-
1
-
-
0036828784
-
The burden of hepatitis C in the United States
-
Kim W.R. The burden of hepatitis C in the United States. Hepatology 2002, 36:S30-S34.
-
(2002)
Hepatology
, vol.36
-
-
Kim, W.R.1
-
2
-
-
33646852746
-
The prevalence of hepatitis C virus infection in the United States, 1999 through 2002
-
Armstrong G.L., Wasley A., Simard E.P., et al. The prevalence of hepatitis C virus infection in the United States, 1999 through 2002. Ann Intern Med 2006, 144:705-714.
-
(2006)
Ann Intern Med
, vol.144
, pp. 705-714
-
-
Armstrong, G.L.1
Wasley, A.2
Simard, E.P.3
-
3
-
-
0037179698
-
Peginterferon alfa-2a plus ribavirin for chronic hepatitis C virus infection
-
Fried M.W., Shiffman M.L., Reddy K.R., et al. Peginterferon alfa-2a plus ribavirin for chronic hepatitis C virus infection. NEngl J Med 2002, 347:975-982.
-
(2002)
NEngl J Med
, vol.347
, pp. 975-982
-
-
Fried, M.W.1
Shiffman, M.L.2
Reddy, K.R.3
-
4
-
-
0035934568
-
Peginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus ribavirin for initial treatment of chronic hepatitis C: a randomised trial
-
Manns M.P., McHutchison J.G., Gordon S.C., et al. Peginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus ribavirin for initial treatment of chronic hepatitis C: a randomised trial. Lancet 2001, 358:958-965.
-
(2001)
Lancet
, vol.358
, pp. 958-965
-
-
Manns, M.P.1
McHutchison, J.G.2
Gordon, S.C.3
-
5
-
-
0032547938
-
Interferon alfa-2b alone or in combination with ribavirin as initial treatment for chronic hepatitis C. Hepatitis Interventional Therapy Group
-
McHutchison J.G., Gordon S.C., Schiff E.R., et al. Interferon alfa-2b alone or in combination with ribavirin as initial treatment for chronic hepatitis C. Hepatitis Interventional Therapy Group. NEngl J Med 1998, 339:1485-1492.
-
(1998)
NEngl J Med
, vol.339
, pp. 1485-1492
-
-
McHutchison, J.G.1
Gordon, S.C.2
Schiff, E.R.3
-
6
-
-
2442683905
-
Peginterferon alfa-2b plus ribavirin for treatment of chronic hepatitis C in previously untreated patients infected with HCV genotypes 2 or 3
-
Zeuzem S., Hultcrantz R., Bourliere M., et al. Peginterferon alfa-2b plus ribavirin for treatment of chronic hepatitis C in previously untreated patients infected with HCV genotypes 2 or 3. JHepatol 2004, 40:993-999.
-
(2004)
JHepatol
, vol.40
, pp. 993-999
-
-
Zeuzem, S.1
Hultcrantz, R.2
Bourliere, M.3
-
7
-
-
11144246127
-
Novel insights into hepatitis C virus replication and persistence
-
Bartenschlager R., Frese M., Pietschmann T. Novel insights into hepatitis C virus replication and persistence. Adv Virus Res 2004, 63:71-180.
-
(2004)
Adv Virus Res
, vol.63
, pp. 71-180
-
-
Bartenschlager, R.1
Frese, M.2
Pietschmann, T.3
-
8
-
-
0344201903
-
An NS3 protease inhibitor with antiviral effects in humans infected with hepatitis C virus
-
Lamarre D., Anderson P.C., Bailey M., et al. An NS3 protease inhibitor with antiviral effects in humans infected with hepatitis C virus. Nature 2003, 426:186-189.
-
(2003)
Nature
, vol.426
, pp. 186-189
-
-
Lamarre, D.1
Anderson, P.C.2
Bailey, M.3
-
9
-
-
77953207214
-
Review article: specifically targeted anti-viral therapy for hepatitis C-a new era in therapy
-
Lange C.M., Sarrazin C., Zeuzem S. Review article: specifically targeted anti-viral therapy for hepatitis C-a new era in therapy. Aliment Pharmacol Ther 2010, 32:14-28.
-
(2010)
Aliment Pharmacol Ther
, vol.32
, pp. 14-28
-
-
Lange, C.M.1
Sarrazin, C.2
Zeuzem, S.3
-
10
-
-
65449152185
-
Telaprevir with peginterferon and ribavirin for chronic HCV genotype 1 infection
-
McHutchison J.G., Everson G.T., Gordon S.C., et al. Telaprevir with peginterferon and ribavirin for chronic HCV genotype 1 infection. NEngl J Med 2009, 360:1827-1838.
-
(2009)
NEngl J Med
, vol.360
, pp. 1827-1838
-
-
McHutchison, J.G.1
Everson, G.T.2
Gordon, S.C.3
-
11
-
-
65449171953
-
Telaprevir and peginterferon with or without ribavirin for chronic HCV infection
-
Hezode C., Forestier N., Dusheiko G., et al. Telaprevir and peginterferon with or without ribavirin for chronic HCV infection. NEngl J Med 2009, 360:1839-1850.
-
(2009)
NEngl J Med
, vol.360
, pp. 1839-1850
-
-
Hezode, C.1
Forestier, N.2
Dusheiko, G.3
-
12
-
-
77950817619
-
Telaprevir for previously treated chronic HCV infection
-
McHutchison J.G., Manns M.P., Muir A.J., et al. Telaprevir for previously treated chronic HCV infection. NEngl J Med 2010, 362:1292-1303.
-
(2010)
NEngl J Med
, vol.362
, pp. 1292-1303
-
-
McHutchison, J.G.1
Manns, M.P.2
Muir, A.J.3
-
13
-
-
79251554986
-
Telaprevir is effective given every 8 or 12 hours with ribavirin and peginterferon alfa-2a or -2b to patients with chronic hepatitis C
-
Marcellin P., Forns X., Goeser T., et al. Telaprevir is effective given every 8 or 12 hours with ribavirin and peginterferon alfa-2a or -2b to patients with chronic hepatitis C. Gastroenterology 2011, 140(2):459-468.
-
(2011)
Gastroenterology
, vol.140
, Issue.2
, pp. 459-468
-
-
Marcellin, P.1
Forns, X.2
Goeser, T.3
-
14
-
-
78650820415
-
Telaprevir in combination with peginterferon and ribavirin in genotype 1 HCV treatment naive patients: final results of phase 3 ADVANCE study
-
Jacobson I.M., McHutchison J.G., Dusheiko G.M., et al. Telaprevir in combination with peginterferon and ribavirin in genotype 1 HCV treatment naive patients: final results of phase 3 ADVANCE study. Hepatology 2010, 52:427A.
-
(2010)
Hepatology
, vol.52
-
-
Jacobson, I.M.1
McHutchison, J.G.2
Dusheiko, G.M.3
-
15
-
-
78751626981
-
Telaprevir in combination with peginterferon alfa-2a and ribavirin for 24 or 48 weeks in treatment naive genotype 1 HCV patients who achieved an extended viral response: final results of phase 3 ILLUMINATE study
-
Sherman K.E., Flamm S.L., Afdhal N.H., et al. Telaprevir in combination with peginterferon alfa-2a and ribavirin for 24 or 48 weeks in treatment naive genotype 1 HCV patients who achieved an extended viral response: final results of phase 3 ILLUMINATE study. Hepatology 2010, 52:LB-2.
-
(2010)
Hepatology
, vol.52
-
-
Sherman, K.E.1
Flamm, S.L.2
Afdhal, N.H.3
-
16
-
-
84888043172
-
-
Vertex's and Tibotec [press release]; Cambridge (MA): Vertex Pharmaceuticals; September 7, 2010.
-
Vertex's and Tibotec [press release]; Cambridge (MA): Vertex Pharmaceuticals; September 7, 2010.
-
-
-
-
17
-
-
79951630741
-
Long term follow up of patients with chronic hepatitis C treated with telaprevir in combination with peginterferon alfa-2a and ribavirin: interim analysis of the EXTEND study
-
Zeuzem S., Sulkowski M.S., Zoulim F., et al. Long term follow up of patients with chronic hepatitis C treated with telaprevir in combination with peginterferon alfa-2a and ribavirin: interim analysis of the EXTEND study. Hepatology 2010, 52:436A.
-
(2010)
Hepatology
, vol.52
-
-
Zeuzem, S.1
Sulkowski, M.S.2
Zoulim, F.3
-
18
-
-
77956268467
-
Efficacy of boceprevir, an NS3 protease inhibitor, in combination with peginterferon alfa-2b and ribavirin in treatment-naive patients with genotype 1 hepatitis C infection (SPRINT-1): an open-label, randomised, multicentre phase 2 trial
-
Kwo P.Y., Lawitz E.J., McCone J., et al. Efficacy of boceprevir, an NS3 protease inhibitor, in combination with peginterferon alfa-2b and ribavirin in treatment-naive patients with genotype 1 hepatitis C infection (SPRINT-1): an open-label, randomised, multicentre phase 2 trial. Lancet 2010, 376:705-716.
-
(2010)
Lancet
, vol.376
, pp. 705-716
-
-
Kwo, P.Y.1
Lawitz, E.J.2
McCone, J.3
-
19
-
-
79953173221
-
Boceprevir with peginterferon/ribavirin for untreated chronic hepatitis C
-
Poordad F., McCone J., Bacon B., et al. Boceprevir with peginterferon/ribavirin for untreated chronic hepatitis C. NEngl J Med 2011, 364:1195-1206.
-
(2011)
NEngl J Med
, vol.364
, pp. 1195-1206
-
-
Poordad, F.1
McCone, J.2
Bacon, B.3
-
20
-
-
79953176289
-
Boceprevir for treatment-resistant chronic HCV genotype 1 infection
-
Bacon B., Gordon S., Lawitz E., et al. Boceprevir for treatment-resistant chronic HCV genotype 1 infection. NEngl J Med 2011, 364:1207-1217.
-
(2011)
NEngl J Med
, vol.364
, pp. 1207-1217
-
-
Bacon, B.1
Gordon, S.2
Lawitz, E.3
-
21
-
-
80051945658
-
Four-week therapy with peginterferon alfa-2b/ribavirin effectively predicts sustained virologic response in treatment-naive and treatment-experienced patients with HCV-1 treated with boceprevir plus peginterferon alfa-2b/ribavirin
-
Vierling J., Lawitz E., Poordad F., et al. Four-week therapy with peginterferon alfa-2b/ribavirin effectively predicts sustained virologic response in treatment-naive and treatment-experienced patients with HCV-1 treated with boceprevir plus peginterferon alfa-2b/ribavirin. JHepatol 2011, 54:S197.
-
(2011)
JHepatol
, vol.54
-
-
Vierling, J.1
Lawitz, E.2
Poordad, F.3
-
22
-
-
80051936627
-
Predictors of sustained virologic response among treatment-experienced patients with hepatitis C virus genotype 1 when re-treated with boceprevir plus peginterferon alfa-2b/ribavirin
-
Zeuzem S., Vierling J., Estaban R., et al. Predictors of sustained virologic response among treatment-experienced patients with hepatitis C virus genotype 1 when re-treated with boceprevir plus peginterferon alfa-2b/ribavirin. JHepatol 2011, 54:S199.
-
(2011)
JHepatol
, vol.54
-
-
Zeuzem, S.1
Vierling, J.2
Estaban, R.3
-
23
-
-
34247594930
-
Dynamic hepatitis C virus genotypic and phenotypic changes in patients treated with the protease inhibitor telaprevir
-
Sarrazin C., Kieffer T.L., Bartels D., et al. Dynamic hepatitis C virus genotypic and phenotypic changes in patients treated with the protease inhibitor telaprevir. Gastroenterology 2007, 132:1767-1777.
-
(2007)
Gastroenterology
, vol.132
, pp. 1767-1777
-
-
Sarrazin, C.1
Kieffer, T.L.2
Bartels, D.3
-
24
-
-
27744529265
-
Invitro studies of cross-resistance mutations against two hepatitis C virus serine protease inhibitors, VX-950 and BILN 2061
-
Lin C., Gates C.A., Rao B.G., et al. Invitro studies of cross-resistance mutations against two hepatitis C virus serine protease inhibitors, VX-950 and BILN 2061. JBiol Chem 2005, 280:36784-36791.
-
(2005)
JBiol Chem
, vol.280
, pp. 36784-36791
-
-
Lin, C.1
Gates, C.A.2
Rao, B.G.3
-
25
-
-
9644275435
-
Combination of a hepatitis C virus NS3-NS4A protease inhibitor and α interferon synergistically inhibits viral RNA replication and facilitates viral RNA clearance in replicon cells
-
Lin K., Kwong A.D., Lin C. Combination of a hepatitis C virus NS3-NS4A protease inhibitor and α interferon synergistically inhibits viral RNA replication and facilitates viral RNA clearance in replicon cells. Antimicrob Agents Chemother 2004, 48:4784-4792.
-
(2004)
Antimicrob Agents Chemother
, vol.48
, pp. 4784-4792
-
-
Lin, K.1
Kwong, A.D.2
Lin, C.3
-
26
-
-
33646446894
-
VX-950, a novel hepatitis C virus (HCV) NS3-4A protease inhibitor, exhibits potent antiviral activities in HCv replicon cells
-
Lin K., Perni R.B., Kwong A.D., et al. VX-950, a novel hepatitis C virus (HCV) NS3-4A protease inhibitor, exhibits potent antiviral activities in HCv replicon cells. Antimicrob Agents Chemother 2006, 50:1813-1822.
-
(2006)
Antimicrob Agents Chemother
, vol.50
, pp. 1813-1822
-
-
Lin, K.1
Perni, R.B.2
Kwong, A.D.3
-
27
-
-
34548758435
-
Telaprevir and pegylated interferon-α-2a inhibit wild-type and resistant genotype 1 hepatitis C virus replication in patients
-
Kieffer T.L., Sarrazin C., Miller J.S., et al. Telaprevir and pegylated interferon-α-2a inhibit wild-type and resistant genotype 1 hepatitis C virus replication in patients. Hepatology 2007, 46:631-639.
-
(2007)
Hepatology
, vol.46
, pp. 631-639
-
-
Kieffer, T.L.1
Sarrazin, C.2
Miller, J.S.3
-
28
-
-
66149128046
-
GT-1a or GT-1b subtype-specific resistance profiles for hepatitis C virus inhibitors telaprevir and HCV-796
-
McCown M.F., Rajyaguru S., Kular S., et al. GT-1a or GT-1b subtype-specific resistance profiles for hepatitis C virus inhibitors telaprevir and HCV-796. Antimicrob Agents Chemother 2009, 53:2129-2132.
-
(2009)
Antimicrob Agents Chemother
, vol.53
, pp. 2129-2132
-
-
McCown, M.F.1
Rajyaguru, S.2
Kular, S.3
-
29
-
-
33646036163
-
Identification and analysis of fitness of resistance mutations against the HCV protease inhibitor SCH 503034
-
Tong X., Chase R., Skelton A., et al. Identification and analysis of fitness of resistance mutations against the HCV protease inhibitor SCH 503034. Antiviral Res 2006, 70:28-38.
-
(2006)
Antiviral Res
, vol.70
, pp. 28-38
-
-
Tong, X.1
Chase, R.2
Skelton, A.3
-
30
-
-
79953764145
-
Long term outcomes following combination treatment with boceprevir plus pegintron/ribavirin (P/R) in patients with chronic hepatitis C genotype 1 (CHC-G1)
-
Vierling J.M., Ralston R., Lawitz E., et al. Long term outcomes following combination treatment with boceprevir plus pegintron/ribavirin (P/R) in patients with chronic hepatitis C genotype 1 (CHC-G1). JHepatol 2010, 52:S470.
-
(2010)
JHepatol
, vol.52
-
-
Vierling, J.M.1
Ralston, R.2
Lawitz, E.3
-
31
-
-
84877739274
-
POSITRON Study; FUSION Study. Sofosbuvir for hepatitis C genotype 2 or 3 patients without treatment options
-
Jacobson I.M., Gordon S.C., Kowdley K.V., et al. POSITRON Study; FUSION Study. Sofosbuvir for hepatitis C genotype 2 or 3 patients without treatment options. N Engl J Med 2013 May 16, 368(20):1867-1877.
-
(2013)
N Engl J Med
, vol.368
, Issue.20
, pp. 1867-1877
-
-
Jacobson, I.M.1
Gordon, S.C.2
Kowdley, K.V.3
-
32
-
-
84877730954
-
Sofosbuvir for previously untreated chronic hepatitis C infection
-
Lawitz E., Mangia A., Wyles D., et al. Sofosbuvir for previously untreated chronic hepatitis C infection. N Engl J Med 2013 May 16, 368(20):1878-1887.
-
(2013)
N Engl J Med
, vol.368
, Issue.20
, pp. 1878-1887
-
-
Lawitz, E.1
Mangia, A.2
Wyles, D.3
-
33
-
-
34547618419
-
Non-nucleoside inhibitors of the HCV NS5B polymerase: progress in the discovery and development of novel agents for the treatment of HCV infections
-
Beaulieu P.L. Non-nucleoside inhibitors of the HCV NS5B polymerase: progress in the discovery and development of novel agents for the treatment of HCV infections. Curr Opin Investig Drugs 2007, 8:614-634.
-
(2007)
Curr Opin Investig Drugs
, vol.8
, pp. 614-634
-
-
Beaulieu, P.L.1
-
34
-
-
49649125855
-
R1626 plus peginterferon Alfa-2a provides potent suppression of hepatitis C virus RNA and significant antiviral synergy in combination with ribavirin
-
Pockros P.J., Nelson D., Godofsky E., et al. R1626 plus peginterferon Alfa-2a provides potent suppression of hepatitis C virus RNA and significant antiviral synergy in combination with ribavirin. Hepatology 2008, 48:385-397.
-
(2008)
Hepatology
, vol.48
, pp. 385-397
-
-
Pockros, P.J.1
Nelson, D.2
Godofsky, E.3
-
35
-
-
77950203857
-
Viral resistance to specifically targeted antiviral therapies for hepatitis C (STAT-Cs)
-
Kieffer T.L., Kwong A.D., Picchio G.R. Viral resistance to specifically targeted antiviral therapies for hepatitis C (STAT-Cs). JAntimicrob Chemother 2010, 65:202-212.
-
(2010)
JAntimicrob Chemother
, vol.65
, pp. 202-212
-
-
Kieffer, T.L.1
Kwong, A.D.2
Picchio, G.R.3
-
36
-
-
67049145581
-
Preclinical characterization of PF-00868554, a potent nonnucleoside inhibitor of the hepatitis C virus RNA-dependent RNA polymerase
-
Shi S.T., Herlihy K.J., Graham J.P., et al. Preclinical characterization of PF-00868554, a potent nonnucleoside inhibitor of the hepatitis C virus RNA-dependent RNA polymerase. Antimicrob Agents Chemother 2009, 53:2544-2552.
-
(2009)
Antimicrob Agents Chemother
, vol.53
, pp. 2544-2552
-
-
Shi, S.T.1
Herlihy, K.J.2
Graham, J.P.3
-
37
-
-
80051820156
-
Mechanistic characterization of GS-9190 (Tegobuvir), a novel nonnucleoside inhibitor of hepatitis C virus NS5B polymerase
-
Shih I.H., Vliegen I., Peng B., et al. Mechanistic characterization of GS-9190 (Tegobuvir), a novel nonnucleoside inhibitor of hepatitis C virus NS5B polymerase. Antimicrob Agents Chemother 2011 Sep, 55(9):4196-4203.
-
(2011)
Antimicrob Agents Chemother
, vol.55
, Issue.9
, pp. 4196-4203
-
-
Shih, I.H.1
Vliegen, I.2
Peng, B.3
-
38
-
-
78650971116
-
Once daily NS5A Inhibitor(BMS-790052) plus peginterferon-α 2a and ribavirin produces high rates of extended rapid virologic response in treatment naive HCV genotype 1 subjects: phase 2a trial
-
Pol S., Everson G., Ghalib S., et al. Once daily NS5A Inhibitor(BMS-790052) plus peginterferon-α 2a and ribavirin produces high rates of extended rapid virologic response in treatment naive HCV genotype 1 subjects: phase 2a trial. Hepatology 2010, 52:S462.
-
(2010)
Hepatology
, vol.52
-
-
Pol, S.1
Everson, G.2
Ghalib, S.3
-
39
-
-
78049527728
-
Oral combination therapy with a nucleoside polymerase inhibitor (RG7128) and danoprevir for chronic hepatitis C genotype 1 infection (INFORM-1): a randomised, double-blind, placebo-controlled, dose-escalation trial
-
Gane E.J., Roberts S.K., Stedman C.A., et al. Oral combination therapy with a nucleoside polymerase inhibitor (RG7128) and danoprevir for chronic hepatitis C genotype 1 infection (INFORM-1): a randomised, double-blind, placebo-controlled, dose-escalation trial. Lancet 2010, 376:1467-1475.
-
(2010)
Lancet
, vol.376
, pp. 1467-1475
-
-
Gane, E.J.1
Roberts, S.K.2
Stedman, C.A.3
-
40
-
-
84888059055
-
-
A study on the combination of RO5024048 and ritonavir-boosted danoprevir with and without Copegus (Ribavirin) in interferon-naïve patients with chronic hepatitis C genotype 1 (INFORM-SVR). 2011. Available at. Accessed February 25, 2011.
-
A study on the combination of RO5024048 and ritonavir-boosted danoprevir with and without Copegus (Ribavirin) in interferon-naïve patients with chronic hepatitis C genotype 1 (INFORM-SVR). 2011. Available at: Accessed February 25, 2011. http://clinicaltrials.gov/ct2/show/NCT01278134.
-
-
-
-
41
-
-
77955873433
-
Phase 1b study of pegylated interferon λ 1 with or without ribavirin in patients with chronic genotype 1 hepatitis C virus infection
-
Muir A.J., Shiffman M.L., Zaman A., et al. Phase 1b study of pegylated interferon λ 1 with or without ribavirin in patients with chronic genotype 1 hepatitis C virus infection. Hepatology 2010, 52:822-832.
-
(2010)
Hepatology
, vol.52
, pp. 822-832
-
-
Muir, A.J.1
Shiffman, M.L.2
Zaman, A.3
-
42
-
-
66149129922
-
The cyclophilin inhibitor Debio 025 combined with PEG IFNα2a significantly reduces viral load in treatment-naive hepatitis C patients
-
Flisiak R., Feinman S.V., Jablkowski M., et al. The cyclophilin inhibitor Debio 025 combined with PEG IFNα2a significantly reduces viral load in treatment-naive hepatitis C patients. Hepatology 2009, 49:1460-1468.
-
(2009)
Hepatology
, vol.49
, pp. 1460-1468
-
-
Flisiak, R.1
Feinman, S.V.2
Jablkowski, M.3
-
43
-
-
67650567074
-
Efficacy and safety of the cyclophilin inhibitor DEBIO 025 in combination with pegylated interferon α 2a and ribavirin in previously null-responder genotype 1 HCV patients
-
Nelson D., Ghalib R., Sulkowski M., et al. Efficacy and safety of the cyclophilin inhibitor DEBIO 025 in combination with pegylated interferon α 2a and ribavirin in previously null-responder genotype 1 HCV patients. JHepatol 2010, 50(Suppl 1):S40.
-
(2010)
JHepatol
, vol.50
, Issue.SUPPL 1
-
-
Nelson, D.1
Ghalib, R.2
Sulkowski, M.3
-
44
-
-
67650559141
-
Safety, plasma pharmacokinetics and anti-viral activity of SCY-635 in adult patients with chronic hepatitis C virus infection
-
Hopkins S., Heuman D., Gavis E., et al. Safety, plasma pharmacokinetics and anti-viral activity of SCY-635 in adult patients with chronic hepatitis C virus infection. JHepatol 2009, 50(Suppl 1):S36.
-
(2009)
JHepatol
, vol.50
, Issue.SUPPL 1
-
-
Hopkins, S.1
Heuman, D.2
Gavis, E.3
-
45
-
-
80051935219
-
Short term safety, tolerability, pharmacokinetics and preliminary activity of GS-9450, a selective caspase inhibitor in patients with chronic HCV infection
-
Manns M., Lawitz E., Hoepelman A. Short term safety, tolerability, pharmacokinetics and preliminary activity of GS-9450, a selective caspase inhibitor in patients with chronic HCV infection. JHepatol 2010, 52(Suppl 1):S114-S115.
-
(2010)
JHepatol
, vol.52
, Issue.SUPPL 1
-
-
Manns, M.1
Lawitz, E.2
Hoepelman, A.3
-
46
-
-
84888053700
-
-
Available at:, Accessed February 25, 2011
-
Available at:, Accessed February 25, 2011. http://www.globeimmune.com/products/gi-5005/.
-
-
-
-
47
-
-
80051953573
-
GI-5005 therapeutic vaccine plus PEG-IFN/Ribavirin significantly improves virologic response and ALT normalization at end of treatment and improves SVR24 compared to PEG-IFN/Ribavirin in genotype 1 chronic HCV patients
-
Jacobson S., McHutchison J., Boyer T. GI-5005 therapeutic vaccine plus PEG-IFN/Ribavirin significantly improves virologic response and ALT normalization at end of treatment and improves SVR24 compared to PEG-IFN/Ribavirin in genotype 1 chronic HCV patients. JHepatol 2010, 52(Suppl 1):S465-S466.
-
(2010)
JHepatol
, vol.52
, Issue.SUPPL 1
-
-
Jacobson, S.1
McHutchison, J.2
Boyer, T.3
-
48
-
-
70349292099
-
Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance
-
Ge D., Fellay J., Thompson A., et al. Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance. Nature 2009, 461:399-401.
-
(2009)
Nature
, vol.461
, pp. 399-401
-
-
Ge, D.1
Fellay, J.2
Thompson, A.3
-
49
-
-
80051936839
-
GI-5005 therapeutic vaccine plus Peg-IFN/ribavirin improves sustained virological response versus Peg-IFN/Ribavirin in prior non-responders with genotype 1 chronic HCV infection
-
Pockros P., Jacobson I., Boyer T., et al. GI-5005 therapeutic vaccine plus Peg-IFN/ribavirin improves sustained virological response versus Peg-IFN/Ribavirin in prior non-responders with genotype 1 chronic HCV infection. Hepatology 2011, 52:404A.
-
(2011)
Hepatology
, vol.52
-
-
Pockros, P.1
Jacobson, I.2
Boyer, T.3
-
50
-
-
80051935018
-
GI-5005 therapeutic vaccine improves deficit in cellular immunity in IL28B Genotype T/T, treatment naive patients with Chronic hepatitis C genotype 1 when added to standard of care(SOC) PEG-IFN-α-2a/Ribavirin
-
Vierling J., McHutchison J., Jacobson I., et al. GI-5005 therapeutic vaccine improves deficit in cellular immunity in IL28B Genotype T/T, treatment naive patients with Chronic hepatitis C genotype 1 when added to standard of care(SOC) PEG-IFN-α-2a/Ribavirin. Hepatology 2011, 52:1258A.
-
(2011)
Hepatology
, vol.52
-
-
Vierling, J.1
McHutchison, J.2
Jacobson, I.3
-
51
-
-
84888030729
-
-
Available at:, Accessed February 25, 2011
-
Available at:, Accessed February 25, 2011. http://www.conatuspharma.com/products/cts-1027-for-liver-disease.htm.
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