Influence of time delay on the estimated lung shunt fraction on 99mTC-labeled maa scintigraphy for 90Y microsphere treatment planning

Clinical Nuclear Medicine

Volumn 38, Issue 12, 2013, Pages 940-942

  De Gersem, Ruth ^a   Maleux, Geert ^a   Vanbilloen, Hubert ^a   Baete, Kristof ^a   Verslype, Chris ^a   Haustermans, Karin ^a   Verbruggen, Alfons ^a   Van Cutsem, Eric ^a   Deroose, Christophe Michel ^a  

^a UNIVERSITY HOSPITALS LEUVEN   (Belgium)

Author keywords

injection scan interval; lung shunt; MAA; selective internal radiation therapy

Indexed keywords

MACROSALB TC 99M; MICROSPHERE; YTTRIUM 90;

ADULT; AGED; ARTICLE; BODY SURFACE; CASE REPORT; COLORECTAL LIVER METASTASIS; DRUG DEGRADATION; FEMALE; GAMMA CAMERA; HEPATIC ARTERY; HUMAN; ISOTOPE LABELING; MALE; PULMONARY SHUNT; RADIATION DOSE REDUCTION; RADIOTHERAPY; SELECTIVE INTERNAL RADIATION THERAPY; SIMULATION; TIME; TREATMENT PLANNING; URINARY TRACT; WHOLE BODY SCANNER; WHOLE BODY SCINTISCANNING;

AGED; FEMALE; HUMANS; INJECTIONS; LUNG; MALE; MICROSPHERES; MIDDLE AGED; RADIOTHERAPY PLANNING, COMPUTER-ASSISTED; TECHNETIUM TC 99M AGGREGATED ALBUMIN; TIME FACTORS; VENTILATION-PERFUSION RATIO; YTTRIUM RADIOISOTOPES;

EID: 84888134178     PISSN: 03639762     EISSN: 15360229     Source Type: Journal    
DOI: 10.1097/RLU.0000000000000241     Document Type: Article

References (10)

1. Ahmadzadehfar H, Biersack HJ, Ezziddin S. Radioembolization of liver tumors with yttrium-90 microspheres. Semin Nucl Med. 2010;40:105-121.
2. Ackerman NB, Lien WM, Kondi ES, et al. The blood supply of experimental liver metastases. I. The distribution of hepatic artery and portal vein blood to ''small'' and ''large'' tumors. Surgery. 1969;66:1067-1072.
3. Campbell AM, Bailey IH, Burton MA. Analysis of the distribution of intraarterial microspheres in human liver following hepatic yttrium-90 microsphere therapy. Phys Med Biol. 2000;45:1023-1033.
4. Flamen P, Vanderlinden B, Delatte P, et al. Multimodality imaging can predict the metabolic response of unresectable colorectal liver metastases to radioembolization therapy with yttrium-90 labeled resin microspheres. Phys Med Biol. 2008;53:6591-6603.
5. Kennedy A, Nag S, Salem R, et al. Recommendations for radioembolization of hepatic malignancies using yttrium-90 microsphere brachytherapy: a consensus panel report from the radioembolization brachytherapy oncology consortium. Int J Radiat Oncol Biol Phys. 2007;68:13-23.
6. Lenoir L, Edeline J, Rolland Y, et al. Usefulness and pitfalls of MAA SPECT/CT in identifying digestive extrahepatic uptake when planning liver radioembolization. Eur J Nucl Med Mol Imaging. 2012;39:872-880.
7. Garin E, Lenoir L, Rolland Y, et al. Effectiveness of quantitative MAA SPECT/CT for the definition of vascularized hepatic volume and dosimetric approach: phantom validation and clinical preliminary results in patients with complex hepatic vascularization treated with yttrium-90-labeled microspheres. Nucl Med Commun. 2011;32:1245-1255.
8. Mariani G, Bruselli L, Kuwert T, et al. A review on the clinical uses of SPECT/CT. Eur J Nucl Med Mol Imaging. 2010;37:1959-1985.
9. Lambert B, Mertens J, Sturm EJ, et al. 99mTc-labelled macroaggregated albumin (MAA) scintigraphy for planning treatment with 90Y microspheres. Eur J Nucl Med Mol Imaging. 2010;37:2328-2333.
10. Hendlisz A, Van den Eynde M, Peeters M, et al. Phase III trial comparing protracted intravenous fluorouracil infusion alone or with yttrium-90 resin microspheres radioembolization for liver-limited metastatic colorectal cancer refractory to standard chemotherapy. J Clin Oncol. 2010;28:3687-3694.