Inhibition of biofilms by glucose oxidase, lactoperoxidase and guaiacol: The active antibacterial component in an enzyme alginogel

International Wound Journal

Volumn 10, Issue 6, 2013, Pages 630-637

  Cooper, Rose A ^a  

^a CARDIFF METROPOLITAN UNIVERSITY   (United Kingdom)

Author keywords

Flaminal; Glucose oxidase; Guaiacol; Lactoperoxidase; Wounds

Indexed keywords

ANTIINFECTIVE AGENT; CRYSTAL VIOLET; FLAMINAL; FLUORESCEIN DIACETATE; GLUCOSE OXIDASE; GUAIACOL; LACTOPEROXIDASE; RESAZURIN; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ARTICLE; BACTERIAL VIABILITY; BIOFILM; BIOMASS; CONTROLLED STUDY; LEG ULCER; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; STAPHYLOCOCCUS AUREUS; DRUG EFFECTS; HUMAN; MICROBIAL SENSITIVITY TEST; MICROBIAL VIABILITY;

ANTI-BACTERIAL AGENTS; BIOFILMS; GLUCOSE OXIDASE; GUAIACOL; HUMANS; LACTOPEROXIDASE; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; MICROBIAL SENSITIVITY TESTS; MICROBIAL VIABILITY; PSEUDOMONAS AERUGINOSA;

EID: 84888338935     PISSN: 17424801     EISSN: 1742481X     Source Type: Journal    
DOI: 10.1111/iwj.12083     Document Type: Article

References (24)

1. de la Brassinne M, Thirion L, Horvat LI. A novel method of comparing the healing properties of two hydrogels in chronic leg ulcers. J Eur Acad Dermatol Venereol 2006;20:131-5.
2. Kyrlopoulos E, van den Plas D, Papadopoulos O, Papadopoulos S, Zapandioti P, Tsoutsos D. The use of a new wound alginogel for the treatment of partial-thickness hand burns. Wounds 2010;22:161-4.
3. Durante CM. An open-label non-comparative case series on the efficacy of an enzyme alginogel. J Wound Care 2012;21:22-7.
4. Vandenbulcke K, Horvat LI, de Mil M, Slegers G, Beele H. Evaluation of the antibacterial activity and toxicity of 2 new hydrogels: a pilot study. Int J Low Extrem Wounds 2006;5:109-14.
5. de Smet K, van den Plas D, Lens D, Sollie P. Pre-clinical evaluation of a new antimicrobial enzyme for the control of wound bioburden. Wounds 2009;21:65-73.
6. James GA, Swogger E, Wolcott R, Pulcini E, Secor P, Sestrich J, Costerton JW, Stewart PS. Biofilms in chronic wounds. Wound Repair Regen 2008;16:37-44.
7. Bjarnsholt T, Kirketerp-Møller K, Jensen PØ, Madsen KG, Phipps R, Krogfelt K, Høiby N, Givskov M. Why chronic wounds fail to heal: a new hypothesis. Wound Repair Regen 2008;16:2-10.
8. Stewart PS. Mechanisms of antibiotic resistance in bacterial biofilms. Int J Med Microbiol 2002;292:107-13.
9. Jakubovics NS, Kerrigan SW, Nobbs AH, Strömberg N, van Dollerweerd CJ, Cox DM, Kelly CG, Jenkinson HF. Functions of cell surface-anchored antigen I/II family and Hsa polypeptides in interactions of Streptococcus gordonii with host receptors. Infect Immun 2005;73:6629-38.
10. Peeters E, Nelis HJ, Coenye T. Comparison of multiple methods for quantification of microbial biofilms grown in microtitre plates. J Microbiol Methods 2008;72:157-65.
11. Thomas EL, Aune TM. Susceptibility of Escherichia coli to bactericidal action of lactoperoxidase, peroxide, and iodide or thiocyanate. Antimicrob Agents Chemother 1978;13:261-5.
12. Thomas EL, Milligan TW, Joyner RE, Jefferson MM. Antibacterial activity of hydrogen peroxide and the lactoperoxidase-hydrogen peroxide-thiocyanate system against oral streptococci. Infect Immun 1994;62:529-35.
13. Tenovuo J, Mäkinen KK, Sievers G. Antibacterial effect of lactoperoxidase and myeloperoxidase against Bacillus cereus. Antimicrob Agents Chemother 1985;27:96-101.
14. Murray EJ, Metcalfe CL, Nnamchi C, Moody PC, Raven EL. Crystal structure of guaiacol and phenol bound to a heme peroxidase. FEBS J 2012;279:1623-9.
15. Christensen GD, Simpson WA, Younger JJ, Baddour LM, Barrett FF, Melton DM, Beachey EH. Adherence of coagulase-negative staphylococci to plastic tissue culture plates: a quantitative model for the adherence of staphylococci to medical devices. J Clin Microbiol 1985;22:996-1006.
16. Stepanovic S, Vukovic D, Dakic I, Savic B, Svabic-Vlahovic M. A modified microtiter-plate test for quantification of staphylococcal biofilm formation. J Microbiol Methods 2000;40:175-9.
17. Merckoll P, Johassen TØ, Vad ME, Jeansson SL, Melby KK. Bacteria, biofilm and honey: a study of the effects of honey on 'planktonic' and biofilm-embedded chronic wound bacteria. Scand J Infect Dis 2009;41:341-7.
18. Maddocks SE, Lopez MS, Rowlands R, Cooper RA. Manuka honey inhibits the development of Streptococcus pyogenes biofilms and causes reduced expression of two fibronectin binding proteins. Microbiology 2012;158:781-90.
19. Johansen C, Falholt P, Gram L. Enzymatic removal and disinfection of bacterial biofilms. Appl Environ Microbiol 1997;63:3724-8.
20. Wolcott RD, Rhoads DD. A study of biofilm-based wound management in subjects with critical limb ischaemia. J Wound Care 2008;17:145-8 150-2, 154-5.
21. Wolcott RD, Rumbaugh KP, James G, Schultz G, Phillips P, Yang Q, Watters C, Stewart PS, Dowd SE. Biofilm maturity studies indicate sharp debridement opens a time-dependent therapeutic window. J Wound Care 2010;19:320-8.
22. Loo AEK, Ho R, Halliwell B. Mechanism of hydrogen peroxide-induced keratinocyte migration in a scratch model. Free Radic Biol Med 2011;51:884-92.
23. Loo AEK, Halliwell B. Effects of hydrogen peroxide in a keratinocyte-fibroblast co-culture model of wound healing. Biochem Biophys Res Commun 2012;423:253-8.
24. Kanta J. The role of hydrogen peroxide and other reactive oxygen species in wound healing. Acta Medica 2011;54:97-101.