Using conditioned place preference to identify relapse prevention medications

Neuroscience and Biobehavioral Reviews

Volumn 37, Issue 9, 2013, Pages 2081-2086

  Napier, T Celeste ^a   Herrold, Amy A ^b   De Wit, Harriet ^c  

^a RUSH UNIVERSITY   (United States)

^b HINES VA HOSPITAL   (United States)

^c UNIVERSITY OF CHICAGO   (United States)

Author keywords

Addiction therapy; Amphetamine; Baclofen; Conditioned place preference; Humans; Methamphetamine; Mirtazapine; Naltrexone; Rodents; Varenicline

Indexed keywords

BACLOFEN; MIRTAZAPINE; NALTREXONE; UNCLASSIFIED DRUG; VARENICLINE; VIVATROL;

ALCOHOLISM; DRUG ABUSE; DRUG DEPENDENCE; DRUG DEVELOPMENT; DRUG EFFECT; DRUG SEEKING BEHAVIOR; DRUG WITHDRAWAL; HUMAN; MOTIVATION; NONHUMAN; OPIATE ADDICTION; PLACE PREFERENCE; PRIORITY JOURNAL; RELAPSE; REVIEW; RODENT; SPASTICITY;

ADDICTION THERAPY; AMPHETAMINE; BACLOFEN; CONDITIONED PLACE PREFERENCE; HUMANS; METHAMPHETAMINE; MIRTAZAPINE; NALTREXONE; RODENTS; VARENICLINE;

ANIMALS; ANTIDEPRESSIVE AGENTS, TRICYCLIC; BEHAVIOR, ANIMAL; CENTRAL NERVOUS SYSTEM STIMULANTS; CONDITIONING (PSYCHOLOGY); HUMANS; MOTIVATION; RECURRENCE;

EID: 84888012166     PISSN: 01497634     EISSN: 18737528     Source Type: Journal    
DOI: 10.1016/j.neubiorev.2013.05.002     Document Type: Review

References (74)

1. Addolorato G., Leggio L., Ferrulli A., Cardone S., Bedogni G., Caputo F., Gasbarrini G., Landolfi R. Dose-response effect of baclofen in reducing daily alcohol intake in alcohol dependence: secondary analysis of a randomized, double-blind, placebo-controlled trial. Alcohol Alcohol 2011, 46:312-317.
2. Afshar M., Knapp C.M., Sarid-Segal O., Devine E., Colaneri L.S., Tozier L., Waters M.E., Putnam M.A., Ciraulo D.A. The efficacy of mirtazapine in the treatment of cocaine dependence with comorbid depression. Am. J. Drug Alcohol Abuse 2012, 38:181-186.
3. Altintoprak A.E., Zorlu N., Coskunol H., Akdeniz F., Kitapcioglu G. Effectiveness and tolerability of mirtazapine and amitriptyline in alcoholic patients with co-morbid depressive disorder: a randomized, double-blind study. Hum. Psychopharmacol. 2008, 23:313-319.
4. Assadi S.M., Radgoodarzi R., Ahmadi-Abhari S.A. Baclofen for maintenance treatment of opioid dependence: a randomized double-blind placebo-controlled clinical trial [ISRCTN32121581]. BMC Psychiatry 2003, 3:16.
5. Bardo M.T., Bevins R.A. Conditioned place preference: what does it add to our preclinical understanding of drug reward?. Psychopharmacology (Berl) 2000, 153:31-43.
6. Biala G., Staniak N., Budzynska B. Effects of varenicline and mecamylamine on the acquisition, expression, and reinstatement of nicotine-conditioned place preference by drug priming in rats. Naunyn. Schmiedebergs Arch. Pharmacol. 2010, 381:361-370.
7. Bouton M.E. Context, ambiguity, and unlearning: sources of relapse after behavioral extinction. Biol. Psychiatry 2002, 52:976-986.
8. Brandon T.H., Drobes D.J., Unrod M., Heckman B.W., Oliver J.A., Roetzheim R.C., Karver S.B., Small B.J. Varenicline effects on craving, cue reactivity and smoking reward. Psychopharmacology (Berl) 2011, 218:391-403.
9. Carter L.P., Griffiths R.R. Principles of laboratory assessment of drug abuse liability and implications for clinical development. Drug Alcohol Depend. 2009, 105(Suppl. 1):S14-S25.
10. Chaudhri N., Sahuque L.L., Schairer W.W., Janak P.H. Separable roles of the nucleus accumbens core and shell in context- and cue-induced alcohol-seeking. Neuropsychopharmacology 2010, 35:783-791.
11. Childs E., de Wit H. Amphetamine-induced place preference in humans. Biol. Psychiatry 2009, 65:900-904.
12. Childs E., de Wit H. Contextual conditioning enhances the psychostimulant and incentive properties of d-amphetamine in humans. Addict. Biol. 2011, November 29. [Epub ahead of print]. 10.1111/j.1369-1600.2011.00416.x.
13. Childs E., de Wit H. Alcohol-induced conditioned place preference in moderate drinkers. Presented at the 2012 Meeting of the American College of Neuropsychopharmacology 2012.
14. Colfax G.N., Santos G.M., Das M., Santos D.M., Matheson T., Gasper J., Shoptaw S., Vittinghoff E. Mirtazapine to reduce methamphetamine use: a randomized controlled trial. Arch. Gen. Psychiatry 2011, 68:1168-1175.
15. Crombag H.S., Bossert J.M., Koya E., Shaham Y. Context-induced relapse to drug seeking: a review. Philos. Trans. R. Soc. Lond. B: Biol. Sci. 2008, 363:3233-3243.
16. Cunningham C.L., Ferree N.K., Howard M.A. Apparatus bias and place conditioning with ethanol in mice. Psychopharmacology (Berl) 2003, 170:409-422.
17. Cunningham C.L., Niehus J.S., Noble D. Species difference in sensitivity to ethanol's hedonic effects. Alcohol 1993, 10:97-102.
18. de Wit H., Stewart J. Reinstatement of cocaine-reinforced responding in the rat. Psychopharmacology (Berl) 1981, 75:134.
19. Fattore L., Spano M.S., Cossu G., Scherma M., Fratta W., Fadda P. Baclofen prevents drug-induced reinstatement of extinguished nicotine-seeking behaviour and nicotine place preference in rodents. Eur. Neuropsychopharmacol. 2009, 19:487-498.
20. Flagel S.B., Akil H., Robinson T.E. Individual differences in the attribution of incentive salience to reward-related cues: implications for addiction. Neuropharmacology 2009, 56(Suppl. 1):139L 148.
21. Fox H.C., Anderson G.M., Tuit K., Hansen J., Kimmerling A., Siedlarz K.M., Morgan P.T., Sinha R. Prazosin effects on stress- and cue-induced craving and stress response in alcohol-dependent individuals: preliminary findings. Alcohol Clin Exp Res 2012, 36:351-360.
22. Franklin T., Wang Z., Suh J.J., Hazan R., Cruz J., Li Y., Goldman M., Detre J.A., O'Brien C.P., Childress A.R. Effects of varenicline on smoking cue-triggered neural and craving responses. Arch. Gen. Psychiatry 2011, 68:516-526.
23. Fricks-Gleason A.N., Marshall J.F. Post-retrieval beta-adrenergic receptor blockade: effects on extinction and reconsolidation of cocaine-cue memories. Learn. Mem. 2008, 15:643-648.
24. From A., Heltberg A. A double-blind trial with baclofen (Lioresal) and diazepam in spasticity due to multiple sclerosis. Acta Neurol. Scand. 1975, 51:158-166.
25. Gass J.T., Olive M.F. Positive allosteric modulation of mGluR5 receptors facilitates extinction of a cocaine contextual memory. Biol. Psychiatry 2009, 65:717-720.
26. Gerra G., Zaimovic A., Rustichelli P., Fontanesi B., Zambelli U., Timpano M., Bocchi C., Delsignore R. Rapid opiate detoxication in outpatient treatment: relationship with naltrexone compliance. J. Subst. Abuse Treat. 2000, 18:185-191.
27. Graves S.M., Napier T.C. Mirtazapine alters cue-associated methamphetamine seeking in rats. Biol. Psychiatry 2011, 69:275-281.
28. Graves S.M., Persons A.L., Riddle J.L., Napier T.C. The atypical antidepressant mirtazapine attenuates expression of morphine-induced place preference and motor sensitization. Brain Res. 2012, 1472:45-53.
29. Graves S.M., Rafeyan R., Watts J., Napier T.C. Mirtazapine, and mirtazapine-like compounds as possible pharmacotherapy for substance abuse disorders: evidence from the bench and the bedside. Pharmacol. Ther. 2012, 136:343-353.
30. Heinrichs S.C., Leite-Morris K.A., Carey R.J., Kaplan G.B. Baclofen enhances extinction of opiate conditioned place preference. Behav. Brain Res. 2010, 207:353-359.
31. Herrold A.A., Shen F., Graham M.P., Harper L.K., Specio S.E., Tedford C.E., Napier T.C. Mirtazapine treatment after conditioning with methamphetamine alters subsequent expression of place preference. Drug Alcohol Depend. 2009, 99:231-239.
32. Herrold A.A., Voigt R.M., Napier T.C. mGluR5 is necessary for maintenance of methamphetamine-induced associative learning. Eur. Neuropsychopharmacol. 2012, (in press).
33. Herzig V., Capuani E.M., Kovar K.A., Schmidt W.J. Effects of MPEP on expression of food-, MDMA- or amphetamine-conditioned place preference in rats. Addict. Biol. 2005, 10:243-249.
34. Herzig V., Schmidt W.J. Effects of MPEP on locomotion, sensitization aond conditionined reward induced by cocaine or morphine. Neuropharmacology 2004, 47:973-984.
35. Hogarth L., Dickinson A., Duka T. The associative basis of cue-elicited drug taking in humans. Psychopharmacology (Berl) 2010, 208:337-351.
36. Itzhak Y., Roger-Sanchez C., Kelley J.B., Anderson K.L. Discrimination between cocaine-associated context and cue in a modified conditioned place preference paradigm: role of the nNOS gene in cue conditioning. Int. J. Neuropsychopharmacol. 2010, 13:171-180.
37. Kang L., Wang D., Li B., Hu M., Zhang P., Li J. Mirtazapine, a noradrenergic and specific serotonergic antidepressant, attenuates morphine dependence and withdrawal in Sprague-Dawley rats. Am. J. Drug Alcohol Abuse 2008, 34:541-552.
38. Kuzmin A., Sandin J., Terenius L., Ogren S.O. Acquisition, expression, and reinstatement of ethanol-induced conditioned place preference in mice: effects of opioid receptor-like 1 receptor agonists and naloxone. J. Pharmacol. Exp. Ther. 2003, 304:310-318.
39. Langleben D.D., Ruparel K., Elman I., Loughead J.W., Busch E.L., Cornish J., Lynch K.G., Nuwayser E.S., Childress A.R., O'Brien C.P. Extended-release naltrexone modulates brain response to drug cues in abstinent heroin-dependent patients. Addict. Biol. 2012, (in press).
40. Ludwig A.M. Pavlov's bells and alcohol craving. Addict. Behav. 1986, 11:87-91.
41. McDaid J., Tedford C.E., Mackie A.R., Dallimore J.E., Mickiewicz A.L., Shen F., Angle J.M., Napier T.C. Nullifying drug-induced sensitization: behavioral and electrophysiological evaluations of dopaminergic and serotonergic ligands in methamphetamine-sensitized rats. Drug Alcohol Depend. 2007, 86:55-66.
42. Middaugh L.D., Bandy A.L. Naltrexone effects on ethanol consumption and response to ethanol conditioned cues in C57BL/6 mice. Psychopharmacology (Berl) 2000, 151:321-327.
43. 3 receptor antagonism on approach responses to food cues in overweight and obese individuals. Behav. Pharmacol. 2012, 23:603-608.
44. Mucha R.F., Pauli P., Angrilli A. Conditioned responses elicited by experimentally produced cues for smoking. Can. J. Physiol. Pharmacol. 1998, 76:259-268.
45. Mueller D., Perdikaris D., Stewart J. Persistence and drug-induced reinstatement of a morphine-induced conditioned place preference. Behav. Brain Res. 2002, 136:389-397.
46. O'Brien C.P., Childress A.R., McLellan A.T., Ehrman R. Classical conditioning in drug-dependent humans. Ann. N. Y. Acad. Sci. 1992, 654:400-415.
47. O'Malley S.S., Krishnan-Sarin S., McKee S.A., Leeman R.F., Cooney N.L., Meandzija B., Wu R., Makuch R.W. Dose-dependent reduction of hazardous alcohol use in a placebo-controlled trial of naltrexone for smoking cessation. Int. J. Neuropsychopharmacol. 2009, 12:589-597.
48. Ostlund S.B., Balleine B.W. On habits and addiction: an associative analysis of compulsive drug seeking. Drug Discov. Today Dis. Models 2008, 5:235-245.
49. Otis J.M., Mueller D. Inhibition of β-adrenergic receptors induces a persistent deficit in retrieval of a cocaine-associated memory providing protection against reinstatement. Neuropsychopharmacology 2011, 36:1912-1920.
50. Panlilio L.V., Yasar S., Nemeth-Coslett R., Katz J.L., Henningfield J.E., Solinas M., Heishman S.J., Schindler C.W., Goldberg S.R. Human cocaine-seeking behavior and its control by drug-associated stimuli in the laboratory. Neuropsychopharmacology 2005, 30:433-443.
51. Pavlov I.P. Conditioned Reflexes. An Investigation of the Physiological Activity of the Cerebral Cortex 1927, Oxford University Press, Oxford, UK.
52. Robinson T.E., Berridge K.C. The neural basis of drug craving: an incentive-sensitization theory of addiction. Brain Res. Rev. 1993, 18:247-291.
53. Rollema H., Chambers L.K., Coe J.W., Glowa J., Hurst R.S., Lebel L.A., Lu Y., Mansbach R.S., Mather R.J., Rovetti C.C., Sands S.B., Schaeffer E., Schulz D.W., Tingley F.D., Williams K.E. Pharmacological profile of the alpha4beta2 nicotinic acetylcholine receptor partial agonist varenicline, an effective smoking cessation aid. Neuropharmacology 2007, 52:985-994.
54. Sawa G.M., Paty D.W. The use of baclofen in treatment of spasticity in multiple sclerosis. Can. J. Neurol. Sci. 1979, 6:351-354.
55. Shen F., Meredith G.E., Napier T.C. Amphetamine-induced place preference and conditioned motor sensitization requires activation of tyrosine kinase receptors in the hippocampus. J. Neurosci. 2006, 26:11041-11051.
56. Spyraki C., Kazandjian A., Varonos D. Diazepam-induced place preference conditioning: appetitive and antiaversive properties. Psychopharmacology (Berl) 1985, 87:225-232.
57. Stempien L., Tsai T. Intrathecal baclofen pump use for spasticity: a clinical survey. Am. J. Phys. Med. Rehabil. 2000, 79:536-541.
58. Stephens D.N., Crombag H.S., Duka T. The challenge of studying parallel behaviors in humans and animal models. Curr. Topics Behav. Neurosci. 2013, 13:611-645.
59. Stephens D.N., Duka T., Crombag H.S., Cunningham C.L., Heilig M., Crabbe J.C. Reward sensitivity: issues of measurement, and achieving consilience between human and animal phenotypes. Addict. Biol. 2010, 15:145-168.
60. Stewart J. Conditioned and unconditioned drug effects in relapse to opiate and stimulant drug self-adminstration. Prog. Neuropsychopharmacol. Biol. Psychiatry 1983, 7:591-597.
61. Stewart J., de Wit H., Eikelboom R. Role of unconditioned and contitioned drug effects in the self-administration of opiates and stimulants. Psychol. Rev. 1984, 91:251-268.
62. Tolliver B.K., McRae-Clark A.L., Saladin M., Price K.L., Simpson A.N., Desantis S.M., Baker N.L., Brady K.T. Determinants of cue-elicited craving and physiologic reactivity in methamphetamine-dependent subjects in the laboratory. Am. J. Drug Alcohol Abuse 2010, 36:106-113.
63. Tzschentke T.M. Measuring reward with the conditioned place preference paradigm: a comprehensive review of drug effects, recent progress and new issues. Prog. Neurobiol. 1998, 56:613-672.
64. Tzschentke T.M. Measuring reward with the conditioned place preference (CPP) paradigm: update of the last decade. Addict. Biol. 2007, 12:227-462.
65. Vezina P., Stewart J. Conditioned locomotion and place preference elicited by tactile cues paired exclusively with morphine in an open field. Psychopharmacology (Berl) 1987, 91:375-380.
66. Vidal-Infer A., Roger-Sanchez C., Daza-Losada M., Aguilar M.A., Minarro J., Rodriguez M. Role of the dopaminergic system in the acquisition, expression and reinstatement of MDMA-induced conditioned place preference in adolescent mice. PLoS ONE 2012, 7:e43107.
67. Voigt R.M., Herrold A.A., Napier T.C. Baclofen facilitates the extinction of methamphetamine-induced conditioned place preference in rats. Behav. Neurosci. 2011, 125:261-267.
68. Voigt R.M., Herrold A.A., Riddle J.L., Napier T.C. Administration of GABA(B) receptor positive allosteric modulators inhibit the expression of previously established methamphetamine-induced conditioned place preference. Behav. Brain Res. 2011, 216:419-423.
69. Voigt R.M., Mickiewicz A.L., Napier T.C. Repeated mirtazapine nullifies the maintenance of previously established methamphetamine-induced conditioned place preference in rats. Behav. Brain Res. 2011, 225:91-96.
70. Voigt R.M., Napier T.C. Context-dependent effects of a single administration of mirtazapine on the expression of methamphetamine-induced conditioned place preference. Front. Behav. Neurosci. 2011, 5:92.
71. Volpicelli J.R. Alcohol abuse and alcoholism: an overview. J. Clin. Psychiatry 2001, 62(Suppl. 20):4-10.
72. Wikler A. Dynamics of drug dependence. Implications of a conditioning theory for research and treatment. Arch. Gen. Psychiatry 1973, 28:611-616.
73. Ye X.F., Lu Y., Zhang P., Liang J.H. Calmodulin inhibitor trifluoperazine attenuates the developemnt and expression of morphine-induced conditioned place preference in rats. Eur. J. Pharmacol. 2004, 486:265-271.
74. Yoon S.J., Pae C.U., Kim D.J., Namkoong K., Lee E., Oh D.Y., Lee Y.S., Shin D.H., Jeong Y.C., Kim J.H., Choi S.B., Hwang I.B., Shin Y.C., Cho S.N., Lee H.K., Lee C.T. Mirtazapine for patiens with alcohol dependence and comorbid depressive disorders: a multicentre, open label study. Prog. Neuropsychopharmacol. Biol. Psychiatry 2006, 30:1196-1201.