Cerebral blood flow response to acute hypoxic hypoxia

NMR in Biomedicine

Volumn 26, Issue 12, 2013, Pages 1844-1852

  Harris, Ashley D ^a   Murphy, Kevin ^a   Diaz, Claris M ^a   Saxena, Neeraj ^b   Hall, Judith E ^b   Liu, Thomas T ^c   Wise, Richard G ^a  

^a CARDIFF UNIVERSITY   (United Kingdom)

^b CARDIFF UNIVERSITY   (United Kingdom)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Arterial spin labelling (ASL); Blood oxygenation; Cerebral blood flow (CBF); Cerebral perfusion; Hypoxia; R2; Temporal dynamics

Indexed keywords

ARTERIAL SPIN LABELLING; BLOOD OXYGENATION; CEREBRAL BLOOD FLOW; CEREBRAL PERFUSION; HYPOXIA; R2; TEMPORAL DYNAMICS;

BLOOD; BRAIN; OXYGENATION;

RATE CONSTANTS;

ACUTE HYPOXIC HYPOXIA; ADULT; ARTICLE; BLOOD OXYGENATION; BRAIN BLOOD FLOW; BRAIN HYPOXIA; BRAIN PERFUSION; BRAIN REGION; FEMALE; GRAY MATTER; HUMAN; HUMAN EXPERIMENT; MALE; NORMAL HUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL;

ARTERIAL SPIN LABELLING (ASL); BLOOD OXYGENATION; CEREBRAL BLOOD FLOW (CBF); CEREBRAL PERFUSION; HYPOXIA; R2*; TEMPORAL DYNAMICS;

ACUTE DISEASE; ADULT; ANOXIA; CEREBROVASCULAR CIRCULATION; FEMALE; HUMANS; MALE; MODELS, BIOLOGICAL;

EID: 84888042677     PISSN: 09523480     EISSN: 10991492     Source Type: Journal    
DOI: 10.1002/nbm.3026     Document Type: Article

References (31)

1. Brugniaux JV, Hodges AN, Hanly PJ, Poulin MJ. Cerebrovascular responses to altitude. Respir. Physiol. Neurobiol. 2007; 158(2-3): 212-223.
2. Buck A, Schirlo C, Jasinksy V, Weber B, Burger C, von Schulthess GK, Koller EA, Pavlicek V. Changes of cerebral blood flow during short-term exposure to normobaric hypoxia. J. Cereb. Blood Flow Metab. 1998; 18(8): 906-910.
3. Wilson MH, Edsell ME, Davagnanam I, Hirani SP, Martin DS, Levett DZ, Thornton JS, Golay X, Strycharczuk L, Newman SP, Montgomery HE, Grocott MP, Imray CH. Cerebral artery dilatation maintains cerebral oxygenation at extreme altitude and in acute hypoxia-an ultrasound and MRI study. J. Cereb. Blood Flow Metab. 2011; 31(10): 2019-2029.
4. Kety SS, Schmidt CF. The determination of cerebral blood flow in man by the use of nitrous oxide in low concentrations. Am. J. Physiol. 1945; 143(1): 53-66.
5. Kety SS, Schmidt CF. The effects of altered arterial tensions of carbon dioxide and oxygen on cerebral blood flow and cerebral oxygen consumption of normal young men. J. Clin. Invest. 1948; 27(4): 484-492.
6. Battisti-Charbonney A, Fisher JA, Duffin J. Respiratory, cerebrovascular and cardiovascular responses to isocapnic hypoxia. Respir. Physiol. Neurobiol. 2011; 179(2-3): 259-268.
7. Willie CK, Macleod DB, Shaw AD, Smith KJ, Tzeng YC, Eves ND, Ikeda K, Graham J, Lewis NC, Day TA, Ainslie PN. Regional brain blood flow in man during acute changes in arterial blood gases. J. Physiol. 2012; 590(Pt 14): 3261-3275.
8. 2 in humans. J. Appl. Physiol. 1996; 81(3): 1084-1095.
9. Mintun MA, Lundstrom BN, Snyder AZ, Vlassenko AG, Shulman GL, Raichle ME. Blood flow and oxygen delivery to human brain during functional activity: theoretical modeling and experimental data. Proc. Natl. Acad. Sci. U. S. A. 2001; 98(12): 6859-6864.
10. Pagani M, Salmaso D, Sidiras GG, Jonsson C, Jacobsson H, Larsson SA, Lind F. Impact of acute hypobaric hypoxia on blood flow distribution in brain. Acta Physiol. (Oxford) 2011; 202(2): 203-209.
11. Binks AP, Cunningham VJ, Adams L, Banzett RB. Gray matter blood flow change is unevenly distributed during moderate isocapnic hypoxia in humans. J. Appl. Physiol. 2008; 104(1): 212-217.
12. Noth U, Kotajima F, Deichmann R, Turner R, Corfield DR. Mapping of the cerebral vascular response to hypoxia and hypercapnia using quantitative perfusion MRI at 3 T. NMR Biomed. 2008; 21(5): 464-472.
13. Dyer EA, Hopkins SR, Perthen JE, Buxton RB, Dubowitz DJ. Regional cerebral blood flow during acute hypoxia in individuals susceptible to acute mountain sickness. Respir. Physiol. Neurobiol. 2008; 160(3): 267-276.
14. Rostrup E, Larsson HBW, Toft PB, Garde K, Henriksen O. Signal changes in gradient echo images of human brain induced by hypo- and hyperoxia. NMR Biomed. 1995; 8(1): 41-47.
15. Wong EC, Buxton RB, Frank LR. Quantitative imaging of perfusion using a single subtraction (QUIPSS and QUIPSS II). Magn. Reson. Med. 1998; 39(5): 702-708.
16. Liu TT, Wong EC. A signal processing model for arterial spin labeling functional MRI. Neuroimage 2005; 24(1): 207-215.
17. Liau J, Perthen JE, Liu TT. Caffeine reduces the activation extent and contrast-to-noise ratio of the functional cerebral blood flow response but not the BOLD response. Neuroimage 2008; 42(1): 296-305.
18. Buxton RB, Frank LR, Wong EC, Siewert B, Warach S, Edelman RR. A general kinetic model for quantitative perfusion imaging with arterial spin labeling. Magn. Reson. Med. 1998; 40(3): 383-396.
19. Wegener S, Wu WC, Perthen JE, Wong EC. Quantification of rodent cerebral blood flow (CBF) in normal and high flow states using pulsed arterial spin labeling magnetic resonance imaging. J. Magn. Reson. Imaging 2007; 26(4): 855-862.
20. St Lawrence KS, Wang J. Effects of the apparent transverse relaxation time on cerebral blood flow measurements obtained by arterial spin labeling. Magn. Reson. Med. 2005; 53(2): 425-433.
21. Lu H, Clingman C, Golay X, van Zijl PC. Determining the longitudinal relaxation time (T1) of blood at 3.0 Tesla. Magn. Reson. Med. 2004; 52(3): 679-682.
22. Lu H, Nagae-Poetscher LM, Golay X, Lin D, Pomper M, van Zijl PC. Routine clinical brain MRI sequences for use at 3.0 Tesla. J. Magn. Reson. Imaging 2005; 22(1): 13-22.
23. MacIntosh BJ, Filippini N, Chappell MA, Woolrich MW, Mackay CE, Jezzard P. Assessment of arterial arrival times derived from multiple inversion time pulsed arterial spin labeling MRI. Magn. Reson. Med. 2010; 63(3): 641-647.
24. Ho YC, Petersen ET, Zimine I, Golay X. Similarities and differences in arterial responses to hypercapnia and visual stimulation. J. Cereb. Blood Flow Metab. 2011; 31(2): 560-571.
25. Jenkinson M, Bannister P, Brady M, Smith S. Improved optimization for the robust and accurate linear registration and motion correction of brain images. Neuroimage 2002; 17(2): 825-841.
26. Wise RG, Pattinson KT, Bulte DP, Chiarelli PA, Mayhew SD, Balanos GM, O'Connor DF, Pragnell TR, Robbins PA, Tracey I, Jezzard P. Dynamic forcing of end-tidal carbon dioxide and oxygen applied to functional magnetic resonance imaging. J. Cereb. Blood Flow Metab. 2007; 27(8): 1521-1532.
27. Robbins PA, Swanson GD, Micco AJ, Schubert WP. A fast gas-mixing system for breath-to-breath respiratory control studies. J. Appl. Physiol. 1982; 52(5): 1358-1362.
28. Steinback CD, Poulin MJ. Cardiovascular and cerebrovascular responses to acute isocapnic and poikilocapnic hypoxia in humans. J. Appl. Physiol. 2008; 104(2): 482-489.
29. Winn HR, Rubio R, Berne RM. Brain adenosine concentration during hypoxia in rats. Am. J. Physiol. Heart Circ. Physiol. 1981; 241: H235-H242.
30. Ainslie PN, Barach A, Murrell C, Hamlin M, Hellemans J, Ogoh S. Alterations in cerebral autoregulation and cerebral blood flow velocity during acute hypoxia: rest and exercise. Am. J. Physiol. Heart Circ. Physiol. 2007; 292: H976-H983.
31. Querido JS, Ainslie PN, Foster GE, Henderson WR, Halliwill JR, Ayas NT, Sheel AW. Dynamic cerebral autoregulation during and following acute hypoxia: role of carbon dioxide. J. Appl. Physiol. 2013; 114: 1183-1190.