Fragrance material review on 1-(3,5,6-trimethyl-3-cyclohexen-1-yl)ethan-1-one

Food and Chemical Toxicology

Volumn 62, Issue , 2013, Pages

  Scognamiglio, J ^a   Letizia, C S ^a   Api, A M ^a  

^a RESEARCH INSTITUTE FOR FRAGRANCE MATERIALS   (United States)

Author keywords

1 (3,5,6 Trimethyl 3 cyclohexen 1 yl)ethan 1 one; Fragrance material; Review

Indexed keywords

1 (3,5,6 TRIMETHYL 3 CYCLOHEXEN 1 YL)ETHAN 1 ONE; ALKYL GROUP; FRAGRANCE; HYDROCARBON; KETONE DERIVATIVE; UNCLASSIFIED DRUG;

ACUTE TOXICITY; CARCINOGENICITY; CHEMICAL ANALYSIS; CHEMICAL COMPOSITION; CHEMICAL STRUCTURE; EYE IRRITATION; GENOTOXICITY; HUMAN; NONHUMAN; PHOTOALLERGY; PHOTOTOXICITY; PHYSICAL CHEMISTRY; REPRODUCTIVE TOXICITY; REVIEW; RISK ASSESSMENT; SKIN ALLERGY; SKIN IRRITATION; SKIN SENSITIZATION; SKIN TOXICITY; TOXICOKINETICS;

1-(3,5,6-TRIMETHYL-3-CYCLOHEXEN-1-YL)ETHAN-1-ONE; FRAGRANCE MATERIAL; REVIEW;

ANIMALS; CONSUMER PRODUCT SAFETY; CYCLOHEXENES; DERMATITIS, PHOTOALLERGIC; DERMATITIS, PHOTOTOXIC; DRUG HYPERSENSITIVITY; EYE; HUMANS; IRRITANTS; PERFUME; SKIN; TOXICITY TESTS;

EID: 84888021722     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2013.08.059     Document Type: Review

References (6)

1. Belsito, D., Bickers, D., Bruze, M., Calow, P., Dagli, M., Fryer, A.D., Greim, H., Miyachi, Y., Saurat, J.H., Sipes, I.G., 2013. A Toxicologic and Dermatologic Assessment of Alkyl Cyclic Ketones When Used as Fragrance Ingredients (submitted for publication).
2. Cadby P., Troy W., Vey M. Consumer exposure to fragrance ingredients: providing estimates for safety evaluation. Regulatory Toxicology and Pharmacology 2002, 36:246-252.
3. EPA (Environmental Protection Agency), 2010. Estimation Programs Interface Suite™ for Microsoft™ Windows, v 4.00 or Insert Version Used. United States Environmental Protection Agency, Washington, DC, USA.
4. Ford R., Domeyer B., Easterday O., Maier K., Middleton J. Criteria for development of a database for safety evaluation of fragrance ingredients. Regulatory Toxicology and Pharmacology 2000, 31:166-181.
5. IFRA (International Fragrance Association), 2008. Volume of Use Survey, February 2008.
6. RIFM (Research Institute for Fragrance Materials, Inc.), 1965a. Repeated Insult Patch Test with 1-(3,5,6-trimethyl-3-cyclohexen-1-yl)ethan-1-one (Methyl Cyclo Citrone). Unpublished Report from International Flavors and Fragrances, 04 January. Report number 53551 RIFM, Woodcliff Lake, NJ, USA.