The Role of Th17/Tc17 Peripheral Blood T cells in Psoriasis and Their Positive Therapeutic Response

Scandinavian Journal of Immunology

Volumn 78, Issue 6, 2013, Pages 529-537

  Eysteinsdottir J H ^a,b   Sigurgeirsson, B ^a   Olafsson J H ^a,b   Fridriksson, Th ^a   Agnarsson, B A ^b   Davisson S ^c   Valdimarsson, H ^a,b   Luviksson B R ^a,b  

^a UNIVERSITY OF ICELAND   (Iceland)

^b LANDSPITALI UNIVERSITY HOSPITAL   (Iceland)

^c Blue Lagoon Ltd   (Iceland)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CCR4; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 17; INTERLEUKIN 22; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 2; TUMOR NECROSIS FACTOR ALPHA;

ADULT; ARTICLE; BLOOD SAMPLING; CD8+ T LYMPHOCYTE; CELLULAR IMMUNITY; CLINICAL ARTICLE; DISEASE SEVERITY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; IMMUNOPATHOLOGY; INFLAMMATION; LYMPHOCYTE HOMING; MALE; PERIPHERAL BLOOD MONONUCLEAR CELL; PHENOTYPE; PRIORITY JOURNAL; PSORIASIS; PSORIASIS AREA AND SEVERITY INDEX; PUNCH BIOPSY; SKIN BIOPSY; SKIN IRRITATION; T LYMPHOCYTE; TH17 CELL; TREATMENT RESPONSE; ULTRAVIOLET B RADIATION; UNIVERSITY HOSPITAL;

ADULT; ANTIGENS, CD; BATHS; CD8-POSITIVE T-LYMPHOCYTES; DISEASE PROGRESSION; FEMALE; HOT SPRINGS; HUMANS; INTEGRIN ALPHA CHAINS; INTERFERON-GAMMA; INTERLEUKIN-17; INTERLEUKINS; LYMPHOCYTE COUNT; MALE; MIDDLE AGED; PSORIASIS; RECEPTORS, CCR10; SEAWATER; SKIN; TH1 CELLS; TH17 CELLS; TOLL-LIKE RECEPTORS; ULTRAVIOLET THERAPY;

EID: 84888396276     PISSN: 03009475     EISSN: 13653083     Source Type: Journal    
DOI: 10.1111/sji.12114     Document Type: Article

References (42)

1. Ingolfsdottir V, Beck HJ, Sigurdsson G, Magnusson G. The effect of bathing in the Blue Lagoon on the skin disease psoriasis. Landlaeknisembaettid (Directorate of Health in Iceland). Report (in Icelandic with English summary). 1989.
2. Olafsson JH, Sigurgeirsson B, Palsdottir R. The effect bathing in a thermal lagoon in Iceland has on psoriasis. J Eur Aad Dermatol Venerol 1994;3:460-4.
3. Gudmundsdottir AS, Sigmundsdottir H, Sigurgeirsson B, Good MF, Valdimarsson H, Jonsdottir I. Is an epitope on keratin 17 a major target for autoreactive T lymphocytes in psoriasis? Clin Exp Immunol 1999;117:580-6.
4. Johnston A, Arnadottir S, Gudjonsson JE et al. Obesity in psoriasis: leptin and resistin as mediators of cutaneous inflammation. Br J Dermatol 2008;159:342-50.
5. Olafsson JH, Sigurgeirsson B, Palsdottir R. Psoriasis treatment: bathing in a thermal lagoon combined with UVB, versus UVB treatment only. Acta Derm Venereol 1996;76:228-30.
6. Petursdottir SK, Kristjansson JK. The relationship between physical and chemical conditions and low microbial diversity in the Blue Lagoon geothermal lake in Iceland. FEMS Microbiol Ecol 1996;19:39-45.
7. Bjarnason J. Svartsengi. Chemical monitoring 1980-1987. National Energy Authority of Iceland Report OS-88001/JHD-01:98 (in Icelandic with English summary) 1988.
8. Grether-Beck S, Muhlberg K, Brenden H et al. Bioactive molecules from the Blue Lagoon: in vitro and in vivo assessment of silica mud and microalgae extracts for their effects on skin barrier function and prevention of skin ageing. Exp Dermatol 2008;17:771-9.
9. Nestle FO, Kaplan DH, Barker J. Psoriasis. N Engl J Med 2009;361:496-509.
10. Lowes MA, Kikuchi T, Fuentes-Duculan J et al. Psoriasis vulgaris lesions contain discrete populations of Th1 and Th17 T cells. J Invest Dermatol 2008;128:1207-11.
11. Kagami S, Rizzo HL, Lee JJ, Koguchi Y, Blauvelt A. Circulating Th17, Th22, and Th1 cells are increased in psoriasis. J Invest Dermatol 2010;130:1373-83.
12. Lonsdorf AS, Hwang ST, Enk AH. Chemokine receptors in T-cell-mediated diseases of the skin. J Invest Dermatol 2009;129:2552-66.
13. Teraki Y, Shiohara T. Preferential expression of alpha E beta 7 integrin (CD103) on CD8+T cells in the psoriatic epidermis: regulation by interleukins 4 and 12 and transforming growth factor-beta. Br J Dermatol 2002;147:1118-26.
14. Fredriksson T, Pettersson U. Severe psoriasis - Oral therapy with a new retinoid. Dermatologica 1978;157:238-44.
15. Menter A, Korman NJ, Elmets CA et al. Guidelines of care for the management of psoriasis and psoriatic arthritis: section 5. Guidelines of care for the treatment of psoriasis with phototherapy and photochemotherapy. J Am Acad Dermatol 2010;62:114-35.
16. Trozak DJ. Histologic grading system for psoriasis-vulgaris. Int J Dermatol 1994;33:380-1.
17. Griffiths CE, Richards HL. Psychological influences in psoriasis. Clin Exp Dermatol 2001;26:338-42.
18. Buske-Kirschbaum A, Kern S, Ebrecht M, Hellhammer DH. Altered distribution of leukocyte subsets and cytokine production in response to acute psychosocial stress in patients with psoriasis vulgaris. Brain Behav Immun 2007;21:92-9.
19. Abels DJ, Rose T, Bearman JE. Treatment of psoriasis at a Dead Sea dermatology clinic. Int J Dermatol 1995;34:134-7.
20. Even-Paz Z, Shani J. The Dead Sea and psoriasis. Historical and geographic background. Int J Dermatol 1989;28:1-9.
21. Kazandjieva J, Grozdev I, Darlenski R, Tsankov N. Climatotherapy of psoriasis. Clin Dermatol 2008;26:477-85.
22. Matz H, Orion E, Wolf R. Balneotherapy in dermatology. Dermatol Ther 2003;16:132-40.
23. Even-Paz Z, Gumon R, Kipnis V, Abels DJ, Efron D. Dead Sea sun versus Dead Sea water in the treatment of psoriasis. J Dermatol Treat 1996;7:83-6.
24. Dawe RS, Yule S, Cameron H, Moseley H, Ibbotson SH, Ferguson J. A randomized controlled comparison of the efficacy of Dead Sea salt balneophototherapy vs. narrowband ultraviolet B monotherapy for chronic plaque psoriasis. Br J Dermatol 2005;153:613-9.
25. Klein A, Schiffner R, Schiffner-Rohe J et al. A randomized clinical trial in psoriasis: synchronous balneophototherapy with bathing in Dead Sea salt solution plus narrowband UVB vs. narrowband UVB alone (TOMESA-study group). J Eur Acad Dermatol Venereol 2011;25:570-8.
26. Gambichler T, Demetriou C, Terras S, Bechara FG, Skrygan M. The impact of salt water soaks on biophysical and molecular parameters in psoriatic epidermis equivalents. Dermatology 2011;223:230-8.
27. Schempp CM, Blumke C, Schopf E, Simon JC. Skin sensitivity to UV-B radiation is differentially increased by exposure to water and different salt solutions. Arch Dermatol 1997;133:1610.
28. Celerier P, Richard A, Litoux P, Dreno B. Modulatory effects of selenium and strontium salts on keratinocyte-derived inflammatory cytokines. Arch Dermatol Res 1995;287:680-2.
29. Shani J, Sharon R, Koren R, Even-Paz Z. Effect of Dead-Sea brine and its main salts on cell growth in culture. Pharmacology 1987;35:339-47.
30. Boreham DR, Gasmann HC, Mitchel RE. Water bath hyperthermia is a simple therapy for psoriasis and also stimulates skin tanning in response to sunlight. Int J Hyperthermia 1995;11:745-54.
31. Wollenberg ARA, Bieber T. In vitro effect of the thermal water from La Roche Posay on the stimulatory capacity of epidermal Langerhans cells. Eur J Dermatol 1992;2:128-9.
32. Lee HP, Choi YJ, Cho KA et al. Effect of Spa spring water on cytokine expression in human keratinocyte HaCaT cells and on differentiation of CD4(+) T Cells. Ann Dermatol 2012;24:324-36.
33. Andrew DP, Ruffing N, Kim CH et al. C-C chemokine receptor 4 expression defines a major subset of circulating nonintestinal memory T cells of both Th1 and Th2 potential. J Immunol 2001;166:103-11.
34. Teraki Y, Miyake A, Takebayashi R, Shiohara T. Homing receptor and chemokine receptor on intraepidermal T cells in psoriasis vulgaris. Clin Exp Dermatol 2004;29:658-63.
35. Homey B, Alenius H, Muller A et al. CCL27-CCR10 interactions regulate T cell-mediated skin inflammation. Nat Med 2002;8:157-65.
36. Pauls K, Schon M, Kubitza RC et al. Role of integrin alphaE(CD103)beta7 for tissue-specific epidermal localization of CD8+ T lymphocytes. J Invest Dermatol 2001;117:569-75.
37. Soler D, Humphreys TL, Spinola SM, Campbell JJ. CCR4 versus CCR10 in human cutaneous TH lymphocyte trafficking. Blood 2003;101:1677-82.
38. Harper EG, Guo C, Rizzo H et al. Th17 cytokines stimulate CCL20 expression in keratinocytes in vitro and in vivo: implications for psoriasis pathogenesis. J Invest Dermatol 2009;129:2175-83.
39. Zhang L, Yang XQ, Cheng J, Hui RS, Gao TW. Increased Th17 cells are accompanied by FoxP3(+) Treg cell accumulation and correlated with psoriasis disease severity. Clin Immunol 2010;135:108-17.
40. Res PCM, Piskin G, de Boer OJ et al. Overrepresentation of IL-17A and IL-22 producing CD8 T cells in lesional skin suggests their involvement in the pathogenesis of psoriasis. PLoS ONE 2010;5. doi: 10.1371/journal.pone.0014108.
41. Johnson-Huang LM, Suarez-Farinas M, Sullivan-Whalen M, Gilleaudeau P, Krueger JG, Lowes MA. Effective narrow-band UVB radiation therapy suppresses the IL-23/IL-17 axis in normalized psoriasis plaques. J Invest Dermatol 2010;130:2654-63.
42. Begon E, Michel L, Flageul B et al. Expression, subcellular localization and cytokinic modulation of Toll-like receptors (TLRs) in normal human keratinocytes: TLR2 up-regulation in psoriatic skin. Eur J Dermatol 2007;17:497-506.