Usefulness and pitfalls of MAA SPECT/CT in identifying digestive extrahepatic uptake when planning liver radioembolization

European Journal of Nuclear Medicine and Molecular Imaging

Volumn 39, Issue 5, 2012, Pages 872-880

  Lenoir, Laurence ^a,b,c   Edeline, Julien ^a,b   Rolland, Yann ^a   Pracht, Marc ^a   Raoul, Jean Luc ^d   Ardisson, Valérie ^a   Bourguet, Patrick ^a,b   Clément, Bruno ^c   Boucher, Eveline ^a,c   Garin, Etienne ^a,b,c  

^a Department of Nuclear Medicine   (France)

^b UNIVERSITÉ DE RENNES 1   (France)

^c INSERM   (France)

^d INSTITUT PAOLI CALMETTES   (France)

Author keywords

MAA; Radioembolization; SPECT CT

Indexed keywords

MACROSALB TC 99M;

ARTICLE; ARTIFICIAL EMBOLISM; COIL EMBOLIZATION; COMPUTER ASSISTED TOMOGRAPHY; DIAGNOSTIC VALUE; DUODENUM; FEMALE; FOLLOW UP; GALLBLADDER; HEPATIC ARTERY; HUMAN; LIVER RADIOEMBOLIZATION; LIVER TUMOR; MAJOR CLINICAL STUDY; MALE; PORTAL VEIN THROMBOSIS; RETROSPECTIVE STUDY; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; TREATMENT PLANNING;

AGED; BIOLOGICAL TRANSPORT; DIGESTIVE SYSTEM; EMBOLIZATION, THERAPEUTIC; FALSE POSITIVE REACTIONS; FEMALE; HUMANS; LIVER NEOPLASMS; MALE; POSITRON-EMISSION TOMOGRAPHY AND COMPUTED TOMOGRAPHY; RADIOTHERAPY PLANNING, COMPUTER-ASSISTED; RETROSPECTIVE STUDIES; SULFHYDRYL COMPOUNDS; TECHNETIUM TC 99M AGGREGATED ALBUMIN; ULCER;

EID: 84862569875     PISSN: 16197070     EISSN: 16197089     Source Type: Journal    
DOI: 10.1007/s00259-011-2033-4     Document Type: Article

References (21)

1. Salem R, Lewandowski RJ, Mulcahy MF, Riaz A, Ryu RK, Ibrahim S, et al. Radioembolization for hepatocellular carcinoma using yttrium-90 microspheres: a comprehensive report of longterm outcomes. Gastroenterology 2010;138(1):52-64.
2. Hilgard P, Hamami M, Fouly AE, Scherag A, Müller S, Ertle J, et al. Radioembolization with yttrium-90 glass microspheres in hepatocellular carcinoma: European experience on safety and longterm survival. Hepatology 2010;52(5):1741-9.
3. Sangro B, Carpanese L, Cianni R, Golfieri R, Gasparini D, Ezziddin S, on behalf of the European Network on Radioembolization with Yttrium-90 Resin Microspheres (ENRY), et al. Survival after yttrium-90 resin microsphere radioembolization of hepatocellular carcinoma across Barcelona clinic liver cancer stages: a European evaluation. Hepatology 2011;54:868-78. doi:10.1002/hep.24451[Epub ahead of print].
4. Sato KT, Lewandowski RJ, Mulcahy MF, Atassi B, Ryu RK, Gates V, et al. Unresectable chemorefractory liver metastases: radioembolization with 90Y microspheres-safety, efficacy, and survival. Radiology 2008;247(2):507-15.
5. Hendlisz A, Van den Eynde M, Peeters M, Maleux G, Lambert B, Vannoote J, et al. Phase III trial comparing protracted intravenous fluorouracil infusion alone or with yttrium-90 resin microspheres radioembolization for liver-limited metastatic colorectal cancer refractory to standard chemotherapy. J Clin Oncol 2010;28(23):3687-94.
6. Hamami ME, Poeppel TD, Müller S, Heusner T, Bockisch A, Hilgard P, et al. SPECT/CT with 99mTc-MAA in radioembolization with 90Y microspheres in patients with hepatocellular cancer. J Nucl Med 2009;50(5):688-92.
7. Ahmadzadehfar H, Sabet A, Biermann K, Muckle M, Brockmann H, Kuhl C, et al. The significance of 99mTc-MAA SPECT/CT liver perfusion imaging in treatment planning for 90Y-microsphere selective internal radiation treatment. J Nucl Med 2010;51(8): 1206-12.
8. Denecke T, Rühl R, Hildebrandt B, Stelter L, Grieser C, Stiepani H, et al. Planning transarterial radioembolization of colorectal liver metastases with yttrium 90 microspheres: evaluation of a sequential diagnostic approach using radiologic and nuclear medicine imaging techniques. Eur Radiol 2008;18(5):892-902.
9. Dudeck O, Wilhelmsen S, Ulrich G, Löwenthal D, Pech M, Amthauer H, et al. (2011) Effectiveness of repeat angiographic assessment in patients designated for radioembolization using yttrium-90 microspheres with initial extrahepatic accumulation of technetium-99m macroaggregated albumin: a single center's experience. Cardiovasc Intervent Radiol [Epub ahead of print].
10. Garin E, Rolland Y, Boucher E, Ardisson V, Laffont S, Boudjema K, et al. First experience of hepatic radioembolization using microspheres labelled with yttrium-90 (TheraSphere®): practical aspects concerning its implementation. Eur J Nucl Med Mol Imaging 2010;37:453-61.
11. Naymagon S,Warner RRP, Patel K, Harpaz N, Machac J,Weintraub JL, et al. Gastroduodenal ulceration associated with radioembolization for the treatment of hepatic tumors: an institutional experience and review of the literature. Dig Dis Sci 2010;55:2450-8.
12. Dancey JE, Shepherd FA, Paul K, Sniderman KW, Houle S, Gabrys J, et al. Treatment of nonresectable hepatocellular carcinoma with intrahepatic 90Y-microspheres. J Nucl Med 2000;41:1673-81.
13. Stubbs RS, Cannan RJ, Mitchell AW. Selective internal radiation therapy with 90yttrium microspheres for extensive colorectal liver metastases. J Gastrointest Surg 2001;5(3):294-302.
14. Lim L, Gibbs P, Yip D, Shapiro JD, Dowling R, Smith D, et al. A prospective evaluation of treatment with Selective Internal Radiation Therapy (SIR-spheres) in patients with unresectable liver metastases from colorectal cancer previously treated with 5-FU based chemotherapy. BMC Cancer 2005;5:132.
15. Kennedy AS, McNeillie P, Dezarn WA, Nutting C, Sangro B, Wertman D, et al. Treatment parameters and outcome in 680 treatments of internal radiation with resin 90Y-microspheres for unresectable hepatic tumors. Int J Radiat Oncol Biol Phys 2009;74 (5):1494-500.
16. Konda A, Savin MA, Cappell MS, Duffy MC. Radiation microsphere-induced GI ulcers after selective internal radiation therapy for hepatic tumors: an underrecognized clinical entity. Gastrointest Endosc 2009;70(3):561-7.
17. Sabet A, Ahmadzadehfar H, Muckle M, Haslerud T, Wilhelm K, Biersack HJ, et al. Significance of oral administration of sodium perchlorate in planning liver-directed radioembolization. J Nucl Med 2011;52(7):1063-7.
18. Ahmadzadehfar H, Möhlenbruch M, Sabet A, Meyer C, Muckle M, Haslerud T, et al. Is prophylactic embolization of the hepatic falciform artery needed before radioembolization in patients with 99mTc-MAA accumulation in the anterior abdominal wall? Eur J Nucl Med Mol Imaging 2011;38(8):1477-84.
19. Carr BI. Hepatic arterial 90Yttrium glassmicrospheres (Therasphere) for unresectable hepatocellular carcinoma: interim safety and survival data on 65 patients. Liver Transpl 2004;10(2 Suppl 1):S107-10.
20. Kennedy AS, McNeillie P, Dezarn WA, Nutting C, Sangro B, Wertman D, et al. Treatment parameters and outcome in 680 treatments of internal radiation with resin 90Y-microspheres for unresectable hepatic tumors. Int J Radiat Oncol Biol Phys 2009;74 (5):1494-500.
21. Vogel WV, van Dalen JA, Wiering B, Huisman H, Corstens FH, Ruers TJ, et al. Evaluation of image registration in PET/CT of the liver and recommendations for optimized imaging. J Nucl Med 2007;48(6):910-9.