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Volumn 58, Issue 6, 2013, Pages 1881-1884

Nuclear control of inflammation and fibrosis in nonalcoholic steatohepatitis: Therapeutic potential of dual peroxisome proliferator-activated receptor alpha/delta agonism

Author keywords

[No Author keywords available]

Indexed keywords

[2 METHYL 4 [4 METHYL 2 (4 TRIFLUOROMETHYLPHENYL) 5 THIAZOLYLMETHYLTHIO]PHENOXY]ACETIC ACID; ANTIFIBROTIC AGENT; COLLAGEN TYPE 1; GFT 505; INTERLEUKIN 1BETA; KD 3010; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR AGONIST; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA AGONIST; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA AGONIST; PIOGLITAZONE; ROSIGLITAZONE; TISSUE INHIBITOR OF METALLOPROTEINASE 2; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; 2-(2,6-DIMETHYL-4-(3-(4-(METHYLTHIO)PHENYL)-3-OXO-1-PROPENYL)PHENOXYL)-2-METHYLPROPANOIC ACID; CHALCONE DERIVATIVE; PROPIONIC ACID DERIVATIVE;

EID: 84888286333     PISSN: 02709139     EISSN: 15273350     Source Type: Journal    
DOI: 10.1002/hep.26582     Document Type: Article
Times cited : (10)

References (17)
  • 1
    • 84861591910 scopus 로고    scopus 로고
    • The diagnosis and management of non-alcoholic fatty liver disease: practice guideline by the American Gastroenterological Association, American Association for the Study of Liver Diseases, and American College of Gastroenterology
    • Chalasani N, Younossi Z, Lavine JE, Diehl AM, Brunt EM, Cusi K, et al. The diagnosis and management of non-alcoholic fatty liver disease: practice guideline by the American Gastroenterological Association, American Association for the Study of Liver Diseases, and American College of Gastroenterology. Gastroenterology 2012;142:1592-1609.
    • (2012) Gastroenterology , vol.142 , pp. 1592-1609
    • Chalasani, N.1    Younossi, Z.2    Lavine, J.E.3    Diehl, A.M.4    Brunt, E.M.5    Cusi, K.6
  • 2
    • 84880425040 scopus 로고    scopus 로고
    • Epidemiology and natural history of patients with NAFLD
    • doi: 10.2174/1381213233940916128.
    • Bhala N, Jouness RI, Bugianesi E. Epidemiology and natural history of patients with NAFLD. Curr Pharm Des 2013; doi: 10.2174/1381213233940916128.
    • (2013) Curr Pharm Des
    • Bhala, N.1    Jouness, R.I.2    Bugianesi, E.3
  • 3
    • 84879914319 scopus 로고    scopus 로고
    • Evolving aspects of liver transplantation for nonalcoholic steatohepatitis
    • Charlton M. Evolving aspects of liver transplantation for nonalcoholic steatohepatitis. Curr Opin Organ Transplant 2013;18:251-258.
    • (2013) Curr Opin Organ Transplant , vol.18 , pp. 251-258
    • Charlton, M.1
  • 4
    • 84878930738 scopus 로고    scopus 로고
    • Progression of NAFLD to diabetes mellitus, cardiovascular disease, or cirrhosis
    • Anstee QM, Targher G, Day CP. Progression of NAFLD to diabetes mellitus, cardiovascular disease, or cirrhosis. Nat Rev Gastroenterol Hepatol 2013;10:330-344.
    • (2013) Nat Rev Gastroenterol Hepatol , vol.10 , pp. 330-344
    • Anstee, Q.M.1    Targher, G.2    Day, C.P.3
  • 5
    • 84888285959 scopus 로고    scopus 로고
    • Hepato-protective effects of the dual PPARα/δ agonist gft505 in rodent models of NAFLD/NASH
    • Staels B, Rubenstrunk A, Noel B, Rigou G, Delataille P, Millatt LJ, et al. Hepato-protective effects of the dual PPARα/δ agonist gft505 in rodent models of NAFLD/NASH. Hepatology 2013;58:1941-1952.
    • (2013) Hepatology , vol.58 , pp. 1941-1952
    • Staels, B.1    Rubenstrunk, A.2    Noel, B.3    Rigou, G.4    Delataille, P.5    Millatt, L.J.6
  • 7
    • 84863104065 scopus 로고    scopus 로고
    • PPARs at the crossroads of lipid signaling and inflammation
    • Wahli W, Michalik L. PPARs at the crossroads of lipid signaling and inflammation. Trends Endocrinol Metab 2012;23:351-363.
    • (2012) Trends Endocrinol Metab , vol.23 , pp. 351-363
    • Wahli, W.1    Michalik, L.2
  • 8
    • 84872151568 scopus 로고    scopus 로고
    • Misregulation of PPAR Functioning and its pathogenic consequences associated with nonalcoholic fatty liver disease in human obesity
    • Videla LA, Pettinelli P. Misregulation of PPAR Functioning and its pathogenic consequences associated with nonalcoholic fatty liver disease in human obesity. PPAR Res 2012;2012:107434.
    • (2012) PPAR Res , vol.2012 , pp. 107434
    • Videla, L.A.1    Pettinelli, P.2
  • 9
    • 77949875356 scopus 로고    scopus 로고
    • Nuclear receptors, inflammation, and liver disease: insights for cholestatic and fatty liver diseases
    • Arrese M, Karpen SJ. Nuclear receptors, inflammation, and liver disease: insights for cholestatic and fatty liver diseases. Clin Pharmacol Ther 2010;87:473-478.
    • (2010) Clin Pharmacol Ther , vol.87 , pp. 473-478
    • Arrese, M.1    Karpen, S.J.2
  • 10
    • 77954239704 scopus 로고    scopus 로고
    • A meta-analysis of randomized trials for the treatment of nonalcoholic fatty liver disease
    • Musso G, Gambino R, Cassader M, Pagano G. A meta-analysis of randomized trials for the treatment of nonalcoholic fatty liver disease. Hepatology 2010;52:79-104.
    • (2010) Hepatology , vol.52 , pp. 79-104
    • Musso, G.1    Gambino, R.2    Cassader, M.3    Pagano, G.4
  • 11
    • 84871490319 scopus 로고    scopus 로고
    • Examining the safety of PPAR agonists - current trends and future prospects
    • Bortolini M, Wright MB, Bopst M, Balas B. Examining the safety of PPAR agonists - current trends and future prospects. Expert Opin Drug Saf 2013;12:65-79.
    • (2013) Expert Opin Drug Saf , vol.12 , pp. 65-79
    • Bortolini, M.1    Wright, M.B.2    Bopst, M.3    Balas, B.4
  • 13
    • 84875190733 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor delta: a multifaceted metabolic player
    • Bojic LA, Huff MW. Peroxisome proliferator-activated receptor delta: a multifaceted metabolic player. Curr Opin Lipidol 2013;24:171-177.
    • (2013) Curr Opin Lipidol , vol.24 , pp. 171-177
    • Bojic, L.A.1    Huff, M.W.2
  • 15
    • 84870946722 scopus 로고    scopus 로고
    • GW501516-activated PPARbeta/delta promotes liver fibrosis via p38-JNK MAPK-induced hepatic stellate cell proliferation
    • Kostadinova R, Montagner A, Gouranton E, Fleury S, Guillou H, Dombrowicz D, et al. GW501516-activated PPARbeta/delta promotes liver fibrosis via p38-JNK MAPK-induced hepatic stellate cell proliferation. Cell Biosci 2012;2:34.
    • (2012) Cell Biosci , vol.2 , pp. 34
    • Kostadinova, R.1    Montagner, A.2    Gouranton, E.3    Fleury, S.4    Guillou, H.5    Dombrowicz, D.6
  • 17
    • 84885405205 scopus 로고    scopus 로고
    • Dual peroxisome proliferator-activated receptor alpha/delta agonist GFT505 improves hepatic and peripheral insulin sensitivity in abdominally obese subjects
    • Cariou B, Hanf R, Lambert-Porcheron S, Zair Y, Sauvinet V, Noel B, et al. Dual peroxisome proliferator-activated receptor alpha/delta agonist GFT505 improves hepatic and peripheral insulin sensitivity in abdominally obese subjects. Diabetes Care 2013 (in press).
    • (2013) Diabetes Care
    • Cariou, B.1    Hanf, R.2    Lambert-Porcheron, S.3    Zair, Y.4    Sauvinet, V.5    Noel, B.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.