Protective effect of hydroferrate fluid, MRN-100, against lethality and hematopoietic tissue damage in γ-Radiated Nile tilapia, Oreochromis niloticus

Journal of Radiation Research

Volumn 54, Issue 5, 2013, Pages 852-862

  Ghoneum, Mamdooh ^a   Elbaghdady, Heba Allah M ^b   El shebly, Abdallah A ^c   Pan, Deyu ^a   Assanah, Edward ^a   Lawson, Greg ^d  

^a CHARLES R DREW UNIVERSITY OF MEDICINE AND SCIENCE   (United States)

^b Mansoura University   (Egypt)

^c NATIONAL INSTITUTE OF OCEANOGRAPHY AND FISHERIES   (Egypt)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Hydroferrate fluid; Oreochromis niloticus; Sadiation; Survival

Indexed keywords

BLOOD; CELLS; HISTOLOGY; IRON COMPOUNDS; RADIATION EFFECTS; TISSUE;

EXPOSED TO; HYDROFERRATE FLUID; NILE TILAPIA; OREOCHROMIS NILOTICUS; PROTECTIVE EFFECTS; RED BLOOD CELL; SADIATION; SURVIVAL; SURVIVAL RATE; WHITE BLOOD CELLS;

FISH;

OREOCHROMIS NILOTICUS;

ANTIOXIDANT; FERRATE ION; IRON; RADIOPROTECTIVE AGENT;

ANIMAL; ARTICLE; CICHLID; DOSE RESPONSE; DRUG EFFECT; GAMMA RADIATION; HEMATOLOGIC DISEASE; HYDROFERRATE FLUID; MORTALITY; OREOCHROMIS NILOTICUS; PATHOLOGY; PREVALENCE; RADIATION; RADIATION DOSE; RADIATION INJURY; RADIATION RESPONSE; RISK FACTOR; SURVIVAL; SURVIVAL RATE; TREATMENT OUTCOME; UNITED STATES;

HYDROFERRATE FLUID; OREOCHROMIS NILOTICUS; RADIATION; SURVIVAL;

ANIMALS; ANTIOXIDANTS; CALIFORNIA; CICHLIDS; DOSE-RESPONSE RELATIONSHIP, DRUG; DOSE-RESPONSE RELATIONSHIP, RADIATION; GAMMA RAYS; HEMATOLOGIC DISEASES; IRON; PREVALENCE; RADIATION INJURIES; RADIATION TOLERANCE; RADIATION-PROTECTIVE AGENTS; RISK FACTORS; SURVIVAL RATE; TREATMENT OUTCOME;

EID: 84888226077     PISSN: 04493060     EISSN: 13499157     Source Type: Journal    
DOI: 10.1093/jrr/rrt029     Document Type: Article

References (61)

1. Uma DP. Radiosensitivity of the developing haemopoietic system in mammals and its adult consequences: animal studies. Br J Radiol 2003;76:366-72
2. Fliedner TM, Graessle D-H. Hematopoietic cell renewal systems: mechanisms of coping and failing after chronic exposure to ionizing radiation. Radiat Environ Biophys 2008;47:63-9
3. Kalpana KB, Devipriya N, Srinivasan M et al. Evaluating the radioprotective effect of hesperidin in the liver of Swiss albino mice. Eur J Pharmacol 2011;658:206-12
4. Weiss JF. Pharmacologic approaches to protection against radiation-induced lethality and other damage. Environ Health Perspect 1997;105:1473-8
5. Ghoneum M, Badr El-Din NK, Abdel Fattah SM et al. (3 January 2013) Arabinoxylan rice bran (MGN-3/Biobran) provides protection against whole-body gamma-irradiation in mice via restoration of hematopoietic tissues. J Radiat Res, 10.1093/jrr/rrs119
6. Landauer MR, Srinivasan V, Seed TM. Genistein treatment protects mice from ionizing radiation injury. J Appl Toxicol 2003;23:379-85
7. Jagetia GC, Venkatesh P, Baliga MS. Evaluation of the radioprotective effect of bael leaf (Aegle marmelos) extract in mice. Int J Radiat Biol 2004;80:281-90
8. Kim HJ, Kim MH, Byon YY et al. Radioprotective effects of an acidic polysaccharide of Panax ginseng on bone marrow cells. J Vet Sci 2007;8:39-44
9. Park E, Ahn GN, Lee NH et al. Radioprotective properties of eckol against ionizing radiation in mice. Febs Lett 2008;582:925-30
10. Bichay TJ, Roy RM. Modification of survival and hematopoiesis in mice by tocopherol injection following irradiation. Strahlenther Onkol 1986;162:391-9
11. Srinivasan V, Weiss JF. Radioprotection by Vitamin E: injectable Vitamin E administered alone or with WR-3689 enhances survival of irradiated mice. Int J Radiat Oncol Biol Phys 1992;23:841-5
12. Sarma L, Kesavan PC. Protective effects of vitamins C and E against gamma ray-induced chromosomal damage in mouse. Int J Radiat Biol 1993;63:759-64
13. Badr El-Din NK, Noaman E, EL-Banna SM et al. Reversal of age-associated oxidative stress in rats by MRN-100, a hydro-ferrate fluid. In Vivo 2010;24:525-34
14. Ghoneum M, Egami N, Ijiri K. Effects of acute gamma-irradiation on the development of the thymus in embryos and fry of Oryzias latipes. Int J Radiat Biol Relat Stud Phys Chem Med 1981;39:339-44
15. Ghoneum M, Egami N. Effect of X-irradiation on adult and embryo of Oryzias latipes on thymous size. In: Egami N (ed). Radiation Effects of Aquatic Organisms. Baltimore, MD: University Park Press, 1980, 135-7
16. Ghoneum M, Egami N, Ijiri K. Effect of oestrogen treatment on the survival of irradiated fish of the species Oryzias latipes. Folia Morphol 1988;36:25-31
17. Simon O, Massarin S, Coppin F et al. Investigating the embryo/larval toxic and genotoxic effects of ? irradiation on zebrafish eggs. J Environ Radioact 2011;102:1039-44
18. Arts MT, Browman HI, Jokinen IE et al. Effects of UV radiation and diet on polyunsaturated fatty acids in the skin, ocular tissue and dorsal muscle of Atlantic salmon (Salmo salar) held in outdoor rearing tanks. Photochem Photobiol 2012;86:909-19
19. Warrier SB, Ninjoor V, Sawant PL et al. Differential release of latent lysosomal hydrolases in muscle of Tilapia mossambica by whole body gamma radiation. Indian J Biochem Biophys 1972;9:278-9
20. Ghoneum M, Matsuura M, Gollapudi S. An iron-based beverage, HydroFerrate fluid (MRN-100), alleviates oxidative stress in murine lymphocytes in vitro. Nutrition J 2009:8:18
21. Ghoneum M, Shaheen M. MRN-100, an iron-based compound, possesses anti-HIV activity in vitro. Evid Based Complement Alternat Med 2010;7:427-32
22. Gaikowski MP, Wolf JC, Schleis SM et al. (26 October 2012) Safety of florfenicol administered in feed to tilapia (Oreochromis sp.). Toxicol Pathol
23. Jerônimo GT, Laffitte LV, Speck GM et al. Seasonal influence on the hematological parameters in cultured Nile tilapia from southern Brazil. Braz J Biol 2011;71:719-25
24. Tort L, Rotllant J, Rovira L. Immunological suppression in gilthead sea bream Sparus aurata of the North West Mediterranean at low temperature. Comp Biochem Physiol A 1998;120:175-9
25. Morgan AL, Thompson KD, Auchinachie NA et al. The effect of seasonality on normal haematological and innate immune parameters of rainbow trout Oncorhynchus mykiss L. Fish Shellfish Immunol 2008;25:791-9
26. Pascoli F, Lanzano GS, Negrato E et al. Seasonal effects on hematological and innate immune parameters in sea bass Dicentrarchus labrax. Fish Shellfish Immunol 2011;31:1081-7
27. Stolen JS, Gahn T, Kasper V et al. The effect of environmental temperature on the immune response of a marine teleost (Faralichrhys denrufus). Dev Comp Immunol 1984;8:89-98
28. Anno GH, Young RW, Bloom RM et al. Dose response relationships for acute ionizing-radiation lethality. Health Phys 2003;84:565-75
29. Casarett AP, American Institute of Biological Sciences. Radiation Biology. American Institute of Biological Sciences, U.S. Atomic Energy Commission (eds), University of California: Prentice Hall Inc., 1968, 158-9
30. Karran P. DNA double strand break repair in mammalian cells. Curr Opin Genet Dev 2000;10:144-50
31. Bhosle SM, Huilgol NG, Mishra KP. Enhancement of radiation-induced oxidative stress and cytotoxicity in tumor cells by ellagic acid. Clin Chim Acta 2005;359:89-100
32. Lee JH, Lee YM, Park JW. Regulation of ionizing radiation-induced apoptosis by a manganese porphyrin complex. Biochem Biophys Res Commun 2005;334:298-305
33. Ghoneum M, Ijiri K, Egami N. Effects of gamma-rays on morphology of the thymus of the adult fish of Oryzias latipes. J Radiat Res 1982;23:253-9
34. Assayed ME. Radioprotective effects of black seed (Nigella sativa) oil against hemopoietic damage and immunosuppression in gamma-irradiated rats. Immunopharmacol Immunotoxicol 2010;32:284-96
35. Yang R, Pei X, Wang J et al. Protective effect of a marine oligopeptide preparation from chum salmon (Oncorhynchus keta) on radiation-induced immune suppression in mice. J Sci Food Agric 2010;90:2241-8
36. Ghoneum M, Kijima Y. Induction of human natural killer (NK) cell activity by pi-water (MRN-100). Annual Conference on Clinical Immunology, New Orleans, LA, 1996
37. Ghoneum M, Namatalla G, Kijima Y. Phenotypic analysis of human lymphocyte sub-populations post treatment with pi-water (MRN-100). In: Abstracts and Proceedings of the Eighty-eighth Annual Meeting of the American Association for Cancer Research, San Diego, CA, 1997
38. Ghoneum M. NK immunorestoration in cancer patients by MRN-100, an iron based compound derived from bivalent and trivalent ferrate. Fourth International Symposium on Predictive Oncology and Therapy, Nice, France, 1998
39. Herberman RB, Djeu J, Kay HD et al. Natural killer cells: characteristics and regulation of activity. Immunol Rev 1979;44:43-70
40. Koepsell SA, Miller JS, McKenna DH, Jr. Natural killer cells: A review of manufacturing and clinical utility. Transfusion 2013;53:404-10
41. Agius C, Agbede SA. An electron microscopical study on the genesis of lipofuscin, melanin and haemosiderin in the haemopoietic tissues of fish. J Fish Biol 1984:24:471-88
42. Chukhlovin AB. Apoptosis and red blood cell echinocytosis: common features. Scanning Microsc 1996;10:795-804
43. Gridley DS, Miller GM, Pecaut MJ. Radiation and primary response to lipopolysaccharide: bone marrow-derived cells and susceptible organs. In Vivo 2007;21:453-61
44. Latifi A, Jeanjean R, Lemeille S et al. Iron starvation leads to oxidative stress in Anabaena sp. strain PCC 7120. J Bacteriol 2005;187:6596-8
45. Udipi S, Ghugre P, Gokhale C. Iron, Oxidative Stress and Health. In: Lushchak V, Semchyshyn HM (eds). Oxidative Stress Molecular Mechanisms and biological effects. Open Access: INTECH, 2012, 147-8
46. Balla G, Jacob HS, Balla J et al. Ferritin: a cytoprotective antioxidant strategem of endothelium. J Biol Chem 1992;267:18148-53
47. Halliwell B, Gutteridge JM. Biologically relevant metal iondependent hydroxyl radical generation. An update. FEBS Lett 1992;307:108-12
48. Garrick MD, Garrick LM. Cellular iron transport. Biochim Biophys Acta 2009;1790:309-25
49. Pourahmad J, Shaki F, Tanbakosazan F et al. Protective effects of fungal β-(1(Proteglucan against oxidative stress cytotoxicity induced by depleted uranium in isolated rat hepatocytes. Hum Exp Toxicol 2011;30:173-81
50. El-Habit OH, Saada HN, Azab KS et al. The modifying effect of beta-carotene on gamma radiation-induced elevation of oxidative reactions and genotoxicity in male rats. Mutat Res 2000;466:179-86
51. Al Kaddissi S, Legeay A, Elia AC et al. Effects of uranium on crayfish Procambarus clarkii mitochondria and antioxidants responses after chronic exposure: what have we learned? Ecotoxicol Environ Saf 2012;78:218-24
52. Jiang WD, Wu P, Kuang SY et al. Myo-inositol prevents copperinduced oxidative damage and changes in antioxidant capacity in various organs and the enterocytes of juvenile Jian carp (Cyprinus carpio var. Jian). Aquat Toxicol 2011;105:543-51
53. Li XY, Zeng SH, Dong XY et al. Acute toxicity and responses of antioxidant systems to 1-methyl-3-octylimidazolium bromide at different developmental stages of goldfish. Ecotoxicology 2012;21:253-9
54. Robbins MEC, Zhao W. Chronic oxidative stress and radiation- Induced late normal tissue injury: a review. Int J Radiat Biol 2004;80:251-9
55. Sangsuwan T, Haghdoost S. The nucleotide pool, a target for low-dose ?-ray-induced oxidative stress. Radiat Res 2008;170:776-83
56. Datta K, Suman S, Kallakury BVS et al. (24 August 2012) Exposure to heavy ion radiation induces persistent oxidative stress in mouse intestine. PLoS ONE, 10.1371/journal. pone.0042224
57. Waller AR, Worsdworth OJ. Long term liver radiation damage in the rat following internal and external irradiation. Aust J Exp Biol Med Sci 1974;52:387-95
58. Ren Z-G, Zhao J-D, Gu K et al. Hepatic proliferation after partial liver irradiation in Sprague-Dawley rats. Mol Biol Rep 2012;39:3829-36
59. Mouiseddine M, Francois S, Souidi M et al. Intravenous human mesenchymal stem cells transplantation in NOD/SCID mice preserve liver integrity of irradiation damage. Methods Mol Biol 2012;826:179-188
60. Wang TJ, Liu ZS, Zeng ZC et al. Caffeine does not enhance radiosensitivity of normal liver tissue in vivo. Mol Biol Rep 2011;38:4359-67
61. Adaramoye OA, Okiti OO, Farombi EO. Dried fruit extract from Xylopia aethiopica (Annonaceae) protects Wistar albino rats from adverse effects of whole body radiation. Exp Toxicol Pathol 2011;63:635-43