Deficient fear conditioning in psychopathy as a function of interpersonal and affective disturbances

Frontiers in Human Neuroscience

Volumn , Issue OCT, 2013, Pages

  Veit, Ralf ^a   Konicar, Lilian ^a,b   Klinzing, Jens G ^b   Barth, Beatrix ^a   Yilmaz, Özge ^a,b   Birbaumer, Niels ^a,c  

^a UNIVERSITY OF TÜBINGEN   (Germany)

^b UNIVERSITY OF TÜBINGEN   (Germany)

^c IRCCS Ospedale San Camillo   (Italy)

Author keywords

Electrophysiology; Emotional cognitive interaction; Fear conditioning; Psychopathy; Skin conductance

Indexed keywords

ADULT; AMPLITUDE MODULATION; ARTICLE; CHECKLIST; CLINICAL ARTICLE; CONDITIONING; CONTROLLED STUDY; ELECTRIC SHOCK; ELECTROENCEPHALOGRAM; EVENT RELATED POTENTIAL; FEAR; FEAR CONDITIONING; HUMAN; MALE; MOOD DISORDER; OFFENDER; PSYCHOPATHY; PSYCHOPATHY CHECKLIST REVISED; SCORING SYSTEM; SKIN CONDUCTANCE; VIOLENCE;

EID: 84887957133     PISSN: 16625161     EISSN: None     Source Type: Journal    
DOI: 10.3389/fnhum.2013.00706     Document Type: Article

References (68)

1. Apa, (2000). Diagnostic and Statistical Manual of Mental Disorders. Text Revision (DSM-IV-TR). Washington, DC: American Psychiatric Association.
2. Baskin-Sommers, A. R., Curtin, J. J., and Newman, J. P. (2011). Specifying the attentional selection that moderates the fearlessness of psychopathic offenders. Psychol. Sci. 22, 226-234. doi: 10. 1177/0956797610396227.
3. Baskin-Sommers, A., Curtin, J. J., Li, W., and Newman, J. P. (2012). Psychopathy-related differences in selective attention are captured by an early event-related potential. Personal. Disord. 3, 370-378. doi: 10. 1037/a0025593.
4. Baskin-Sommers, A. R., Curtin, J. J., and Newman, J. P. (2013). Emotion-modulated startle in psychopathy: clarifying familiar effects. J. Abnorm. Psychol. 122, 458-468. doi: 10. 1037/a0030958.
5. Benedek, M., and Kaernbach, C. (2010). A continuous measure of phasic electrodermal activity. J. Neurosci. Methods 190, 80-91. doi: 10. 1016/j. jneumeth. 2010. 04. 028.
6. Birbaumer, N., Elbert, T., Canavan, A. G., and Rockstroh, B. (1990). Slow potentials of the cerebral cortex and behavior. Physiol. Rev. 70, 1-41.
7. Birbaumer, N., Veit, R., Lotze, M., Erb, M., Hermann, C., Grodd, W., et al. (2005). Deficient fear conditioning in psychopathy: a functional magnetic resonance imaging study. Arch. Gen. Psychiatry 62, 799-805. doi: 10. 1001/archpsyc. 62. 7. 799.
8. Bradley, M. M., and Lang, P. J. (1994). Measuring emotion: the self-assessment manikin and the semantic differential. J. Behav. Ther. Exp. Psychiatry 25, 49-59. doi: 10. 1016/0005-7916(94)90063-9.
9. Cleckley, H. (1941/1982). The Mask of Sanity. St. Louis, MO: C. V. Mosby.
10. Cooke, D. J., Hart, S. D., and Michie, C. (2004). Cross-national differences in the assessment of psychopathy: do they reflect variations in raters' perceptions of symptoms? Psychol. Assess. 16, 335-339. doi: 10. 1037/1040-3590. 16. 3. 335.
11. De Oliveira-Souza, R., Hare, R. D., Bramati, I. E., Garrido, G. J., Azevedo Ignacio, F., Tovar-Moll, F., et al. (2008). Psychopathy as a disorder of the moral brain: fronto-temporo-limbic grey matter reductions demonstrated by voxel-based morphometry. Neuroimage 40, 1202-1213. doi: 10. 1016/j. neuroimage. 2007. 12. 054.
12. Decety, J., Chen, C., Harenski, C., and Kiehl, K. A. (2013). An fMRI study of affective perspective taking in individuals with psychopathy: imaging another in pain does not evoke empathy. Front. Hum. Neurosci. 7: 489. doi: 10. 3389/fnhum. 2013. 00489.
13. Flor, H., Birbaumer, N., Hermann, C., Ziegler, S., and Patrick, C. J. (2002). Aversive Pavlovian conditioning in psychopaths: peripheral and central correlates. Psychophysiology 39, 505-518. doi: 10. 1111/1469-8986. 3940505.
14. Forth, A. E., and Hare, R. D. (1989). The contingent negative variation in psychopaths. Psychophysiology 26, 676-682. doi: 10. 1111/j. 1469-8986. 1989. tb03171. x.
15. Galderisi, S., Mucci, A., Volpe, U., and Boutros, N. (2009). Evidence-based medicine and electrophysiology in schizophrenia. Clin. EEG Neurosci. 40, 62-77. doi: 10. 1177/155005940904000206.
16. Gao, Y., and Raine, A. (2009). P3 event-related potential impairments in antisocial and psychopathic individuals: a meta-analysis. Biol. Psychol. 82, 199-210. doi: 10. 1016/j. biopsycho. 2009. 06. 006.
17. Gratton, G., Coles, M. G., and Donchin, E. (1983). A new method for off-line removal of ocular artifact. Electroencephalogr. Clin. Neurophysiol. 55, 468-484. doi: 10. 1016/0013-4694(83)90135-9.
18. Hare, R. D. (1965). Psychopathy, fear arousal and anticipated pain. Psychol. Rep. 16, 499-502. doi: 10. 2466/pr0. 1965. 16. 2. 499.
19. Hare, R. D. (1991). Hare Psychopathy Checklist-Revised. Toronto, ON: Multi-Health Systems. doi: 10. 4135/9781412959537. n134.
20. Hare, R. D. (2003). Hare Psychopathy Checklist-Revised, 2nd Edn. Toronto, ON: Multi-Health Systems.
21. Hare, R. D., and Quinn, M. J. (1971). Psychopathy and autonomic conditioning. J. Abnorm. Psychol. 77, 223-235. doi: 10. 1037/h0031012.
22. Hare, R. D., Frazelle, J., and Cox, D. N. (1978). Psychopathy and physiological responses to threat of an aversive stimulus. Psychophysiology 15, 165-172. doi: 10. 1111/j. 1469-8986. 1978. tb01356. x.
23. Hicks, B. M., and Patrick, C. J. (2006). Psychopathy and negative emotionality: analyses of suppressor effects reveal distinct relations with emotional distress, fearfulness, and anger-hostility. J. Abnorm. Psychol. 115, 276-287. doi: 10. 1037/0021-843X. 115. 2. 276.
24. Howard, R., and Mccullagh, P. (2007). Neuroaffective processing in criminal psychopaths: brain event-related potentials reveal task-specific anomalies. J. Pers. Disord. 21, 322-339. doi: 10. 1521/pedi. 2007. 21. 3. 322.
25. Jutai, J. W., and Hare, R. D. (1983). Psychopathy and selective attention during performance of a complex perceptual-motor task. Psychophysiology 20, 146-151. doi: 10. 1111/j. 1469-8986. 1983. tb03280. x.
26. Kiehl, K. A., Bates, A. T., Laurens, K. R., Hare, R. D., and Liddle, P. F. (2006). Brain potentials implicate temporal lobe abnormalities in criminal psychopaths. J. Abnorm. Psychol. 115, 443-453. doi: 10. 1037/0021-843X. 115. 3. 443.
27. Kiehl, K. A., Hare, R. D., Liddle, P. F., and Mcdonald, J. J. (1999). Reduced P300 responses in criminal psychopaths during a visual oddball task. Biol. Psychiatry 45, 1498-1507. doi: 10. 1016/S0006-3223(98)00193-0.
28. Kiehl, K. A., Smith, A. M., Hare, R. D., and Liddle, P. F. (2000). An event-related potential investigation of response inhibition in schizophrenia and psychopathy. Biol. Psychiatry 48, 210-221. doi: 10. 1016/S0006-3223(00)00834-9.
29. Lang, P. J., Bradley, M. M., Cuthbert, B. N., and Patrick, C. J. (1993). Emotion and psychopathology: a startle probe analysis. Prog. Exp. Pers. Psychopathol. Res. 16, 163-199.
30. Ledoux, J. E. (2000). Emotion circuits in the brain. Annu. Rev. Neurosci. 23, 155-184. doi: 10. 1146/annurev. neuro. 23. 1. 155.
31. Levenston, G. K., Patrick, C. J., Bradley, M. M., and Lang, P. J. (2000). The psychopath as observer: emotion and attention in picture processing. J. Abnorm. Psychol. 109, 373-385. doi: 10. 1037/0021-843X. 109. 3. 373.
32. Lilienfeld, S. O., and Widows, M. R. (2005). The Psychopathic Personality Inventory-Revised (PPI-R) Professional Manual. Lutz, FL: Psychological Assessement Ressources, Inc.
33. Lopez, R., Poy, R., Patrick, C. J., and Molto, J. (2013). Deficient fear conditioning and self-reported psychopathy: the role of fearless dominance. Psychophysiology 50, 210-218. doi: 10. 1111/j. 1469-8986. 2012. 01493. x.
34. Luck, S. J., Woodman, G. F., and Vogel, E. K. (2000). Event-related potential studies of attention. Trends Cogn. Sci. 4, 432-440. doi: 10. 1016/S1364-6613(00)01545-X.
35. Lumsden, J., Howard, R. C., and Fenton, G. W. (1986). The contingent negative variation (CNV) to fear-related stimuli in acquisition and extinction. Int. J. Psychophysiol. 3, 253-261. doi: 10. 1016/0167-8760(86)90034-6.
36. Marcus, D. K., Lilienfeld, S. O., Edens, J. F., and Poythress, N. G. (2006). Is antisocial personality disorder continuous or categorical? A taxometric analysis. Psychol. Med. 36, 1571-1581. doi: 10. 1017/S0033291706008245.
37. McCalloum, W. C. (1973). The CNV and conditionability in psychopaths. Electroencephalogr. Clin. Neurophysiol. 35, 337-343.
38. Miskovic, V., and Keil, A. (2012). Acquired fears reflected in cortical sensory processing: a review of electrophysiological studies of human classical conditioning. Psychophysiology 49, 1230-1241. doi: 10. 1111/j. 1469-8986. 2012. 01398. x.
39. Molto, J., Poy, R., Segarra, P., Pastor, M. C., and Montanes, S. (2007). Response perseveration in psychopaths: interpersonal/affective or social deviance traits? J. Abnorm. Psychol. 116, 632-637. doi: 10. 1037/0021-843X. 116. 3. 632.
40. Musil, R. (1930-1943). The Man Without Qualities. Berlin; Lausanne: Rowohl Verlag.
41. Newman, J. P., Curtin, J. J., Bertsch, J. D., and Baskin-Sommers, A. R. (2010). Attention moderates the fearlessness of psychopathic offenders. Biol. Psychiatry 67, 66-70. doi: 10. 1016/j. biopsych. 2009. 07. 035.
42. Ogloff, J. R. P., and Wong, S. (1990). Electrodermal and cardiovascular evidence of a coping response in psychopaths. Crim. Justice Behav. 17, 231-245. doi: 10. 1177/0093854890017002006.
43. Olofsson, J. K., Nordin, S., Sequeira, H., and Polich, J. (2008). Affective picture processing: an integrative review of ERP findings. Biol. Psychol. 77, 247-265. doi: 10. 1016/j. biopsycho. 2007. 11. 006.
44. Patrick, C. J. (1994). Emotion and psychopathy: startling new insights. Psychophysiology 31, 319-330. doi: 10. 1111/j. 1469-8986. 1994. tb02440. x.
45. Patrick, C. J., and Bernat, E. M. (2009). "Neurobiology of psychopathy: a two-process theory, " in Handbook of Neuroscience for the Behavioral Sciences, eds G. G. Berntson and J. T. Cacioppo (New York, NY: John Wiley and Sons), 1110-1132. doi: 10. 1002/9780470478509. neubb002057.
46. Patrick, C. J., Bernat, E. M., Malone, S. M., Iacono, W. G., Krueger, R. F., and Mcgue, M. (2006). P300 amplitude as an indicator of externalizing in adolescent males. Psychophysiology 43, 84-92. doi: 10. 1111/j. 1469-8986. 2006. 00376. x.
47. Patrick, C. J., Bradley, M. M., and Lang, P. J. (1993). Emotion in the criminal psychopath: startle reflex modulation. J. Abnorm. Psychol. 102, 82-92. doi: 10. 1037/0021-843X. 102. 1. 82.
48. Patrick, C. J., Hicks, B. M., Krueger, R. F., and Lang, A. R. (2005). Relations between psychopathy facets and externalizing in a criminal offender sample. J. Pers. Disord. 19, 339-356. doi: 10. 1521/pedi. 2005. 19. 4. 339.
49. Patrick, C. J., Hicks, B. M., Nichol, P. E., and Krueger, R. F. (2007). A bifactor approach to modeling the structure of the psychopathy checklist-revised. J. Pers. Disord. 21, 118-141. doi: 10. 1521/pedi. 2007. 21. 2. 118.
50. Raine, A., and Venables, P. H. (1987). Contingent negative variation, P3 evoked potentials, and antisocial behavior. Psychophysiology 24, 191-199. doi: 10. 1111/j. 1469-8986. 1987. tb00277. x.
51. Regan, M., and Howard, R. (1995). Fear conditioning, preparedness, and the contingent negative variation. Psychophysiology 32, 208-214. doi: 10. 1111/j. 1469-8986. 1995. tb02950. x.
52. Richell, R. A., Mitchell, D. G., Newman, C., Leonard, A., Baron-Cohen, S., and Blair, R. J. (2003). Theory of mind and psychopathy: can psychopathic individuals read the 'language of the eyes'? Neuropsychologia 41, 523-526. doi: 10. 1016/S0028-3932(02)00175-6.
53. Rockstroh, B., Elbert, T., Birbaumer, N., and Lutzenberger, W. (1982). Slow Brain Potentials and Behavior. Baltimore, MD: Urban and Schwarzenberg.
54. Rothemund, Y., Ziegler, S., Hermann, C., Gruesser, S. M., Foell, J., Patrick, C. J., et al. (2012). Fear conditioning in psychopaths: event-related potentials and peripheral measures. Biol. Psychol. 90, 50-59. doi: 10. 1016/j. biopsycho. 2012. 02. 011.
55. Sadeh, N., and Verona, E. (2012). Visual complexity attenuates emotional processing in psychopathy: implications for fear-potentiated startle deficits. Cogn. Affect. Behav. Neurosci. 12, 346-360. doi: 10. 3758/s13415-011-0079-1.
56. Schneider, F., Gur, R. C., Gur, R. E., and Muenz, L. R. (1994). Standardized mood induction with happy and sad facial expressions. Psychiatry Res. 51, 19-31. doi: 10. 1016/0165-1781(94)90044-2.
57. Schupp, H. T., Junghofer, M., Weike, A. I., and Hamm, A. O. (2004). The selective processing of briefly presented affective pictures: an ERP analysis. Psychophysiology41, 441-449. doi: 10. 1111/j. 1469-8986. 2004. 00174. x.
58. Sommer, M., Hajak, G., Dohnel, K., Schwerdtner, J., Meinhardt, J., and Muller, J. L. (2006). Integration of emotion and cognition in patients with psychopathy. Prog. Brain Res. 156, 457-466. doi: 10. 1016/S0079-6123(06)56025-X.
59. Strehl, U., Leins, U., Goth, G., Klinger, C., Hinterberger, T., and Birbaumer, N. (2006). Self-regulation of slow cortical potentials: a new treatment for children with attention-deficit/hyperactivity disorder. Pediatrics 118, e1530-e1540. doi: 10. 1542/peds. 2005-2478.
60. Sutton, S., Braren, M., Zubin, J., and John, E. R. (1965). Evoked-potential correlates of stimulus uncertainty. Science 150, 1187-1188. doi: 10. 1126/science. 150. 3700. 1187.
61. Tecce, J. J. (1972). Contingent negative variation (CNV) and psychological processes in man. Psychol. Bull. 77, 73-108. doi: 10. 1037/h0032177.
62. Vaidyanathan, U., Patrick, C. J., and Bernat, E. M. (2009a). Startle reflex potentiation during aversive picture viewing as an indicator of trait fear. Psychophysiology 46, 75-85. doi: 10. 1111/j. 1469-8986. 2008. 00751. x.
63. Vaidyanathan, U., Patrick, C. J., and Cuthbert, B. N. (2009b). Linking dimensional models of internalizing psychopathology to neurobiological systems: affect-modulated startle as an indicator of fear and distress disorders and affiliated traits. Psychol. Bull. 135, 909-942. doi: 10. 1037/a0017222.
64. Veit, R., Flor, H., Erb, M., Hermann, C., Lotze, M., Grodd, W., et al. (2002). Brain circuits involved in emotional learning in antisocial behavior and social phobia in humans. Neurosci. Lett. 328, 233-236. doi: 10. 1016/S0304-3940(02)00519-0.
65. Verleger, R., Jaskowski, P., and Wauschkuhn, B. (1994). Suspense and surprise: on the relationship between expectancies and P3. Psychophysiology 31, 359-369. doi: 10. 1111/j. 1469-8986. 1994. tb02444. x.
66. Vollm, B. A., Taylor, A. N., Richardson, P., Corcoran, R., Stirling, J., Mckie, S., et al. (2006). Neuronal correlates of theory of mind and empathy: a functional magnetic resonance imaging study in a nonverbal task. Neuroimage 29, 90-98. doi: 10. 1016/j. neuroimage. 2005. 07. 022.
67. Walter, W. G., Cooper, R., Aldridge, V. J., Mccallum, W. C., and Winter, A. L. (1964). Contingent negative variation: an electric sign of sensorimotor association and expectancy in the human brain. Nature 203, 380-384. doi: 10. 1038/203380a0.
68. Yang, Y., Raine, A., Narr, K. L., Colletti, P., and Toga, A. W. (2009). Localization of deformations within the amygdala in individuals with psychopathy. Arch. Gen. Psychiatry 66, 986-994. doi: 10. 1001/archgenpsychiatry. 2009. 110.