Associations of 25-hydroxyvitamin D2 and D3 with cardiovascular risk factors in childhood: Cross-sectional findings from the Avon Longitudinal study of Parents and children

Journal of Clinical Endocrinology and Metabolism

Volumn 97, Issue 5, 2012, Pages 1563-1571

  Williams, Dylan M ^a   Fraser, Abigail ^a   Sayers, Adrian ^a   Fraser, William D ^b   Hingorani, Aroon ^c   Deanfield, John ^c   Smith, George Davey ^a   Sattar, Naveed ^d   Lawlor, Debbie A ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b UNIVERSITY OF EAST ANGLIA   (United Kingdom)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

^d UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

25 HYDROXYERGOCALCIFEROL; ADIPONECTIN; APOLIPOPROTEIN A1; APOLIPOPROTEIN B; C REACTIVE PROTEIN; CALCIFEDIOL; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INTERLEUKIN 6; LEPTIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL;

ARTICLE; BLOOD PRESSURE VARIABILITY; CARDIOVASCULAR DISEASE; CARDIOVASCULAR RISK; CHILD; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; DISEASE ASSOCIATION; HEART PROTECTION; HUMAN; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; ONSET AGE; PRIORITY JOURNAL; RISK ASSESSMENT; RISK FACTOR; RISK REDUCTION; SCHOOL CHILD; SEASONAL VARIATION; UPREGULATION; VITAMIN BLOOD LEVEL; VITAMIN SUPPLEMENTATION;

25-HYDROXYVITAMIN D 2; ADIPONECTIN; APOLIPOPROTEINS; BLOOD PRESSURE; C-REACTIVE PROTEIN; CALCIFEDIOL; CARDIOVASCULAR DISEASES; CHILD; CROSS-SECTIONAL STUDIES; FEMALE; HUMANS; INTERLEUKIN-6; LEPTIN; LIPIDS; MALE; RISK FACTORS;

EID: 84860753863     PISSN: 0021972X     EISSN: 19457197     Source Type: Journal    
DOI: 10.1210/jc.2011-2335     Document Type: Article

References (42)

1. Kilkkinen A, Knekt P, Aro A, Rissanen H, Marniemi J, Heliövaara M, Impivaara O, Reunanen A 2009 Vitamin D status and the risk of cardiovascular disease death. Am J Epidemiol 170:1032-1039
2. Wang TJ, Pencina MJ, Booth SL, Jacques PF, Ingelsson E, Lanier K, Benjamin EJ, D'Agostino RB, Wolf M, Vasan RS 2008 Vitamin D deficiency and risk of cardiovascular Disease. Circulation 117:503-511
3. Martins D, Wolf M, Pan D, Zadshir A, Tareen N, Thandhani R, Felsenfeld A, Levine B, Mehrotra R, Norris K 2007 Prevalence of cardiovascular risk factors and the serum levels of 25-hydroxyvitamin D in the United States: data from the third National Health and Nutrition Examination Survey. Arch Intern Med 167:1159-1165
4. Fraser A, Williams D, Lawlor DA 2010 Associations of serum 25-hydroxyvitamin D, parathyroid hormone and calcium with cardiovascular risk factors: analysis of 3 NHANES Cycles (2001-2006). PLoS ONE 5:e13882
5. Holick MF 2007 Vitamin D deficiency. N Engl J Med 357:266-281
6. Binkley N, Krueger D 2008 Evaluation and correction of low vitamin D status. Current Osteoporosis Reports 6:95-99
7. Glendenning P 2003 Issues of standardization and assay-specific clinical decision limits for the measurement of 25-hydroxyvitamin D. Am J Clin Nutr 77:522-523
8. Webber LS, Srinivasan SR, Wattigney WA, Berenson GS 1991 Tracking of serum lipids and lipoproteins from childhood to adulthood: the Bogalusa Heart Study. Am J Epidemiol 133:884-899
9. Chen X, Wang Y 2008 Tracking of blood pressure from childhood to adulthood-a systematic review and meta-regression analysis. Circulation 117:3171-3180
10. McCarro NP, Smith DG, Okash AM, McEwen J 2000 Blood pressure in young adulthood and mortality from cardiovascular disease. Lancet 355:1430-1431
11. Paffenbarger Jr RS, Wing AL 1969 Chronic disease in former college students. Am J Epidemiol 90:527-535
12. Williams DM, Frase RA, Lawlor DA 2011 Associations of vitamin D, parathyroid hormone and calcium with cardiovascular risk factors in U. S. adolescents. Heart 97:315-320
13. Reis JP, von Mühlen D, Miller 3rd ER, Michos ED, Appel LJ 2009 Vitamin D status and cardiometabolic risk factors in the United States adolescent population. Pediatrics 124:e371-e379
14. Kumar J, Muntner P, Kaskel FJ, Hailpern SM, Melamed ML 2009 Prevalence and associations of 25-hydroxyvitamin D deficiency in U. S. children: NHANES 2001-2004. Pediatrics 124:e362-e370
15. Ford ES, Zhao G, Tsai J, Li C 2011 Associations between concentrations of vitamin D and concentrations of insulin, glucose, and HbA1c among adolescents in the United States. Diabetes Care 34:646-648
16. Johnson MD, Nader NS, Weaver AL, Singh R, Kumar S 2010 Relation ships between 25-hydroxyvitamin D levels and plasma glucose and lipid levels in pediatric outpatients. J Pediatr 156:444-449
17. Rajakuma RK, delas Hera SJ, Chen TC, Le ES, Holick MF, Arslanian SA 2011 Vitamin D status, adiposity, and lipids in black American and Caucasian children. J Clin Endocrinol Metab 96:1560-1567
18. Kelly A, Brooks LJ, Dougherty S, Carlow DC, Zemel BS 2011 A cross-sectional study of vitamin D and insulin resistance in children. Arch Dis Child 96:447-452
19. Houghton LA, Vieth R 2006 The case against ergocalciferol (vitamin D-2) as a vitamin supplement. Am J Clin Nutr 84:694-697
20. Heaney RP, Recker RR, Grote J, Horst RL, Armas LAG 2011 Vitamin D3 is more potent than vitamin D2 in humans. J Clinl Endocrinol Metab 96:E447-E452
21. Thacher TD, Fischer PR, Obadofin MO, Levine MA, Singh RJ, Pettifor JM Comparison of metabolism of vitamins D2 and D3 in children with nutritional rickets. J Bone Miner Res 25:1988-1995
22. Pfeifer M, Begerow B, Minne HW, Nachtigall D, Hansen C 2001 Effects of a short-term vitamin D3 and calcium supplementation on blood pressure and parathyroid hormone levels in elderly women. J Clin Endocrinol Metab 86:1633-1637
23. Hsia J, Heiss G, Ren H, Allison M, Dolan NC, Greenland P, Heckbert SR, Johnson KC, Manson JE, Sidney S, Trevisan M 2007 Calcium/vitamin D supplementation and cardiovascular events. Circulation 115:846-854
24. Wallis DE, Penckofer S, Sizemore GW 2008 The "sunshine deficit" and cardiovascular disease. Circulation 118:1476-1485
25. Golding J, Pembrey M, Jones R 2001 ALSPAC-The Avon Longitudinal Study of Parents and Children-I. Study methodology. Paediatr Perinat Epidemiol 15:74-87
26. Friedewald WT, Levy RI, Fredrickson DS 1972 Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem 18:499-502
27. Clark EM, Ness AR, Tobias JH 2008 Vigorous physical activity increases fracture risk in children irrespective of bone mass: a prospective study of the independent risk factors for fractures inhealthy children. J Bone Miner Res 23:1012-1022
28. Emmett P 2009 Dietary assessment in the Avon Longitudinal Study of Parents and Children. Eur J Clin Nutr 63(Suppl 1):S38-S44
29. Hagströ ME, Hellma NP, Larsson TE, Ingelsso NE, Berglun DL, Sundström J, Melhus H, Held C, Lind L, Michaëlsson K, Arnlöv J 2009 Plasma parathyroid hormone and the risk of cardiovascular mortality in the community. Circulation 119:2765-2771
30. Lind L, Skarfors E, Berglund L, Lithell H, Ljunghall S 1997 Serum calcium: a new, independent, prospective risk factor for myocardial infarction in middle-aged men followed for 18 years. J Clin Epidemiol 50:967-973
31. Foley RN 2009 Phosphate levels and cardiovascular disease in the general population. Clin J Am Soc Nephrol 4:1136-1139
32. Forouhi NG, Luan J, Cooper A, Boucher BJ, Wareham NJ 2008 Baseline serum 25-hydroxyvitamin D Is predictive of future glycemic status and insulin resistance. Diabetes 57:2619-2625
33. Judd SE, Tangpricha V 2009 Vitamin D deficiency and risk for cardiovascular disease. Am J Med Sci 338:40-44
34. Brennan PJ, Greenberg G, Miall WE, Thompson SG 1982 Seasonal variation in arterial blood pressure. Br Med J (Clinical Res Ed) 285:919-923
35. Cook JR, Semple RK 2010 Hypoadiponectinemia-cause or consequence of human "insulin resistance?" J Clin Endocrinol Metab 95:1544-1554
36. Alemzadeh R, Kichler J, Babar G, Calhoun M 2008 Hypovitaminosis D inobese children and adolescents: relationship with adiposity, insulin sensitivity, ethnicity, and season. Metabolism 57:183-191
37. Wan GY, Jacobs EJ, McCullough ML, Rodrigue ZC, Thun MJ, Calle EE, Flanders WD 2009 Comparing methods for accounting for seasonal variability in a biomarker when only a single sample is available: insights from simulations based on serum 25-hydroxyvitamin D. Am J Epidemiol 170:88-94
38. Di Angelantoni OE, Sarwa RN, Perr YP, Kaptog ES, Ray KK, Thompson A, Wood AM, Lewington S, Sattar N, Packard CJ, Collins R, Thompson SG, Danesh J; The Emerging Risk Factors Collaboration 2009 Major lipids, apolipoproteins, and risk of vascular disease. JAMA 302:1993-2000
39. Hofmann JN, Yu K, Horst RL, Hayes RB, Purdue MP 2010 Longterm variationin serum 25-hydroxyvitamin D concentration among participants in the prostate, lung, colorectal, and ovarian cancer screening trial. Cancer Epidemiol Biomarkers Prev 19:927-931
40. Holick MF 2011 Vitamin D deficiency in 2010: health benefits of vitamin D and sunlight: a D-bate. Nat Rev Endocrinol 7:73-75
41. Shapses SA, Manson JE 2011 Vitamin D and prevention of cardiovascular disease and diabetes. JAMA 305:2565-2566
42. Lawlor DA, Harbord RM, Sterne JA, Timpson N, Davey Smith G 2008 Mendelian randomization: using genes as instruments for making causal inferences in epidemiology. Stat Med 27:1133-1163