Immunohistochemical profile of the penile urethra and differential expression of GATA3 in urothelial versus squamous cell carcinomas of the penile urethra

Human Pathology

Volumn 44, Issue 12, 2013, Pages 2760-2767

  Chaux, Alcides ^a,b   Han, Jeong S ^a,c   Lee, Stephen ^a   Gonzalez Roibon, Nilda ^a   Sharma, Rajni ^a   Burnett, Arthur L ^a   Cubilla, Antonio L ^d   Netto, George J ^a  

^a DEPARTMENT OF PATHOLOGY   (United States)

^b Norte University   (Paraguay)

^c KAISER PERMANENTE MEDICAL CENTER   (United States)

^d INSTITUTO DE PATOLOGÍA E INVESTIGACIÓN   (Paraguay)

Author keywords

CK20; CK7; GATA3; Immunohistochemistry; p63; Penile urethra; Squamous cell carcinoma; Urothelial carcinoma

Indexed keywords

PEPTIDES AND PROTEINS; PROTEIN CK20; PROTEIN CK7; PROTEIN P63; TRANSCRIPTION FACTOR GATA 3; UNCLASSIFIED DRUG;

ARTICLE; CANCER SURGERY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; PENILE URETHRA SQUAMOUS CELL CARCINOMA; PROTEIN EXPRESSION; SQUAMOUS CELL CARCINOMA; TISSUE MICROARRAY; TRANSITIONAL CELL CARCINOMA; WART VIRUS;

CK20; CK7; GATA3; IMMUNOHISTOCHEMISTRY; P63; PENILE URETHRA; SQUAMOUS CELL CARCINOMA; UROTHELIAL CARCINOMA;

AGED; CARCINOMA, SQUAMOUS CELL; CARCINOMA, TRANSITIONAL CELL; DIAGNOSIS, DIFFERENTIAL; GATA3 TRANSCRIPTION FACTOR; HUMANS; MALE; MIDDLE AGED; PENIS; TISSUE ARRAY ANALYSIS; TUMOR MARKERS, BIOLOGICAL; URETHRA; URETHRAL NEOPLASMS; UROTHELIUM;

EID: 84888024244     PISSN: 00468177     EISSN: 15328392     Source Type: Journal    
DOI: 10.1016/j.humpath.2013.07.023     Document Type: Article

References (30)

1. E.F. Velazquez, A. Soskin, and A. Bock Epithelial abnormalities and precancerous lesions of anterior urethra in patients with penile carcinoma: a report of 89 cases Mod Pathol 18 2005 917 923
2. F. Brimo, and J.I. Epstein Selected common diagnostic problems in urologic pathology: perspectives from a large consult service in genitourinary pathology Arch Pathol Lab Med 136 2012 360 371
3. E.A. Kurzrock, L.S. Baskin, and G.R. Cunha Ontogeny of the male urethra: theory of endodermal differentiation Differentiation 64 1999 115 122
4. R. Gillitzer, C. Hampel, C. Wiesner, B. Hadaschik, and J. Thüroff Single-institution experience with primary tumours of the male urethra BJU Int 101 2008 964 968
5. Y.B. Thyavihally, H.B. Tongaonkar, S.K. Srivastava, U. Mahantshetty, P. Kumar, and S.G. Raibhattanavar Clinical outcome of 36 male patients with primary urethral carcinoma: a single center experience Int J Urol 13 2006 716 720
6. G. Dalbagni, Z.-F. Zhang, L. Lacombe, and H.W. Herr Male urethral carcinoma: analysis of treatment outcome Urology 53 1999 1126 1132
7. C.P. Dinney, D.E. Johnson, D.A. Swanson, R.J. Babaian, and A.C. von Eschenbach Therapy and prognosis for male anterior urethral carcinoma: an update Urology 43 1994 506 514
8. E. Scosyrev, B.W. Ely, and E.M. Messing Do mixed histological features affect survival benefit from neoadjuvant platinum-based combination chemotherapy in patients with locally advanced bladder cancer? A secondary analysis of Southwest Oncology Group-Directed Intergroup Study (S8710) BJU Int 108 2011 693 699
9. L.J. Ko, M. Yamamoto, M.W. Leonard, K.M. George, P. Ting, and J.D. Engel Murine and human T-lymphocyte GATA-3 factors mediate transcription through a cis-regulatory element within the human T-cell receptor delta gene enhancer Mol Cell Biol 11 1991 2778 2784
10. G.E. Esheba, T.A. Longacre, K.A. Atkins, and J.P. Higgins Expression of the urothelial differentiation markers GATA3 and placental S100 (S100P) in female genital tract transitional cell proliferations Am J Surg Pathol 33 2009 347 353
11. J.P. Higgins, G. Kaygusuz, and L. Wang Placental S100 (S100P) and GATA3: markers for transitional epithelium and urothelial carcinoma discovered by complementary DNA microarray Am J Surg Pathol 31 2007 673 680
12. D. Yavuzer, N. Karadayi, T. Salepci, H. Baloglu, A. Bilici, and D. Sakirahmet Role of human papillomavirus in the development of urothelial carcinoma Med Oncol 28 2011 919 923
13. W. Ben Selma, S. Ziadi, and R. Ben Gacem Investigation of human papillomavirus in bladder cancer in a series of Tunisian patients Pathol Res Pract 206 2010 740 743
14. C. Miralles-Guri, L. Bruni, A.L. Cubilla, X. Castellsague, F.X. Bosch, and S. de Sanjose Human papillomavirus prevalence and type distribution in penile carcinoma J Clin Pathol 62 2009 870 878
15. A.L. Cubilla, B. Lloveras, and M. Alejo The basaloid cell is the best tissue marker for human papillomavirus in invasive penile squamous cell carcinoma: a study of 202 cases from Paraguay Am J Surg Pathol 34 2010 104 114
16. A.L. Cubilla, B. Lloveras, and L. Alemany Basaloid squamous cell carcinoma of the penis with papillary features: a clinicopathologic study of 12 cases Am J Surg Pathol 36 2012 869 875
17. H.L. Fedor, and A.M. De Marzo Practical methods for tissue microarray construction Methods Mol Med 103 2005 89 101
18. P.C. Black, G.A. Brown, and C.P.N. Dinney The impact of variant histology on the outcome of bladder cancer treated with curative intent Urol Oncol: Semin Orig Investig 27 2009 3 7
19. M.D. Galsky, A. Iasonos, and S. Mironov Prospective trial of ifosfamide, paclitaxel, and cisplatin in patients with advanced non-transitional cell carcinoma of the urothelial tract Urology 69 2007 255 259
20. A. Manunta, S. Vincendeau, G. Kiriakou, B. Lobel, and F. Guillé Non-transitional cell bladder carcinomas BJU Int 95 2005 497 502
21. E.J. Trabulsi, and J. Hoffman-Censits Chemotherapy for penile and urethral carcinoma Urol Clin North Am 37 2010 467 474
22. H. Miyamoto, K. Izumi, and J.L. Yao GATA binding protein 3 is down-regulated in bladder cancer yet strong expression is an independent predictor of poor prognosis in invasive tumor Hum Pathol 43 2012 2033 2040
23. A. Chang, A. Amin, and E. Gabrielson Utility of GATA3 immunohistochemistry in differentiating urothelial carcinoma from prostate adenocarcinoma and squamous cell carcinomas of the uterine cervix, anus, and lung Am J Surg Pathol 36 2012 1472 1476
24. C. Gulmann, G.P. Paner, and R.S. Parakh Immunohistochemical profile to distinguish urothelial from squamous differentiation in carcinomas of urothelial tract Hum Pathol 44 2013 164 172
25. A.M. Gruver, M.B. Amin, and D.J. Luthringer Selective immunohistochemical markers to distinguish between metastatic high-grade urothelial carcinoma and primary poorly differentiated invasive squamous cell carcinoma of the lung Arch Pathol Lab Med 136 2012 1339 1346
26. N.K. Yoon, E.L. Maresh, and D. Shen Higher levels of GATA3 predict better survival in women with breast cancer Hum Pathol 41 2010 1794 1801
27. J. Jacquemier, E. Charafe-Jauffret, and F. Monville Association of GATA3, P53, Ki67 status and vascular peritumoral invasion are strongly prognostic in luminal breast cancer Breast Cancer Res 11 2009 R23
28. A. Chaux, E.F. Velazquez, F. Algaba, G. Ayala, and A.L. Cubilla Developments in the pathology of penile squamous cell carcinomas Urology 76 2010 S7 S14
29. A. Chaux, P. Tamboli, and A. Ayala Warty-basaloid carcinoma: clinicopathological features of a distinctive penile neoplasm. Report of 45 cases Mod Pathol 23 2010 896 904
30. A.L. Cubilla, B. Lloveras, and M. Alejo Value of p16INKa in the pathology of invasive penile squamous cell carcinomas: a report of 202 cases Am J Surg Pathol 35 2011 253 261