Comparison between human and porcine thromboelastograph parameters in response to ex-vivo changes to platelets, plasma, and red blood cells

Blood Coagulation and Fibrinolysis

Volumn 24, Issue 8, 2013, Pages 818-829

  Sondeen, Jill L ^a   De Guzman, Rodolfo ^a   Amy Polykratis, Irene ^a   Dale Prince, Malcolm ^a   Hernandez, Orlando ^a   Cap, Andrew P ^a   Dubick, Michael A ^a  

^a US ARMY INSTITUTE OF SURGICAL RESEARCH   (United States)

Author keywords

blood platelets; fibrinogen; hematocrit; humans; pigs; thrombelastography

Indexed keywords

CITRATE SODIUM; FIBRINOGEN; RINGER LACTATE SOLUTION;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BLOOD CLOTTING; BLOOD SAMPLING; CATHETER; CENTRIFUGATION; COMPARATIVE STUDY; CRYOPRECIPITATE; DILUTION; EX VIVO STUDY; FEMALE; HEMATOCRIT; HUMAN; HUMAN CELL; MALE; NONHUMAN; NORMAL HUMAN; PRIORITY JOURNAL; SENSITIVITY ANALYSIS; SWINE; THROMBOCYTE COUNT; THROMBOCYTE POOR PLASMA; THROMBOCYTE RICH PLASMA; THROMBOELASTOGRAPHY;

ADULT; ANIMALS; ANTICOAGULANTS; BLOOD COAGULATION; BLOOD PLATELETS; CELLS, CULTURED; CITRATES; ERYTHROCYTE COUNT; ERYTHROCYTES; FEMALE; FIBRINOGEN; HEMATOCRIT; HUMANS; ISOTONIC SOLUTIONS; MALE; PLATELET COUNT; PLATELET-RICH PLASMA; SWINE; THROMBELASTOGRAPHY;

EID: 84888136563     PISSN: 09575235     EISSN: 14735733     Source Type: Journal    
DOI: 10.1097/MBC.0b013e3283646600     Document Type: Article

References (26)

1. Allen SR, Kashuk JL. Unanswered questions in the use of blood component therapy in trauma. Scand J Trauma Resusc Emerg Med 2011; 19:1-5.
2. Holcomb JB, Jenkins D, Rhee P, Johannigman J, Mahoney P, Mehta S, et al. Damage control resuscitation: directly addressing the early coagulopathy of trauma. J Trauma 2007; 62:307-310.
3. Morrison CA, Carrick MM, Norman MA, Scott BG, Welsh FJ, Tsai P, et al. Hypotensive resuscitation strategy reduces transfusion requirements and severe postoperative coagulopathy in trauma patients with hemorrhagic shock: preliminary results of a randomized controlled trial. J Trauma 2011; 70:652-663.
4. Borgman MA, Spinella PC, Perkins JG, Grathwohl KW, Repine T, Beekley AC, et al. The ratio of blood products transfused affects mortality in patients receiving massive transfusions at a combat support hospital. J Trauma 2007; 63:805-813.
5. Peiniger S, Nienaber U, Lefering R, Braun M, Wafaisade A, Wutzler S, et al. Balanced massive transfusion ratios in multiple injury patients with traumatic brain injury. Crit Care 2011; 15:R68.
6. Nascimento B, Rizoli S, Rubenfeld G, Lin Y, Callum J, Tien HC. Design and preliminary results of a pilot randomized controlled trial on a 1:1:1 transfusion strategy: the trauma formula-driven versus laboratory-guided study. J Trauma 2011; 71 (5 Suppl 1):S418-S426.
7. Wade CE, Dubick MA, Blackbourne LH, Holcomb JB. It is time to assess the utility of thrombelastography in the administration of blood products to the patient with traumatic injuries. J Trauma 2009; 66:1258.
8. Wegner J, Popovsky MA. Clinical utility of thromboelastography: one size does not fit all. Semin Thromb Hemost 2010; 36:699-706.
9. Hoffman M, Monroe DM 3rd. A cell-based model of hemostasis. Thromb Haemost 2001; 85:958-965.
10. Johansson PI, Svendsen MS, Salado J, Bochsen L, Kristensen AT. Investigation of the thrombin-generating capacity, evaluated by thrombogram, and clot formation evaluated by thrombelastography of platelets stored in the blood bank for up to 7 days. Vox Sang 2008; 94:113-118.
11. Haemoscope. Thromboelastography (TEG) hemostasis analyzer user manual. Niles, IL: Haemoscope; 2004.
12. Kashuk JL, Moore EE, Sawyer M, Le T, Johnson J, Biffl WL, et al. Postinjury coagulopathy management: goal directed resuscitation via POC thrombelastography. Ann Surg 2010; 251:604-614.
13. Stahel PF, Moore EE, Schreier SL, Flierl MA, Kashuk JL. Transfusion strategies in postinjury coagulopathy. Curr Opin Anaesthesiol 2009; 22:289-298.
14. Theusinger OM, Spahn DR, Ganter MT. Transfusion in trauma: why and how should we change our current practice? Curr Opin Anaesthesiol 2009; 22:305-312.
15. Walsh M, Thomas SG, Howard JC, Evans E, Guyer K, Medvecz A, et al. Blood component therapy in trauma guided with the utilization of the perfusionist and thromboelastography. J Extra Corpor Technol 2011; 43:162-167.
16. Nielsen VG, Cohen BM, Cohen E. Effects of coagulation factor deficiency on plasma coagulation kinetics determined via thrombelastography: critical roles of fibrinogen and factors II, VII, X and XII. Acta Anaesthesiol Scand 2005; 49:222-231.
17. Bochsen L, Johansson PI, Kristensen AT, Daugaard G, Ostrowski SR. The influence of platelets, plasma and red blood cells on functional haemostatic assays. Blood Coagul Fibrinolysis 2011; 22:167-175.
18. Larsen OH, Ingerslev J, Sorensen B. Whole blood laboratory model of thrombocytopenia for use in evaluation of hemostatic interventions. Ann Hematol 2007; 86:217-221.
19. Darlington DN, Delgado AV, Kheirabadi BS, Fedyk CG, Scherer MR, Pusateri AE, et al. Effect of hemodilution on coagulation and recombinant factor VIIa efficacy in human blood in vitro. J Trauma 2011; 71:1152-1163.
20. Sondeen JL, Prince MD, Kheirabadi BS, Wade CE, Polykratis IA, de Guzman R, et al. Initial resuscitation with plasma and other blood components reduced bleeding compared to hetastarch in anesthetized swine with uncontrolled splenic hemorrhage. Transfusion 2011; 51:779-792.
21. Olsen AK, Marckmann P, Bladbjerg EM. The pig as a model in blood coagulation and fibrinolysis research. Scand J Lab Anim Sci 1999; 26:214-224.
22. Bolliger D, Seeberger MD, Tanaka KA. Principles and practice of thromboelastography in clinical coagulation management and transfusion practice. Transfus Med Rev 2012; 26:1-13.
23. Blasi A, Beltran J, Pereira A, Martinez-Palli G, Torrents A, Balust J, et al. An assessment of thromboelastometry to monitor blood coagulation and guide transfusion support in liver transplantation. Transfusion 2012; 52:1989-1998.
24. Rugeri L, Levrat A, David JS, Delecroix E, Floccard B, Gros A, et al. Diagnosis of early coagulation abnormalities in trauma patients by rotation thrombelastography. J Thromb Haemost 2007; 5:289-295.
25. Roeloffzen WW, Kluin-Nelemans HC, Bosman L, de Wolf JT. Effects of red blood cells on hemostasis. Transfusion 2010; 50:1536-1544.
26. Brown LM, Call MS, Margaret Knudson M, Cohen MJ, Holcomb JB, Wade CE, et al. A normal platelet count may not be enough: the impact of admission platelet count on mortality and transfusion in severely injured trauma patients. J Trauma 2011; 71 (2 Suppl 3):S337-S342.