Digital dermatitis in cattle is associated with an excessive innate immune response triggered by the keratinocytes

BMC Veterinary Research

Volumn 9, Issue , 2013, Pages

  Refaai, Walid ^a,b   Ducatelle, Richard ^a   Geldhof, Peter ^a   Mihi, Belgacem ^a   El shair, Mahasen ^b   Opsomer, Geert ^a  

^a GHENT UNIVERSITY   (Belgium)

^b Zagazig University   (Egypt)

Author keywords

Cattle; Cytokines; Digital dermatitis; Keratinocytes; Pathogenesis

Indexed keywords

BOS;

COMPLEMENTARY DNA; INTERLEUKIN 8; RNA;

ANIMAL; ANIMAL DISEASE; ARTICLE; CATTLE; CATTLE DISEASE; DERMATITIS; EOSINOPHIL; FEMALE; FOOT DISEASE; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; INNATE IMMUNITY; KERATINOCYTE; LYMPHOCYTE; METABOLISM; MOLECULAR CLONING; NEUTROPHIL; PATHOLOGY; PHYSIOLOGY; REAL TIME POLYMERASE CHAIN REACTION;

ANIMALS; CATTLE; CATTLE DISEASES; CLONING, MOLECULAR; DERMATITIS; DNA, COMPLEMENTARY; EOSINOPHILS; FEMALE; FOOT DISEASES; GENE EXPRESSION REGULATION; IMMUNITY, INNATE; INTERLEUKIN-8; KERATINOCYTES; LYMPHOCYTES; NEUTROPHILS; REAL-TIME POLYMERASE CHAIN REACTION; RNA;

EID: 84888041305     PISSN: None     EISSN: 17466148     Source Type: Journal    
DOI: 10.1186/1746-6148-9-193     Document Type: Article

References (32)

1. Bruijnis MRN, Hogeveen H, Stassen EN. Assessing economic consequences of foot disorders in dairy cattle using a dynamic stochastic simulation model. J Dairy Sci 2010, 93:2419-2432. 10.3168/jds.2009-2721, 20494150.
2. Cheli R, Mortellaro CM. La dermatite digitale del bovino 1974, 208-213. Milan, Italy: In Int Conf Diseases Cattle.
3. Refaai W, Van Aert M, Abd El-Aal AM, Behery AE, Opsomer G. Infectious diseases causing lameness in cattle with a main emphasis on Digital Dermatitis (Mortellaro disease). Livestock Science 2013, 156:53-63.
4. Read DH, Walker RL. Papillomatous digital dermatitis footwarts in California dairy cattle, clinical and gross pathologic findings. J Vet Diagn Invest 1998, 10:67-76. 10.1177/104063879801000112, 9526863.
5. Döpfer D, Holzhauer M, van Boven M. The dynamics of digital dermatitis in populations of dairy cattle: Model-based estimates of transition rates and implications for control. Vet J 2012, 193:648-653. 10.1016/j.tvjl.2012.06.047, 22878094.
6. Blowey RW, Sharp MW. Digital dermatitis in dairy cattle. Vet Rec 1988, 122:505-508. 10.1136/vr.122.21.505, 3407109.
7. El-Ghoul W, Shaheed BI. Ulcerative and papillomatous digital dermatitis of the pastern region in dairy cattle, clinical and histopathological studies. Dtsch Tierarzti Wochenschr 2001, 1085:216-222.
8. Döpfer DA, Koopmans FA, Meijer I, Szakall YH, Schukken W, Klee RB, Bosma JL, Cornelisse AJAM, van Asten AAHM, Ter Huurne AAHM. Histological and bacteriological evaluation of digital dermatitis in cattle, with special reference to Spirochaetes and Campylobacter faecalis. Vet Rec 1997, 140:620-623. 10.1136/vr.140.24.620, 9228692.
9. Cruz CE, Pescador CA, Nakajima Y, Driemeier D. Immunopathological investigations on bovine digital epidermitis. Vet Rec 2005, 157:834-840.
10. Logue D. Understanding bovine digital dermatitis. Vet Rec 2011, 168:212-213. 10.1136/vr.d1284, 21493553.
11. Nordhoff M, Moter A, Schrank K, Wieler LH. High prevalence of treponemes in bovine digital dermatitis - A molecular epidemiology. Vet Microbiol 2008, 131:293-300. 10.1016/j.vetmic.2008.04.019, 18524502.
12. Evans NJ, Brown JM, Demirkan I, Murray RD, Vink WD, Blowey RW, Hart CA, Carter SD. Three unique groups of spirochetes isolated from digital dermatitis lesions in UK cattle. Vet Microbiol 2008, 130:141-150. 10.1016/j.vetmic.2007.12.019, 18243592.
13. Rodriguez-Lainz A, Hird DW, Carpenter TE, Read DH. Case-control study of papillomatous digital dermatitis in southern California dairy farms. Prev Vet Med 1996, 28:117-131.
14. Gomez A, Cook NB, Bernardoni ND, Rieman J, Dusick AF, Hartshorn R, Socha MT, Read DH, Döpfer D. An experimental infection model to induce digital dermatitis infection in cattle. J Dairy Sci 2012, 95:1821-1830. 10.3168/jds.2011-4754, 22459830.
15. Holzhauer M, Hardenberg C, Bartels CJ, Frankena K. Herd and cow-level prevalence of digital dermatitis in the Netherlands and associated risk factors. J Dairy Sci 2006, 89:580-588. 10.3168/jds.S0022-0302(06)72121-X, 16428627.
16. Brown CC, Kilgo PD, Jacobsen KL. Prevalence of papillomatous digital dermatitis among culled adult cattle in the southeastern United States. Am J Vet Res 2000, 61:928-930. 10.2460/ajvr.2000.61.928, 10951985.
17. Koenig S, Sharifi AR, Wentrot H, Landmann D, Eise M, Simianer H. Genetic parameters of claw and foot disorders estimated with logistic models. J Dairy Sci 2005, 889:3316-3325.
18. van der Waaij EH, Holzhauer M, Ellen E, Kamphuis C, de Jong G. Genetic parameters for claw disorders in Dutch dairy cattle and correlations with conformation traits. J Dairy Sci 2005, 88:3672-3678. 10.3168/jds.S0022-0302(05)73053-8, 16162542.
19. Onyiro OM, Andrews LJ, Brotherstone S. Genetic parameters for digital dermatitis and correlations with locomotion, production, fertility traits, and longevity in Holstein-Friesian dairy cows. J Dairy Sci 2008, 91:4037-4046. 10.3168/jds.2008-1190, 18832230.
20. Scholey RA, Blowey RW, Murray RD, Smith RF, Cameron J, Massey JP, Ollier WE, Carter SD. Investigating host genetic factors in bovine digital dermatitis. Vet Rec 2012, 171:624. doi:10.1136/vr.101251.
21. Mihi B, Rinaldi M, Geldhof P. Effect of an Ostertagia ostertagi infection on the transcriptional stability of housekeeping genes in the bovine abomasums. Vet Parasitol 2011, 181:354-359. 10.1016/j.vetpar.2011.04.009, 21561716.
22. Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real time quantitative PCR and the 2-ΔΔCT method. Methods 2001, 25:402-408. 10.1006/meth.2001.1262, 11846609.
23. Krueger JG, Bowcock A. Psoriasis pathophysiology: current concepts of pathogenesis. Ann Rheum Dis 2005, 64(Suppl II):ii30-ii36. 1766865, 15708932.
24. Baggiolini M. Chemokines and leukocyte traffic. Nature 1998, 392:565-568. 10.1038/33340, 9560152.
25. Mitchell G, Albright B, Caswell J. Effect of interleukin-8 and granulocyte colony-stimulating factor on priming and activation of bovine neutrophils. Infect Immun 2003, 71:1643-1649. 10.1128/IAI.71.4.1643-1649.2003, 152050, 12654776.
26. Jiang WG, Sanders AJ, Ruge F, Harding KG. Influence of interleukin-8 (IL-8) and IL-8 receptors on the migration of human keratinocytes, the role of PLC-γ and potential clinical implications. Exp Ther Med 2012, 3:231-236. 3438606, 22969874.
27. Tuschil A, Lam C, Haslberger A, Lindley I. Interleukin-8 stimulates calcium transients and promotes epidermal cell proliferation. J Invest Dermatol 1992, 99:294-298. 10.1111/1523-1747.ep12616634, 1512465.
28. Sticherling M, Bornscheuer E, Schroder J-M, Christophers E. Localization of neutrophil-activating peptide-1/interleukin-8-immunoreactivity in normal and psoriatic skin. J Invest Dermatol 1991, 96:26-30. 10.1111/1523-1747.ep12514689, 1702820.
29. Mirandola P, Gobbi G, Micheloni C, Vaccarezza M, Marcantonio DD, Ruscitti F, Panfilis GD, Vitale M. Hydrogen sulfide inhibits IL-8 expression in human keratinocytes via MAP kinase signaling. Lab Invest 2011, 91:1188-1194. 10.1038/labinvest.2011.76, 21555999.
30. Meade KM, O'Gorman GM, Narciandi F, MacHugh DE, O'Farrelly C. Functional characterization of bovine interleukin 8 promotor haplotypes in vitro. Mol Immunol 2012, 50:108-116. 10.1016/j.molimm.2011.12.011, 22244152.
31. Galvao KN, Pighetti GM, Cheong SH, Nydam DV, Gilbert RO. Association between interleukin-8 receptor-α (CXCR1) polymorphism and disease incidence, production, reproduction and survival in Holstein cows. J Dairy Sci 2011, 94:2083-2091. 10.3168/jds.2010-3636, 21426999.
32. Verbeke J, Piepers S, Peelman L, Van Poucke M, De Vliegher S. Pathogen-group specific association between CXCR1 polymorphisms and subclinical mastitis in dairy heifers. J Dairy Res 2012, 79:341-351. 10.1017/S0022029912000349, 22850581.