메뉴 건너뛰기




Volumn 24, Issue SUPPL.10, 2013, Pages

Ovarian cancer: Genomic analysis

Author keywords

Cancer; Clinical trials; Genomics; Ovarian

Indexed keywords

B RAF KINASE; EPIDERMAL GROWTH FACTOR RECEPTOR 2; K RAS PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE;

EID: 84888213232     PISSN: 09237534     EISSN: 15698041     Source Type: Journal    
DOI: 10.1093/annonc/mdt462     Document Type: Article
Times cited : (31)

References (75)
  • 1
    • 84871036375 scopus 로고    scopus 로고
    • Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010
    • Lozano R, Naghavi M, Foreman K et al. Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet 2012; 380: 2095-2128.
    • (2012) Lancet , vol.380 , pp. 2095-2128
    • Lozano, R.1    Naghavi, M.2    Foreman, K.3
  • 3
    • 66549084297 scopus 로고    scopus 로고
    • Non-epithelial ovarian cancer: ESMO clinical recommendations for diagnosis, treatment and follow-up
    • Colombo N, Peiretti M, Castiglione M. Non-epithelial ovarian cancer: ESMO clinical recommendations for diagnosis, treatment and follow-up. Ann Oncol 2009; 20 (Suppl 4):24-26.
    • (2009) Ann Oncol , vol.20 , Issue.SUPPL. 4 , pp. 24-26
    • Colombo, N.1    Peiretti, M.2    Castiglione, M.3
  • 4
    • 84858342785 scopus 로고    scopus 로고
    • Carcinosarcoma of the ovary: a review of the literature
    • del Carmen MG, Birrer M, Schorge JO. Carcinosarcoma of the ovary: a review of the literature. Gynecol Oncol 2012; 125: 271-277.
    • (2012) Gynecol Oncol , vol.125 , pp. 271-277
    • del Carmen, M.G.1    Birrer, M.2    Schorge, J.O.3
  • 5
    • 0036498788 scopus 로고    scopus 로고
    • Survival effect of maximal cytoreductive surgery for advanced ovarian carcinoma during the platinum era: a meta-analysis
    • Bristow RE, Tomacruz RS, Armstrong DK et al. Survival effect of maximal cytoreductive surgery for advanced ovarian carcinoma during the platinum era: a meta-analysis. J Clin Oncol 2002; 20: 1248-1259.
    • (2002) J Clin Oncol , vol.20 , pp. 1248-1259
    • Bristow, R.E.1    Tomacruz, R.S.2    Armstrong, D.K.3
  • 6
    • 77954986199 scopus 로고    scopus 로고
    • Cytoreductive surgery plus chemotherapy versus chemotherapy alone for recurrent epithelial ovarian cancer
    • CD007822.
    • Galaal K, Naik R, Bristow RE et al. Cytoreductive surgery plus chemotherapy versus chemotherapy alone for recurrent epithelial ovarian cancer. Cochrane Database Syst Rev 2010; CD007822.
    • (2010) Cochrane Database Syst Rev
    • Galaal, K.1    Naik, R.2    Bristow, R.E.3
  • 7
    • 84882454584 scopus 로고    scopus 로고
    • Survival impact of complete cytoreduction to no gross residual disease for advanced-stage ovarian cancer: a meta-analysis
    • Chang SJ, Hodeib M, Chang J et al. Survival impact of complete cytoreduction to no gross residual disease for advanced-stage ovarian cancer: a meta-analysis. Gynecol Oncol 2013; 130: 493-498.
    • (2013) Gynecol Oncol , vol.130 , pp. 493-498
    • Chang, S.J.1    Hodeib, M.2    Chang, J.3
  • 8
    • 84866952001 scopus 로고    scopus 로고
    • Does tumour biology determine surgical success in the treatment of epithelial ovarian cancer? A systematic literature review
    • Borley J, Wilhelm-Benartzi C, Brown R et al. Does tumour biology determine surgical success in the treatment of epithelial ovarian cancer? A systematic literature review. Br J Cancer 2012; 107: 1069-1074.
    • (2012) Br J Cancer , vol.107 , pp. 1069-1074
    • Borley, J.1    Wilhelm-Benartzi, C.2    Brown, R.3
  • 9
    • 0043240182 scopus 로고    scopus 로고
    • Ovarian cancer: strategies for overcoming resistance to chemotherapy
    • Agarwal R, Kaye SB. Ovarian cancer: strategies for overcoming resistance to chemotherapy. Nat Rev Cancer 2003; 3: 502-516.
    • (2003) Nat Rev Cancer , vol.3 , pp. 502-516
    • Agarwal, R.1    Kaye, S.B.2
  • 10
    • 56749098120 scopus 로고    scopus 로고
    • Associations between p53 overexpression and multiple measures of clinical outcome in high-risk, early stage or suboptimally-resected, advanced stage epithelial ovarian cancers A Gynecologic Oncology Group study
    • Darcy KM, Brady WE, McBroom JW et al. Associations between p53 overexpression and multiple measures of clinical outcome in high-risk, early stage or suboptimally-resected, advanced stage epithelial ovarian cancers A Gynecologic Oncology Group study. Gynecol Oncol 2008; 111: 487-495.
    • (2008) Gynecol Oncol , vol.111 , pp. 487-495
    • Darcy, K.M.1    Brady, W.E.2    McBroom, J.W.3
  • 11
    • 67349095676 scopus 로고    scopus 로고
    • Associations between ERBB2 amplification and progression-free survival and overall survival in advanced stage, suboptimallyresected epithelial ovarian cancers: a Gynecologic Oncology Group Study
    • Farley J, Fuchiuji S, Darcy KM et al. Associations between ERBB2 amplification and progression-free survival and overall survival in advanced stage, suboptimallyresected epithelial ovarian cancers: a Gynecologic Oncology Group Study. Gynecol Oncol 2009; 113: 341-347.
    • (2009) Gynecol Oncol , vol.113 , pp. 341-347
    • Farley, J.1    Fuchiuji, S.2    Darcy, K.M.3
  • 12
    • 0035123775 scopus 로고    scopus 로고
    • Precursor lesions of ovarian epithelial malignancy
    • Feeley KM, Wells M. Precursor lesions of ovarian epithelial malignancy. Histopathology 2001; 38: 87-95.
    • (2001) Histopathology , vol.38 , pp. 87-95
    • Feeley, K.M.1    Wells, M.2
  • 13
    • 41349095074 scopus 로고    scopus 로고
    • Grading of ovarian cancer: a histotype-specific approach
    • Malpica A. Grading of ovarian cancer: a histotype-specific approach. Int J Gynecol Pathol 2008; 27: 175-181.
    • (2008) Int J Gynecol Pathol , vol.27 , pp. 175-181
    • Malpica, A.1
  • 14
    • 84861896210 scopus 로고    scopus 로고
    • Reclassification of serous ovarian carcinoma by a 2-tier system: a Gynecologic Oncology Group Study
    • Bodurka DC, Deavers MT, Tian C et al. Reclassification of serous ovarian carcinoma by a 2-tier system: a Gynecologic Oncology Group Study. Cancer 2012; 118: 3087-3094.
    • (2012) Cancer , vol.118 , pp. 3087-3094
    • Bodurka, D.C.1    Deavers, M.T.2    Tian, C.3
  • 15
    • 33645759727 scopus 로고    scopus 로고
    • Ovarian epithelial tumors of low malignant potential: are they precursors of ovarian carcinoma?
    • Fukumoto M, Nakayama K. Ovarian epithelial tumors of low malignant potential: are they precursors of ovarian carcinoma? Pathol Int 2006; 56: 233-239.
    • (2006) Pathol Int , vol.56 , pp. 233-239
    • Fukumoto, M.1    Nakayama, K.2
  • 16
    • 47949086341 scopus 로고    scopus 로고
    • Utilization of a uniform grading system for interpreting serous ovarian cancer
    • Lachance JA, Shutter J, Atkins KA et al. Utilization of a uniform grading system for interpreting serous ovarian cancer. Am J Obstet Gynecol 2008; 199: 189. e1-189.e6.
    • (2008) Am J Obstet Gynecol , vol.199
    • Lachance, J.A.1    Shutter, J.2    Atkins, K.A.3
  • 17
    • 28544452713 scopus 로고    scopus 로고
    • Expression profiling of serous low malignant potential, low-grade, and high-grade tumors of the ovary
    • Bonome T, Lee JY, Park DC et al. Expression profiling of serous low malignant potential, low-grade, and high-grade tumors of the ovary. Cancer Res 2005; 65: 10602-10612.
    • (2005) Cancer Res , vol.65 , pp. 10602-10612
    • Bonome, T.1    Lee, J.Y.2    Park, D.C.3
  • 18
    • 33645274637 scopus 로고    scopus 로고
    • A distinct molecular profile associated with mucinous epithelial ovarian cancer
    • Heinzelmann-Schwarz VA, Gardiner-Garden M, Henshall SM et al. A distinct molecular profile associated with mucinous epithelial ovarian cancer. Br J Cancer 2006; 94: 904-913.
    • (2006) Br J Cancer , vol.94 , pp. 904-913
    • Heinzelmann-Schwarz, V.A.1    Gardiner-Garden, M.2    Henshall, S.M.3
  • 19
    • 0037102445 scopus 로고    scopus 로고
    • Gene expression in ovarian cancer reflects both morphology and biological behavior, distinguishing clear cell from other poor-prognosis ovarian carcinomas
    • Schwartz DR, Kardia SL, Shedden KA et al. Gene expression in ovarian cancer reflects both morphology and biological behavior, distinguishing clear cell from other poor-prognosis ovarian carcinomas. Cancer Res 2002; 62: 4722-4729.
    • (2002) Cancer Res , vol.62 , pp. 4722-4729
    • Schwartz, D.R.1    Kardia, S.L.2    Shedden, K.A.3
  • 20
    • 20144387395 scopus 로고    scopus 로고
    • Histologic type, organ of origin, and Wnt pathway status: effect on gene expression in ovarian and uterine carcinomas
    • Shedden KA, Kshirsagar MP, Schwartz DR et al. Histologic type, organ of origin, and Wnt pathway status: effect on gene expression in ovarian and uterine carcinomas. Clin Cancer Res 2005; 11: 2123-2131.
    • (2005) Clin Cancer Res , vol.11 , pp. 2123-2131
    • Shedden, K.A.1    Kshirsagar, M.P.2    Schwartz, D.R.3
  • 21
    • 79959923767 scopus 로고    scopus 로고
    • Identification of novel therapeutic targets in microdissected clear cell ovarian cancers
    • e21121
    • Stany MP, Vathipadiekal V, Ozbun L et al. Identification of novel therapeutic targets in microdissected clear cell ovarian cancers. PLoS One 2011; 6: e21121-
    • (2011) PLoS One , vol.6
    • Stany, M.P.1    Vathipadiekal, V.2    Ozbun, L.3
  • 22
    • 32944481884 scopus 로고    scopus 로고
    • Expression profiling of mucinous tumors of the ovary identifies genes of clinicopathologic importance
    • Wamunyokoli FW, Bonome T, Lee JY et al. Expression profiling of mucinous tumors of the ovary identifies genes of clinicopathologic importance. Clin Cancer Res 2006; 12: 690-700.
    • (2006) Clin Cancer Res , vol.12 , pp. 690-700
    • Wamunyokoli, F.W.1    Bonome, T.2    Lee, J.Y.3
  • 23
    • 34047171574 scopus 로고    scopus 로고
    • Mouse model of human ovarian endometrioid adenocarcinoma based on somatic defects in the Wnt/beta-catenin and PI3 K/Pten signaling pathways
    • Wu R, Hendrix-Lucas N, Kuick R et al. Mouse model of human ovarian endometrioid adenocarcinoma based on somatic defects in the Wnt/beta-catenin and PI3 K/Pten signaling pathways. Cancer Cell 2007; 11: 321-333.
    • (2007) Cancer Cell , vol.11 , pp. 321-333
    • Wu, R.1    Hendrix-Lucas, N.2    Kuick, R.3
  • 24
    • 25144523393 scopus 로고    scopus 로고
    • Gene expression profiles of serous, endometrioid, and clear cell subtypes of ovarian and endometrial cancer
    • Zorn KK, Bonome T, Gangi L et al. Gene expression profiles of serous, endometrioid, and clear cell subtypes of ovarian and endometrial cancer. Clin Cancer Res 2005; 11: 6422-6430.
    • (2005) Clin Cancer Res , vol.11 , pp. 6422-6430
    • Zorn, K.K.1    Bonome, T.2    Gangi, L.3
  • 25
    • 79959838081 scopus 로고    scopus 로고
    • Integrated genomic analyses of ovarian carcinoma
    • Cancer Genome Atlas Research Network
    • Cancer Genome Atlas Research Network. Integrated genomic analyses of ovarian carcinoma. Nature 2011; 474: 609-615.
    • (2011) Nature , vol.474 , pp. 609-615
  • 26
    • 0025944479 scopus 로고
    • K-ras activation occurs frequently in mucinous adenocarcinomas and rarely in other common epithelial tumors of the human ovary
    • Enomoto T, Weghorst CM, Inoue M et al. K-ras activation occurs frequently in mucinous adenocarcinomas and rarely in other common epithelial tumors of the human ovary. Am J Pathol 1991; 139: 777-785.
    • (1991) Am J Pathol , vol.139 , pp. 777-785
    • Enomoto, T.1    Weghorst, C.M.2    Inoue, M.3
  • 27
    • 0042624835 scopus 로고    scopus 로고
    • Role of KRAS and BRAF gene mutations in mucinous ovarian carcinoma
    • Gemignani ML, Schlaerth AC, Bogomolniy F et al. Role of KRAS and BRAF gene mutations in mucinous ovarian carcinoma. Gynecol Oncol 2003; 90: 378-381.
    • (2003) Gynecol Oncol , vol.90 , pp. 378-381
    • Gemignani, M.L.1    Schlaerth, A.C.2    Bogomolniy, F.3
  • 28
    • 0037454224 scopus 로고    scopus 로고
    • Mutations in BRAF and KRAS characterize the development of low-grade ovarian serous carcinoma
    • Singer G, Oldt R, III, Cohen Y et al. Mutations in BRAF and KRAS characterize the development of low-grade ovarian serous carcinoma. J Natl Cancer Inst 2003; 95: 484-486.
    • (2003) J Natl Cancer Inst , vol.95 , pp. 484-486
    • Singer, G.1    Oldt III, R.2    Cohen, Y.3
  • 29
    • 0033609680 scopus 로고    scopus 로고
    • beta-catenin mutation and expression analysis in ovarian cancer: exon 3 mutations and nuclear translocation in 16% of endometrioid tumours
    • Wright K, Wilson P, Morland S et al. beta-catenin mutation and expression analysis in ovarian cancer: exon 3 mutations and nuclear translocation in 16% of endometrioid tumours. Int J Cancer 1999; 82: 625-629.
    • (1999) Int J Cancer , vol.82 , pp. 625-629
    • Wright, K.1    Wilson, P.2    Morland, S.3
  • 30
    • 0032523808 scopus 로고    scopus 로고
    • Frequent PTEN/MMAC mutations in endometrioid but not serous or mucinous epithelial ovarian tumors
    • Obata K, Morland SJ, Watson RH et al. Frequent PTEN/MMAC mutations in endometrioid but not serous or mucinous epithelial ovarian tumors. Cancer Res 1998; 58: 2095-2097.
    • (1998) Cancer Res , vol.58 , pp. 2095-2097
    • Obata, K.1    Morland, S.J.2    Watson, R.H.3
  • 31
    • 65649128979 scopus 로고    scopus 로고
    • Frequent activating mutations of PIK3CA in ovarian clear cell carcinoma
    • Kuo KT, Mao TL, Jones S et al. Frequent activating mutations of PIK3CA in ovarian clear cell carcinoma. Am J Pathol 2009; 174: 1597-1601.
    • (2009) Am J Pathol , vol.174 , pp. 1597-1601
    • Kuo, K.T.1    Mao, T.L.2    Jones, S.3
  • 32
    • 7444250290 scopus 로고    scopus 로고
    • Mutation of the PIK3CA gene in ovarian and breast cancer
    • Campbell IG, Russell SE, Choong DY et al. Mutation of the PIK3CA gene in ovarian and breast cancer. Cancer Res 2004; 64: 7678-7681.
    • (2004) Cancer Res , vol.64 , pp. 7678-7681
    • Campbell, I.G.1    Russell, S.E.2    Choong, D.Y.3
  • 33
    • 79955473637 scopus 로고    scopus 로고
    • Clear cell carcinoma of the ovary: a report from the first Ovarian Clear Cell Symposium, June 24th, 2010
    • Anglesio MS, Carey MS, Kobel M et al. Clear cell carcinoma of the ovary: a report from the first Ovarian Clear Cell Symposium, June 24th, 2010. Gynecol Oncol 2011; 121: 407-415.
    • (2011) Gynecol Oncol , vol.121 , pp. 407-415
    • Anglesio, M.S.1    Carey, M.S.2    Kobel, M.3
  • 34
    • 77957731999 scopus 로고    scopus 로고
    • Frequent mutations of chromatin remodeling gene ARID1A in ovarian clear cell carcinoma
    • Jones S, Wang TL, Shih I et al. Frequent mutations of chromatin remodeling gene ARID1A in ovarian clear cell carcinoma. Science 2010; 330: 228-231.
    • (2010) Science , vol.330 , pp. 228-231
    • Jones, S.1    Wang, T.L.2    Shih, I.3
  • 35
    • 77957946398 scopus 로고    scopus 로고
    • ARID1A mutations in endometriosisassociated ovarian carcinomas
    • Wiegand KC, Shah SP, Al-Agha OM et al. ARID1A mutations in endometriosisassociated ovarian carcinomas. N Engl J Med 2010; 363: 1532-1543.
    • (2010) N Engl J Med , vol.363 , pp. 1532-1543
    • Wiegand, K.C.1    Shah, S.P.2    Al-Agha, O.M.3
  • 36
  • 37
    • 79954570471 scopus 로고    scopus 로고
    • IL6-STAT3-HIF signaling and therapeutic response to the angiogenesis inhibitor sunitinib in ovarian clear cell cancer
    • Anglesio MS, George J, Kulbe H et al. IL6-STAT3-HIF signaling and therapeutic response to the angiogenesis inhibitor sunitinib in ovarian clear cell cancer. Clin Cancer Res 2011; 17: 2538-2548.
    • (2011) Clin Cancer Res , vol.17 , pp. 2538-2548
    • Anglesio, M.S.1    George, J.2    Kulbe, H.3
  • 38
    • 80051696232 scopus 로고    scopus 로고
    • Ovarian clear cell carcinoma as a stressresponsive cancer: influence of the microenvironment on the carcinogenesis and cancer phenotype
    • Mandai M, Matsumura N, Baba T et al. Ovarian clear cell carcinoma as a stressresponsive cancer: influence of the microenvironment on the carcinogenesis and cancer phenotype. Cancer Lett 2011; 310: 129-133.
    • (2011) Cancer Lett , vol.310 , pp. 129-133
    • Mandai, M.1    Matsumura, N.2    Baba, T.3
  • 39
    • 34250020187 scopus 로고    scopus 로고
    • Sunitinib: a novel tyrosine kinase inhibitor. A brief review of its therapeutic potential in the treatment of renal carcinoma and gastrointestinal stromal tumors (GIST)
    • Le TC, Raymond E, Faivre S. Sunitinib: a novel tyrosine kinase inhibitor. A brief review of its therapeutic potential in the treatment of renal carcinoma and gastrointestinal stromal tumors (GIST). Ther Clin Risk Manag 2007; 3: 341-348.
    • (2007) Ther Clin Risk Manag , vol.3 , pp. 341-348
    • Le, T.C.1    Raymond, E.2    Faivre, S.3
  • 40
    • 51749119466 scopus 로고    scopus 로고
    • Potential benefit of Sunitinib in recurrent and refractory ovarian clear cell adenocarcinoma
    • Rauh-Hain JA, Penson RT. Potential benefit of Sunitinib in recurrent and refractory ovarian clear cell adenocarcinoma. Int J Gynecol Cancer 2008; 18: 934-936.
    • (2008) Int J Gynecol Cancer , vol.18 , pp. 934-936
    • Rauh-Hain, J.A.1    Penson, R.T.2
  • 41
    • 57649231823 scopus 로고    scopus 로고
    • Therapeutic strategy targeting the mTORHIF- 1alpha-VEGF pathway in ovarian clear cell adenocarcinoma
    • Miyazawa M, Yasuda M, Fujita M et al. Therapeutic strategy targeting the mTORHIF- 1alpha-VEGF pathway in ovarian clear cell adenocarcinoma. Pathol Int 2009; 59: 19-27.
    • (2009) Pathol Int , vol.59 , pp. 19-27
    • Miyazawa, M.1    Yasuda, M.2    Fujita, M.3
  • 42
    • 84857081287 scopus 로고    scopus 로고
    • Weekly administration of temsirolimus for heavily pretreated patients with clear cell carcinoma of the ovary: a report of six cases
    • Takano M, Kikuchi Y, Kudoh K et al. Weekly administration of temsirolimus for heavily pretreated patients with clear cell carcinoma of the ovary: a report of six cases. Int J Clin Oncol 2011; 16: 605-609.
    • (2011) Int J Clin Oncol , vol.16 , pp. 605-609
    • Takano, M.1    Kikuchi, Y.2    Kudoh, K.3
  • 43
    • 84862884719 scopus 로고    scopus 로고
    • Ovarian low-grade serous carcinoma: a comprehensive update
    • Daz-Padilla I, Malpica AL, Minig L et al. Ovarian low-grade serous carcinoma: a comprehensive update. Gynecol Oncol 2012; 126: 279-285.
    • (2012) Gynecol Oncol , vol.126 , pp. 279-285
    • Daz-Padilla, I.1    Malpica, A.L.2    Minig, L.3
  • 44
    • 33748122161 scopus 로고    scopus 로고
    • Clinical behavior of stage II-IV low-grade serous carcinoma of the ovary
    • Gershenson DM, Sun CC, Lu KH et al. Clinical behavior of stage II-IV low-grade serous carcinoma of the ovary. Obstet Gynecol 2006; 108: 361-368.
    • (2006) Obstet Gynecol , vol.108 , pp. 361-368
    • Gershenson, D.M.1    Sun, C.C.2    Lu, K.H.3
  • 45
    • 13944279557 scopus 로고    scopus 로고
    • Molecular and prognostic distinction between serous ovarian carcinomas of varying grade and malignant potential
    • Meinhold-Heerlein I, Bauerschlag D, Hilpert F et al. Molecular and prognostic distinction between serous ovarian carcinomas of varying grade and malignant potential. Oncogene 2005; 24: 1053-1065.
    • (2005) Oncogene , vol.24 , pp. 1053-1065
    • Meinhold-Heerlein, I.1    Bauerschlag, D.2    Hilpert, F.3
  • 46
    • 77949306418 scopus 로고    scopus 로고
    • Low malignant potential tumors with micropapillary features are molecularly similar to low-grade serous carcinoma of the ovary
    • May T, Virtanen C, Sharma M et al. Low malignant potential tumors with micropapillary features are molecularly similar to low-grade serous carcinoma of the ovary. Gynecol Oncol 2010; 117: 9-17.
    • (2010) Gynecol Oncol , vol.117 , pp. 9-17
    • May, T.1    Virtanen, C.2    Sharma, M.3
  • 47
    • 56449104265 scopus 로고    scopus 로고
    • Mutation of ERBB2 provides a novel alternative mechanism for the ubiquitous activation of RAS-MAPK in ovarian serous low malignant potential tumors
    • Anglesio MS, Arnold JM, George J et al. Mutation of ERBB2 provides a novel alternative mechanism for the ubiquitous activation of RAS-MAPK in ovarian serous low malignant potential tumors. Mol Cancer Res 2008; 6: 1678-1690.
    • (2008) Mol Cancer Res , vol.6 , pp. 1678-1690
    • Anglesio, M.S.1    Arnold, J.M.2    George, J.3
  • 48
    • 52649085237 scopus 로고    scopus 로고
    • Novel molecular subtypes of serous and endometrioid ovarian cancer linked to clinical outcome
    • Tothill RW, Tinker AV, George J et al. Novel molecular subtypes of serous and endometrioid ovarian cancer linked to clinical outcome. Clin Cancer Res 2008; 14: 5198-5208.
    • (2008) Clin Cancer Res , vol.14 , pp. 5198-5208
    • Tothill, R.W.1    Tinker, A.V.2    George, J.3
  • 49
    • 84873079682 scopus 로고    scopus 로고
    • Selumetinib in women with recurrent low-grade serous carcinoma of the ovary or peritoneum: an open-label, singlearm, phase 2 study
    • Farley J, Brady WE, Vathipadiekal V et al. Selumetinib in women with recurrent low-grade serous carcinoma of the ovary or peritoneum: an open-label, singlearm, phase 2 study. Lancet Oncol 2013; 14: 134-140.
    • (2013) Lancet Oncol , vol.14 , pp. 134-140
    • Farley, J.1    Brady, W.E.2    Vathipadiekal, V.3
  • 50
    • 39249083491 scopus 로고    scopus 로고
    • Neoadjuvant chemotherapy for low-grade serous carcinoma of the ovary or peritoneum
    • Schmeler KM, Sun CC, Bodurka DC et al. Neoadjuvant chemotherapy for low-grade serous carcinoma of the ovary or peritoneum. Gynecol Oncol 2008; 108: 510-514.
    • (2008) Gynecol Oncol , vol.108 , pp. 510-514
    • Schmeler, K.M.1    Sun, C.C.2    Bodurka, D.C.3
  • 51
    • 84864053120 scopus 로고    scopus 로고
    • BRCAness: finding the Achilles heel in ovarian cancer
    • Rigakos G, Razis E. BRCAness: finding the Achilles heel in ovarian cancer. Oncologist 2012; 17: 956-962.
    • (2012) Oncologist , vol.17 , pp. 956-962
    • Rigakos, G.1    Razis, E.2
  • 52
    • 67650471685 scopus 로고    scopus 로고
    • Inhibition of poly(ADP-ribose) polymerase in tumors from BRCA mutation carriers
    • Fong PC, Boss DS, Yap TA et al. Inhibition of poly(ADP-ribose) polymerase in tumors from BRCA mutation carriers. N Engl J Med 2009; 361: 123-134.
    • (2009) N Engl J Med , vol.361 , pp. 123-134
    • Fong, P.C.1    Boss, D.S.2    Yap, T.A.3
  • 53
    • 77954032829 scopus 로고    scopus 로고
    • Poly(ADP)-ribose polymerase inhibition: frequent durable responses in BRCA carrier ovarian cancer correlating with platinum-free interval
    • Fong PC, Yap TA, Boss DS et al. Poly(ADP)-ribose polymerase inhibition: frequent durable responses in BRCA carrier ovarian cancer correlating with platinum-free interval. J Clin Oncol 2010; 28: 2512-2519.
    • (2010) J Clin Oncol , vol.28 , pp. 2512-2519
    • Fong, P.C.1    Yap, T.A.2    Boss, D.S.3
  • 54
    • 81155152247 scopus 로고    scopus 로고
    • PARP inhibitors in BRCA gene-mutated ovarian cancer and beyond
    • Banerjee S, Kaye S. PARP inhibitors in BRCA gene-mutated ovarian cancer and beyond. Curr Oncol Rep 2011; 13: 442-449.
    • (2011) Curr Oncol Rep , vol.13 , pp. 442-449
    • Banerjee, S.1    Kaye, S.2
  • 55
    • 84883054717 scopus 로고    scopus 로고
    • A Phase 1 trial of the poly(ADP-ribose) polymerase inhibitor olaparib (AZD2281) in combination with the anti-angiogenic cediranib (AZD2171) in recurrent epithelial ovarian or triple-negative breast cancer
    • Liu JF, Tolaney SM, Birrer M et al. A Phase 1 trial of the poly(ADP-ribose) polymerase inhibitor olaparib (AZD2281) in combination with the anti-angiogenic cediranib (AZD2171) in recurrent epithelial ovarian or triple-negative breast cancer. Eur J Cancer 2013.
    • (2013) Eur J Cancer
    • Liu, J.F.1    Tolaney, S.M.2    Birrer, M.3
  • 56
    • 0346368077 scopus 로고    scopus 로고
    • Gene expression patterns that characterize advanced stage serous ovarian cancers
    • Lancaster JM, Dressman HK, Whitaker RS et al. Gene expression patterns that characterize advanced stage serous ovarian cancers. J Soc Gynecol Investig 2004; 11: 51-59.
    • (2004) J Soc Gynecol Investig , vol.11 , pp. 51-59
    • Lancaster, J.M.1    Dressman, H.K.2    Whitaker, R.S.3
  • 57
    • 21044455139 scopus 로고    scopus 로고
    • Patterns of gene expression that characterize long-term survival in advanced stage serous ovarian cancers
    • Berchuck A, Iversen ES, Lancaster JM et al. Patterns of gene expression that characterize long-term survival in advanced stage serous ovarian cancers. Clin Cancer Res 2005; 11: 3686-3696.
    • (2005) Clin Cancer Res , vol.11 , pp. 3686-3696
    • Berchuck, A.1    Iversen, E.S.2    Lancaster, J.M.3
  • 58
    • 70749118578 scopus 로고    scopus 로고
    • A gene signature predictive for outcome in advanced ovarian cancer identifies a survival factor: microfibril-associated glycoprotein 2
    • Mok SC, Bonome T, Vathipadiekal V et al. A gene signature predictive for outcome in advanced ovarian cancer identifies a survival factor: microfibril-associated glycoprotein 2. Cancer Cell 2009; 16: 521-532.
    • (2009) Cancer Cell , vol.16 , pp. 521-532
    • Mok, S.C.1    Bonome, T.2    Vathipadiekal, V.3
  • 59
    • 0033532072 scopus 로고    scopus 로고
    • Microfibril-associated glycoprotein-2 specifically interacts with a range of bovine and human cell types via alphaVbeta3 integrin
    • Gibson MA, Leavesley DI, Ashman LK. Microfibril-associated glycoprotein-2 specifically interacts with a range of bovine and human cell types via alphaVbeta3 integrin. J Biol Chem 1999; 274: 13060-13065.
    • (1999) J Biol Chem , vol.274 , pp. 13060-13065
    • Gibson, M.A.1    Leavesley, D.I.2    Ashman, L.K.3
  • 60
    • 0042072994 scopus 로고    scopus 로고
    • Adhesion of endothelial cells to NOV is mediated by the integrins alphavbeta3 and alpha5beta1
    • Ellis PD, Metcalfe JC, Hyvonen M et al. Adhesion of endothelial cells to NOV is mediated by the integrins alphavbeta3 and alpha5beta1. J Vasc Res 2003; 40: 234-243.
    • (2003) J Vasc Res , vol.40 , pp. 234-243
    • Ellis, P.D.1    Metcalfe, J.C.2    Hyvonen, M.3
  • 61
    • 84873619713 scopus 로고    scopus 로고
    • Targeted anti-vascular therapies for ovarian cancer: current evidence
    • Hall M, Gourley C, McNeish I et al. Targeted anti-vascular therapies for ovarian cancer: current evidence. Br J Cancer 2013; 108: 250-258.
    • (2013) Br J Cancer , vol.108 , pp. 250-258
    • Hall, M.1    Gourley, C.2    McNeish, I.3
  • 62
    • 84855425106 scopus 로고    scopus 로고
    • Incorporation of bevacizumab in the primary treatment of ovarian cancer
    • Burger RA, Brady MF, Bookman MA et al. Incorporation of bevacizumab in the primary treatment of ovarian cancer. N Engl J Med 2011; 365: 2473-2483.
    • (2011) N Engl J Med , vol.365 , pp. 2473-2483
    • Burger, R.A.1    Brady, M.F.2    Bookman, M.A.3
  • 63
    • 84855466019 scopus 로고    scopus 로고
    • A phase 3 trial of bevacizumab in ovarian cancer
    • Perren TJ, Swart AM, Pfisterer J et al. A phase 3 trial of bevacizumab in ovarian cancer. N Engl J Med 2011; 365: 2484-2496.
    • (2011) N Engl J Med , vol.365 , pp. 2484-2496
    • Perren, T.J.1    Swart, A.M.2    Pfisterer, J.3
  • 64
    • 34250200790 scopus 로고    scopus 로고
    • Whole genome oligonucleotide-based array comparative genomic hybridization analysis identified fibroblast growth factor 1 as a prognostic marker for advanced-stage serous ovarian adenocarcinomas
    • Birrer MJ, Johnson ME, Hao K et al. Whole genome oligonucleotide-based array comparative genomic hybridization analysis identified fibroblast growth factor 1 as a prognostic marker for advanced-stage serous ovarian adenocarcinomas. J Clin Oncol 2007; 25: 2281-2287.
    • (2007) J Clin Oncol , vol.25 , pp. 2281-2287
    • Birrer, M.J.1    Johnson, M.E.2    Hao, K.3
  • 65
    • 84885056979 scopus 로고    scopus 로고
    • FGF18 as a prognostic and therapeutic biomarker in ovarian cancer
    • Wei et al. FGF18 as a prognostic and therapeutic biomarker in ovarian cancer. J Clin Invest 2013; 123(10): 4435-4448.
    • (2013) J Clin Invest , vol.123 , Issue.10 , pp. 4435-4448
    • Wei, W.1
  • 66
    • 12344267687 scopus 로고    scopus 로고
    • Gene expression signature with independent prognostic significance in epithelial ovarian cancer
    • Spentzos D, Levine DA, Ramoni MF et al. Gene expression signature with independent prognostic significance in epithelial ovarian cancer. J Clin Oncol 2004; 22: 4700-4710.
    • (2004) J Clin Oncol , vol.22 , pp. 4700-4710
    • Spentzos, D.1    Levine, D.A.2    Ramoni, M.F.3
  • 67
    • 34250821793 scopus 로고    scopus 로고
    • Macrophages mediate inflammation-enhanced metastasis of ovarian tumors in mice
    • Robinson-Smith TM, Isaacsohn I, Mercer CA et al. Macrophages mediate inflammation-enhanced metastasis of ovarian tumors in mice. Cancer Res 2007; 67: 5708-5716.
    • (2007) Cancer Res , vol.67 , pp. 5708-5716
    • Robinson-Smith, T.M.1    Isaacsohn, I.2    Mercer, C.A.3
  • 68
    • 77949529738 scopus 로고    scopus 로고
    • Immunopathogenesis of ovarian cancer
    • Thompson MS, Mok SC. Immunopathogenesis of ovarian cancer. Minerva Med 2009; 100: 357-370.
    • (2009) Minerva Med , vol.100 , pp. 357-370
    • Thompson, M.S.1    Mok, S.C.2
  • 69
    • 84857073155 scopus 로고    scopus 로고
    • Genome wide DNA copy number analysis of serous type ovarian carcinomas identifies genetic markers predictive of clinical outcome
    • Engler DA, Gupta S, Growdon WB et al. Genome wide DNA copy number analysis of serous type ovarian carcinomas identifies genetic markers predictive of clinical outcome. PLoS One 2012; 7: e30996.
    • (2012) PLoS One , vol.7
    • Engler, D.A.1    Gupta, S.2    Growdon, W.B.3
  • 70
    • 75149170979 scopus 로고    scopus 로고
    • Fibroblast growth factor signalling: from development to cancer
    • Turner N, Grose R. Fibroblast growth factor signalling: from development to cancer. Nat Rev Cancer 2010; 10: 116-129.
    • (2010) Nat Rev Cancer , vol.10 , pp. 116-129
    • Turner, N.1    Grose, R.2
  • 71
    • 79955667838 scopus 로고    scopus 로고
    • Targeting mutant fibroblast growth factor receptors in cancer
    • Greulich H, Pollock PM. Targeting mutant fibroblast growth factor receptors in cancer. Trends Mol Med 2011; 17: 283-292.
    • (2011) Trends Mol Med , vol.17 , pp. 283-292
    • Greulich, H.1    Pollock, P.M.2
  • 72
    • 84876103735 scopus 로고    scopus 로고
    • Blockade of nonhormonal fibroblast growth factors by FP-1039 inhibits growth of multiple types of cancer
    • Harding TC, Long L, Palencia S et al. Blockade of nonhormonal fibroblast growth factors by FP-1039 inhibits growth of multiple types of cancer. Sci Transl Med 2013; 5: 178ra39.
    • (2013) Sci Transl Med , vol.5
    • Harding, T.C.1    Long, L.2    Palencia, S.3
  • 73
    • 80053561888 scopus 로고    scopus 로고
    • Randomized phase II placebo-controlled trial of maintenance therapy using the oral triple angiokinase inhibitor BIBF 1120 after chemotherapy for relapsed ovarian cancer
    • Ledermann JA, Hackshaw A, Kaye S et al. Randomized phase II placebo-controlled trial of maintenance therapy using the oral triple angiokinase inhibitor BIBF 1120 after chemotherapy for relapsed ovarian cancer. J Clin Oncol 2011; 29: 3798-3804.
    • (2011) J Clin Oncol , vol.29 , pp. 3798-3804
    • Ledermann, J.A.1    Hackshaw, A.2    Kaye, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.