 372-380

  Park, Se Jin ^a   Jun, Young Joon ^a   Kim, Tae Hoon ^a   Jung, Jong Yoon ^a   Hwang, Gyu Ho ^a   Jung, Kwang Jin ^a   Lee, Seung Hoon ^a   Lee, Heung Man ^a   Lee, Sang Hag ^a  

^a Korea University College of Medicine   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN; GAMMA INTERFERON; GELATINASE A; GELATINASE B; GLYCOPROTEIN; INTERLEUKIN 13; PROTEOGLYCAN; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TISSUE INHIBITOR OF METALLOPROTEINASE 2; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; YKL 40 PROTEIN;

ADULT; ARTICLE; CELL MIGRATION; CLINICAL ARTICLE; DISEASE SEVERITY; EPITHELIUM CELL; FEMALE; FIBROBLAST; HUMAN; IMMUNOHISTOCHEMISTRY; MALE; NOSE MUCOSA; PERENNIAL RHINITIS; PROTEIN ANALYSIS; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; TH2 CELL; WESTERN BLOTTING;

ADIPOKINES; ADULT; AIRWAY REMODELING; CELL LINE; CELL MOVEMENT; CELL PROLIFERATION; COLLAGEN; CYTOKINES; DISEASE PROGRESSION; EPITHELIAL CELLS; FEMALE; FIBROBLASTS; GROWTH SUBSTANCES; HUMANS; LECTINS; MALE; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; NASAL MUCOSA; RHINITIS, ALLERGIC, PERENNIAL; TH2 CELLS; TISSUE INHIBITOR OF METALLOPROTEINASE-1; UP-REGULATION;

EID: 84888405816     PISSN: 19458924     EISSN: 19458932     Source Type: Journal    
DOI: 10.2500/ajra.2013.27.3941     Document Type: Article

References (41)

1. Bousquet J, Chanez P, Lacoste JY, et al. Asthma: A disease remodeling the airways. Allergy 47:3-11, 1992.
2. Salib RJ, and Howarth PH. Remodeling of the upper airways in allergic rhinitis: Is it a feature of the disease? Clin Exp Allergy 33:1629-1633, 2003.
3. Bousquet J, Jacot W, Vignola AM, et al. Allergic rhinitis: A disease remodeling the upper airways? J Allergy Clin Immunol 113:43-49, 2004.
4. Watanabe K, and Kiuna C. Epithelial damage of nasal mucosa in nasal allergy. Ann Otol Rhinol Laryngol 107:564-570, 1998.
5. Sanai A, Nagata H, and Konno A, Extensive interstitial collagen deposition on the basement membrane zone in allergic nasal mucosa. Acta Otolaryngol 119:473-478, 1999.
6. Kim TH, Lee JY, Lee HM, et al. Remodeling of nasal mucosa in mild and severe persistent allergic rhinitis with special reference to the distribution of collagen, proteoglycans, and lymphatic vessels. Clin Exp Allergy 40:1742-1754, 2010.
7. Constantino Gde T, and Mello JF Jr. Remodeling of the lower and upper airways. Braz J Otorhinolaryngol 75:151-156, 2009.
8. Shaida A, Kenyon G, Devalia J, et al. Matrix metalloproteinases and their inhibitors in the nasal mucosa of patients with perennial allergic rhinitis. J Allergy Clin Immunol 108:791-796, 2001.
9. Kirmaz C, Ozbilgin K, Yuksel H, et al. Increased expression of angiogenic markers in patients with seasonal allergic rhinitis. Eur Cytokine Netw 15:317-322, 2004.
10. Lim YS, Won TB, Shim WS, et al. Induction of airway remodeling of nasal mucosa by repetitive allergen challenge in a murine model of allergic rhinitis. Ann Allergy Asthma Immunol 98:22-31, 2007.
11. Hua H, Zhang R, Yu S, et al. Tissue-type plasminogen activator depletion affects the nasal mucosa matrix reconstruction in allergic rhinitis mice. Allergol Immunopathol (Madr) 39:206-211, 2011.
12. Lee CG, Da Silva CA, Dela Cruz CS, et al. Role of chitin and chitinase/chitinase-like proteins in inflammation, tissue remodeling, and injury. Annu Rev Physiol 73:479-501, 2011.
13. Recklies AD, White C, and Ling H. The chitinase 3-like protein human cartilage glycoprotein 39 (HC-gp39) stimulates proliferation of human connective-tissue cells and activates both extracellular signal-regulated kinase- and protein kinase B-mediated signaling pathways. Biochem J 365:119-126, 2002.
14. Malinda KM, Ponce L, Kleinman HK, et al. GP38k, a protein synthesized by vascular smooth muscle cells, stimulates directional migration of human umbilical vein endothelial cells. Exp Cell Res 250:168-173, 1999.
15. Chupp GL, Lee CG, Jarjour N, et al. A chitinase-like protein in the lung and circulation of patients with severe asthma. N Engl J Med 357:2016-2027, 2007.
16. Furuhashi K, Suda T, Nakamura Y, et al. Increased expression of YKL-40, a chitinase-like protein, in serum and lung of patients with idiopathic pulmonary fibrosis. Respir Med 104:1204-1210, 2010.
17. Bousquet J, Van Cauwenberge P, and Khaltaev N. Allergic rhinitis and its impact on asthma. J Allergy Clin Immunol 108(suppl):S147-S334, 2001.
18. Lin Q, Fang LP, Zhou WW, and Liu XM. Resiglitazone inhibits migration, proliferation, and phenotypic differentiation in cultured human lung fibroblasts. Exp Lung Res 36:120-128, 2010.
19. Kwon JW, Kim TW, Cho SH, et al. Serum YKL-40 levels are correlated with symptom severity in patients with allergic rhinitis. Allergy 66:1252-1253, 2011.
20. Park SK, Hur DY, and Urm SH. Effects of dexamethasone or methotrexate on chitinolytic activity in nasal polyps. Am J Rhinol Allergy 26:183-186, 2012.
21. Park SK, Heo KW, Hur DY, and Yang YI. Chitinolytic activity in nasal polyps. Am J Rhinol Allergy 25:12-14, 2011.
22. Cho WS, Kim TH, Lee HM, et al. Increased expression of acidic mammalian chitinase and chitotriosidase in the nasal mucosa of patients with allergic rhinitis. Laryngoscope 120:870-875, 2010.
23. Rathcke CN, and Vestergaard H. YKL-40, a new inflammatory marker with relation to insulin resistance and with a role in endothelial dysfunction and atherosclerosis. Inflamm Res 55:221-227, 2006.
24. Mizoguchi E. Chitinase 3-like-1 exacerbates intestinal inflammation by enhancing bacterial adhesion and invasion in colonic epithelial cells. Gastroenterology 130:398-411, 2006.
25. Lee CG, Hartl D, Lee GR, et al. Role of breast regression protein 39 (BRP-39)/chitinase 3-like-1 in Th2 and IL-13-induced tissue responses and apoptosis. J Exp Med 206:1149-1166, 2009.
26. Bigg HF, Wait R, Rowan AD, and Cawston TE. The mammalian chitinase-like lectin, YKL-40, binds specifically to type I collagen and modulates the rate of type I collagen fibril formation. J Biol Chem 281:21082-21095, 2006.
27. Létuvé S, Kozhich A, Arouche N, et al. YKL-40 is elevated in patients with chronic obstructive pulmonary disease and activates alveolar macrophages. J Immunol 181:5167-5173, 2008.
28. De Ceuninck F, Gaufillier S, Bonnaud A, et al. YKL-40 (cartilage gp-39) induces proliferative events in cultured chondrocytes and synoviocytes and increases glycosaminoglycan synthesis in chondrocytes. Biochem Biophys Res Commun 285:926-931, 2001.
29. Watelet JB, Van Zele T, Gjomarkaj M, et al. Tissue remodelling in upper airways: Where is the link with lower airway remodelling? Allergy 61:1249-1258, 2006.
30. Westergren-Thorsson G, Chakir J, Lafrenière-Allard MJ, et al. Correlation between airway responsiveness and proteoglycan production by bronchial fibroblasts from normal and asthmatic subjects. Int J Biochem Cell Biol 34:1256-1267, 2002.
31. Gueders MM, Foidart JM, Noel A, and Cataldo DD. Matrix metalloproteinases (MMPs) and tissue inhibitors of MMPs in the respiratory tract: Potential implications in asthma and other lung diseases. Eur J Pharmacol 533:133-144, 2006.
32. Wang LF, Chien CY, Chiang FY, et al. Corelationship between matrix metalloproteinase 2 and 9 expression and severity of chronic rhinosinusitis with nasal polyposis. Am J Rhinol Allergy 26:e1-e4, 2012.
33. Kyo Y, Kanai K, Asano K, et al. Suppressive effect of fluticasone propionate on MMP expression in the nasal mucosa of allergic rhinitis patients in vivo. In Vivo 20:439-444, 2006.
34. Castano R, Miedinger D, Maghni K, et al. Matrix metalloproteinases and tissue inhibitors of metalloproteinases in nasal lavage after an inhalation challenge with flour. Laryngoscope 122:730-735, 2012.
35. van Toorenenbergen AW, Gerth van Wijk R, and Vermeulen AM. Allergen-induced matrix metalloproteinase-9 in nasal lavage fluid. Allergy 54:293-294, 1999.
36. Todorova L, Bjermer L, Westergren-Thorsson G, and Miller-Larsson A. TGFβ-induced matrix production by bronchial fibroblasts in asthma: Budesonide and formoterol effects. Respir Med 105:1296-1307, 2011.
37. Hallgren O, Nihlberg K, Dahlbäck M, et al. Altered fibroblast proteoglycan production in COPD. Respir Res 11:55, 2010.
38. Johansen JS, Olee T, Price PA, et al. Regulation of YKL-40 production by human articular chondrocytes. Arthritis Rheum 44:826-837, 2001.
39. Nielsen AR, Plomgaard P, Krabbe KS, et al. IL-6, but not TNF-α, increases plasma YKL-40 in human subjects. Cytokine 55:152-155, 2011.
40. Romagnani S, Parronchi P, D'Elios MM, et al. An update on human Th1 and Th2 cells. Int Arch Allergy Immunol 113:153-156, 1997.
41. Lee JH, Park KH, Park JW, and Hong CS. YKL-40 in induced sputum after allergen bronchial provocation in atopic asthma. J Investig Allergol Immunol 22:501-507, 2012.