메뉴 건너뛰기




Volumn 7, Issue 12, 2013, Pages 2248-2258

Comparative metatranscriptomics reveals kingdom level changes in the rhizosphere microbiome of plants

Author keywords

metatranscriptomics; microbiome; oat; pea; rhizosphere; wheat

Indexed keywords

TRANSCRIPTOME;

EID: 84888203902     PISSN: 17517362     EISSN: 17517370     Source Type: Journal    
DOI: 10.1038/ismej.2013.119     Document Type: Article
Times cited : (429)

References (62)
  • 2
    • 0032911917 scopus 로고    scopus 로고
    • The membrane-permeabilizing effect of avenacin A-1 involves the reorganization of bilayer cholesterol
    • Armah CN, Mackie AR, Roy C, Price K, Osbourn AE, Bowyer P et al. (1999). the membrane-permeabilizing effect of avenacin A-1 involves the reorganization of bilayer cholesterol. Biophys J 76: 281-290 (Pubitemid 29202456)
    • (1999) Biophysical Journal , vol.76 , Issue.1 , pp. 281-290
    • Armah, C.N.1    Mackie, A.R.2    Roy, C.3    Price, K.4    Osbourn, A.E.5    Bowyer, P.6    Ladha, S.7
  • 5
    • 0034932568 scopus 로고    scopus 로고
    • Molecular basis of plant growth promotion and biocontrol by rhizobacteria
    • DOI 10.1016/S1369-5266(00)00183-7
    • Bloemberg GV, Lugtenberg BJJ. (2001). Molecular basis of plant growth promotion and biocontrol by rhizobacteria. Curr Opin Plant Biol 4: 343-350 (Pubitemid 32620718)
    • (2001) Current Opinion in Plant Biology , vol.4 , Issue.4 , pp. 343-350
    • Bloemberg, G.V.1    Lugtenberg, B.J.J.2
  • 8
    • 84863981120 scopus 로고    scopus 로고
    • Ultra-high-throughput microbial community analysis on the Illumina HiSeq and MiSeq platforms
    • Caporaso JG, Lauber CL, Walters WA, Berg-Lyons D, Huntley J, Fierer N et al. (2012). Ultra-high-throughput microbial community analysis on the Illumina HiSeq and MiSeq platforms. ISME J 6: 1621-1624
    • (2012) ISME J , vol.6 , pp. 1621-1624
    • Caporaso, J.G.1    Lauber, C.L.2    Walters, W.A.3    Berg-Lyons, D.4    Huntley, J.5    Fierer, N.6
  • 9
    • 0032772095 scopus 로고    scopus 로고
    • Isolation, characterization, and avenacin sensitivity of a diverse collection of cereal-root-colonizing fungi
    • Carter JP, Spink J, Cannon PF, Daniels MJ, Osbourn AE. (1999). Isolation, characterization, and avenacin sensitivity of a diverse collection of cereal-rootcolonizing fungi. Appl Environ Microbiol 65: 3364-3372 (Pubitemid 29398958)
    • (1999) Applied and Environmental Microbiology , vol.65 , Issue.8 , pp. 3364-3372
    • Carter, J.P.1    Spink, J.2    Cannon, P.F.3    Daniels, M.J.4    Osbourn, A.E.5
  • 10
    • 58149200948 scopus 로고    scopus 로고
    • The Ribosomal Database Project: Improved alignments and new tools for rRNA analysis
    • Cole JR, Wang Q, Cardenas E, Fish J, Chai B, Farris RJ et al. (2009). the Ribosomal Database Project: improved alignments and new tools for rRNA analysis. Nucleic Acids Res 37: D141-D145
    • (2009) Nucleic Acids Res , vol.37
    • Cole, J.R.1    Wang, Q.2    Cardenas, E.3    Fish, J.4    Chai, B.5    Farris, R.J.6
  • 12
    • 77951949012 scopus 로고    scopus 로고
    • Are root exudates more important than other sources of rhizodeposits in structuring rhizosphere bacterial communities?
    • Dennis PG, Miller AJ, Hirsch PR. (2010). Are root exudates more important than other sources of rhizodeposits in structuring rhizosphere bacterial communities? FEMS Microbiol Ecol 72: 313-327
    • (2010) FEMS Microbiol Ecol , vol.72 , pp. 313-327
    • Dennis, P.G.1    Miller, A.J.2    Hirsch, P.R.3
  • 13
    • 77949881304 scopus 로고    scopus 로고
    • Phylogenomics of sterol synthesis insights into the origin, evolution, and diversity of a key eukaryotic feature
    • Desmond E, Gribaldo S. (2009). Phylogenomics of sterol synthesis: insights into the origin, evolution, and diversity of a key eukaryotic feature. Genome Biol Evol 1: 364-381
    • (2009) Genome Biol Evol , vol.1 , pp. 364-381
    • Desmond, E.1    Gribaldo, S.2
  • 14
    • 0345802561 scopus 로고    scopus 로고
    • Hydrogen fertilization of soils - Is this a benefit of legumes in rotation?
    • DOI 10.1046/j.1365-3040.2003.01103.x
    • Dong Z, Wu L, Kettlewell B, Caldwell CD, Layzell DB. (2003). Hydrogen fertilization of soils-is this a benefit of legumes in rotation? Plant Cell Environ 26: 1875-1879 (Pubitemid 38024741)
    • (2003) Plant, Cell and Environment , vol.26 , Issue.11 , pp. 1875-1879
    • Dong, Z.1    Wu, L.2    Kettlewell, B.3    Caldwell, C.D.4    Layzell, D.B.5
  • 15
    • 37649024043 scopus 로고    scopus 로고
    • The ade4 package: Implementing the duality diagram for ecologists
    • Dray S, Dufour AB. (2007). the ade4 package: Implementing the duality diagram for ecologists. J Statist Softw 22: 1-20
    • (2007) J Statist Softw , vol.22 , pp. 1-20
    • Dray, S.1    Dufour, A.B.2
  • 16
    • 77957244650 scopus 로고    scopus 로고
    • Search and clustering orders of magnitude faster than BLAST
    • Edgar RC. (2010). Search and clustering orders of magnitude faster than BLAST. Bioinformatics 26: 2460-2461
    • (2010) Bioinformatics , vol.26 , pp. 2460-2461
    • Edgar, R.C.1
  • 18
    • 0036847978 scopus 로고    scopus 로고
    • The production of methanol by flowering plants and the global cycle of methanol
    • DOI 10.1023/A:1020684815474
    • Galbally IE, Kirstine W. (2002). the production of methanol by flowering plants and the global cycle of methanol. J Atmos Chem 43: 195-229 (Pubitemid 35331279)
    • (2002) Journal of Atmospheric Chemistry , vol.43 , Issue.3 , pp. 195-229
    • Galbally, I.E.1    Kirstine, W.2
  • 19
    • 70350294348 scopus 로고    scopus 로고
    • Systematic artifacts in metagenomes from complex microbial communities
    • Gomez-Alvarez V, Teal TK, Schmidt TM. (2009). Systematic artifacts in metagenomes from complex microbial communities. ISME J 3: 1314-1317
    • (2009) ISME J , vol.3 , pp. 1314-1317
    • Gomez-Alvarez, V.1    Teal, T.K.2    Schmidt, T.M.3
  • 21
    • 79951606290 scopus 로고    scopus 로고
    • Complete genome sequence of the metabolically versatile plant growth-promoting endophyte variovorax paradoxus S110
    • Han JI, Choi HK, Lee SW, Orwin PM, Kim J, Laroe SL et al. (2011). Complete genome sequence of the metabolically versatile plant growth-promoting endophyte variovorax paradoxus S110 J Bacteriol 193: 1183-1190
    • (2011) J Bacteriol , vol.193 , pp. 1183-1190
    • Han, J.I.1    Choi, H.K.2    Lee, S.W.3    Orwin, P.M.4    Kim, J.5    Laroe, S.L.6
  • 22
    • 10344227692 scopus 로고    scopus 로고
    • Metagenomics: Application of genomics to uncultured microorganisms
    • DOI 10.1128/MMBR.68.4.669-685.2004
    • Handelsman J. (2004). Metagenomics: application of genomics to uncultured microorganisms. Microbiol Mol Biol Rev 68: 669-685 (Pubitemid 39628532)
    • (2004) Microbiology and Molecular Biology Reviews , vol.68 , Issue.4 , pp. 669-685
    • Handelsman, J.1
  • 24
    • 72649084530 scopus 로고    scopus 로고
    • Polymerase chain reaction primers miss half of rRNA microbial diversity
    • Hong SH, Bunge J, Leslin C, Jeon S, Epstein SS. (2009). Polymerase chain reaction primers miss half of rRNA microbial diversity. ISME J 3: 1365-1373
    • (2009) ISME J , vol.3 , pp. 1365-1373
    • Hong, S.H.1    Bunge, J.2    Leslin, C.3    Jeon, S.4    Epstein, S.S.5
  • 25
    • 0000060902 scopus 로고
    • Gas-exchange of legume nodules and the regulation of nitrogenase activity
    • Hunt S, Layzell DB. (1993). Gas-exchange of legume nodules and the regulation of nitrogenase activity. Annu Rev Plant Physiol Plant Mol Biol 44: 483-511
    • (1993) Annu Rev Plant Physiol Plant Mol Biol , vol.44 , pp. 483-511
    • Hunt, S.1    Layzell, D.B.2
  • 26
    • 33847702910 scopus 로고    scopus 로고
    • MEGAN analysis of metagenomic data
    • DOI 10.1101/gr.5969107
    • Huson DH, Auch AF, Qi J, Schuster SC. (2007). MEGAN analysis of metagenomic data. Genome Res 17: 377-386 (Pubitemid 46376747)
    • (2007) Genome Research , vol.17 , Issue.3 , pp. 377-386
    • Huson, D.H.1    Auch, A.F.2    Qi, J.3    Schuster, S.C.4
  • 27
    • 84855614028 scopus 로고    scopus 로고
    • Comparative analysis of bacterial communities in a potato field as determined by pyrosequencing
    • Inceoglu O, Abu Al-Soud W, Salles JF, Semenov AV, van Elsas JD. (2011). Comparative analysis of bacterial communities in a potato field as determined by pyrosequencing. PLoS One 6: 11
    • (2011) PLoS One , vol.6 , pp. 11
    • Inceoglu, O.1    Abu Al-Soud, W.2    Salles, J.F.3    Semenov, A.V.4    Van Elsas, J.D.5
  • 28
    • 33644952722 scopus 로고    scopus 로고
    • Identifying the dominant soil bacterial taxa in libraries of 16S rRNA and 16S rRNA genes
    • Janssen PH. (2006). Identifying the dominant soil bacterial taxa in libraries of 16S rRNA and 16S rRNA genes. Appl Environ Microbiol 72: 1719-1728
    • (2006) Appl Environ Microbiol , vol.72 , pp. 1719-1728
    • Janssen, P.H.1
  • 29
    • 77149153028 scopus 로고    scopus 로고
    • Methylophilaceae link methanol oxidation to denitrification in freshwater lake sediment as suggested by stable isotope probing and pure culture analysis
    • Kalyuhznaya MG, Martens-Habbena W, Wang TS, Hackett M, Stolyar SM, Stahl DA et al. (2009). Methylophilaceae link methanol oxidation to denitrification in freshwater lake sediment as suggested by stable isotope probing and pure culture analysis. Environ Microbiol Rep 1: 385-392
    • (2009) Environ Microbiol Rep , vol.1 , pp. 385-392
    • Kalyuhznaya, M.G.1    Martens-Habbena, W.2    Wang, T.S.3    Hackett, M.4    Stolyar, S.M.5    Stahl, D.A.6
  • 30
    • 84862590329 scopus 로고    scopus 로고
    • Metaproteogenomic analysis of microbial communities in the phyllosphere and rhizosphere of rice
    • Knief C, Delmotte N, Chaffron S, Stark M, Innerebner G, Wassmann R et al. (2012). Metaproteogenomic analysis of microbial communities in the phyllosphere and rhizosphere of rice. ISME J 6: 1378-1390
    • (2012) ISME J , vol.6 , pp. 1378-1390
    • Knief, C.1    Delmotte, N.2    Chaffron, S.3    Stark, M.4    Innerebner, G.5    Wassmann, R.6
  • 31
    • 33745803829 scopus 로고    scopus 로고
    • Structure and activity of bacterial community inhabiting rice roots and the rhizosphere
    • DOI 10.1111/j.1462-2920.2006.01028.x
    • Lu YH, Rosencrantz D, Liesack W, Conrad R. (2006). Structure and activity of bacterial community inhabiting rice roots and the rhizosphere. Environ Microbiol 8: 1351-1360 (Pubitemid 44025329)
    • (2006) Environmental Microbiology , vol.8 , Issue.8 , pp. 1351-1360
    • Lu, Y.1    Rosencrantz, D.2    Liesack, W.3    Conrad, R.4
  • 34
    • 33846043996 scopus 로고    scopus 로고
    • Isolation and characterization of hydrogen-oxidizing bacteria induced following exposure of soil to hydrogen gas and their impact on plant growth
    • DOI 10.1111/j.1462-2920.2006.01155.x
    • Maimaiti J, Zhang Y, Yang J, Cen YP, Layzell DB, Peoples M et al. (2007). Isolation and characterization of hydrogen-oxidizing bacteria induced following exposure of soil to hydrogen gas and their impact on plant growth. Environ Microbiol 9: 435-444 (Pubitemid 46072129)
    • (2007) Environmental Microbiology , vol.9 , Issue.2 , pp. 435-444
    • Maimaiti, J.1    Zhang, Y.2    Yang, J.3    Cen, Y.-P.4    Layzell, D.B.5    Peoples, M.6    Dong, Z.7
  • 35
    • 0002679958 scopus 로고
    • Avenacin antimicrobial substance isolated from avena sativa.1 Isolation antimicrobial activity
    • Maizel JV, Mitchell HK, Burkhardt HJ. (1964). Avenacin antimicrobial substance isolated from avena sativa.1 Isolation?antimicrobial activity. Biochemistry 3: 424-426
    • (1964) Biochemistry , vol.3 , pp. 424-426
    • Maizel, J.V.1    Mitchell, H.K.2    Burkhardt, H.J.3
  • 37
    • 79957595286 scopus 로고    scopus 로고
    • Deciphering the rhizosphere microbiome for disease-suppressive bacteria
    • Mendes R, Kruijt M, de Bruijn I, Dekkers E, van der Voort M, Schneider JHM et al. (2011). Deciphering the rhizosphere microbiome for disease-suppressive bacteria. Science 332: 1097-1100
    • (2011) Science , vol.332 , pp. 1097-1100
    • Mendes, R.1    Kruijt, M.2    De Bruijn, I.3    Dekkers, E.4    Van Der Voort, M.5    Jhm, S.6
  • 38
    • 0028251295 scopus 로고
    • An oat species lacking avenacin is susceptible to infection by Gaeumannomyces-Graminis var tritici
    • Osbourn AE, Clarke BR, Lunness P, Scott PR, Daniels MJ. (1994). An oat species lacking avenacin is susceptible to infection by Gaeumannomyces-Graminis var tritici. Physiol Mol Plant Pathol 45: 457-467
    • (1994) Physiol Mol Plant Pathol , vol.45 , pp. 457-467
    • Osbourn, A.E.1    Clarke, B.R.2    Lunness, P.3    Scott, P.R.4    Daniels, M.J.5
  • 39
    • 81855170246 scopus 로고    scopus 로고
    • Metatranscriptomic analysis of autonomously collected and preserved marine bacterioplankton
    • Ottesen EA, Marin R, Preston CM, Young CR, Ryan JP, Scholin CA et al. (2011). Metatranscriptomic analysis of autonomously collected and preserved marine bacterioplankton. ISME J 5: 1881-1895
    • (2011) ISME J , vol.5 , pp. 1881-1895
    • Ottesen, E.A.1    Marin, R.2    Preston, C.M.3    Young, C.R.4    Ryan, J.P.5    Scholin, C.A.6
  • 42
    • 77952088961 scopus 로고    scopus 로고
    • Biochemical cycling in the rhizosphere having an impact on global change
    • Philippot L, Hallin S, Borjesson G, Baggs EM. (2009). Biochemical cycling in the rhizosphere having an impact on global change. Plant Soil 321: 61-81
    • (2009) Plant Soil , vol.321 , pp. 61-81
    • Philippot, L.1    Hallin, S.2    Borjesson, G.3    Baggs, E.M.4
  • 43
    • 84865060813 scopus 로고    scopus 로고
    • PCR biases distort bacterial and archaeal community structure in pyrosequencing datasets
    • Pinto AJ, Raskin L. (2012). PCR biases distort bacterial and archaeal community structure in pyrosequencing datasets. PLoS One 7: 16
    • (2012) PLoS One , vol.7 , pp. 16
    • Pinto, A.J.1    Raskin, L.2
  • 44
    • 66649089244 scopus 로고    scopus 로고
    • Comparative day/night metatranscriptomic analysis of microbial communities in the North Pacific subtropical gyre
    • Poretsky RS, Hewson I, Sun SL, Allen AE, Zehr JP, Moran MA. (2009). Comparative day/night metatranscriptomic analysis of microbial communities in the North Pacific subtropical gyre. Environ Microbiol 11: 1358-1375
    • (2009) Environ Microbiol , vol.11 , pp. 1358-1375
    • Poretsky, R.S.1    Hewson, I.2    Sun, S.L.3    Allen, A.E.4    Zehr, J.P.5    Moran, M.A.6
  • 45
    • 37549027613 scopus 로고    scopus 로고
    • SILVA: A comprehensive online resource for quality checked and aligned ribosomal RNA sequence data compatible with ARB
    • Pruesse E, Quast C, Knittel K, Fuchs BM, Ludwig WG, Peplies J et al. (2007). SILVA: a comprehensive online resource for quality checked and aligned ribosomal RNA sequence data compatible with ARB. Nucleic Acids Res 35: 7188-7196
    • (2007) Nucleic Acids Res , vol.35 , pp. 7188-7196
    • Pruesse, E.1    Quast, C.2    Knittel, K.3    Fuchs, B.M.4    Ludwig, W.G.5    Peplies, J.6
  • 46
    • 80054726989 scopus 로고    scopus 로고
    • Adaptation of Rhizobium leguminosarum to pea, alfalfa and sugar beet rhizospheres investigated by comparative transcriptomics
    • Ramachandran VK, East AK, Ramakrishnan K, Downie JA, Poole PS. (2011). Adaptation of Rhizobium leguminosarum to pea, alfalfa and sugar beet rhizospheres investigated by comparative transcriptomics. Genome Biol 12: R106
    • (2011) Genome Biol , vol.12
    • Ramachandran, V.K.1    East, A.K.2    Ramakrishnan, K.3    Downie, J.A.4    Poole, P.S.5
  • 47
  • 49
    • 67549107261 scopus 로고    scopus 로고
    • Soil amoebae rapidly change bacterial community composition in the rhizosphere of arabidopsis thaliana
    • Rosenberg K, Bertaux J, Krome K, Hartmann A, Scheu S, Bonkowski M. (2009). Soil amoebae rapidly change bacterial community composition in the rhizosphere of arabidopsis thaliana. ISME J 3: 675-684
    • (2009) ISME J , vol.3 , pp. 675-684
    • Rosenberg, K.1    Bertaux, J.2    Krome, K.3    Hartmann, A.4    Scheu, S.5    Bonkowski, M.6
  • 51
    • 84858433066 scopus 로고    scopus 로고
    • Break-crop benefits to wheat in Western Australia-insights from over three decades of research
    • Seymour M, Kirkegaard JA, Peoples MB, White PF, French RJ. (2012). Break-crop benefits to wheat in Western Australia-insights from over three decades of research. Crop Past Sci 63: 1-16
    • (2012) Crop Past Sci , vol.63 , pp. 1-16
    • Seymour, M.1    Kirkegaard, J.A.2    Peoples, M.B.3    White, P.F.4    French, R.J.5
  • 52
    • 66149130975 scopus 로고    scopus 로고
    • Metatranscriptomics reveals unique microbial small RNAs in the ocean's water column
    • Shi YM, Tyson GW, DeLong EF. (2009). Metatranscriptomics reveals unique microbial small RNAs in the ocean?s water column. Nature 459: 266-U154
    • (2009) Nature , vol.459
    • Shi, Y.M.1    Tyson, G.W.2    Delong, E.F.3
  • 53
    • 79956287318 scopus 로고    scopus 로고
    • Integrated metatranscriptomic and metagenomic analyses of stratified microbial assemblages in the open ocean
    • Shi YM, Tyson GW, Eppley JM, DeLong EF. (2011). Integrated metatranscriptomic and metagenomic analyses of stratified microbial assemblages in the open ocean. ISME J 5: 999-1013
    • (2011) ISME J , vol.5 , pp. 999-1013
    • Shi, Y.M.1    Tyson, G.W.2    Eppley, J.M.3    Delong, E.F.4
  • 54
    • 77954086440 scopus 로고    scopus 로고
    • Development and quantitative analyses of a universal rRNAsubtraction protocol for microbial metatranscriptomics
    • Stewart FJ, Ottesen EA, DeLong EF. (2010). Development and quantitative analyses of a universal rRNAsubtraction protocol for microbial metatranscriptomics. ISME J 4: 896-907
    • (2010) ISME J , vol.4 , pp. 896-907
    • Stewart, F.J.1    Ottesen, E.A.2    Delong, E.F.3
  • 56
    • 77954834790 scopus 로고    scopus 로고
    • Bacterial diversity in rhizosphere soil from Antarctic vascular plants of Admiralty Bay, maritime Antarctica
    • Teixeira L, Peixoto RS, Cury JC, Sul WJ, Pellizari VH, Tiedje J et al. (2010). Bacterial diversity in rhizosphere soil from Antarctic vascular plants of Admiralty Bay, maritime Antarctica. ISME J 4: 989-1001
    • (2010) ISME J , vol.4 , pp. 989-1001
    • Teixeira, L.1    Peixoto, R.S.2    Cury, J.C.3    Sul, W.J.4    Pellizari, V.H.5    Tiedje, J.6
  • 58
    • 49649087440 scopus 로고    scopus 로고
    • Simultaneous assessment of soil microbial community structure and function through analysis of the meta-transcriptome
    • Urich T, Lanzen A, Qi J, Huson DH, Schleper C, Schuster SC. (2008). Simultaneous assessment of soil microbial community structure and function through analysis of the meta-transcriptome. PLoS One 3: e2527
    • (2008) PLoS One , vol.3
    • Urich, T.1    Lanzen, A.2    Qi, J.3    Huson, D.H.4    Schleper, C.5    Schuster, S.C.6
  • 59
    • 79953742137 scopus 로고    scopus 로고
    • Culturedependent and culture-independent assessment of bacteria in the apple phyllosphere
    • Yashiro E, Spear RN, McManus PS. (2011). Culturedependent and culture-independent assessment of bacteria in the apple phyllosphere. J Appl Microbiol 110: 1284-1296
    • (2011) J Appl Microbiol , vol.110 , pp. 1284-1296
    • Yashiro, E.1    Spear, R.N.2    McManus, P.S.3
  • 60
    • 80455168272 scopus 로고    scopus 로고
    • Duplex-specific nuclease efficiently removes rRNA for prokaryotic RNA-seq
    • Yi H, Cho YJ, Won S, Lee JE, Yu HJ, Kim S et al. (2011). Duplex-specific nuclease efficiently removes rRNA for prokaryotic RNA-seq. Nucleic Acids Res 39: 9
    • (2011) Nucleic Acids Res , vol.39 , pp. 9
    • Yi, H.1    Cho, Y.J.2    Won, S.3    Lee, J.E.4    Yu, H.J.5    Kim, S.6
  • 61
    • 33745094990 scopus 로고    scopus 로고
    • The genome of Rhizobium leguminosarum has recognizable core and accessory components
    • Young JPW, Crossman LC, Johnston AWB, thomson NR, Ghazoui ZF, Hull KH et al. (2006). the genome of Rhizobium leguminosarum has recognizable core and accessory components. Genome Biol 7: 20
    • (2006) Genome Biol , vol.7 , pp. 20
    • Jpw, Y.1    Crossman, L.C.2    Awb, J.3    Thomson, N.R.4    Ghazoui, Z.F.5    Hull, K.H.6
  • 62
    • 84864143923 scopus 로고    scopus 로고
    • Molecular characterization of root-associated fungal communities in relation to health status of Pisum sativum using barcoded pyrosequencing
    • Yu L, Nicolaisen M, Larsen J, Ravnskov S. (2012). Molecular characterization of root-associated fungal communities in relation to health status of Pisum sativum using barcoded pyrosequencing. Plant Soil 357: 395-405.
    • (2012) Plant Soil , vol.357 , pp. 395-405
    • Yu, L.1    Nicolaisen, M.2    Larsen, J.3    Ravnskov, S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.