-
1
-
-
36049006592
-
Immunogenicity of protein therapeutics
-
De Groot AS, Scott DW. Immunogenicity of protein therapeutics. Trends Immunol. 28(11), 482-490 (2007
-
(2007)
Trends Immunol
, vol.28
, Issue.11
, pp. 482-490
-
-
De Groot, A.S.1
Scott, D.W.2
-
2
-
-
54049088585
-
Activation of natural regulatory t cells by igg fc-derived peptide "tregitopes
-
De Groot AS, Moise L, McMurry JA et al. Activation of natural regulatory T cells by IgG Fc-derived peptide "Tregitopes." Blood 112(8), 3303-3311 (2008
-
(2008)
Blood
, vol.112
, Issue.8
, pp. 3303-3311
-
-
De Groot, A.S.1
Moise, L.2
McMurry, J.A.3
-
3
-
-
63749128279
-
Reducing risk, improving outcomes: Bioengineering less immunogenic protein therapeutics
-
De Groot AS, Martin W. Reducing risk, improving outcomes: Bioengineering less immunogenic protein therapeutics. Clin. Immunol. 131(2), 189-201 (2009
-
(2009)
Clin. Immunol
, vol.131
, Issue.2
, pp. 189-201
-
-
De Groot, A.S.1
Martin, W.2
-
4
-
-
84888022850
-
T-cell dependent immunogenicity of protein therapeutics: Preclinical assessment and mitigation
-
In Press
-
Cousens LP, Jawa V, Awwad M, Wakshull E, Kropshofer H, De Groot AS. T-cell dependent immunogenicity of protein therapeutics: Preclinical assessment and mitigation. Clin. Immunol. (2013) (In Press
-
(2013)
Clin. Immunol
-
-
Cousens, L.P.1
Jawa, V.2
Awwad, M.3
Wakshull, E.4
Kropshofer, H.5
De Groot, A.S.6
-
5
-
-
84887283047
-
Beyond humanization and deimmunization: Tolerization as a method for reducing the immunogenicity of biologics
-
In Press
-
De Groot AS, Terry F, Cousens LP, Martin W. Beyond Humanization and Deimmunization: Tolerization as a method for reducing the immunogenicity of biologics. Exp. Rev. Clin. Pharmacol. (2013) (In Press
-
(2013)
Exp. Rev. Clin. Pharmacol
-
-
De Groot, A.S.1
Terry, F.2
Cousens, L.P.3
Martin, W.4
-
6
-
-
84872403415
-
Tregitope update: Mechanism of action parallels IVIg
-
Cousens LP, Tassone R, Mazer BD, Ramachandiran V, Scott DW, De Groot AS. Tregitope update: Mechanism of action parallels IVIg. Autoimmun. Rev. 12(3), 436-443 (2012
-
(2012)
Autoimmun. Rev
, vol.12
, Issue.3
, pp. 436-443
-
-
Cousens, L.P.1
Tassone, R.2
Mazer, B.D.3
Ramachandiran, V.4
Scott, D.W.5
De Groot, A.S.6
-
7
-
-
79958264390
-
Vaccination with patient-specific tumorderived antigen in first remission improves disease-free survival in follicular lymphoma
-
Schuster SJ, Neelapu SS, Gause BL et al. Vaccination with patient-specific tumorderived antigen in first remission improves disease-free survival in follicular lymphoma. J. Clin. Oncol. 29(20), 2787-2794 (2011
-
(2011)
J. Clin. Oncol
, vol.29
, Issue.20
, pp. 2787-2794
-
-
Schuster, S.J.1
Neelapu, S.S.2
Gause, B.L.3
-
8
-
-
38349191376
-
Expansion of CD4+CD25+ regulatory T cells by intravenous immunoglobulin: A critical factor in controlling experimental autoimmune encephalomyelitis
-
Ephrem A, Chamat S, Miquel C et al. Expansion of CD4+CD25+ regulatory T cells by intravenous immunoglobulin: A critical factor in controlling experimental autoimmune encephalomyelitis. Blood 111(2), 715-722 (2008
-
(2008)
Blood
, vol.111
, Issue.2
, pp. 715-722
-
-
Ephrem, A.1
Chamat, S.2
Miquel, C.3
-
9
-
-
84860751767
-
High-dose intravenous immunoglobulin treatment increases regulatory T cells in patients with eosinophilic granulomatosis with polyangiitis
-
Tsurikisawa N, Saito H, Oshikata C, Tsuburai T, Akiyama K. High-dose intravenous immunoglobulin treatment increases regulatory T cells in patients with eosinophilic granulomatosis with polyangiitis. J. Rheumatol. 39(5), 1019-1025 (2012
-
(2012)
J. Rheumatol
, vol.39
, Issue.5
, pp. 1019-1025
-
-
Tsurikisawa, N.1
Saito, H.2
Oshikata, C.3
Tsuburai, T.4
Akiyama, K.5
-
10
-
-
84875410765
-
Nimmerjahn F Intravenous immunoglobulin therapy: How does IgG modulate the immune system?
-
Schwab I, Nimmerjahn F Intravenous immunoglobulin therapy: How does IgG modulate the immune system? Nat. Rev. Immunol. 13(3), 176-189 (2013
-
(2013)
Nat. Rev. Immunol
, vol.13
, Issue.3
, pp. 176-189
-
-
Schwab, I.1
-
11
-
-
33747842285
-
Treatment of diabetes in NOD mice by gene transfer of Ig-fusion proteins into B cells: Role of T regulatory cells
-
Soukhareva N, Jiang Y, Scott DW. Treatment of diabetes in NOD mice by gene transfer of Ig-fusion proteins into B cells: Role of T regulatory cells. Cell Immunol. 240, 41-46 (2006
-
(2006)
Cell Immunol
, vol.240
, pp. 41-46
-
-
Soukhareva, N.1
Jiang, Y.2
Scott, D.W.3
-
12
-
-
21044442418
-
IVIg therapy in autoimmunity and related disorders: Our experience with a large cohort of patients
-
Shoenfeld Y, Katz U. IVIg therapy in autoimmunity and related disorders: Our experience with a large cohort of patients. Autoimmunity 38(2):123-137 (2005
-
(2005)
Autoimmunity
, vol.38
, Issue.2
, pp. 123-137
-
-
Shoenfeld, Y.1
Katz, U.2
-
13
-
-
79957508762
-
Regulation of immunity and inflammation by intravenous immunoglobulin: Relevance to solid organ transplantation
-
Jordan SC, Toyoda, M, Vo AA. Regulation of immunity and inflammation by intravenous immunoglobulin: Relevance to solid organ transplantation. Expert Rev. Clin. Immunol. 7(3), 341-348 (2011
-
(2011)
Expert Rev. Clin. Immunol
, vol.7
, Issue.3
, pp. 341-348
-
-
Jordan, S.C.1
Toyoda, M.2
Vo, A.A.3
-
14
-
-
84862868292
-
Long-term therapy with intravenous immunoglobulin is beneficial in patients with autoimmune diseases
-
Zandman-Goddard G, Krauthammer A, Levy Y, Langevitz P, Shoenfeld Y. Long-Term Therapy with Intravenous Immunoglobulin is Beneficial in Patients with Autoimmune Diseases. Clin. Rev. Allergy Immunol. 42(2), 247-255 (2012
-
(2012)
Clin. Rev. Allergy Immunol
, vol.42
, Issue.2
, pp. 247-255
-
-
Zandman-Goddard, G.1
Krauthammer, A.2
Levy, Y.3
Langevitz, P.4
Shoenfeld, Y.5
-
15
-
-
68949177252
-
Intravenous immunoglobulins in systemic lupus erythematosus: From the bench to the bedside
-
Zandman-Goddard G, Blank M, Shoenfeld Y. Intravenous immunoglobulins in systemic lupus erythematosus: From the bench to the bedside. Lupus 18(10), 884-888 (2009
-
(2009)
Lupus
, vol.18
, Issue.10
, pp. 884-888
-
-
Zandman-Goddard, G.1
Blank, M.2
Shoenfeld, Y.3
-
16
-
-
0035084797
-
Combined prednisolone and intravenous immunoglobulin treatment for acquired factor VIII inhibitors: A 2-year review
-
Dykes AC, Walker ID, Lowe GD, Tait RC. Combined prednisolone and intravenous immunoglobulin treatment for acquired factor VIII inhibitors: A 2-year review. Haemophilia 7(2), 160-163 (2001
-
(2001)
Haemophilia
, vol.7
, Issue.2
, pp. 160-163
-
-
Dykes, A.C.1
Walker, I.D.2
Lowe, G.D.3
Tait, R.C.4
-
17
-
-
60549085053
-
Pathobiology of secondary immune thrombocytopenia
-
Cines DB, Liebman H, Stasi R. Pathobiology of secondary immune thrombocytopenia. Semin. Hematol. 46(1Suppl. 2), S2-S14 (2009
-
(2009)
Semin. Hematol
, vol.46
, Issue.1 SUPPL. 2
-
-
Cines, D.B.1
Liebman, H.2
Stasi, R.3
-
18
-
-
80054763479
-
Advances in the treatment of chronic inflammatory demyelinating neuropathies in 2010
-
Lozeron P, Adams D. Advances in the treatment of chronic inflammatory demyelinating neuropathies in 2010. J. Neurol. 258(9), 1737-1741 (2011
-
(2011)
J. Neurol
, vol.258
, Issue.9
, pp. 1737-1741
-
-
Lozeron, P.1
Adams, D.2
-
19
-
-
77951148910
-
Overview of the pathogenesis and treatment of chronic inflammatory demyelinating polyneuropathy with intravenous immunoglobulins
-
Rajabally YA, Mahdi-Rogers M. Overview of the pathogenesis and treatment of chronic inflammatory demyelinating polyneuropathy with intravenous immunoglobulins. Biologics 4, 45-49 (2010
-
(2010)
Biologics
, vol.4
, pp. 45-49
-
-
Rajabally, Y.A.1
Mahdi-Rogers, M.2
-
20
-
-
84872616027
-
In vitro and in vivo studies of igg-derived treg epitopes (tregitopes): A promising new tool for tolerance induction and treatment of autoimmunity
-
Cousens LP, Najafian N, Mingozzi F et al. In vitro and in vivo studies of IgG-derived Treg epitopes (Tregitopes): A promising new tool for tolerance induction and treatment of autoimmunity. J. Clin. Immunol. 33(1), 43-49 (2013
-
(2013)
J. Clin. Immunol
, vol.33
, Issue.1
, pp. 43-49
-
-
Cousens, L.P.1
Najafian, N.2
Mingozzi, F.3
-
21
-
-
84878135799
-
Application of IgG-derived natural treg epitopes (igg tregitopes) to antigen-specific tolerance induction in a murine model of type 1 diabetes
-
Cousens LP, Su Y, McClaine E et al. Application of IgG-derived natural Treg epitopes (IgG Tregitopes) to antigen-specific tolerance induction in a murine model of type 1 diabetes. J. Diabetes Res. 2013, 621693 (2013
-
(2013)
J. Diabetes Res
, vol.2013
, pp. 621693
-
-
Cousens, L.P.1
Su, Y.2
McClaine, E.3
-
22
-
-
84880992500
-
Regulatory T cell epitopes (tregitopes) in igg induce tolerance in vivo and lack immunogenicityper se
-
Su Y, Rossi R, De Groot AS, Scott DW. Regulatory T cell epitopes (Tregitopes) in IgG induce tolerance in vivo and lack immunogenicityper se. J. Leukoc. Biol. 94(2), 377-383 (2013
-
(2013)
J. Leukoc. Biol
, vol.94
, Issue.2
, pp. 377-383
-
-
Su, Y.1
Rossi, R.2
De Groot, A.S.3
Scott, D.W.4
-
23
-
-
84883741462
-
Modulation of CD8+ T cell responses to AAV vectors with IgG-derived MHC class II epitopes
-
Hui DJ, Basner-Tschakarjan E, Chen Y et al. Modulation of CD8+ T cell responses to AAV vectors with IgG-derived MHC class II epitopes. Mol Ther. 21(9), 1727-1737 (2013
-
(2013)
Mol Ther
, vol.21
, Issue.9
, pp. 1727-1737
-
-
Hui, D.J.1
Basner-Tschakarjan, E.2
Chen, Y.3
-
24
-
-
84868281890
-
Teaching tolerance: New approaches to enzyme replacement therapy for pompe disease
-
Cousens LP, Mingozzi F, Van Der Marel S et al. Teaching tolerance: New approaches to enzyme replacement therapy for Pompe disease. Hum. Vaccin. Immunother. 8(10), 1459-1464 (2012
-
(2012)
Hum. Vaccin. Immunother
, vol.8
, Issue.10
, pp. 1459-1464
-
-
Cousens, L.P.1
Mingozzi, F.2
Van Der Marel, S.3
-
25
-
-
84880911013
-
The two-faced T cell epitope: Examining the host-microbe interface with janus matrix
-
Moise L, Gutierrez AH, Bailey-Kellogg C et al. The two-faced T cell epitope: Examining the host-microbe interface with JanusMatrix. Hum. Vaccin. Immunother. 9(7), 1577-1586 (2013
-
(2013)
Hum. Vaccin. Immunother
, vol.9
, Issue.7
, pp. 1577-1586
-
-
Moise, L.1
Gutierrez, A.H.2
Bailey-Kellogg, C.3
-
26
-
-
28244494166
-
Tolerogenic treatment of lupus mice with consensus peptide induces Foxp3-expressing, apoptosis-resistant, TGFbeta-secreting CD8+ T cell suppressors
-
Hahn BH, Singh RP, La Cava A, Ebling FM. Tolerogenic treatment of lupus mice with consensus peptide induces Foxp3-expressing, apoptosis-resistant, TGFbeta-secreting CD8+ T cell suppressors. J. Immunol. 175(11), 7728-7737 (2005
-
(2005)
J. Immunol
, vol.175
, Issue.11
, pp. 7728-7737
-
-
Hahn, B.H.1
Singh, R.P.2
La Cava, A.3
Ebling, F.M.4
-
27
-
-
33745019520
-
A peptide based on the complementarity-determining region 1 of an autoantibody ameliorates lupus by up-regulating CD4+CD25+ cells and TGF-beta
-
Sharabi A, Zinger H, Zborowsky M, Sthoeger ZM, Mozes E. A peptide based on the complementarity-determining region 1 of an autoantibody ameliorates lupus by up-regulating CD4+CD25+ cells and TGF-beta. Proc. Natl Acad. Sci. USA 103(23), 8810-8815 (2006
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, Issue.23
, pp. 8810-8815
-
-
Sharabi, A.1
Zinger, H.2
Zborowsky, M.3
Sthoeger, Z.M.4
Mozes, E.5
-
28
-
-
77249141746
-
A new model of induced experimental systemic lupus erythematosus (SLE) in pigs and its amelioration by treatment with a tolerogenic peptide
-
Sharabi A, Dayan M, Zinger H, Mozes E. A new model of induced experimental systemic lupus erythematosus (SLE) in pigs and its amelioration by treatment with a tolerogenic peptide. J. Clin. Immunol. 30(1), 34-44 (2010
-
(2010)
J. Clin. Immunol
, vol.30
, Issue.1
, pp. 34-44
-
-
Sharabi, A.1
Dayan, M.2
Zinger, H.3
Mozes, E.4
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