Antibacterial properties of recombinant human non-pancreatic secretory phospholipase A2

Biochemical and Biophysical Research Communications

Volumn 441, Issue 2, 2013, Pages 453-456

  Qiu, Shunchen ^a   Lai, Luhua ^a,b  

^a PEKING UNIVERSITY   (China)

^b PEKING UNIVERSITY   (China)

Author keywords

Bactericidal activity; Gram negative bacteria; Gram positive bacteria; Human non pancreatic secretory phospholipase A2; pH

Indexed keywords

ARGININE; GLUTAMIC ACID; LYSINE; MUTANT PROTEIN; RECOMBINANT ENZYME; RECOMBINANT PHOSPHOLIPASE A2; UNCLASSIFIED DRUG;

ALKALINITY; ANTIBACTERIAL ACTIVITY; ARTICLE; BACTERIAL INFECTION; BACTERICIDAL ACTIVITY; BIOCOMPATIBILITY; ENZYME STABILITY; ESCHERICHIA COLI; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; INNATE IMMUNITY; NONHUMAN; PH; PRIORITY JOURNAL; STAPHYLOCOCCUS AUREUS;

BACTERICIDAL ACTIVITY; GRAM-NEGATIVE BACTERIA; GRAM-POSITIVE BACTERIA; HNPSPLA(2); HUMAN NON-PANCREATIC SECRETORY PHOSPHOLIPASE A(2); PH; PHOSPHOLIPASE A(2); PLA(2); SECRETORY PHOSPHOLIPASE A(2); SPLA(2);

ANTI-BACTERIAL AGENTS; ESCHERICHIA COLI; GROUP II PHOSPHOLIPASES A2; HUMANS; MUTATION; RECOMBINANT PROTEINS; STAPHYLOCOCCUS AUREUS;

ESCHERICHIA COLI; NEGIBACTERIA; POSIBACTERIA;

EID: 84888013697     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2013.10.092     Document Type: Article

References (17)

1. J.E. Burke, and E.A. Dennis Phospholipase A2 biochemistry Cardiovasc. Drugs Ther. 23 2009 49 59
2. S. Yedgar, D. Lichtenberg, and E. Schnitzer Inhibition of phospholipase A(2) as a therapeutic target Biochim. Biophys. Acta 1488 2000 182 187
3. A. Huwiler, G. Staudt, R.M. Kramer, and J. Pfeilschifter Cross-talk between secretory phospholipase A2 and cytosolic phospholipase A2 in rat renal mesangial cells Biochim. Biophys. Acta 1348 1997 257 272
4. M. Murakami, Y. Taketomi, Y. Miki, H. Sato, T. Hirabayashi, and K. Yamamoto Recent progress in phospholipase A(2) research: from cells to animals to humans Prog. Lipid Res. 50 2011 152 192
5. S.A. Beers, A.G. Buckland, R.S. Koduri, W. Cho, M.H. Gelb, and D.C. Wilton The antibacterial properties of secreted phospholipases A2: a major physiological role for the group IIA enzyme that depends on the very high pI of the enzyme to allow penetration of the bacterial cell wall J. Biol. Chem. 277 2002 1788 1793
6. A.G. Buckland, and D.C. Wilton The antibacterial properties of secreted phospholipases A(2) Biochim. Biophys. Acta, Mol. Cell Biol. Lipids 1488 2000 71 82
7. Y. Weinrauch, C. Abad, P. Elsbach, S. Lowry, and J. Weiss Mobilization of potent plasma (serum) bactericidal activity toward Gram-positive bacteria during systemic bacterial challenge: role of group II phospholipase A2 (PLA2) J. Invest. Med. 44 1996 A268
8. Y. Weinrauch, P. Elsbach, L.M. Madsen, A. Foreman, and J. Weiss The potent anti-Staphylococcus aureus activity of a sterile rabbit inflammatory fluid is due to a 14-kD phospholipase A2 J. Clin. Invest. 97 1996 250 257
9. X.D. Qu, and R.I. Lehrer Secretory phospholipase A2 is the principal bactericide for staphylococci and other gram-positive bacteria in human tears Infect. Immun. 66 1998 2791 2797
10. P. Elsbach, J. Weiss, R.C. Franson, S. Beckerdite-Quagliata, A. Schneider, and L. Harris Separation and purification of a potent bactericidal/permeability-increasing protein and a closely associated phospholipase A2 from rabbit polymorphonuclear leukocytes. Observations on their relationship J. Biol. Chem. 254 1979 11000 11009
11. S.S. Harwig, L. Tan, X.D. Qu, Y. Cho, P.B. Eisenhauer, and R.I. Lehrer Bactericidal properties of murine intestinal phospholipase A2 J. Clin. Invest. 95 1995 603 610
12. J. Weiss, M. Inada, P. Elsbach, and R.M. Crowl Structural determinants of the action against Escherichia coli of a human inflammatory fluid phospholipase A2 in concert with polymorphonuclear leukocytes J. Biol. Chem. 269 1994 26331 26337
13. A.P. Gimenez, Y.Z. Wu, M. Paya, C. Delclaux, L. Touqui, and P.L. Goossens High bactericidal efficiency of type IIA phospholipase A(2) against Bacillus anthracis and inhibition of its secretion by the lethal toxin J. Immunol. 173 2004 521 530
14. A.K. Foreman-Wykert, Y. Weinrauch, P. Elsbach, and J. Weiss Cell-wall determinants of the bactericidal action of group IIA phospholipase A(2) against Gram-positive bacteria J. Clin. Invest. 103 1999 715 721
15. J.O. Gronroos, V.J. Laine, M.J. Janssen, M.R. Egmond, and T.J. Nevalainen Bactericidal properties of group IIA and group V phospholipases A2 J. Immunol. 166 2001 4029 4034
16. S. Qiu, and L. Lai Tailoring the pH dependence of human non-pancreatic secretory phospholipase A by engineering surface charges Appl. Biochem. Biotechnol. 2013 10.1007/s12010-013-0437-2
17. C. Huang, L. Zhou, Y. Liu, and L. Lai A continuous fluorescence assay for phospholipase A2 with nontagged lipid Anal. Biochem. 351 2006 11 17