Phospholipase A2 receptor staining in pediatric idiopathic membranous glomerulopathy

Pediatric Nephrology

Volumn 28, Issue 12, 2013, Pages 2307-2311

  Cossey, L Nicholas ^a   Walker, Patrick D ^a,b   Larsen, Chris P ^a,b  

^a Nephropath   (United States)

^b UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

Author keywords

IgG4; Membranous glomerulonephritis; Membranous glomerulopathy; Membranous nephropathy; Phospholipase A2 receptor; PLA2R

Indexed keywords

BOVINE SERUM ALBUMIN; COMPLEMENT COMPONENT C1Q; COMPLEMENT COMPONENT C3; IMMUNOGLOBULIN G; PHOSPHOLIPASE A2 RECEPTOR;

ADOLESCENT; ARTICLE; CHILD; CLINICAL ARTICLE; CONFIDENCE INTERVAL; CONTROLLED STUDY; FEMALE; FOLLOW UP; HUMAN; HUMAN TISSUE; IDIOPATHIC DISEASE; IMMUNOELECTRON MICROSCOPY; IMMUNOFLUORESCENCE MICROSCOPY; KIDNEY BIOPSY; MALE; MEMBRANOUS GLOMERULONEPHRITIS; MESANGIUM CELL; PRIORITY JOURNAL; SCHOOL CHILD; SENSITIVITY AND SPECIFICITY; SUBENDOTHELIUM;

ADOLESCENT; AGE FACTORS; BIOLOGICAL MARKERS; BIOPSY; CHILD; CHILD, PRESCHOOL; COMPLEMENT C1Q; COMPLEMENT C3; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; GLOMERULONEPHRITIS, MEMBRANOUS; HUMANS; IMMUNOGLOBULIN G; KIDNEY; MALE; PREDICTIVE VALUE OF TESTS; PROGNOSIS; RECEPTORS, PHOSPHOLIPASE A2; RISK FACTORS; TIME FACTORS;

EID: 84888198467     PISSN: 0931041X     EISSN: 1432198X     Source Type: Journal    
DOI: 10.1007/s00467-013-2574-9     Document Type: Article

References (24)

1. Bell ET (1950) Renal diseases. Lea & Febiger, Philadelphia
2. Jones DB (1957) Nephrotic glomerulonephritis. Am J Pathol 33:313-329
3. Movat HZ, McGregor DD (1959) The fine structure of the glomerulus in membranous glomerulonephritis (lipoid nephrosis) in adults. Am J Clin Pathol 32:100-127
4. Mellors RC, Ortega LG, Holman HR (1957) Role of gammaglobulins in pathogenesis of renal lesions in systemic lupus erythematosus and chronic membranous glomerulonephriris, with an observation of the lupus erythematosus cell reaction. J Exp Med 1065:191-202
5. Heymann W, Hackel DB, Harwood S, Wilson SGF, Hunter JL (2000) Production of nephrotic syndrome in rats by Freund's adjuvants and rat kidney suspensions. J Am Soc Nephrol 10:183-188
6. Makker SP, Singh AK (1984) Characterization of the antigen (gp600) of heymann nephritis. Lab Investig 50:287-293
7. Beck LH, Bonegio RG, Lambeau G, Beck DM, Powell DW, Cummins TD, Klein JB, Salant DJ (2009) M-type phospholipase A2 receptor as target antigen in idiopathic membranous nephropathy. N Engl J Med 361:11-21
8. Qin W, Beck LH Jr, Zeng C, Chen Z, Li S, Zuo K, Salant DJ, Liu Z (2011) Anti-phospholipase A2 receptor antibody in membranous nephropathy. J Am Soc Nephrol 22:1137-1143
9. Debiec H, Martin L, Jouanneau C, Dautin G, Mesnard L, Rondeau E, Mousson C, Ronco P (2011) Autoantibodies specific for the phospholipase A2 receptor in recurrent and De Novo membranous nephropathy. Am J Transplant 11:2144-2152
10. Larsen CP, Messias NC, Silva FG, Messias E, Walker PD (2013) Determination of primary versus secondary membranous glomerulopathy utilizing phospholipase A2 receptor (PLA2R1) staining in renal biopsies. Mod Pathol 26:709-715
11. Churg J, Habib R, White RH (1970) Pathology of the nephrotic syndrome in children: a report for the International Study of Kidney Disease in Children. Lancet 760:1299-1302
12. A report for the International Study of Kidney Disease in Children (1978) Nephrotic syndrome in children: prediction of histopathology from clinical and laboratory characteristics at time of diagnosis. Kidney Int 13:159-165
13. Markowitz GS (2001) Membranous glomerulopathy: emphasis on secondary forms and disease variants. Adv Anat Pathol 8:119-125
14. Beck LH Jr (2012) Childhood membranous nephropathy and dietary antigens. Am J Kidney Dis 59:174-176
15. Debiec H, Lefeu F, Kemper MJ, Niaudet P, Deschênes G, Remuzzi G, Ulinski T, Ronco P (2011) Early-childhood membranous nephropathy due to cationic bovine serum albumin. N Engl J Med 364:2101-2110
16. Debiec H, Guigonis V, Mougenot B, Decobert F, Haymann J, Bensman A, Deschenes G, Ronco PM (2002) Antenatal membranous glomerulonephritis due to anti-neutral endopeptidase antibodies. N Engl J Med 346:2053-2060
17. Walker PD, Cavallo T, Bonsib SM (2004) Practice guidelines for the renal biopsy. Mod Pathol 17:1555-1563
18. Walker PD (2009) The renal biopsy. Arch Pathol Lab Med 133:181-188
19. Ehrenreich T, Churg J (1968) Pathology of membranous nephropathy. Pathol Annu 2:145-186
20. Jennette JC, Iskandar SS, Dalldorf FG (1983) Pathologic differentiation between lupus and nonlupus membranous glomerulopathy. Kidney Int 24:377-385
21. Debiec H, Ronco P (2011) PLA2R autoantibodies and PLA2R glomerular deposits in membranous nephropathy. N Engl J Med 364:689-690
22. Menon S, Valentini R (2010) Membranous nephropathy in children: clinical presentation and therapeutic approach. Pediatr Nephrol 25:1419-1428
23. Waldman M, Austin HA III (2009) Controversies in the treatment of idiopathic membranous nephropathy. Nat Rev Nephrol 5:469-479
24. Valentini RP, Mattoo TK, Kapur G, Imam A (2009) Membranous glomerulonephritis: treatment response and outcome in children. Pediatr Nephrol 24:301-308