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A Toxicologic and Dermatologic Assessment of Alkyl Cyclic Ketones When Used as Fragrance Ingredients
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The identification of contact allergens by animal assay. The guinea pig maximization test
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Kligman A.M. The identification of contact allergens by animal assay. The guinea pig maximization test. Journal of Investigative Dermatology 1969, 52(3):268-276.
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RIFM (Research Institute for Fragrance Materials, Inc.). 1,6-Heptadien-3-one, 2-cyclohexyl-(pharaone): Acute oral toxicity study in rats, Report number 59371, RIFM, Woodcliff Lake, NJ, USA.
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RIFM (Research Institute for Fragrance Materials, Inc.), 2001a. 1,6-Heptadien-3-one, 2-cyclohexyl-(pharaone): Acute oral toxicity study in rats, Report number 59371, RIFM, Woodcliff Lake, NJ, USA.
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RIFM (Research Institute for Fragrance Materials, Inc.). 1,6-Heptadien-3-one, 2-cyclohexyl- (pharaone): Contact hypersensitivity in albino guinea pigs, maximization-test. 04 December, Report number 59410, RIFM, Woodcliff Lake, NJ, USA.
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RIFM (Research Institute for Fragrance Materials, Inc.), 2001b. 1,6-Heptadien-3-one, 2-cyclohexyl- (pharaone): Contact hypersensitivity in albino guinea pigs, maximization-test. 04 December, Report number 59410, RIFM, Woodcliff Lake, NJ, USA.
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84888039893
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RIFM (Research Institute for Fragrance Materials, Inc.). 1,6-Heptadien-3-one, 2-cyclohexyl-(pharaone): Primary skin irritation study in rabbits (4-hour semi-occlusive application), Report number 59379, RIFM, Woodcliff Lake, NJ, USA.
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RIFM (Research Institute for Fragrance Materials, Inc.), 2001c. 1,6-Heptadien-3-one, 2-cyclohexyl-(pharaone): Primary skin irritation study in rabbits (4-hour semi-occlusive application), Report number 59379, RIFM, Woodcliff Lake, NJ, USA.
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9
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RIFM (Research Institute for Fragrance Materials, Inc.). Salmonella typhimurium reverse mutation assay with 1,6-heptadien-3-one, 2-cyclohexyl-(pharaone) (Amendment Attached). 16 November. Report number 59404, RIFM, Woodcliff Lake, NJ, USA.
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RIFM (Research Institute for Fragrance Materials, Inc.), 2001d. Salmonella typhimurium reverse mutation assay with 1,6-heptadien-3-one, 2-cyclohexyl-(pharaone) (Amendment Attached). 16 November. Report number 59404, RIFM, Woodcliff Lake, NJ, USA.
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10
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RIFM (Research Institute for Fragrance Materials, Inc.), 1,6-Heptadien-3-one, 2-cyclohexyl- (pharaone): Determination of photoallergenicity in albino guinea pigs (including information about allergenicity, photoirritation and irritation). 15 February. Report number 59408, RIFM, Woodcliff Lake, NJ, USA.
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RIFM (Research Institute for Fragrance Materials, Inc.), 2002. 1,6-Heptadien-3-one, 2-cyclohexyl- (pharaone): Determination of photoallergenicity in albino guinea pigs (including information about allergenicity, photoirritation and irritation). 15 February. Report number 59408, RIFM, Woodcliff Lake, NJ, USA.
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RIFM (Research Institute for Fragrance Materials, Inc.). Repeated insult patch test with 1,6-heptadien-3-one, 2-cyclohexyl- (pharaone). 24 January. Report number 59411, RIFM, Woodcliff Lake, NJ, USA.
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RIFM (Research Institute for Fragrance Materials, Inc.), 2003. Repeated insult patch test with 1,6-heptadien-3-one, 2-cyclohexyl- (pharaone). 24 January. Report number 59411, RIFM, Woodcliff Lake, NJ, USA.
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(2003)
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12
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84888056666
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RIFM (Research Institute for Fragrance Materials, Inc.). 1,6-Heptadien-3-one, 2-cyclohexyl-(pharaone): Acute dermal toxicity study in rats. Report number 59370, RIFM, Woodcliff Lake, NJ, USA.
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RIFM (Research Institute for Fragrance Materials, Inc.), 2004a. 1,6-Heptadien-3-one, 2-cyclohexyl-(pharaone): Acute dermal toxicity study in rats. Report number 59370, RIFM, Woodcliff Lake, NJ, USA.
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84888051129
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RIFM (Research Institute for Fragrance Materials, Inc.). Five day dose range finding and 28-day oral toxicity (gavage) study and 5 day range-finding oral toxicity study in the Wistar rat with 1,6-heptadien-3-one, 2-cyclohexyl- (pharaone). 21 May, Report number 59412, RIFM, Woodcliff Lake, NJ, USA.
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RIFM (Research Institute for Fragrance Materials, Inc.), 2004b. Five day dose range finding and 28-day oral toxicity (gavage) study and 5 day range-finding oral toxicity study in the Wistar rat with 1,6-heptadien-3-one, 2-cyclohexyl- (pharaone). 21 May, Report number 59412, RIFM, Woodcliff Lake, NJ, USA.
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RIFM (Research Institute for Fragrance Materials, Inc.). In vitro chromosome aberration test in Chinese hamster V79 cells with 1,6-heptadien-3-one, 2-cyclohexyl-(pharaone). Report number 59406, RIFM, Woodcliff Lake, NJ, USA.
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RIFM (Research Institute for Fragrance Materials, Inc.), 2004c. In vitro chromosome aberration test in Chinese hamster V79 cells with 1,6-heptadien-3-one, 2-cyclohexyl-(pharaone). Report number 59406, RIFM, Woodcliff Lake, NJ, USA.
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15
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RIFM (Research Institute for Fragrance Materials, Inc.). Micronucleus assay in bone marrow cells of the mouse with 1,6-heptadien-3-one, 2-cyclohexyl-(pharaone), 12 April, Report number 59407, RIFM, Woodcliff Lake, NJ, USA.
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RIFM (Research Institute for Fragrance Materials, Inc.), 2005. Micronucleus assay in bone marrow cells of the mouse with 1,6-heptadien-3-one, 2-cyclohexyl-(pharaone), 12 April, Report number 59407, RIFM, Woodcliff Lake, NJ, USA.
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RIFM (Research Institute for Fragrance Materials, Inc.). Escherichia coli reverse mutation assay with 1,6-heptadien-3-one, 2-cyclohexyl- (pharaone), 20 September, Report number 59405, RIFM, Woodcliff Lake, NJ, USA.
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RIFM (Research Institute for Fragrance Materials, Inc.), 2007. Escherichia coli reverse mutation assay with 1,6-heptadien-3-one, 2-cyclohexyl- (pharaone), 20 September, Report number 59405, RIFM, Woodcliff Lake, NJ, USA.
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(2007)
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