Associations of maternal 25-hydroxyvitamin D in pregnancy with offspring cardiovascular risk factors in childhood and adolescence: Findings from the avon longitudinal study of parents and children

Heart

Volumn 99, Issue 24, 2013, Pages 1849-1856

  Williams, Dylan M ^a   Fraser, Abigail ^a   Fraser, William D ^b   Hyppon̈en, Elina ^c   Smith, George Davey ^a   Deanfield, John ^c   Hingorani, Aroon ^d   Sattar, Naveed ^e   Lawlor, Debbie A ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b UNIVERSITY OF EAST ANGLIA   (United Kingdom)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

^d UNIVERSITY COLLEGE LONDON   (United Kingdom)

^e UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

25 HYDROXYVITAMIN D; APOLIPOPROTEIN; APOLIPOPROTEIN A1; APOLIPOPROTEIN B; C REACTIVE PROTEIN; GLUCOSE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INSULIN; INTERLEUKIN 6; LOW DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL;

ADOLESCENCE; ADULT; ARTICLE; BIRTH WEIGHT; BLOOD PRESSURE; BLOOD SAMPLING; BODY MASS; CARDIOVASCULAR DISEASE; CARDIOVASCULAR RISK; CHILD; CHILDHOOD; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; EDUCATION; ETHNICITY; FEMALE; GESTATIONAL AGE; GLUCOSURIA; HUMAN; INSULIN RESISTANCE; LONGITUDINAL STUDY; MATERNAL HYPERTENSION; OBSERVATIONAL STUDY; PARITY; PHYSICAL ACTIVITY; PREECLAMPSIA; PREGNANCY; PREGNANCY DIABETES MELLITUS; PRESCHOOL CHILD; PRIORITY JOURNAL; PROGENY; PROSPECTIVE STUDY; SCHOOL CHILD; SMOKING; SOCIAL STATUS;

LIPIDS;

ADOLESCENT; ADULT; CARDIOVASCULAR DISEASES; CHILD; FEMALE; FOLLOW-UP STUDIES; GREAT BRITAIN; HUMANS; INCIDENCE; MATERNAL NUTRITIONAL PHYSIOLOGICAL PHENOMENA; PREGNANCY; PREGNANCY COMPLICATIONS; PROSPECTIVE STUDIES; RISK FACTORS; VITAMIN D; VITAMIN D DEFICIENCY; YOUNG ADULT;

EID: 84888025756     PISSN: 13556037     EISSN: 1468201X     Source Type: Journal    
DOI: 10.1136/heartjnl-2013-303678     Document Type: Article

References (30)

1. Bodnar LM, Simhan HN, Powers RW, et al. High prevalence of vitamin D insuffi ciency in black and white pregnant women residing in the northern United States and their neonates. J Nutr 2007;137:447-52.
2. Holick MF. Vitamin D deficiency. N Engl J Med 2007;357:266-81.
3. Kovacs CS. Vitamin D in pregnancy and lactation: maternal, fetal, and neonatal outcomes from human and animal studies. Am J Clin Nutr 2008;88:520S-8S.
4. Javaid MK, Crozier SR, Harvey NC, et al . Maternal vitamin D status during pregnancy and childhood bone mass at age 9 years: a longitudinal study. Lancet 2006;367:36-43.
5. Mahon P, Harvey N, Crozier S, et al. Low maternal vitamin D status and fetal bone development: cohort study. J Bone Miner Res 2010;25:14-19.
6. Fronczak CM, Baron AE, Chase HP, et al. In utero dietary exposures and risk of islet autoimmunity in children. Diabetes Care 2003;26:3237-42.
7. Camargo CA, Rifas-Shiman SL, Litonjua AA, et al. Maternal intake of vitamin D during pregnancy and risk of recurrent wheeze in children at 3 y of age. Am J Clin Nutr 2007;85:788-95.
8. Krishnaveni GV, Veena SR, Winder NR, et al. Maternal vitamin D status during pregnancy and body composition and cardiovascular risk markers in Indian children: the Mysore Parthenon Study. Am J Clin Nutr 2011;93:628-35.
9. Bodnar LM, Catov JM, Simhan HN, et al. Maternal vitamin D deficiency increases the risk of preeclampsia. J Clin Endocrinol Metab 2007;92:3517-22.
10. Bodnar LM, Catov JM, Zmuda JM, et al. Maternal serum 25-hydroxyvitamin D concentrations are associated with small-for-gestational age births in white women. J Nutr 2010;140:999-1006.
11. Leffelaar ER, Vrijkotte TG, van Eijsden M. Maternal early pregnancy vitamin D status in relation to fetal and neonatal growth: results of the multi-ethnic Amsterdam Born Children and their Development cohort. Br J Nutr 2010;104:108-17.
12. Powe CE, Seely EW, Rana S, et al. First trimester vitamin D, vitamin D binding protein, and subsequent preeclampsia. Hypertension 2010;56:758-63.
13. Morley R, Carlin JB, Pasco JA, et al. Maternal 25-hydroxyvitamin D and parathyroid hormone concentrations and offspring birth size. J Clin Endocrinol Metab 2006;91:906-12.
14. Geelhoed JJM, Fraser A, Tilling K, et al. Preeclampsia and gestational hypertension are associated with childhood blood pressure independently of family adiposity measures/clinical perspective. Circulation 2010;122:1192-9.
15. Lawlor DA, Hubinette A, Tynelius P, et al. Associations of gestational age and intrauterine growth with systolic blood pressure in a family-based study of 386 485 men in 331 089 families. Circulation 2007;115:562-8.
16. Huxley R, Owen CG, Whincup PH, et al. Is birth weight a risk factor for ischemic heart disease in later life? Am J Clin Nutr 2007;85:1244-50.
17. Fraser A, Williams D, Lawlor DA. Associations of serum 25-hydroxyvitamin D, parathyroid hormone and calcium with cardiovascular risk factors: analysis of 3 NHANES cycles (2001-2006). PLoS ONE 2010;5:e13882.
18. Williams D, Fraser A, Sayers A, et al. Associations of 25-hydroxyvitamin D2 and D3 with cardiovascular risk factors in childhood: cross-sectional findings from the Avon Longitudinal Study of Parents and Children. J Clin Endocrinol Metab 2012;97:1563-71.
19. Gale CR, Robinson SM, Harvey NC, et al. Maternal vitamin D status during pregnancy and child outcomes. Eur J Clin Nutr 2008;62:68-77.
20. Fraser A, Macdonald-Wallis C, Tilling K, et al. Cohort Profile: The Avon Longitudinal Study of Parents and Children: ALSPAC mothers cohort. International Journal of Epidemiology 2012; doi:10.1093/ije/dys066
21. Boyd A, Golding J, Macleod J, et al. Cohort Profile: The 'Children of the 90s'; the index offspring of The Avon Longitudinal Study of Parents and Children (ALSPAC). International Journal of Epidemiology 2012; doi:10.1093/ije/dys064
22. Royston P, Ambler G, Sauerbrei W. The use of fractional polynomials to model continuous risk variables in epidemiology. Int J Epidemiol 1999;28:964 -74.
23. Royston P. Multiple imputation of missing values. Stata J 2004;4:227-41.
24. Boekholdt SM, Arsenault BJ, Mora S, et al. Association of LDL cholesterol, non-HDL cholesterol, and apolipoprotein B levels with risk of cardiovascular events among patients treated with statins. JAMA 2012;307:1302- 9.
25. Matthews D, Hosker J, Rudenski A, et al. Homeostasis model assessment: insulin resistance and â cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 1985;28:412-19.
26. Spilianakis C, Lee G, Flavell R. Twisting the Th1/Th2 immune response via the retinoid X receptor: lessons from a genetic approach. Eur J Immunol 2005;35:3400-4.
27. Saito S, Sakai M. Th1/Th2 balance in preeclampsia. J Reprod Immunol 2003;59:161-73.
28. Camargo CA, Ingham T, Wickens K, et al. Cord-blood 25-hydroxyvitamin D levels and risk of respiratory infection, wheezing, and asthma. Pediatrics 2011;127:e180-7.
29. Hofmann JN, Yu K, Horst RL, et al. Long-term variation in serum 25-hydroxyvitamin D concentration among participants in the prostate, lung, colorectal, and ovarian cancer screening trial. Cancer Epidemiol Biomarkers 2010;19:927 -31.
30. Major JM, Graubard BI, Dodd KW, et al . Variability and reproducibility of circulating vitamin D in a nationwide US Population. J Clin Endocrinol Metab 2013;98:97-104.