The hydrogen-peroxide-induced radical behaviour in human cytochrome c-phospholipid complexes: Implications for the enhanced pro-apoptotic activity of the G41S mutant

Biochemical Journal

Volumn 456, Issue 3, 2013, Pages 441-452

  Rajagopal, Badri S ^a   Edzuma, Ann N ^a   Hough, Michael A ^a   Blundell, Katie L I M ^a   Kagan, Valerian E ^b   Kapralov, Alexandr A ^b   Fraser, Lewis A ^c   Butt, Julea N ^c   Silkstone, Gary G ^a   Wilson, Michael T ^a   Svistunenko, Dimitri A ^a   Worrall, Jonathan A R ^a  

^a UNIVERSITY OF ESSEX   (United Kingdom)

^b UNIVERSITY OF PITTSBURGH   (United States)

^c UNIVERSITY OF EAST ANGLIA   (United Kingdom)

Author keywords

Cardiolipin; Cytochrome c; Peroxidase; Phospholipid; Tyrosyl radical

Indexed keywords

CARDIOLIPIN; CYTOCHROME C; FREE RADICAL; HEME; HYDROGEN PEROXIDE; PEROXIDASE; PHOSPHOLIPID; TYROSINE;

APOPTOSIS; ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; ELECTRON SPIN RESONANCE; ENZYME ACTIVITY; ESCHERICHIA COLI; MUTATION; NONHUMAN; PRIORITY JOURNAL; WILD TYPE; X RAY; AMINO ACID SUBSTITUTION; CHEMISTRY; ENZYMOLOGY; GENETICS; HUMAN; METABOLISM; MISSENSE MUTATION; MITOCHONDRION;

AMINO ACID SUBSTITUTION; APOPTOSIS; CARDIOLIPINS; CYTOCHROMES C; ELECTRON SPIN RESONANCE SPECTROSCOPY; HUMANS; HYDROGEN PEROXIDE; MITOCHONDRIA; MUTATION, MISSENSE; PEROXIDASE;

EID: 84888402530     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20130758     Document Type: Article

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