Randomized clinical trial evaluating transdermal ibuprofen for moderate to severe knee osteoarthritis

Pain Physician

Volumn 16, Issue 6, 2013, Pages

  Varadi, Gyula ^a   Zhu, Zhen ^a   Blättler, Thomas ^b   Hösle, Manfred ^b   Loher, Alfons ^b   Pokorny, Rolf ^c   Frey, Diana ^d   Carter, Stephen G ^a  

^a Biochemics Inc   (United States)

^b Covance Clinical Research Unit AG ^*

^c Rheumaklinik und Institut fur Physikalische Medizin ^*  (Switzerland)

^d UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

Ibuprofen; Knee osteoarthritis; Transdermal treatment; VALE ibuprofen; Visual Analog Scale; WOMAC score

Indexed keywords

IBUPROFEN; PLACEBO; UNCLASSIFIED DRUG; VALE;

ABSENCE OF SIDE EFFECTS; ADULT; ARTICLE; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE SEVERITY; DOUBLE BLIND PROCEDURE; DRUG BLOOD LEVEL; DRUG DISTRIBUTION; DRUG EFFICACY; DRUG SAFETY; DRUG TISSUE LEVEL; DRUG TOLERABILITY; FEMALE; FUNCTIONAL ASSESSMENT; FUNCTIONAL STATUS; HUMAN; KNEE OSTEOARTHRITIS; KNEE PAIN; MAJOR CLINICAL STUDY; MALE; MAXIMUM PLASMA CONCENTRATION; MOTION; MULTICENTER STUDY; PATIENT SATISFACTION; PHASE 1 CLINICAL TRIAL; PHASE 2 CLINICAL TRIAL; RANDOMIZED CONTROLLED TRIAL; RASH; RIGIDITY; SINGLE DRUG DOSE; TISSUE DISTRIBUTION; TREND STUDY; VISUAL ANALOG SCALE; WEIGHT BEARING; WESTERN ONTARIO AND MCMASTER UNIVERSITIES OSTEOARTHRITIS INDEX;

ADMINISTRATION, CUTANEOUS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; DOUBLE-BLIND METHOD; FEMALE; HUMANS; IBUPROFEN; MALE; MIDDLE AGED; OSTEOARTHRITIS, KNEE; PAIN MEASUREMENT;

EID: 84888087481     PISSN: 15333159     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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